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The map label for this gene is pilQ [H]

Identifier: 220915798

GI number: 220915798

Start: 757321

End: 759984

Strand: Direct

Name: pilQ [H]

Synonym: A2cp1_0679

Alternate gene names: 220915798

Gene position: 757321-759984 (Clockwise)

Preceding gene: 220915797

Following gene: 220915799

Centisome position: 15.06

GC content: 72.26

Gene sequence:

>2664_bases
ATGACTTCCCGCCTGAAGCCCATCGTCGGCCTGCTCCTGTGGGGCGCGATCAGCGCCGCCACCGCGGCCGAGCCGAACGT
CATCCGTGGGATCGAGGTCGGGCAGCGCGAGGGCGCGCTCGAGCTCGAGATCCGCGGCTCGCGCGCCCCGTCCTACTCGG
TGTTCAAGCTCCAGGATCCGCCGCGCCTGGTCGTGGACCTGGCTGGTGCCGACGTGTCCGGGGTGGGCTCTCCCATCCAG
GTCGGCAAGGCCGGCGTGCTCGCGGTGAGCACCGCCCAGTACAAGGACGAGCGGAGCGCGGTCGGCCGCGTGATCATCGC
GCTCGACGGCGCGCGCCGCTACGACGTGGCGCCGCGCGGCGATGCCGTGGTCGTTCGGGTGCTCGAGGCCGAGACCGCGG
GTGCCCCCGCCGCAGCGGCGGCGTCCTCCCCGGCGGCGACCGCTCCCGCGGCGCCGCCCGCGTCGGTGCCCGCCGCGCCT
TCGCCCTCGGGCGACGGTCACCTGGTCTCGCGCCGCGTCGACGAGGGCCCGGGCGGCACCGCCACCCGCATCACCGGGGT
GCGCGCCGCCGGCGCCCAGCTCGTCATCGCCACCGATGGCGAGCCGGGGCGCCTCGAGATCCTCGAGCTGCGCGATCCGG
CGCGCCTCGCCATCGACGTCCACGGCGTGGCCAGCGCGCCGCGCGCGCCGGTCAAGGTGCGCGGTGCGTTCTCGCAGGTC
CGGTTCGGCCGCGATTCCGGCAAGGTGCGCGTGGTGCTCGACGCGTCCGGCGCCCTGCCCCGGTACGAGGTGAAGCGCGT
GGCCGGCGGCGTGGCCGTGGTCACCTCCGGAGCCTCGGTCGCGTCGGCCGAGCCGGCGCGCAAGGCCGCCCCGGCGCCCG
GGGTCGAGCCTGTCGTCGCGGCCGCTCCCGCGGCGCCGACGGCGGATCCCGGCCTGGCCCGCATCGCCGACGTCCGCTTC
GCCAGCGCGGGCGGCGGGTCGCGCATCGACATCGCCGGCAAGGCGCCGTTCGTGATCTCCCGCCCCGACGCGCGCACGGT
GGTGCTGACGCTCGATGGCGCGAAGCTGCCCCGCGCGATGGAGCGCTCGCTCGACACCACCGCCTTCCACGGCCCGGTGG
CCATGGTCTCGTCCTTCAACCAGCCACAGACGGGGCAGGTCCGCATCGTGGCCACGCTGCGCGGGTCCGCCACCGATCGG
ATCGTCGAGACGCGGGACGGCCTCACCTGGACCTTCACCGAAGGCGGTGACGCGGCCGAGGCCGCTGCGCCGGCCATGCC
CGAGCAGGCCCAGGCCGCCGACGCGAAGGTGGCGGGCTTCGCCGCCGAGGCGCCGGCGTACGCCTCGTCCGGCGCGCCCC
AGGCTCGCGGCTACAGCGGCCGGCGCATCACGCTCGACTTCCACGACATCGAGATCCGCAACCTGCTCCGGCTCATCGCC
GATGTCTCCAAGAAGAACATCGTGGTGGCCGACGACGTGTCCGGCAAGGTCACCGTCTCGCTCCGCAACGTGCCCTGGGA
TCAGGCGCTCGACCTGGTCCTGCGCTCCAAGGGGCTCGGCAAGGAGGAGATGGGCAACGTGATCCGCATCGCGAAGTTCG
AAGCGATCGCCAAGGAGCAGGCGGCGAAGGCCGAGGCCGAGAAGGCACGCATCCCGCTCATCCCGTTGAAGGTGCGCATC
ATCCCGGTGAACTACGCCCGCGCCGCCGACGTGGCGAGCCGGGTGAAGGACGTGCTCTCCGAGCGCGGCTCGGTCTCGAC
CGACGAGCGCACGAACGTGCTCATCGTGAAGGACATCCCGGAGGCGCTGGTCCGGGCCGAGGGCCTGGTGCGGAACCTCG
ACACCGAGATCCCGCAGGTGCTCATCGAGAGCCGAATCGTGGAGGCCTCCTCCAACTTCAACCGGCAGCTCGGCGTGCAG
TGGGGCGGCAACGCCTCCTTCACGCAGGCCACCGGCAATCCCACCGGCGTCGCCTTCCCCAACAACGTCTCGGGCGCCGG
CGCGGCCGGCCAGGCGCCGAACCAGGGCACGTCGAGCACGCCGAACTACGCCGTGAACCTCCCGGCCGCCATCGGCCAGG
GCTCCGGCGGCGGCATCGGCCTGGTGCTCGGCTCGGCGAACGGCGCGTTCAACCTGAACCTGCGCCTCTCCGCGCTCGAG
AACAACGGCGTGGTGAAGACCATCTCCTCGCCCAAGATCGCCACCATCGACAACAAGGAGGCGACCATCGGGCAGGGCAT
CTCGATCCCGTTCTCGCAGACCTCCGCGTCGGGCGTGAACACCACCTTCGTCGAGGCGAAGCTGGAGCTGAAGGTCACGC
CGCACGTGACCGCCGACGGCTCCATCCTCCTCAAGATCAAGGCGACCAACAACGCGCCGAACTCGTCGCTGACGGGCTCG
AACGGGCAGCCCTCGATCTCGAAGCGCGAGGCCGAGACCGAGGTGCTCGTGAAGGACGGCGAGACCACCGTCATCGGCGG
CATCTACACCCGCTCCACGGCCTCGAAGACTGCGTCGGTGCCGTTCCTCAGCAAGATCCCGCTGCTCGGATTCTTCTTCC
GGAGCGACACCAACACCGACGACCACACCGAGCTGCTCATCTTCATCACGCCGCGCATCCTGAACCGGCAGCCGGCGACG
GCCGCGGCGGCCGCGAGCAACTAG

