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The map label for this gene is dspA [H]

Identifier: 220915558

GI number: 220915558

Start: 497232

End: 498134

Strand: Direct

Name: dspA [H]

Synonym: A2cp1_0439

Alternate gene names: 220915558

Gene position: 497232-498134 (Clockwise)

Preceding gene: 220915556

Following gene: 220915559

Centisome position: 9.89

GC content: 71.1

Gene sequence:

>903_bases
TTGAAGCTCCGCCACGTCCTTCCGCTCATCATCGGCTTCGTCTTCGTGCCCGCCGCGCTCATGCTGACGGTGGGGATCCT
GATCCTCGTCTACGGCTCGGTGGCCCGGGACTACCTGTTCGGCATCCTGATCGTGTCGCTGGTCGGCACCACCATCATCG
GCAGCGCGGCCACGCTGGCGGTGCTGTTCCGCGAGGCCCGGGTCGCGAAGCTGCAGACCGACTTCGTGAACAAGGTGAGC
CACGAGCTCCGCACCCCGCTCACCTCGATCCGCATGTTCGTGGAGACGCTCCAGCTCGGCCGCCTGCAGGACCCGCAGCG
GCAGCGCGAGGCGCTCGAGATCGTCGCCGAGGAGACCGCGCGGCTCTCCGGCCTCATCAACCGCCTGCTCGACTGGGCGC
GGATGGAGTCCGGCCGGCGCGTCTACGAGCTCTCCCGGCAGCCCCTCGGCCCGGTGCTCGACGCCGCGCTGGCGGCGTTC
GAGCCGCAGCTGCTGCACCACCCGGTGCAGCTGGAGCGGGACCTCCCGCCGCGGCTGCCCTCGGTGATGGCGGACCGCTC
GGCGCTGGTCGAGGCGGTGCTGAACCTGCTCAACAACGCGTTCAAGTACACCGGGCCGGACAAGCGGATCCGGCTCTCGG
CCGTGGCGAGCGGGCCCACCGTGACCATCGCGGTGACCGACAACGGGCCCGGGATCCCGCTGCGCGACCAGAAGCACGTG
TTCGACAAGTTCTACCGGGCCTCCGACCCGCTCCGGCGCACGGTGGAGGGCACCGGGCTCGGCCTGGCGATGGTGAAGCA
CATCGTGGTCGGGCACGGCGGCAAGGTGTCGGTGGAGAGCGAGCCCGGGTGCGGCGCGACGTTCCGCATCGCGCTGCCGG
TGGCCGGAGGGGCCCATGGCTGA

Upstream 100 bases:

>100_bases
GGCGACGCCCTCCGCCCGCCCGCTCCCCCGCCAGCCGGGGAGGCCGGAGACGGAGGCGTCGGGCAGGCGGTCGGCTTAAG
ATGCCGCGCCAGAGGGCCCC

Downstream 100 bases:

>100_bases
GCGGATCCTGGTGATCGAGGACGACCCCTCCATCCTGCGGGGCCTGCAGCTCAACCTCGGGATGGAGGGCTACACCGTCC
GGTCCGCGACGGACGGCGAG

Product: histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 300; Mature: 300

Protein sequence:

>300_residues
MKLRHVLPLIIGFVFVPAALMLTVGILILVYGSVARDYLFGILIVSLVGTTIIGSAATLAVLFREARVAKLQTDFVNKVS
HELRTPLTSIRMFVETLQLGRLQDPQRQREALEIVAEETARLSGLINRLLDWARMESGRRVYELSRQPLGPVLDAALAAF
EPQLLHHPVQLERDLPPRLPSVMADRSALVEAVLNLLNNAFKYTGPDKRIRLSAVASGPTVTIAVTDNGPGIPLRDQKHV
FDKFYRASDPLRRTVEGTGLGLAMVKHIVVGHGGKVSVESEPGCGATFRIALPVAGGAHG

Sequences:

>Translated_300_residues
MKLRHVLPLIIGFVFVPAALMLTVGILILVYGSVARDYLFGILIVSLVGTTIIGSAATLAVLFREARVAKLQTDFVNKVS
HELRTPLTSIRMFVETLQLGRLQDPQRQREALEIVAEETARLSGLINRLLDWARMESGRRVYELSRQPLGPVLDAALAAF
EPQLLHHPVQLERDLPPRLPSVMADRSALVEAVLNLLNNAFKYTGPDKRIRLSAVASGPTVTIAVTDNGPGIPLRDQKHV
FDKFYRASDPLRRTVEGTGLGLAMVKHIVVGHGGKVSVESEPGCGATFRIALPVAGGAHG
>Mature_300_residues
MKLRHVLPLIIGFVFVPAALMLTVGILILVYGSVARDYLFGILIVSLVGTTIIGSAATLAVLFREARVAKLQTDFVNKVS
HELRTPLTSIRMFVETLQLGRLQDPQRQREALEIVAEETARLSGLINRLLDWARMESGRRVYELSRQPLGPVLDAALAAF
EPQLLHHPVQLERDLPPRLPSVMADRSALVEAVLNLLNNAFKYTGPDKRIRLSAVASGPTVTIAVTDNGPGIPLRDQKHV
FDKFYRASDPLRRTVEGTGLGLAMVKHIVVGHGGKVSVESEPGCGATFRIALPVAGGAHG

