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The map label for this gene is ppnK [H]

Identifier: 220915884

GI number: 220915884

Start: 862879

End: 863727

Strand: Direct

Name: ppnK [H]

Synonym: A2cp1_0768

Alternate gene names: 220915884

Gene position: 862879-863727 (Clockwise)

Preceding gene: 220915881

Following gene: 220915885

Centisome position: 17.16

GC content: 69.96

Gene sequence:

>849_bases
ATGCTCCGCATGGACGGCCATCCGTGTCCCGTGCCGAAGCGCGTGGGGATCGTGCACAAGGTCTCGAGCGCCGAGGCGTC
GGAGACGGCGGTGTACGTGGGGCAGTTCCTCGAGGGGAAGGGCGTCGAGGTGCTCCGCGACGAGGCGGAGGTGGCGCGCT
CCGCCGACCTGGTGGTGGTGCTCGGCGGCGACGGCACGCTCATCCACGCCGCCGGCCTGCTCGACGGCCGCCCGGTGCCC
ATCCTCGGCGTGAACATGGGGAGCCTCGGCTTCATGACCGAGGTCCCGCAGAGCGGCATGTACGCGGCGATGGACGACGT
GCTGGCCGGGCGCGCCACGCTGTCCGAGCGCATGAAGCTGCGCGTGCACCTGCACCGCGGCGGCAGCTCCGAGCGCGCGC
TCGACGCCGAGGTGCTGAACGACGTGGTGATCGCGAAGGGCGCGCTGTCGCGCATGGTCGAGCTCGACACCCGCTGCTCC
GGCGAGTACGTCACGACCTACAAGGCGGACGGCATCATCGTCGCGACGCCCACCGGCTCGACCGCCTACGCGCTCGCCGC
GAACGGGCCCATCATGTACCCGACCATGCGCGGCGTGATCATCGCGCCGATCTGCCCGCACATGCTCACGCAGCGGCCGC
TGGTGGTGCCGGACGAGGAGAAGATCGAGATCCTGCTGGTGAACGACAGCGAGGTCTTCATGACGCTGGACGGCCAGAGC
GGCGTGAAGCTCGAGCGCGGCGACCGGATCCAGGTGAAGCAGTCGTACAACCGCGTGCTGCTGGTGCGGAACAAGTCGCT
CGACTTCTTCGGGATCCTGCGCGCGAAGCTGCGCTGGGGCGAGCGCTGA

Upstream 100 bases:

>100_bases
AATCCTCCAGGCGGCGGGGGCGCATCCGCTCGGCGAGCGGCTTGCCGCTCGGGTCGTCCGCGACGGCGCGATCGAAGAGG
TCCATGAAACCGCTTATATA

Downstream 100 bases:

>100_bases
GCGACGCGCCCTGAACGGGCCGACCACTGAAAATTTGCGCAGCGTCAGGGGCCCGTGGATCATGGGCCCATGCTCACGAC
GCTGCGCATCTCCGGCCTCG

Product: ATP-NAD/AcoX kinase

Products: NA

Alternate protein names: Poly(P)/ATP NAD kinase [H]

Number of amino acids: Translated: 282; Mature: 282

Protein sequence:

>282_residues
MLRMDGHPCPVPKRVGIVHKVSSAEASETAVYVGQFLEGKGVEVLRDEAEVARSADLVVVLGGDGTLIHAAGLLDGRPVP
ILGVNMGSLGFMTEVPQSGMYAAMDDVLAGRATLSERMKLRVHLHRGGSSERALDAEVLNDVVIAKGALSRMVELDTRCS
GEYVTTYKADGIIVATPTGSTAYALAANGPIMYPTMRGVIIAPICPHMLTQRPLVVPDEEKIEILLVNDSEVFMTLDGQS
GVKLERGDRIQVKQSYNRVLLVRNKSLDFFGILRAKLRWGER

Sequences:

>Translated_282_residues
MLRMDGHPCPVPKRVGIVHKVSSAEASETAVYVGQFLEGKGVEVLRDEAEVARSADLVVVLGGDGTLIHAAGLLDGRPVP
ILGVNMGSLGFMTEVPQSGMYAAMDDVLAGRATLSERMKLRVHLHRGGSSERALDAEVLNDVVIAKGALSRMVELDTRCS
GEYVTTYKADGIIVATPTGSTAYALAANGPIMYPTMRGVIIAPICPHMLTQRPLVVPDEEKIEILLVNDSEVFMTLDGQS
GVKLERGDRIQVKQSYNRVLLVRNKSLDFFGILRAKLRWGER
>Mature_282_residues
MLRMDGHPCPVPKRVGIVHKVSSAEASETAVYVGQFLEGKGVEVLRDEAEVARSADLVVVLGGDGTLIHAAGLLDGRPVP
ILGVNMGSLGFMTEVPQSGMYAAMDDVLAGRATLSERMKLRVHLHRGGSSERALDAEVLNDVVIAKGALSRMVELDTRCS
GEYVTTYKADGIIVATPTGSTAYALAANGPIMYPTMRGVIIAPICPHMLTQRPLVVPDEEKIEILLVNDSEVFMTLDGQS
GVKLERGDRIQVKQSYNRVLLVRNKSLDFFGILRAKLRWGER

