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The map label for this gene is frzF [H]

Identifier: 220915759

GI number: 220915759

Start: 715540

End: 717042

Strand: Direct

Name: frzF [H]

Synonym: A2cp1_0640

Alternate gene names: 220915759

Gene position: 715540-717042 (Clockwise)

Preceding gene: 220915758

Following gene: 220915760

Centisome position: 14.23

GC content: 76.38

Gene sequence:

>1503_bases
GTGAAGCCGATCGCGTCCGAGCACCTGCTGGAGCTGGCCGCGCTGCTCAAGGAGCGGGTCGGGCTCCACGTGCGCCGCGA
GGGCCACTCCGCGCTGCGCATCGCGGTGGCGGCGCGCCTCGAGGGCCTGGCCGCGGTCGCGGACTCCGGCGCGTACCTGG
CGCTGCTCCGCTCCGGCGCCGGCGACGAGGAGCTGCGGCGCCTGCTCCCGCTCGTCACGGTGGGCAAGACCAGCTTCTTC
CGCGACGAGCGGCAGTTCCGGGCGCTCGACGCGATCCTGCCGGGTCTGCTCGAGCGCGCGCGCTCCGGCGGGCGGCGCGT
GGCCATCTGGTCGGCCGGCTGCGCCACCGGCGAGGAGCCGTACTCGATCGCCATGGCCGCCGCCGACGCCGGGGCGGGCC
CGGACGACGTCGAGATCCTCGCCACCGACGTGAACCCCGAGGCGGTCGCGTTCGCCGCGCGCGGCGCCTACGACCCGCGG
CGCGTGCGCGAGATCCCCGCGCACTACCTCGGCCGGCACTTCGATCGCGACGGCGACGCGTTCCACGTGCGCTCCGGCCT
CCGGCGGTACCTGCGCGCCATCCGCCCGCACAACCTGGTGTCGTCCGCGTTCCCGCGCCCGGCCGAGGGCGGCTGGGACG
TCGTGTTCTGCCGGAACGTCATCATCTACTTCGACACGCCCACCACGCAGGCGGTGCTGGCGCAGTTCCACGAGGCGCTC
GCGCCGGGCGGGTACCTGTTCCTCGGCTACTCGGAGTCGCTGTTCCGGCTGTTCGACGGCTTCGAGCTCACCGAGGTCTC
CGGCGCGTTCCTGTACCGCCGCCCCGAGGCGCCCACCCGCGCCGGCCCGTCCGCCCCGCTCGCGCCGCCGTCCCGCCCGC
ACCTGGTGCAGATGCCGGCGGCGCCGCCGCCAGTGCGCCACCTCTCGCTGGTGCCGCCGCCCGCCGCGCGTCCCTCCGCG
CCCGCGCCGGACCCCGAGCCGCTGCCCCTCGCGCCGCAGGAGTACCTCGACGCCGCGGTGGCGCTGTTCGCCGACGGCCG
CTTCGGCGCCGCGCGCGAGCTGCTGGAGCGGCTGCTGGAGAAGGGCGGCGACGACCTGGCCGCGCGGCTCACGCTCGCGA
ACCTGTACGGCGTGCTGCGCCAGCCCGACCGCGCCCGCGCCAGCTACCAGGCCGCGCTGGCGCTCGAGCCGCTCAGCGCC
GAGGCGCACCTGTTCTACGGCATCCACCTGCTCTCGGGCGGCGACGCCGAGGAGGCCGCGCTGGAGCTCGCGCGCGCGCT
GTTCCTCGACCCCGATCTCGCGCTCGGCCACTACTACCTGGGCCGCTGCCGCGAGGCACAGCGCGACGTGGTCCGCGCCC
GGCTGGCGTACCGCAACGCGCTGGAGGCGTACCGCCGCCGGCCGGACGGACGGGCGCAGGCGTTCCTGGGGTACTATCCG
GACATCCCCGAGGACGGCAGCGCGTTTGCGCGCGCGGCCGAGTACGCGCTCGCCGCCTTGTAG

Upstream 100 bases:

>100_bases
GCGCGGTGTTCGGGATGGCGCGCGCCGCGGTGGAGCTCGGGGCGGTGGACCGGGTGCTGCCGGTGGACGAGATCCCGCGC
GCGCTCCGGGAGCTGACGCG

Downstream 100 bases:

>100_bases
GGCGGCCCGGAGCTCCCGGCGGGAGGCGAATCGACATGGCCGAGAAGAAGCGCATCCTCCTGCTCGACGACTCGGCGATC
ACGCTCGAGATGGAGAAGGC

Product: chemotaxis protein CheR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 500; Mature: 500

Protein sequence:

>500_residues
MKPIASEHLLELAALLKERVGLHVRREGHSALRIAVAARLEGLAAVADSGAYLALLRSGAGDEELRRLLPLVTVGKTSFF
RDERQFRALDAILPGLLERARSGGRRVAIWSAGCATGEEPYSIAMAAADAGAGPDDVEILATDVNPEAVAFAARGAYDPR
RVREIPAHYLGRHFDRDGDAFHVRSGLRRYLRAIRPHNLVSSAFPRPAEGGWDVVFCRNVIIYFDTPTTQAVLAQFHEAL
APGGYLFLGYSESLFRLFDGFELTEVSGAFLYRRPEAPTRAGPSAPLAPPSRPHLVQMPAAPPPVRHLSLVPPPAARPSA
PAPDPEPLPLAPQEYLDAAVALFADGRFGAARELLERLLEKGGDDLAARLTLANLYGVLRQPDRARASYQAALALEPLSA
EAHLFYGIHLLSGGDAEEAALELARALFLDPDLALGHYYLGRCREAQRDVVRARLAYRNALEAYRRRPDGRAQAFLGYYP
DIPEDGSAFARAAEYALAAL

Sequences:

>Translated_500_residues
MKPIASEHLLELAALLKERVGLHVRREGHSALRIAVAARLEGLAAVADSGAYLALLRSGAGDEELRRLLPLVTVGKTSFF
RDERQFRALDAILPGLLERARSGGRRVAIWSAGCATGEEPYSIAMAAADAGAGPDDVEILATDVNPEAVAFAARGAYDPR
RVREIPAHYLGRHFDRDGDAFHVRSGLRRYLRAIRPHNLVSSAFPRPAEGGWDVVFCRNVIIYFDTPTTQAVLAQFHEAL
APGGYLFLGYSESLFRLFDGFELTEVSGAFLYRRPEAPTRAGPSAPLAPPSRPHLVQMPAAPPPVRHLSLVPPPAARPSA
PAPDPEPLPLAPQEYLDAAVALFADGRFGAARELLERLLEKGGDDLAARLTLANLYGVLRQPDRARASYQAALALEPLSA
EAHLFYGIHLLSGGDAEEAALELARALFLDPDLALGHYYLGRCREAQRDVVRARLAYRNALEAYRRRPDGRAQAFLGYYP
DIPEDGSAFARAAEYALAAL
>Mature_500_residues
MKPIASEHLLELAALLKERVGLHVRREGHSALRIAVAARLEGLAAVADSGAYLALLRSGAGDEELRRLLPLVTVGKTSFF
RDERQFRALDAILPGLLERARSGGRRVAIWSAGCATGEEPYSIAMAAADAGAGPDDVEILATDVNPEAVAFAARGAYDPR
RVREIPAHYLGRHFDRDGDAFHVRSGLRRYLRAIRPHNLVSSAFPRPAEGGWDVVFCRNVIIYFDTPTTQAVLAQFHEAL
APGGYLFLGYSESLFRLFDGFELTEVSGAFLYRRPEAPTRAGPSAPLAPPSRPHLVQMPAAPPPVRHLSLVPPPAARPSA
PAPDPEPLPLAPQEYLDAAVALFADGRFGAARELLERLLEKGGDDLAARLTLANLYGVLRQPDRARASYQAALALEPLSA
EAHLFYGIHLLSGGDAEEAALELARALFLDPDLALGHYYLGRCREAQRDVVRARLAYRNALEAYRRRPDGRAQAFLGYYP
DIPEDGSAFARAAEYALAAL

Specific function: This methyltransferase is one of the proteins required for the normal aggregation of M.xanthus cells during fruiting body formation. It is also a component of a sensory transduction pathway that controls the frequency at which cells reverse their gliding

COG id: COG1352

COG function: function code NT; Methylase of chemotaxis methyl-accepting proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 3 TPR repeats [H]

Homologues:

Organism=Escherichia coli, GI1788193, Length=266, Percent_Identity=33.0827067669173, Blast_Score=125, Evalue=6e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022642
- InterPro:   IPR000780
- InterPro:   IPR022641
- InterPro:   IPR013026
- InterPro:   IPR011990
- InterPro:   IPR019734 [H]

Pfam domain/function: PF01739 CheR; PF03705 CheR_N [H]

EC number: =2.1.1.80 [H]

Molecular weight: Translated: 54336; Mature: 54336

Theoretical pI: Translated: 6.85; Mature: 6.85

Prosite motif: PS50005 TPR L=RR ; PS50293 TPR_REGION ; PS50123 CHER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKPIASEHLLELAALLKERVGLHVRREGHSALRIAVAARLEGLAAVADSGAYLALLRSGA
CCCCHHHHHHHHHHHHHHHHCCEEEECCCHHHHHHHHHHHHHHHHHHCCCCEEEEECCCC
GDEELRRLLPLVTVGKTSFFRDERQFRALDAILPGLLERARSGGRRVAIWSAGCATGEEP
CHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCC
YSIAMAAADAGAGPDDVEILATDVNPEAVAFAARGAYDPRRVREIPAHYLGRHFDRDGDA
CEEEEEECCCCCCCCCCEEEEECCCCHHEEEECCCCCCHHHHHHCCHHHHHHHCCCCCCC
FHVRSGLRRYLRAIRPHNLVSSAFPRPAEGGWDVVFCRNVIIYFDTPTTQAVLAQFHEAL
HHHHHHHHHHHHHHCCCHHHHHCCCCCCCCCCCEEEECCEEEEECCCCHHHHHHHHHHHH
APGGYLFLGYSESLFRLFDGFELTEVSGAFLYRRPEAPTRAGPSAPLAPPSRPHLVQMPA
CCCCEEEECCCHHHHHHHCCCCEEECCCEEEEECCCCCCCCCCCCCCCCCCCCCEEECCC
APPPVRHLSLVPPPAARPSAPAPDPEPLPLAPQEYLDAAVALFADGRFGAARELLERLLE
CCCCCCCEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
KGGDDLAARLTLANLYGVLRQPDRARASYQAALALEPLSAEAHLFYGIHLLSGGDAEEAA
CCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHEEECCCCCCEEEEEEEEEECCCCHHHHH
LELARALFLDPDLALGHYYLGRCREAQRDVVRARLAYRNALEAYRRRPDGRAQAFLGYYP
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHEEECCCC
DIPEDGSAFARAAEYALAAL
CCCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MKPIASEHLLELAALLKERVGLHVRREGHSALRIAVAARLEGLAAVADSGAYLALLRSGA
CCCCHHHHHHHHHHHHHHHHCCEEEECCCHHHHHHHHHHHHHHHHHHCCCCEEEEECCCC
GDEELRRLLPLVTVGKTSFFRDERQFRALDAILPGLLERARSGGRRVAIWSAGCATGEEP
CHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCC
YSIAMAAADAGAGPDDVEILATDVNPEAVAFAARGAYDPRRVREIPAHYLGRHFDRDGDA
CEEEEEECCCCCCCCCCEEEEECCCCHHEEEECCCCCCHHHHHHCCHHHHHHHCCCCCCC
FHVRSGLRRYLRAIRPHNLVSSAFPRPAEGGWDVVFCRNVIIYFDTPTTQAVLAQFHEAL
HHHHHHHHHHHHHHCCCHHHHHCCCCCCCCCCCEEEECCEEEEECCCCHHHHHHHHHHHH
APGGYLFLGYSESLFRLFDGFELTEVSGAFLYRRPEAPTRAGPSAPLAPPSRPHLVQMPA
CCCCEEEECCCHHHHHHHCCCCEEECCCEEEEECCCCCCCCCCCCCCCCCCCCCEEECCC
APPPVRHLSLVPPPAARPSAPAPDPEPLPLAPQEYLDAAVALFADGRFGAARELLERLLE
CCCCCCCEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
KGGDDLAARLTLANLYGVLRQPDRARASYQAALALEPLSAEAHLFYGIHLLSGGDAEEAA
CCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHEEECCCCCCEEEEEEEEEECCCCHHHHH
LELARALFLDPDLALGHYYLGRCREAQRDVVRARLAYRNALEAYRRRPDGRAQAFLGYYP
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHEEECCCC
DIPEDGSAFARAAEYALAAL
CCCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2168368 [H]