Upstream 100 bases:

>100_bases
TGACCGAGTTCGCCCTGCGCGCCGATGGGACCCGTGATCGAACCCAGACGGTGCTCCGCCTCCCCAAGGAAGCGGCGCTC
AACCTCGAGGAGCAGCTCCC

Downstream 100 bases:

>100_bases
GAGCCAGCCATGAAGACGCGACTCGCGACCCTCCTCCTCGCCACGGCGGCCCTCGCCTGCACGGTGGACAACAACGCCTC
GATCCAGGTGGTGGCCCTGT

Product: type IV pilus secretin PilQ

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 887; Mature: 886

Protein sequence:

>887_residues
MTSRLKPIVGLLLWGAISAATAAEPNVIRGIEVGQREGALELEIRGSRAPSYSVFKLQDPPRLVVDLAGADVSGVGSPIQ
VGKAGVLAVSTAQYKDERSAVGRVIIALDGARRYDVAPRGDAVVVRVLEAETAGAPAAAAASSPAATAPAAPPASVPAAP
SPSGDGHLVSRRVDEGPGGTATRITGVRAAGAQLVIATDGEPGRLEILELRDPARLAIDVHGVASAPRAPVKVRGAFSQV
RFGRDSGKVRVVLDASGALPRYEVKRVAGGVAVVTSGASVASAEPARKAAPAPGVEPVVAAAPAAPTADPGLARIADVRF
ASAGGGSRIDIAGKAPFVISRPDARTVVLTLDGAKLPRAMERSLDTTAFHGPVAMVSSFNQPQTGQVRIVATLRGSATDR
IVETRDGLTWTFTEGGDAAEAAAPAMPEQAQAADAKVAGFAAEAPAYASSGAPQARGYSGRRITLDFHDIEIRNLLRLIA
DVSKKNIVVADDVSGKVTVSLRNVPWDQALDLVLRSKGLGKEEMGNVIRIAKFEAIAKEQAAKAEAEKARIPLIPLKVRI
IPVNYARAADVASRVKDVLSERGSVSTDERTNVLIVKDIPEALVRAEGLVRNLDTEIPQVLIESRIVEASSNFNRQLGVQ
WGGNASFTQATGNPTGVAFPNNVSGAGAAGQAPNQGTSSTPNYAVNLPAAIGQGSGGGIGLVLGSANGAFNLNLRLSALE
NNGVVKTISSPKIATIDNKEATIGQGISIPFSQTSASGVNTTFVEAKLELKVTPHVTADGSILLKIKATNNAPNSSLTGS
NGQPSISKREAETEVLVKDGETTVIGGIYTRSTASKTASVPFLSKIPLLGFFFRSDTNTDDHTELLIFITPRILNRQPAT
AAAAASN