Specific function: Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus [H]

COG id: COG0061

COG function: function code G; Predicted sugar kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAD kinase family [H]

Homologues:

Organism=Homo sapiens, GI55743112, Length=274, Percent_Identity=32.4817518248175, Blast_Score=131, Evalue=8e-31,
Organism=Escherichia coli, GI1788968, Length=289, Percent_Identity=29.4117647058824, Blast_Score=144, Evalue=9e-36,
Organism=Saccharomyces cerevisiae, GI6320794, Length=244, Percent_Identity=31.1475409836066, Blast_Score=138, Evalue=9e-34,
Organism=Saccharomyces cerevisiae, GI6325068, Length=213, Percent_Identity=33.3333333333333, Blast_Score=131, Evalue=1e-31,
Organism=Saccharomyces cerevisiae, GI6322509, Length=242, Percent_Identity=28.5123966942149, Blast_Score=124, Evalue=1e-29,
Organism=Drosophila melanogaster, GI28573828, Length=247, Percent_Identity=35.2226720647773, Blast_Score=128, Evalue=4e-30,
Organism=Drosophila melanogaster, GI28573832, Length=247, Percent_Identity=35.2226720647773, Blast_Score=128, Evalue=5e-30,
Organism=Drosophila melanogaster, GI28573826, Length=247, Percent_Identity=35.2226720647773, Blast_Score=127, Evalue=6e-30,
Organism=Drosophila melanogaster, GI161077047, Length=247, Percent_Identity=35.2226720647773, Blast_Score=127, Evalue=6e-30,
Organism=Drosophila melanogaster, GI28573830, Length=247, Percent_Identity=35.2226720647773, Blast_Score=127, Evalue=6e-30,
Organism=Drosophila melanogaster, GI20129957, Length=272, Percent_Identity=31.9852941176471, Blast_Score=121, Evalue=5e-28,
Organism=Drosophila melanogaster, GI281363323, Length=272, Percent_Identity=31.9852941176471, Blast_Score=121, Evalue=7e-28,
Organism=Drosophila melanogaster, GI24653422, Length=272, Percent_Identity=31.9852941176471, Blast_Score=120, Evalue=7e-28,
Organism=Drosophila melanogaster, GI281363321, Length=272, Percent_Identity=31.9852941176471, Blast_Score=120, Evalue=8e-28,
Organism=Drosophila melanogaster, GI24653424, Length=272, Percent_Identity=31.9852941176471, Blast_Score=120, Evalue=8e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016064
- InterPro:   IPR017438
- InterPro:   IPR017437
- InterPro:   IPR002504 [H]

Pfam domain/function: PF01513 NAD_kinase [H]

EC number: =2.7.1.23 [H]

Molecular weight: Translated: 30523; Mature: 30523

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLRMDGHPCPVPKRVGIVHKVSSAEASETAVYVGQFLEGKGVEVLRDEAEVARSADLVVV
CCCCCCCCCCCCCCCCEEEEECCCCCCHHEEEEEHHCCCCCHHHHHHHHHHHCCCCEEEE
LGGDGTLIHAAGLLDGRPVPILGVNMGSLGFMTEVPQSGMYAAMDDVLAGRATLSERMKL
ECCCCCEEEEECCCCCCCCCEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCEEE
RVHLHRGGSSERALDAEVLNDVVIAKGALSRMVELDTRCSGEYVTTYKADGIIVATPTGS
EEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCEEEEECCCCC
TAYALAANGPIMYPTMRGVIIAPICPHMLTQRPLVVPDEEKIEILLVNDSEVFMTLDGQS
EEEEEECCCCEEECCCCCEEEECCCHHHHCCCCCCCCCCCCEEEEEEECCEEEEEECCCC
GVKLERGDRIQVKQSYNRVLLVRNKSLDFFGILRAKLRWGER
CCEECCCCEEEEEECCCEEEEEECCCCCHHHHHHHHHHCCCC
>Mature Secondary Structure
MLRMDGHPCPVPKRVGIVHKVSSAEASETAVYVGQFLEGKGVEVLRDEAEVARSADLVVV
CCCCCCCCCCCCCCCCEEEEECCCCCCHHEEEEEHHCCCCCHHHHHHHHHHHCCCCEEEE
LGGDGTLIHAAGLLDGRPVPILGVNMGSLGFMTEVPQSGMYAAMDDVLAGRATLSERMKL
ECCCCCEEEEECCCCCCCCCEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCEEE
RVHLHRGGSSERALDAEVLNDVVIAKGALSRMVELDTRCSGEYVTTYKADGIIVATPTGS
EEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCEEEEECCCCC
TAYALAANGPIMYPTMRGVIIAPICPHMLTQRPLVVPDEEKIEILLVNDSEVFMTLDGQS
EEEEEECCCCEEECCCCCEEEECCCHHHHCCCCCCCCCCCCEEEEEEECCEEEEEECCCC
GVKLERGDRIQVKQSYNRVLLVRNKSLDFFGILRAKLRWGER
CCEECCCCEEEEEECCCEEEEEECCCCCHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA