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The map label for this gene is helD [H]

Identifier: 220915992

GI number: 220915992

Start: 993670

End: 995784

Strand: Direct

Name: helD [H]

Synonym: A2cp1_0878

Alternate gene names: 220915992

Gene position: 993670-995784 (Clockwise)

Preceding gene: 220915984

Following gene: 220915993

Centisome position: 19.76

GC content: 78.58

Gene sequence:

>2115_bases
TTGCGAGCGATCCCTGCCAGCCCGGCGCCCGTTCTCGAGGGCGACACGCTCACCGCGGCGGCGCGCGCCATCGTGGCCGA
GGAGGAGGCGCTCCTCGCCACCGTGCAGCGGGCGCTCGCGGCCCGGCTCGCGCCGGCGCGCGGGGAGGGCGATCTGGTCG
GGCGCCTGAGGGACCTGCGCGACGAGGCGCTGGAGGCGACGCCCAAGGACCTGCCCACGGTCTTCCAGGAGATGGGCCTC
CTGCGCGCGGTGATGGAGCGCGTCCGCCCCGACCAGCTCCCGGACCCCGCCGCGCCGTACTTCGCGCACCTGCGCGTGCA
CGAGGGCGGCGAGCGGCGCGACTACTTCCTCGGCCGCCACACGTTCGTGGACCGGCCCGCCGGCGTGCGCGTGGTGGACT
GGCGGTTCGCGCCGGTGGCCGGGATCTTCTATCGCTACCGGGAGGGCGAGGAGTTCGAGGAGGCGTTCCCGGGCCGGGTC
GCCACCGGCACGGTGGAGGCGCGGCGGGTGGTGGTGGTGGAGCGCGGGGTGCTGACCCGGATCGCGGCCGGCCCGCTGAC
GCTGGTGCGCGAGGGCGGGCGGTGGCGGGCGCTGGCCGCCGAGGCGGCGGCGCTGGGCGGCGGGGCGGGGTCGGCGGCGC
GCGCCGGCGCGCTCGGGACCGGCGCCGGCGCGGCCGGCCGCGCGGGTCCGGCCGACATCACCGCGCTGCTCGATCCGGAC
CAGTACGAGGCGGTCGCCGCGCCCGCGGACCGCCCGCTGCTCGTGCTCGGCTCCGCCGGCAGCGGCAAGACCACCGTCGC
GCTGCACCGGCTCGCCCGGATCGCCTTCGAGGACCCGCGGCGCTTCCCGCCGGCGCGGCTGCAGGTGGTGGTGCCGGAGC
TCGGCCTGGCCCGGCTCGCGGCGCGGCTGCTCGAGCCGCTCGGCCTGGAGCGGTCGCCGGTCCGGACGCTCGAGTCCTGG
TCGCGCGGCGCGTTCCAGAGCGTGTTCGGCGCCCCGCCGCCGCGCCTGTTCCCGGAGACGCCGCCGCTCGTCGCCCGGCT
GAAGCGCCACCCGGCGCTCTACGAGCTGCTCCGCCGCCGGCCGCACGTCGCCCGGGAGCGGCCGGCCCTGGCGCGGCTGC
GCCGCGAGCTCGGCGACCTGTTCGTCGATCGCGGGTTCCTGGAGGCGGTGGTGAAGGCGGCCGCGGGGACGCTGCCGGCG
ACCGCCGTCGACGAGACGCTCCGCCACACGCGGCTGCAGCTCTCCTCCTCGACCGAGGACCTGCTGGCGGGCGTGGACCC
GGAGCGGCTCCAGACGCTGGACGGGAAGGCGGTGGACGAGGACACGCCCGAGGCCGCCGCCGGCACGCTCGACGTCGAGG
ACCTGCCCATCCTGCTGTTCCTCGCGGCGCTCCGGGCGGGCGCGCCGGCGCGGAAGGCGGCGCACCTGGTGGTGGACGAG
GCGGAGGACGTGACGCTGTTCGAGCTGCACGTGCTCGGGCGGCACCTCGCCGGCACCAGCGTCACGCTCGCGGGCGACGA
GAGCCAGCAGACCTTCGCGTCCTACGCCGGCTGGCCGCAGGCGCTCGCCGCGCTCGGCGCGCCGGCGGCGGCCACGGTGC
GCCTCGCGACGACCTACCGCTGCCCGGAGCCGGTCGCGGCGCTGGCCCACGCCGTGCTCGGGCCGATCGCCCCGCCGGAG
CGGCCGCGCGCCGGCCGGCGCGGCGCCCCCGTGTCGCGCTTCGACTTCCCCACCGAGGCGCACGCCCACCTGTTCCTGGC
GGGCGCGCTGCGCGACCTGGTGGAGCGGGAGCCGGGCGCGTCCGCCGCGGTGGTGTGCAGCGGGCCCGAGGTCGCGCGCA
GCCTGCACCGGCTGCTGGCCGACATGCCGGAGGCGAGGCTCTCGCTCGACGGCGCGTTCACGTTCCGTCCAGGGGTGGAC
CTCACCGACGTCGACGGCGTGAAGGGGCTCGAGTTCGACTACGTGGTGGTGCCGGACGCCACCGCCCGCGCCTACCCCGA
GACCGACGAGGCGCGCCGCCGGCTCCACGTGGCCGTGACCCGGGCCGCCCACCAGCTCTGGATCGCGGCGCCGGGCACGC
CCTCGCCGCTGCTGCGCGGCCTGCCGCGCGGCTGA