Specific function: Member Of The Two-Component Regulatory System Kdpd/Kdpe Involved In The Regulation Of The Kdp Operon. Kdpd May Function As A Membrane-Associated Protein Kinase That Phosphorylates Kdpe In Response To Environmental Signals. [C]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1786912, Length=242, Percent_Identity=35.5371900826446, Blast_Score=113, Evalue=2e-26,
Organism=Escherichia coli, GI1788549, Length=234, Percent_Identity=32.4786324786325, Blast_Score=106, Evalue=2e-24,
Organism=Escherichia coli, GI1788393, Length=226, Percent_Identity=30.0884955752212, Blast_Score=105, Evalue=3e-24,
Organism=Escherichia coli, GI145693157, Length=234, Percent_Identity=29.9145299145299, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI1789149, Length=230, Percent_Identity=30.4347826086957, Blast_Score=102, Evalue=4e-23,
Organism=Escherichia coli, GI1790346, Length=233, Percent_Identity=31.7596566523605, Blast_Score=95, Evalue=6e-21,
Organism=Escherichia coli, GI1790436, Length=220, Percent_Identity=31.3636363636364, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1788713, Length=238, Percent_Identity=30.2521008403361, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI1786600, Length=222, Percent_Identity=31.5315315315315, Blast_Score=92, Evalue=4e-20,
Organism=Escherichia coli, GI87082128, Length=243, Percent_Identity=28.8065843621399, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI48994928, Length=239, Percent_Identity=29.7071129707113, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI1787894, Length=229, Percent_Identity=29.6943231441048, Blast_Score=87, Evalue=9e-19,
Organism=Escherichia coli, GI1786783, Length=222, Percent_Identity=29.7297297297297, Blast_Score=81, Evalue=8e-17,
Organism=Escherichia coli, GI87081816, Length=247, Percent_Identity=28.3400809716599, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1789808, Length=230, Percent_Identity=30, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1787374, Length=212, Percent_Identity=29.7169811320755, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI1790861, Length=218, Percent_Identity=30.2752293577982, Blast_Score=75, Evalue=6e-15,
Organism=Escherichia coli, GI1790300, Length=240, Percent_Identity=30.4166666666667, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1789403, Length=253, Percent_Identity=26.4822134387352, Blast_Score=70, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 32637; Mature: 32637

Theoretical pI: Translated: 10.25; Mature: 10.25

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLRHVLPLIIGFVFVPAALMLTVGILILVYGSVARDYLFGILIVSLVGTTIIGSAATLA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VLFREARVAKLQTDFVNKVSHELRTPLTSIRMFVETLQLGRLQDPQRQREALEIVAEETA
HHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
RLSGLINRLLDWARMESGRRVYELSRQPLGPVLDAALAAFEPQLLHHPVQLERDLPPRLP
HHHHHHHHHHHHHHHHCCCHHHHHHCCCCCHHHHHHHHHHCHHHHCCCHHHCCCCCCCCH
SVMADRSALVEAVLNLLNNAFKYTGPDKRIRLSAVASGPTVTIAVTDNGPGIPLRDQKHV
HHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCEEEEEEECCCCCCCCCCHHHH
FDKFYRASDPLRRTVEGTGLGLAMVKHIVVGHGGKVSVESEPGCGATFRIALPVAGGAHG
HHHHHHCCCHHHHHHCCCCHHHHHHHHHHHCCCCEEEECCCCCCCEEEEEEEECCCCCCC
>Mature Secondary Structure
MKLRHVLPLIIGFVFVPAALMLTVGILILVYGSVARDYLFGILIVSLVGTTIIGSAATLA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VLFREARVAKLQTDFVNKVSHELRTPLTSIRMFVETLQLGRLQDPQRQREALEIVAEETA
HHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
RLSGLINRLLDWARMESGRRVYELSRQPLGPVLDAALAAFEPQLLHHPVQLERDLPPRLP
HHHHHHHHHHHHHHHHCCCHHHHHHCCCCCHHHHHHHHHHCHHHHCCCHHHCCCCCCCCH
SVMADRSALVEAVLNLLNNAFKYTGPDKRIRLSAVASGPTVTIAVTDNGPGIPLRDQKHV
HHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCEEEEEEECCCCCCCCCCHHHH
FDKFYRASDPLRRTVEGTGLGLAMVKHIVVGHGGKVSVESEPGCGATFRIALPVAGGAHG
HHHHHHCCCHHHHHHCCCCHHHHHHHHHHHCCCCEEEECCCCCCCEEEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8535519; 8905231; 3141423 [H]