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The map label for this gene is algU [H]

Identifier: 220915613

GI number: 220915613

Start: 567688

End: 568374

Strand: Direct

Name: algU [H]

Synonym: A2cp1_0494

Alternate gene names: 220915613

Gene position: 567688-568374 (Clockwise)

Preceding gene: 220915611

Following gene: 220915616

Centisome position: 11.29

GC content: 75.25

Gene sequence:

>687_bases
ATGGCCGTGCAGGCAGGCAGGACCCGCGTCGTGCCCACGCTGGCGCCCGCGGACGACGAGGTGGTGGCGCGGGTGCTCGA
AGGGGACGTGGCGCTCTTCGAGGTGCTCATGCGCCGGCACAACCCGCGGCTGTACCGGGCGATCCGCTCGGTGCTGCGCG
ACGAGGCCGAGGTGGAGGACGCGATGCAGCAGGCGTACCTCCAGGCGTATGCACACCTGGGCGACTTCCAGGGGCAGGCG
GCGTTCTCGACCTGGCTGGTGCGCATCGGCGTGAACGAGGCGCTCATGCGCCTGCGCGGGCGCGGGCGGCTGGTGCTCGC
GGCAGAGCCGCCCGAGGGCGGCAGGGTCGGCGAGGAGGAGCACGTGGCGGATCCGAGCCCCGAGGACCAGGCGGCGACGC
ACGAGGCACGGGCGCTGCTCGAGCAGGCGGTGGACCGGCTGCCGCTGCACCTGCGGACCGTGTACGTGCTCCGCGAGATC
GAGCAGCTCTCCACCGCCGAGGTGGCGGCCGCGCTCGAGCTGGGCGAGGAGGCGGTGAAGGTGCGCCTCCACCGCGCCCG
CCTCGCGCTCCGCGAGCTCATCGCCGCGCGCGTCGGCCAGAGCGCGCCCAAGGCGTTCGGGTTCCTCGCGCCGCGCTGCG
ACCGCGTGGTCGCGGCGGTGCTCGCGGCCATCCCGGCGCGCCGTTGA

Upstream 100 bases:

>100_bases
GTGAACCTCCTGCCCCATCGATGCGGCGGGCGGCGGCGGCGTTACGGCGGTAACGATCCGGCCGCCGGTGCATCGGATGG
ACGAGGGGACTGGAGGCTCC

Downstream 100 bases:

>100_bases
ACGTCCGCGACACCGGGCCGTCCGCTCGCCCTACGACCTGGGCGAGCGGACGACCGTGTTTCCTCAGTAGCCGCCGCCCC
CACCTCCGCCGCCACCACCG

Product: RNA polymerase sigma factor

Products: NA

Alternate protein names: Sigma-30 [H]

Number of amino acids: Translated: 228; Mature: 227

Protein sequence:

>228_residues
MAVQAGRTRVVPTLAPADDEVVARVLEGDVALFEVLMRRHNPRLYRAIRSVLRDEAEVEDAMQQAYLQAYAHLGDFQGQA
AFSTWLVRIGVNEALMRLRGRGRLVLAAEPPEGGRVGEEEHVADPSPEDQAATHEARALLEQAVDRLPLHLRTVYVLREI
EQLSTAEVAAALELGEEAVKVRLHRARLALRELIAARVGQSAPKAFGFLAPRCDRVVAAVLAAIPARR

Sequences:

>Translated_228_residues
MAVQAGRTRVVPTLAPADDEVVARVLEGDVALFEVLMRRHNPRLYRAIRSVLRDEAEVEDAMQQAYLQAYAHLGDFQGQA
AFSTWLVRIGVNEALMRLRGRGRLVLAAEPPEGGRVGEEEHVADPSPEDQAATHEARALLEQAVDRLPLHLRTVYVLREI
EQLSTAEVAAALELGEEAVKVRLHRARLALRELIAARVGQSAPKAFGFLAPRCDRVVAAVLAAIPARR
>Mature_227_residues
AVQAGRTRVVPTLAPADDEVVARVLEGDVALFEVLMRRHNPRLYRAIRSVLRDEAEVEDAMQQAYLQAYAHLGDFQGQAA
FSTWLVRIGVNEALMRLRGRGRLVLAAEPPEGGRVGEEEHVADPSPEDQAATHEARALLEQAVDRLPLHLRTVYVLREIE
QLSTAEVAAALELGEEAVKVRLHRARLALRELIAARVGQSAPKAFGFLAPRCDRVVAAVLAAIPARR

Specific function: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor regulates genes such as algD, involved in alginate biosynthesis [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sigma-70 factor family. ECF subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788926, Length=181, Percent_Identity=32.0441988950276, Blast_Score=83, Evalue=2e-17,

Paralogues:

None

Copy number: <10 [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014284
- InterPro:   IPR000838
- InterPro:   IPR007627
- InterPro:   IPR013249
- InterPro:   IPR014286
- InterPro:   IPR013325
- InterPro:   IPR013324 [H]

Pfam domain/function: PF04542 Sigma70_r2; PF08281 Sigma70_r4_2 [H]

EC number: NA

Molecular weight: Translated: 25082; Mature: 24951

Theoretical pI: Translated: 6.81; Mature: 6.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVQAGRTRVVPTLAPADDEVVARVLEGDVALFEVLMRRHNPRLYRAIRSVLRDEAEVED
CCCCCCCCCCCCCCCCCCHHHHHHHHHCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
AMQQAYLQAYAHLGDFQGQAAFSTWLVRIGVNEALMRLRGRGRLVLAAEPPEGGRVGEEE
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCHH
HVADPSPEDQAATHEARALLEQAVDRLPLHLRTVYVLREIEQLSTAEVAAALELGEEAVK
CCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VRLHRARLALRELIAARVGQSAPKAFGFLAPRCDRVVAAVLAAIPARR
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHCHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
AVQAGRTRVVPTLAPADDEVVARVLEGDVALFEVLMRRHNPRLYRAIRSVLRDEAEVED
CCCCCCCCCCCCCCCCCHHHHHHHHHCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
AMQQAYLQAYAHLGDFQGQAAFSTWLVRIGVNEALMRLRGRGRLVLAAEPPEGGRVGEEE
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCHH
HVADPSPEDQAATHEARALLEQAVDRLPLHLRTVYVLREIEQLSTAEVAAALELGEEAVK
CCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VRLHRARLALRELIAARVGQSAPKAFGFLAPRCDRVVAAVLAAIPARR
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHCHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8432708; 8378309; 7961421; 10984043; 7737518 [H]