Upstream 100 bases:

>100_bases
GCGGTGCTGCTCCGGTGGGCAGGCGGCGCCGCGCGGCCGCGCAAGCGCTGCGCGCGGGCGCGTCGTGCGCCCGTCGGAGA
GCCCGCTTAAGCTAGACCGC

Downstream 100 bases:

>100_bases
CCGTGCGCGCCGCGGTCCCGGAAGGGGCTGCGGGCGTCGAACGGGTAAGCGAGCGTTCAGCAGCCGGACTAGATTCGGGG
CACCGAGCATCCGAATCCGG

Product: superfamily I DNA and RNA helicase-like protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 704; Mature: 704

Protein sequence:

>704_residues
MRAIPASPAPVLEGDTLTAAARAIVAEEEALLATVQRALAARLAPARGEGDLVGRLRDLRDEALEATPKDLPTVFQEMGL
LRAVMERVRPDQLPDPAAPYFAHLRVHEGGERRDYFLGRHTFVDRPAGVRVVDWRFAPVAGIFYRYREGEEFEEAFPGRV
ATGTVEARRVVVVERGVLTRIAAGPLTLVREGGRWRALAAEAAALGGGAGSAARAGALGTGAGAAGRAGPADITALLDPD
QYEAVAAPADRPLLVLGSAGSGKTTVALHRLARIAFEDPRRFPPARLQVVVPELGLARLAARLLEPLGLERSPVRTLESW
SRGAFQSVFGAPPPRLFPETPPLVARLKRHPALYELLRRRPHVARERPALARLRRELGDLFVDRGFLEAVVKAAAGTLPA
TAVDETLRHTRLQLSSSTEDLLAGVDPERLQTLDGKAVDEDTPEAAAGTLDVEDLPILLFLAALRAGAPARKAAHLVVDE
AEDVTLFELHVLGRHLAGTSVTLAGDESQQTFASYAGWPQALAALGAPAAATVRLATTYRCPEPVAALAHAVLGPIAPPE
RPRAGRRGAPVSRFDFPTEAHAHLFLAGALRDLVEREPGASAAVVCSGPEVARSLHRLLADMPEARLSLDGAFTFRPGVD
LTDVDGVKGLEFDYVVVPDATARAYPETDEARRRLHVAVTRAAHQLWIAAPGTPSPLLRGLPRG

Sequences:

>Translated_704_residues
MRAIPASPAPVLEGDTLTAAARAIVAEEEALLATVQRALAARLAPARGEGDLVGRLRDLRDEALEATPKDLPTVFQEMGL
LRAVMERVRPDQLPDPAAPYFAHLRVHEGGERRDYFLGRHTFVDRPAGVRVVDWRFAPVAGIFYRYREGEEFEEAFPGRV
ATGTVEARRVVVVERGVLTRIAAGPLTLVREGGRWRALAAEAAALGGGAGSAARAGALGTGAGAAGRAGPADITALLDPD
QYEAVAAPADRPLLVLGSAGSGKTTVALHRLARIAFEDPRRFPPARLQVVVPELGLARLAARLLEPLGLERSPVRTLESW
SRGAFQSVFGAPPPRLFPETPPLVARLKRHPALYELLRRRPHVARERPALARLRRELGDLFVDRGFLEAVVKAAAGTLPA
TAVDETLRHTRLQLSSSTEDLLAGVDPERLQTLDGKAVDEDTPEAAAGTLDVEDLPILLFLAALRAGAPARKAAHLVVDE
AEDVTLFELHVLGRHLAGTSVTLAGDESQQTFASYAGWPQALAALGAPAAATVRLATTYRCPEPVAALAHAVLGPIAPPE
RPRAGRRGAPVSRFDFPTEAHAHLFLAGALRDLVEREPGASAAVVCSGPEVARSLHRLLADMPEARLSLDGAFTFRPGVD
LTDVDGVKGLEFDYVVVPDATARAYPETDEARRRLHVAVTRAAHQLWIAAPGTPSPLLRGLPRG
>Mature_704_residues
MRAIPASPAPVLEGDTLTAAARAIVAEEEALLATVQRALAARLAPARGEGDLVGRLRDLRDEALEATPKDLPTVFQEMGL
LRAVMERVRPDQLPDPAAPYFAHLRVHEGGERRDYFLGRHTFVDRPAGVRVVDWRFAPVAGIFYRYREGEEFEEAFPGRV
ATGTVEARRVVVVERGVLTRIAAGPLTLVREGGRWRALAAEAAALGGGAGSAARAGALGTGAGAAGRAGPADITALLDPD
QYEAVAAPADRPLLVLGSAGSGKTTVALHRLARIAFEDPRRFPPARLQVVVPELGLARLAARLLEPLGLERSPVRTLESW
SRGAFQSVFGAPPPRLFPETPPLVARLKRHPALYELLRRRPHVARERPALARLRRELGDLFVDRGFLEAVVKAAAGTLPA
TAVDETLRHTRLQLSSSTEDLLAGVDPERLQTLDGKAVDEDTPEAAAGTLDVEDLPILLFLAALRAGAPARKAAHLVVDE
AEDVTLFELHVLGRHLAGTSVTLAGDESQQTFASYAGWPQALAALGAPAAATVRLATTYRCPEPVAALAHAVLGPIAPPE
RPRAGRRGAPVSRFDFPTEAHAHLFLAGALRDLVEREPGASAAVVCSGPEVARSLHRLLADMPEARLSLDGAFTFRPGVD
LTDVDGVKGLEFDYVVVPDATARAYPETDEARRRLHVAVTRAAHQLWIAAPGTPSPLLRGLPRG

Specific function: Catalyzes the unwinding of duplex DNA in the 3' to 5' direction; this reaction is dependent on the hydrolysis of ATP [H]

COG id: COG3973

COG function: function code R; Superfamily I DNA and RNA helicases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 uvrD-like helicase ATP-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000212
- InterPro:   IPR014016 [H]

Pfam domain/function: PF00580 UvrD-helicase [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 75148; Mature: 75148

