Click here to switch to the map view.

The map label for this gene is yqjD [H]

Identifier: 220915610

GI number: 220915610

Start: 562300

End: 564024

Strand: Direct

Name: yqjD [H]

Synonym: A2cp1_0491

Alternate gene names: 220915610

Gene position: 562300-564024 (Clockwise)

Preceding gene: 220915609

Following gene: 220915611

Centisome position: 11.18

GC content: 68.87

Gene sequence:

>1725_bases
GTGACCACGAAGGCGATCATCCCGACCCTGACGAACCCGCTCGATCCGCCCGAGAAGGTGGAGTTCACCATCCCCGGCGA
GATCGCCAGGGCCACCGGCGGCTACGAGGAGGCCATGAAGGAGGGCTGGGAGCTCATCCAGCGTCCCATCCGCTCGGTCC
CGGTCGATCAGATCGAGAAGCAGCACATCAAGAAGCGCATGACGGTGTGGGAGCGGATCCGCGTCCTCTCGGACAAGGAG
CCGATGGTCCTGTACCAGAACTGGGGCAAGAACCTCGACGGCGCCTCGCTCGTCACCGCCGTCCTGAACATCGGCGGCCG
CGACGTCGCGGTGTACGGGCACGACTTCACCGTCCGCGCCGGCTCGATGGACGCGACCAACGGCTCGAAGCTGGCGCGCC
TGTTCCGCATGGCCGGCGAGAAGGGGATCCCGCTCATCGGCATGAACGACTCGGCCGGCGCCTACGTGCCGGCGGGCGTG
GGCGGCCTCGACGGCTACGCCGAGGCGTTCACCGCGCTGCGCCGGATCAGCGGCGTGGTCCCGTCGATCATGTGCATGTT
CGGCTTCAACGCCGGCGGCGGCTCCTACCTGCCGCGCCAGGGCAGCTTCGTGATCCAGCCTGCCGACACGTTCTTCGGCC
TCACCGGCCCGGGCGTGGTGAAGTCGGTGCTGGGCGAGGAGATCTCGCCGGAGGACCTGGGCGGTCCCAAGGTGCACGGC
GCCTCGGGCGTGGCCGACCTCACCGTCATCGACGAGCTCGCCGCGCTCCGCCAGGCGGTGCGCCTGCTGAACTACGTCCC
GGACAACAACCGGACGATGGCGCCGTTCCAGGAGACGAGCGACCCGCTCGATCGCAAGACCTGGGAGATCAACACGCTGC
TGAAGAAGGCGTTCAACTCGCCGACGGGCTTCAACACGCCGTTCGACGTGTCGATCATCATCCAGCAGGTCTGCGACTAC
GGTGACTTCTTCGAGATCCAGCCGGAGCGCGCGCGCGAGGTGGTCACCGCGTTCGGCCGCCTGGGCGGCCACGTGGTCGG
CTTCGTCGCGAACAACAGCGCCATCGGCTCCGGCCAGATCGACTGCGACACCGCGCTGAAGATCGCGAGGTTCGTGCGCT
TCTGCAACGTCTACAACATCCCCATCATCTTCATGGAGGACACCACCGGCTTCCTCCCCGGGCGCGAGCAGGAGGCGCGC
GGCATCGTGCAGGCCGGCCGCTCCATGCTCGACGCGATCGTGGACGTCCGCACGCCGCGCATCCTGCTCATCCTGCGCAA
CGCGTTCGGCGGCGCCTACGCCTCGTACAACAACTACCCGACCGGCGCCGACGTGGTGCTGGCGCTCCCCACCACGCGGC
TCGCGGTGATGGGGCCGGCCGGCAAGGAGTTCGTCTACAAGGACGAGCTCCGCAAGATGCGCAGCGCCGCCGCCGAGCGC
GCCAAGAAGGGCGCGCAGCAGCGCGTGGCCGCGGGCATGGAGGGCGAGGCCGCCCGCAAGGACGCCGAGAAGGAGGCGGC
CGAGTGGCTCAAGGGCGAGGAGGCCGCGCTGGGCCGCCGCTACGAGAAGGAGCTGATGAACCCGAAGGAAGGCCTGGCGC
TCGGGTCGATCTCGTCGCTGGTCATGCCGACCGACCTCCGCAAGGTGCTCGGCCAGAACCTGCACTTCCTGCTCCGCCAC
TACACGCCGTCGCCGATGAGCGGCCCGCAGCGCGAGTTCCACTAG

Upstream 100 bases:

>100_bases
TGGGCGGGGTCCGCGCAGCGCGCTGCTCGATCCGAGCGCGCTGCGGCGGTTCCGCGCAGGGCCGCAGTCGACGCCAGCCA
CCTCCTGGAGGTCCGTGCCC

Downstream 100 bases:

>100_bases
GCCCCGCGCACCGGACCCGAGACCCGGAGAACCGAACGACATGGCTTCCAACGTCGACCACTACCGGAACAACCCGCTCA
TCCACCGCGACCGCCGCCTG

Product: Propionyl-CoA carboxylase

Products: NA

Alternate protein names: PCCase; Propanoyl-CoA:carbon dioxide ligase [H]

Number of amino acids: Translated: 574; Mature: 573

Protein sequence:

>574_residues
MTTKAIIPTLTNPLDPPEKVEFTIPGEIARATGGYEEAMKEGWELIQRPIRSVPVDQIEKQHIKKRMTVWERIRVLSDKE
PMVLYQNWGKNLDGASLVTAVLNIGGRDVAVYGHDFTVRAGSMDATNGSKLARLFRMAGEKGIPLIGMNDSAGAYVPAGV
GGLDGYAEAFTALRRISGVVPSIMCMFGFNAGGGSYLPRQGSFVIQPADTFFGLTGPGVVKSVLGEEISPEDLGGPKVHG
ASGVADLTVIDELAALRQAVRLLNYVPDNNRTMAPFQETSDPLDRKTWEINTLLKKAFNSPTGFNTPFDVSIIIQQVCDY
GDFFEIQPERAREVVTAFGRLGGHVVGFVANNSAIGSGQIDCDTALKIARFVRFCNVYNIPIIFMEDTTGFLPGREQEAR
GIVQAGRSMLDAIVDVRTPRILLILRNAFGGAYASYNNYPTGADVVLALPTTRLAVMGPAGKEFVYKDELRKMRSAAAER
AKKGAQQRVAAGMEGEAARKDAEKEAAEWLKGEEAALGRRYEKELMNPKEGLALGSISSLVMPTDLRKVLGQNLHFLLRH
YTPSPMSGPQREFH

Sequences:

>Translated_574_residues
MTTKAIIPTLTNPLDPPEKVEFTIPGEIARATGGYEEAMKEGWELIQRPIRSVPVDQIEKQHIKKRMTVWERIRVLSDKE
PMVLYQNWGKNLDGASLVTAVLNIGGRDVAVYGHDFTVRAGSMDATNGSKLARLFRMAGEKGIPLIGMNDSAGAYVPAGV
GGLDGYAEAFTALRRISGVVPSIMCMFGFNAGGGSYLPRQGSFVIQPADTFFGLTGPGVVKSVLGEEISPEDLGGPKVHG
ASGVADLTVIDELAALRQAVRLLNYVPDNNRTMAPFQETSDPLDRKTWEINTLLKKAFNSPTGFNTPFDVSIIIQQVCDY
GDFFEIQPERAREVVTAFGRLGGHVVGFVANNSAIGSGQIDCDTALKIARFVRFCNVYNIPIIFMEDTTGFLPGREQEAR
GIVQAGRSMLDAIVDVRTPRILLILRNAFGGAYASYNNYPTGADVVLALPTTRLAVMGPAGKEFVYKDELRKMRSAAAER
AKKGAQQRVAAGMEGEAARKDAEKEAAEWLKGEEAALGRRYEKELMNPKEGLALGSISSLVMPTDLRKVLGQNLHFLLRH
YTPSPMSGPQREFH
>Mature_573_residues
TTKAIIPTLTNPLDPPEKVEFTIPGEIARATGGYEEAMKEGWELIQRPIRSVPVDQIEKQHIKKRMTVWERIRVLSDKEP
MVLYQNWGKNLDGASLVTAVLNIGGRDVAVYGHDFTVRAGSMDATNGSKLARLFRMAGEKGIPLIGMNDSAGAYVPAGVG
GLDGYAEAFTALRRISGVVPSIMCMFGFNAGGGSYLPRQGSFVIQPADTFFGLTGPGVVKSVLGEEISPEDLGGPKVHGA
SGVADLTVIDELAALRQAVRLLNYVPDNNRTMAPFQETSDPLDRKTWEINTLLKKAFNSPTGFNTPFDVSIIIQQVCDYG
DFFEIQPERAREVVTAFGRLGGHVVGFVANNSAIGSGQIDCDTALKIARFVRFCNVYNIPIIFMEDTTGFLPGREQEARG
IVQAGRSMLDAIVDVRTPRILLILRNAFGGAYASYNNYPTGADVVLALPTTRLAVMGPAGKEFVYKDELRKMRSAAAERA
KKGAQQRVAAGMEGEAARKDAEKEAAEWLKGEEAALGRRYEKELMNPKEGLALGSISSLVMPTDLRKVLGQNLHFLLRHY
TPSPMSGPQREFH

