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The map label for this gene is gcdC [H]

Identifier: 220915401

GI number: 220915401

Start: 314597

End: 315109

Strand: Direct

Name: gcdC [H]

Synonym: A2cp1_0280

Alternate gene names: 220915401

Gene position: 314597-315109 (Clockwise)

Preceding gene: 220915400

Following gene: 220915402

Centisome position: 6.26

GC content: 72.32

Gene sequence:

>513_bases
ATGAAGACCTACGTGGCGCTGCTCGACGGGGGCAAGCGCGAGGTGACGCTCGGGGTGACGCGGCTCGCCACCGGGCAGTA
CGAGGTGCGCATCGGCGACGAGGTGCACCGCGTGGACGCGTACCCGCACGACTACGGGACGCTGTCGCTGCTGGTGGACA
CCCGCAGCTACTCGGCCATGCTCGACGAGCGCGGGGCGAAGGTGCACGTGCAGGTGGACGGCTCGGTGTTCCCGCTCGAG
CTGCTCGACGAGCGGAAGCTGCGCATGCGCCGGGCCTCGCCGCGCGCGAGCGTGGAGGGCCGGCGGGCGGTGACCGCGCC
CATGCCGGGGCGGGTGGTGAAGGTGCTGGTGGCGCCGGGCGACGCGGTGCGGGCCGGCCAGCCGCTGGTGGTCGTCGAGG
CGATGAAGATGGAGAACGAGATGAGGAGCCCGAAGGACGGCAAGGTGGTCGAGGTTCGCGTCGTCGAGGGCCAGGCGGTC
GAGGGCAGCGCGTTGCTCTGCGCGGTGGAGTAG

Upstream 100 bases:

>100_bases
GCGACGCGGCCGAGGCGCACGCGGCCCGGGCCGGGCAGGGGGCGGCGCGCTCCGGCTGGGCGCGCGCCGGCCGGCTGCGG
GCGCTGCGCGGGGGCGGGCG

Downstream 100 bases:

>100_bases
CGGCGCCGCGCCTCCCACTCCCAACCGGCGCCCCCCGTGACGGGCGCGCCGTGCTCCACCCACGGTGAACACATGGCGGA
CGAGAAGAAGCAGCGGTGGC

Product: biotin/lipoyl attachment domain-containing protein

Products: NA

Alternate protein names: Biotin carrier [H]

Number of amino acids: Translated: 170; Mature: 170

Protein sequence:

>170_residues
MKTYVALLDGGKREVTLGVTRLATGQYEVRIGDEVHRVDAYPHDYGTLSLLVDTRSYSAMLDERGAKVHVQVDGSVFPLE
LLDERKLRMRRASPRASVEGRRAVTAPMPGRVVKVLVAPGDAVRAGQPLVVVEAMKMENEMRSPKDGKVVEVRVVEGQAV
EGSALLCAVE

Sequences:

>Translated_170_residues
MKTYVALLDGGKREVTLGVTRLATGQYEVRIGDEVHRVDAYPHDYGTLSLLVDTRSYSAMLDERGAKVHVQVDGSVFPLE
LLDERKLRMRRASPRASVEGRRAVTAPMPGRVVKVLVAPGDAVRAGQPLVVVEAMKMENEMRSPKDGKVVEVRVVEGQAV
EGSALLCAVE
>Mature_170_residues
MKTYVALLDGGKREVTLGVTRLATGQYEVRIGDEVHRVDAYPHDYGTLSLLVDTRSYSAMLDERGAKVHVQVDGSVFPLE
LLDERKLRMRRASPRASVEGRRAVTAPMPGRVVKVLVAPGDAVRAGQPLVVVEAMKMENEMRSPKDGKVVEVRVVEGQAV
EGSALLCAVE

Specific function: Biotin carrier subunit of the primary sodium pump glutaconyl-CoA decarboxylase (GCD) [H]

COG id: COG0511

COG function: function code I; Biotin carboxyl carrier protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 biotinyl-binding domain [H]