Sequences:

>Translated_887_residues
MTSRLKPIVGLLLWGAISAATAAEPNVIRGIEVGQREGALELEIRGSRAPSYSVFKLQDPPRLVVDLAGADVSGVGSPIQ
VGKAGVLAVSTAQYKDERSAVGRVIIALDGARRYDVAPRGDAVVVRVLEAETAGAPAAAAASSPAATAPAAPPASVPAAP
SPSGDGHLVSRRVDEGPGGTATRITGVRAAGAQLVIATDGEPGRLEILELRDPARLAIDVHGVASAPRAPVKVRGAFSQV
RFGRDSGKVRVVLDASGALPRYEVKRVAGGVAVVTSGASVASAEPARKAAPAPGVEPVVAAAPAAPTADPGLARIADVRF
ASAGGGSRIDIAGKAPFVISRPDARTVVLTLDGAKLPRAMERSLDTTAFHGPVAMVSSFNQPQTGQVRIVATLRGSATDR
IVETRDGLTWTFTEGGDAAEAAAPAMPEQAQAADAKVAGFAAEAPAYASSGAPQARGYSGRRITLDFHDIEIRNLLRLIA
DVSKKNIVVADDVSGKVTVSLRNVPWDQALDLVLRSKGLGKEEMGNVIRIAKFEAIAKEQAAKAEAEKARIPLIPLKVRI
IPVNYARAADVASRVKDVLSERGSVSTDERTNVLIVKDIPEALVRAEGLVRNLDTEIPQVLIESRIVEASSNFNRQLGVQ
WGGNASFTQATGNPTGVAFPNNVSGAGAAGQAPNQGTSSTPNYAVNLPAAIGQGSGGGIGLVLGSANGAFNLNLRLSALE
NNGVVKTISSPKIATIDNKEATIGQGISIPFSQTSASGVNTTFVEAKLELKVTPHVTADGSILLKIKATNNAPNSSLTGS
NGQPSISKREAETEVLVKDGETTVIGGIYTRSTASKTASVPFLSKIPLLGFFFRSDTNTDDHTELLIFITPRILNRQPAT
AAAAASN
>Mature_886_residues
TSRLKPIVGLLLWGAISAATAAEPNVIRGIEVGQREGALELEIRGSRAPSYSVFKLQDPPRLVVDLAGADVSGVGSPIQV
GKAGVLAVSTAQYKDERSAVGRVIIALDGARRYDVAPRGDAVVVRVLEAETAGAPAAAAASSPAATAPAAPPASVPAAPS
PSGDGHLVSRRVDEGPGGTATRITGVRAAGAQLVIATDGEPGRLEILELRDPARLAIDVHGVASAPRAPVKVRGAFSQVR
FGRDSGKVRVVLDASGALPRYEVKRVAGGVAVVTSGASVASAEPARKAAPAPGVEPVVAAAPAAPTADPGLARIADVRFA
SAGGGSRIDIAGKAPFVISRPDARTVVLTLDGAKLPRAMERSLDTTAFHGPVAMVSSFNQPQTGQVRIVATLRGSATDRI
VETRDGLTWTFTEGGDAAEAAAPAMPEQAQAADAKVAGFAAEAPAYASSGAPQARGYSGRRITLDFHDIEIRNLLRLIAD
VSKKNIVVADDVSGKVTVSLRNVPWDQALDLVLRSKGLGKEEMGNVIRIAKFEAIAKEQAAKAEAEKARIPLIPLKVRII
PVNYARAADVASRVKDVLSERGSVSTDERTNVLIVKDIPEALVRAEGLVRNLDTEIPQVLIESRIVEASSNFNRQLGVQW
GGNASFTQATGNPTGVAFPNNVSGAGAAGQAPNQGTSSTPNYAVNLPAAIGQGSGGGIGLVLGSANGAFNLNLRLSALEN
NGVVKTISSPKIATIDNKEATIGQGISIPFSQTSASGVNTTFVEAKLELKVTPHVTADGSILLKIKATNNAPNSSLTGSN
GQPSISKREAETEVLVKDGETTVIGGIYTRSTASKTASVPFLSKIPLLGFFFRSDTNTDDHTELLIFITPRILNRQPATA
AAAASN