Specific function: Unknown

COG id: COG4799

COG function: function code I; Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 carboxyltransferase domain [H]

Homologues:

Organism=Homo sapiens, GI119943100, Length=446, Percent_Identity=36.322869955157, Blast_Score=261, Evalue=1e-69,
Organism=Homo sapiens, GI295821216, Length=466, Percent_Identity=34.7639484978541, Blast_Score=249, Evalue=6e-66,
Organism=Homo sapiens, GI11545863, Length=466, Percent_Identity=28.5407725321888, Blast_Score=156, Evalue=4e-38,
Organism=Homo sapiens, GI134142062, Length=396, Percent_Identity=26.2626262626263, Blast_Score=84, Evalue=4e-16,
Organism=Homo sapiens, GI38679960, Length=316, Percent_Identity=25.9493670886076, Blast_Score=77, Evalue=6e-14,
Organism=Homo sapiens, GI38679974, Length=316, Percent_Identity=25.9493670886076, Blast_Score=76, Evalue=8e-14,
Organism=Homo sapiens, GI38679971, Length=316, Percent_Identity=25.9493670886076, Blast_Score=76, Evalue=8e-14,
Organism=Homo sapiens, GI38679977, Length=316, Percent_Identity=25.9493670886076, Blast_Score=76, Evalue=1e-13,
Organism=Homo sapiens, GI38679967, Length=316, Percent_Identity=25.9493670886076, Blast_Score=76, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI25147362, Length=418, Percent_Identity=37.5598086124402, Blast_Score=274, Evalue=1e-73,
Organism=Caenorhabditis elegans, GI25147359, Length=418, Percent_Identity=37.5598086124402, Blast_Score=273, Evalue=2e-73,
Organism=Caenorhabditis elegans, GI17552936, Length=499, Percent_Identity=25.6513026052104, Blast_Score=142, Evalue=3e-34,
Organism=Caenorhabditis elegans, GI71997163, Length=316, Percent_Identity=23.4177215189873, Blast_Score=72, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI133931226, Length=372, Percent_Identity=23.6559139784946, Blast_Score=66, Evalue=6e-11,
Organism=Saccharomyces cerevisiae, GI6324343, Length=314, Percent_Identity=26.7515923566879, Blast_Score=80, Evalue=6e-16,
Organism=Saccharomyces cerevisiae, GI6323863, Length=318, Percent_Identity=24.8427672955975, Blast_Score=80, Evalue=6e-16,
Organism=Drosophila melanogaster, GI24586065, Length=507, Percent_Identity=26.8244575936884, Blast_Score=155, Evalue=1e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000438
- InterPro:   IPR000022
- InterPro:   IPR011763
- InterPro:   IPR011762 [H]

Pfam domain/function: PF01039 Carboxyl_trans [H]

EC number: =6.4.1.3 [H]