Homologues:

Organism=Homo sapiens, GI65506442, Length=126, Percent_Identity=35.7142857142857, Blast_Score=66, Evalue=2e-11,
Organism=Homo sapiens, GI189095269, Length=126, Percent_Identity=35.7142857142857, Blast_Score=66, Evalue=2e-11,
Organism=Homo sapiens, GI106049528, Length=104, Percent_Identity=32.6923076923077, Blast_Score=64, Evalue=4e-11,
Organism=Homo sapiens, GI106049295, Length=104, Percent_Identity=32.6923076923077, Blast_Score=64, Evalue=4e-11,
Organism=Homo sapiens, GI106049292, Length=104, Percent_Identity=32.6923076923077, Blast_Score=64, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17567343, Length=114, Percent_Identity=34.2105263157895, Blast_Score=65, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6319695, Length=104, Percent_Identity=32.6923076923077, Blast_Score=65, Evalue=6e-12,
Organism=Drosophila melanogaster, GI24652212, Length=123, Percent_Identity=34.9593495934959, Blast_Score=73, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24652210, Length=123, Percent_Identity=34.9593495934959, Blast_Score=73, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24652214, Length=123, Percent_Identity=34.9593495934959, Blast_Score=73, Evalue=1e-13,
Organism=Drosophila melanogaster, GI19921944, Length=123, Percent_Identity=34.9593495934959, Blast_Score=73, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24652216, Length=123, Percent_Identity=34.9593495934959, Blast_Score=73, Evalue=1e-13,
Organism=Drosophila melanogaster, GI281363050, Length=123, Percent_Identity=34.9593495934959, Blast_Score=73, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24652224, Length=123, Percent_Identity=34.9593495934959, Blast_Score=73, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24652222, Length=123, Percent_Identity=34.9593495934959, Blast_Score=73, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24652220, Length=123, Percent_Identity=34.9593495934959, Blast_Score=73, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24652218, Length=123, Percent_Identity=34.9593495934959, Blast_Score=73, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001882
- InterPro:   IPR000089
- InterPro:   IPR011053 [H]

Pfam domain/function: PF00364 Biotin_lipoyl [H]

EC number: =4.1.1.70 [H]

Molecular weight: Translated: 18554; Mature: 18554

Theoretical pI: Translated: 8.45; Mature: 8.45

Prosite motif: PS50968 BIOTINYL_LIPOYL ; PS00188 BIOTIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTYVALLDGGKREVTLGVTRLATGQYEVRIGDEVHRVDAYPHDYGTLSLLVDTRSYSAM
CCEEEEEECCCCEEEEEEEEEEECCEEEEEECCEEEEEECCCCCCCEEEEEEECCCHHHH
LDERGAKVHVQVDGSVFPLELLDERKLRMRRASPRASVEGRRAVTAPMPGRVVKVLVAPG
HHCCCCEEEEEECCCEEEHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCCEEEEEEECCC
DAVRAGQPLVVVEAMKMENEMRSPKDGKVVEVRVVEGQAVEGSALLCAVE
CCCCCCCCEEEEEEEHHHHHHCCCCCCCEEEEEEECCCEECCCEEEEEEC
>Mature Secondary Structure
MKTYVALLDGGKREVTLGVTRLATGQYEVRIGDEVHRVDAYPHDYGTLSLLVDTRSYSAM
CCEEEEEECCCCEEEEEEEEEEECCEEEEEECCEEEEEECCCCCCCEEEEEEECCCHHHH
LDERGAKVHVQVDGSVFPLELLDERKLRMRRASPRASVEGRRAVTAPMPGRVVKVLVAPG
HHCCCCEEEEEECCCEEEHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCCEEEEEEECCC
DAVRAGQPLVVVEAMKMENEMRSPKDGKVVEVRVVEGQAVEGSALLCAVE
CCCCCCCCEEEEEEEHHHHHHCCCCCCCEEEEEEECCCEECCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10027965 [H]