Theoretical pI: Translated: 7.13; Mature: 7.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
0.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRAIPASPAPVLEGDTLTAAARAIVAEEEALLATVQRALAARLAPARGEGDLVGRLRDLR
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHH
DEALEATPKDLPTVFQEMGLLRAVMERVRPDQLPDPAAPYFAHLRVHEGGERRDYFLGRH
HHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEECCCCCCCEEECCH
TFVDRPAGVRVVDWRFAPVAGIFYRYREGEEFEEAFPGRVATGTVEARRVVVVERGVLTR
HCCCCCCCCEEEEEECHHHHHHHHHHCCCCHHHHHCCCCEEECCCCCEEEEEEECCHHHH
IAAGPLTLVREGGRWRALAAEAAALGGGAGSAARAGALGTGAGAAGRAGPADITALLDPD
HHCCCCCEEECCCCEEHHHHHHHHCCCCCCCHHHCCCCCCCCCCCCCCCCCCEEEEECCC
QYEAVAAPADRPLLVLGSAGSGKTTVALHRLARIAFEDPRRFPPARLQVVVPELGLARLA
HHHEEECCCCCCEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCHHHHH
ARLLEPLGLERSPVRTLESWSRGAFQSVFGAPPPRLFPETPPLVARLKRHPALYELLRRR
HHHHHHCCCCCCHHHHHHHHCCHHHHHHHCCCCCCCCCCCCHHHHHHHCCHHHHHHHHCC
PHVARERPALARLRRELGDLFVDRGFLEAVVKAAAGTLPATAVDETLRHTRLQLSSSTED
CCHHHCCHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCHHH
LLAGVDPERLQTLDGKAVDEDTPEAAAGTLDVEDLPILLFLAALRAGAPARKAAHLVVDE
HHHCCCHHHHHHCCCCCCCCCCCCHHCCCCCCCHHHHHHHHHHHHCCCCHHHHHEEEEEC
AEDVTLFELHVLGRHLAGTSVTLAGDESQQTFASYAGWPQALAALGAPAAATVRLATTYR
CCCCEEEHHHHHHHHHCCCEEEEECCCHHHHHHHHCCHHHHHHHHCCCCHHEEEEEEECC
CPEPVAALAHAVLGPIAPPERPRAGRRGAPVSRFDFPTEAHAHLFLAGALRDLVEREPGA
CCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCC
SAAVVCSGPEVARSLHRLLADMPEARLSLDGAFTFRPGVDLTDVDGVKGLEFDYVVVPDA
CEEEEECCHHHHHHHHHHHHHCCHHHEECCCEEEECCCCCCCCCCCCCCCCEEEEECCCC
TARAYPETDEARRRLHVAVTRAAHQLWIAAPGTPSPLLRGLPRG
CCCCCCCCHHHHHHHHHHHHHHHHEEEEECCCCCCHHHHCCCCC
>Mature Secondary Structure
MRAIPASPAPVLEGDTLTAAARAIVAEEEALLATVQRALAARLAPARGEGDLVGRLRDLR
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHH
DEALEATPKDLPTVFQEMGLLRAVMERVRPDQLPDPAAPYFAHLRVHEGGERRDYFLGRH
HHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEECCCCCCCEEECCH
TFVDRPAGVRVVDWRFAPVAGIFYRYREGEEFEEAFPGRVATGTVEARRVVVVERGVLTR
HCCCCCCCCEEEEEECHHHHHHHHHHCCCCHHHHHCCCCEEECCCCCEEEEEEECCHHHH
IAAGPLTLVREGGRWRALAAEAAALGGGAGSAARAGALGTGAGAAGRAGPADITALLDPD
HHCCCCCEEECCCCEEHHHHHHHHCCCCCCCHHHCCCCCCCCCCCCCCCCCCEEEEECCC
QYEAVAAPADRPLLVLGSAGSGKTTVALHRLARIAFEDPRRFPPARLQVVVPELGLARLA
HHHEEECCCCCCEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCHHHHH
ARLLEPLGLERSPVRTLESWSRGAFQSVFGAPPPRLFPETPPLVARLKRHPALYELLRRR
HHHHHHCCCCCCHHHHHHHHCCHHHHHHHCCCCCCCCCCCCHHHHHHHCCHHHHHHHHCC
PHVARERPALARLRRELGDLFVDRGFLEAVVKAAAGTLPATAVDETLRHTRLQLSSSTED
CCHHHCCHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCHHH
LLAGVDPERLQTLDGKAVDEDTPEAAAGTLDVEDLPILLFLAALRAGAPARKAAHLVVDE
HHHCCCHHHHHHCCCCCCCCCCCCHHCCCCCCCHHHHHHHHHHHHCCCCHHHHHEEEEEC
AEDVTLFELHVLGRHLAGTSVTLAGDESQQTFASYAGWPQALAALGAPAAATVRLATTYR
CCCCEEEHHHHHHHHHCCCEEEEECCCHHHHHHHHCCHHHHHHHHCCCCHHEEEEEEECC
CPEPVAALAHAVLGPIAPPERPRAGRRGAPVSRFDFPTEAHAHLFLAGALRDLVEREPGA
CCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCC
SAAVVCSGPEVARSLHRLLADMPEARLSLDGAFTFRPGVDLTDVDGVKGLEFDYVVVPDA
CEEEEECCHHHHHHHHHHHHHCCHHHEECCCEEEECCCCCCCCCCCCCCCCEEEEECCCC
TARAYPETDEARRRLHVAVTRAAHQLWIAAPGTPSPLLRGLPRG
CCCCCCCCHHHHHHHHHHHHHHHHEEEEECCCCCCHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]