Specific function: Essential for the formation of pili. Involved in the biogenesis of type 4 fimbriae probably by serving as a "porthole" allowing passage of the fimbrae through the outer membrane [H]

COG id: COG4796

COG function: function code U; Type II secretory pathway, component HofQ

Gene ontology:

Cell location: Cell outer membrane (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GSP D family [H]

Homologues:

Organism=Escherichia coli, GI1789793, Length=419, Percent_Identity=34.8448687350835, Blast_Score=216, Evalue=4e-57,
Organism=Escherichia coli, GI87082242, Length=343, Percent_Identity=29.7376093294461, Blast_Score=107, Evalue=3e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001775
- InterPro:   IPR005644
- InterPro:   IPR013355
- InterPro:   IPR011662
- InterPro:   IPR004846
- InterPro:   IPR004845 [H]

Pfam domain/function: PF00263 Secretin; PF03958 Secretin_N; PF07660 STN [H]

EC number: NA

Molecular weight: Translated: 91443; Mature: 91311

Theoretical pI: Translated: 10.01; Mature: 10.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
0.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
0.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSRLKPIVGLLLWGAISAATAAEPNVIRGIEVGQREGALELEIRGSRAPSYSVFKLQDP
CCCCHHHHHHHHHHHHHHHHCCCCCCEEECEECCCCCCCEEEEEECCCCCCEEEEEECCC
PRLVVDLAGADVSGVGSPIQVGKAGVLAVSTAQYKDERSAVGRVIIALDGARRYDVAPRG
CEEEEEECCCCCCCCCCCCEECCCCEEEEEEHHHCHHHHHHCEEEEEECCCCEECCCCCC
DAVVVRVLEAETAGAPAAAAASSPAATAPAAPPASVPAAPSPSGDGHLVSRRVDEGPGGT
CEEEEEEEECCCCCCCCHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCC
ATRITGVRAAGAQLVIATDGEPGRLEILELRDPARLAIDVHGVASAPRAPVKVRGAFSQV
EEEEEEEEECCCEEEEEECCCCCEEEEEEECCCCEEEEEEECCCCCCCCCEEEECCHHHH
RFGRDSGKVRVVLDASGALPRYEVKRVAGGVAVVTSGASVASAEPARKAAPAPGVEPVVA
EECCCCCCEEEEEECCCCCCHHHHHHHCCCEEEEECCCCCCCCCCHHHCCCCCCCCCCEE
AAPAAPTADPGLARIADVRFASAGGGSRIDIAGKAPFVISRPDARTVVLTLDGAKLPRAM
ECCCCCCCCCCHHHHEEEEEECCCCCCEEEECCCCCEEEECCCCCEEEEEECCCCCCHHH
ERSLDTTAFHGPVAMVSSFNQPQTGQVRIVATLRGSATDRIVETRDGLTWTFTEGGDAAE
HHCCCCCEECCCHHHHHCCCCCCCCCEEEEEEECCCCCCCEEECCCCCEEEEECCCCCHH
AAAPAMPEQAQAADAKVAGFAAEAPAYASSGAPQARGYSGRRITLDFHDIEIRNLLRLIA
HHCCCCCCHHHHCCCEEECEECCCCCCCCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHH
DVSKKNIVVADDVSGKVTVSLRNVPWDQALDLVLRSKGLGKEEMGNVIRIAKFEAIAKEQ
HHCCCCEEEEECCCCEEEEEEECCCHHHHHHHHHHHCCCCHHHHCCEEEEEHHHHHHHHH
AAKAEAEKARIPLIPLKVRIIPVNYARAADVASRVKDVLSERGSVSTDERTNVLIVKDIP
HHHHHHHHCCCCEEEEEEEEEEECCHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCH
EALVRAEGLVRNLDTEIPQVLIESRIVEASSNFNRQLGVQWGGNASFTQATGNPTGVAFP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCEEECCCCCCCEECC
NNVSGAGAAGQAPNQGTSSTPNYAVNLPAAIGQGSGGGIGLVLGSANGAFNLNLRLSALE
CCCCCCCCCCCCCCCCCCCCCCEEEECCCEECCCCCCEEEEEEECCCCEEEEEEEEEEEC
NNGVVKTISSPKIATIDNKEATIGQGISIPFSQTSASGVNTTFVEAKLELKVTPHVTADG
CCCEEEEECCCEEEEECCCCCCCCCCCCCCCCCCCCCCCEEEEEEEEEEEEECCCEECCC
SILLKIKATNNAPNSSLTGSNGQPSISKREAETEVLVKDGETTVIGGIYTRSTASKTASV
EEEEEEEECCCCCCCCCCCCCCCCCCHHCCCCCEEEEECCCEEEEEEEEECCCCCCCCCC
PFLSKIPLLGFFFRSDTNTDDHTELLIFITPRILNRQPATAAAAASN
CCHHCCCEEEEEEECCCCCCCCEEEEEEECCHHHCCCCCCHHHCCCC
>Mature Secondary Structure 
TSRLKPIVGLLLWGAISAATAAEPNVIRGIEVGQREGALELEIRGSRAPSYSVFKLQDP
CCCHHHHHHHHHHHHHHHHCCCCCCEEECEECCCCCCCEEEEEECCCCCCEEEEEECCC
PRLVVDLAGADVSGVGSPIQVGKAGVLAVSTAQYKDERSAVGRVIIALDGARRYDVAPRG
CEEEEEECCCCCCCCCCCCEECCCCEEEEEEHHHCHHHHHHCEEEEEECCCCEECCCCCC
DAVVVRVLEAETAGAPAAAAASSPAATAPAAPPASVPAAPSPSGDGHLVSRRVDEGPGGT
CEEEEEEEECCCCCCCCHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCC
ATRITGVRAAGAQLVIATDGEPGRLEILELRDPARLAIDVHGVASAPRAPVKVRGAFSQV
EEEEEEEEECCCEEEEEECCCCCEEEEEEECCCCEEEEEEECCCCCCCCCEEEECCHHHH
RFGRDSGKVRVVLDASGALPRYEVKRVAGGVAVVTSGASVASAEPARKAAPAPGVEPVVA
EECCCCCCEEEEEECCCCCCHHHHHHHCCCEEEEECCCCCCCCCCHHHCCCCCCCCCCEE
AAPAAPTADPGLARIADVRFASAGGGSRIDIAGKAPFVISRPDARTVVLTLDGAKLPRAM
ECCCCCCCCCCHHHHEEEEEECCCCCCEEEECCCCCEEEECCCCCEEEEEECCCCCCHHH
ERSLDTTAFHGPVAMVSSFNQPQTGQVRIVATLRGSATDRIVETRDGLTWTFTEGGDAAE
HHCCCCCEECCCHHHHHCCCCCCCCCEEEEEEECCCCCCCEEECCCCCEEEEECCCCCHH
AAAPAMPEQAQAADAKVAGFAAEAPAYASSGAPQARGYSGRRITLDFHDIEIRNLLRLIA
HHCCCCCCHHHHCCCEEECEECCCCCCCCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHH
DVSKKNIVVADDVSGKVTVSLRNVPWDQALDLVLRSKGLGKEEMGNVIRIAKFEAIAKEQ
HHCCCCEEEEECCCCEEEEEEECCCHHHHHHHHHHHCCCCHHHHCCEEEEEHHHHHHHHH
AAKAEAEKARIPLIPLKVRIIPVNYARAADVASRVKDVLSERGSVSTDERTNVLIVKDIP
HHHHHHHHCCCCEEEEEEEEEEECCHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCH
EALVRAEGLVRNLDTEIPQVLIESRIVEASSNFNRQLGVQWGGNASFTQATGNPTGVAFP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCEEECCCCCCCEECC
NNVSGAGAAGQAPNQGTSSTPNYAVNLPAAIGQGSGGGIGLVLGSANGAFNLNLRLSALE
CCCCCCCCCCCCCCCCCCCCCCEEEECCCEECCCCCCEEEEEEECCCCEEEEEEEEEEEC
NNGVVKTISSPKIATIDNKEATIGQGISIPFSQTSASGVNTTFVEAKLELKVTPHVTADG
CCCEEEEECCCEEEEECCCCCCCCCCCCCCCCCCCCCCCEEEEEEEEEEEEECCCEECCC
SILLKIKATNNAPNSSLTGSNGQPSISKREAETEVLVKDGETTVIGGIYTRSTASKTASV
EEEEEEEECCCCCCCCCCCCCCCCCCHHCCCCCEEEEECCCEEEEEEEEECCCCCCCCCC
PFLSKIPLLGFFFRSDTNTDDHTELLIFITPRILNRQPATAAAAASN
CCHHCCCEEEEEEECCCCCCCCEEEEEEECCHHHCCCCCCHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7901733; 10984043 [H]