Molecular weight: Translated: 62544; Mature: 62412

Theoretical pI: Translated: 7.57; Mature: 7.57

Prosite motif: PS50980 COA_CT_NTER ; PS50989 COA_CT_CTER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTKAIIPTLTNPLDPPEKVEFTIPGEIARATGGYEEAMKEGWELIQRPIRSVPVDQIEK
CCCCCCCHHHCCCCCCCCCEEEECCCHHHHHCCCHHHHHHHHHHHHHHHHHHCCHHHHHH
QHIKKRMTVWERIRVLSDKEPMVLYQNWGKNLDGASLVTAVLNIGGRDVAVYGHDFTVRA
HHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHHHCCCCEEEEECCCEEEEE
GSMDATNGSKLARLFRMAGEKGIPLIGMNDSAGAYVPAGVGGLDGYAEAFTALRRISGVV
CCCCCCCHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
PSIMCMFGFNAGGGSYLPRQGSFVIQPADTFFGLTGPGVVKSVLGEEISPEDLGGPKVHG
HHHHHHHCCCCCCCCCCCCCCCEEEEECHHHCCCCCHHHHHHHHCCCCCCCCCCCCCCCC
ASGVADLTVIDELAALRQAVRLLNYVPDNNRTMAPFQETSDPLDRKTWEINTLLKKAFNS
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEECCCHHCCCCHHHHHHHHHHHHHHHCCC
PTGFNTPFDVSIIIQQVCDYGDFFEIQPERAREVVTAFGRLGGHVVGFVANNSAIGSGQI
CCCCCCCCHHHHHHHHHHCCCCEEEECHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCC
DCDTALKIARFVRFCNVYNIPIIFMEDTTGFLPGREQEARGIVQAGRSMLDAIVDVRTPR
CHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCE
ILLILRNAFGGAYASYNNYPTGADVVLALPTTRLAVMGPAGKEFVYKDELRKMRSAAAER
EEEEEEHHCCCHHCCCCCCCCCCCEEEEECCCEEEEECCCCCCHHHHHHHHHHHHHHHHH
AKKGAQQRVAAGMEGEAARKDAEKEAAEWLKGEEAALGRRYEKELMNPKEGLALGSISSL
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCHHHCCCCCCHHHH
VMPTDLRKVLGQNLHFLLRHYTPSPMSGPQREFH
HCCHHHHHHHCCCHHHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure 
TTKAIIPTLTNPLDPPEKVEFTIPGEIARATGGYEEAMKEGWELIQRPIRSVPVDQIEK
CCCCCCHHHCCCCCCCCCEEEECCCHHHHHCCCHHHHHHHHHHHHHHHHHHCCHHHHHH
QHIKKRMTVWERIRVLSDKEPMVLYQNWGKNLDGASLVTAVLNIGGRDVAVYGHDFTVRA
HHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHHHCCCCEEEEECCCEEEEE
GSMDATNGSKLARLFRMAGEKGIPLIGMNDSAGAYVPAGVGGLDGYAEAFTALRRISGVV
CCCCCCCHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
PSIMCMFGFNAGGGSYLPRQGSFVIQPADTFFGLTGPGVVKSVLGEEISPEDLGGPKVHG
HHHHHHHCCCCCCCCCCCCCCCEEEEECHHHCCCCCHHHHHHHHCCCCCCCCCCCCCCCC
ASGVADLTVIDELAALRQAVRLLNYVPDNNRTMAPFQETSDPLDRKTWEINTLLKKAFNS
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEECCCHHCCCCHHHHHHHHHHHHHHHCCC
PTGFNTPFDVSIIIQQVCDYGDFFEIQPERAREVVTAFGRLGGHVVGFVANNSAIGSGQI
CCCCCCCCHHHHHHHHHHCCCCEEEECHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCC
DCDTALKIARFVRFCNVYNIPIIFMEDTTGFLPGREQEARGIVQAGRSMLDAIVDVRTPR
CHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCE
ILLILRNAFGGAYASYNNYPTGADVVLALPTTRLAVMGPAGKEFVYKDELRKMRSAAAER
EEEEEEHHCCCHHCCCCCCCCCCCEEEEECCCEEEEECCCCCCHHHHHHHHHHHHHHHHH
AKKGAQQRVAAGMEGEAARKDAEKEAAEWLKGEEAALGRRYEKELMNPKEGLALGSISSL
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCHHHCCCCCCHHHH
VMPTDLRKVLGQNLHFLLRHYTPSPMSGPQREFH
HCCHHHHHHHCCCHHHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377 [H]