Click here to switch to the map view.

The map label for this gene is plsC [H]

Identifier: 220915397

GI number: 220915397

Start: 310327

End: 311061

Strand: Direct

Name: plsC [H]

Synonym: A2cp1_0276

Alternate gene names: 220915397

Gene position: 310327-311061 (Clockwise)

Preceding gene: 220915396

Following gene: 220915398

Centisome position: 6.17

GC content: 71.43

Gene sequence:

>735_bases
ATGCTGGCCGTCTTCTCCTTCGTCTACTGGATCTTCTTCGTCCTCACGCTCCCGTTCCTGTTCGCGGTGGCGCTCGTCGT
GTTCGTGCTCACCGCGCCGTTCGACCCGCGCCGGGTGGCGCTCCAGCTCTGGTCGTGCGCCTGGGCGTCGTTCTACGTCG
TGGTGAACCCGCTCTGGCGCTCGCGCGTCGTCGGCCGCGAGAAGCTGCCGTGGAACGGCGCCGCGGTGCTGGTCGCGAAC
CACCTCTCCATGCTCGACATCCTGGTGCTGTACGGCGTCTTCCGGCCGTTCAAGTGGGTGTCGAAGGCGGAGCTGTTCCG
CGTGCCGTTCGTGGGCTGGAACATGTGGCTGAACGACTGCGTGCCGGTCTGGCGCGGCGACCGCGAGTCGGTGCGGAAGA
TGATGGCCCACTGCCGCGCCCACCTCGCGCGCGGCGCGCCGGTGATGATCTTCCCCGAGGGCACGCGCTCGCCGGACGGG
CGGCTGCAGGCGTTCAAGGACGGCGCGTTCCGGCTGGCCGTGGACGCGAACGTCCCGGTCATCCCCATCGCCGTGAGCGG
CACCTCCGAGGCGCTGCCCAAGCACGGGATGGTGCTCCGCCAGCGCATGCGCGCCGAGGTGCACGTGCTCGATCCCATCC
ACCCCTCCGCGTTCGACGGCCCGGCCGCGCTCCGCGAGGCGGTCCGGGACGCCATCGCCGCGGCGCTGCCGCCGGAGCAC
CGGCCTGGCGCGTAG

Upstream 100 bases:

>100_bases
GGCGCGGCTGCGCCGCGCGCTGCCTCACCTGTGCCGCGCTCGTGTCGCCGCCCAGCACACCCTTGCGGGATGGCCGGTCC
GGGGCGAGGATGCGCCCGCG

Downstream 100 bases:

>100_bases
GTCCCGCGCAGGTCCTGGACGACGCCGCCCGGCCCGCACCCCGCGCAGGCGCTGCCCGCGCGCGATCCCCGCTGCATGTT
GCCGGGATGATCACGCACAC

Product: 1-acyl-sn-glycerol-3-phosphate acyltransferase

Products: NA

Alternate protein names: 1-AGP acyltransferase; 1-AGPAT; Lysophosphatidic acid acyltransferase; LPAAT; Phosphatidic acid synthase; PA synthase [H]

Number of amino acids: Translated: 244; Mature: 244

Protein sequence:

>244_residues
MLAVFSFVYWIFFVLTLPFLFAVALVVFVLTAPFDPRRVALQLWSCAWASFYVVVNPLWRSRVVGREKLPWNGAAVLVAN
HLSMLDILVLYGVFRPFKWVSKAELFRVPFVGWNMWLNDCVPVWRGDRESVRKMMAHCRAHLARGAPVMIFPEGTRSPDG
RLQAFKDGAFRLAVDANVPVIPIAVSGTSEALPKHGMVLRQRMRAEVHVLDPIHPSAFDGPAALREAVRDAIAAALPPEH
RPGA

Sequences:

>Translated_244_residues
MLAVFSFVYWIFFVLTLPFLFAVALVVFVLTAPFDPRRVALQLWSCAWASFYVVVNPLWRSRVVGREKLPWNGAAVLVAN
HLSMLDILVLYGVFRPFKWVSKAELFRVPFVGWNMWLNDCVPVWRGDRESVRKMMAHCRAHLARGAPVMIFPEGTRSPDG
RLQAFKDGAFRLAVDANVPVIPIAVSGTSEALPKHGMVLRQRMRAEVHVLDPIHPSAFDGPAALREAVRDAIAAALPPEH
RPGA
>Mature_244_residues
MLAVFSFVYWIFFVLTLPFLFAVALVVFVLTAPFDPRRVALQLWSCAWASFYVVVNPLWRSRVVGREKLPWNGAAVLVAN
HLSMLDILVLYGVFRPFKWVSKAELFRVPFVGWNMWLNDCVPVWRGDRESVRKMMAHCRAHLARGAPVMIFPEGTRSPDG
RLQAFKDGAFRLAVDANVPVIPIAVSGTSEALPKHGMVLRQRMRAEVHVLDPIHPSAFDGPAALREAVRDAIAAALPPEH
RPGA

Specific function: Converts lysophosphatidic acid (LPA) into phosphatidic acid by incorporating an acyl moiety at the 2 position. This enzyme can utilize either acyl-CoA or acyl-ACP as the fatty acyl donor [H]

COG id: COG0204

COG function: function code I; 1-acyl-sn-glycerol-3-phosphate acyltransferase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI5453718, Length=180, Percent_Identity=33.3333333333333, Blast_Score=66, Evalue=3e-11,
Organism=Homo sapiens, GI15100175, Length=180, Percent_Identity=33.3333333333333, Blast_Score=66, Evalue=3e-11,
Organism=Escherichia coli, GI1789395, Length=234, Percent_Identity=28.6324786324786, Blast_Score=79, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17564032, Length=179, Percent_Identity=30.7262569832402, Blast_Score=86, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6320151, Length=182, Percent_Identity=34.6153846153846, Blast_Score=85, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24641614, Length=236, Percent_Identity=27.1186440677966, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24641612, Length=236, Percent_Identity=27.1186440677966, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI281364648, Length=183, Percent_Identity=28.4153005464481, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24582856, Length=183, Percent_Identity=28.4153005464481, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24582854, Length=183, Percent_Identity=28.4153005464481, Blast_Score=70, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002123
- InterPro:   IPR004552 [H]

Pfam domain/function: PF01553 Acyltransferase [H]

EC number: =2.3.1.51 [H]

Molecular weight: Translated: 27350; Mature: 27350

Theoretical pI: Translated: 10.63; Mature: 10.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLAVFSFVYWIFFVLTLPFLFAVALVVFVLTAPFDPRRVALQLWSCAWASFYVVVNPLWR
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCHHHH
SRVVGREKLPWNGAAVLVANHLSMLDILVLYGVFRPFKWVSKAELFRVPFVGWNMWLNDC
HHHCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHC
VPVWRGDRESVRKMMAHCRAHLARGAPVMIFPEGTRSPDGRLQAFKDGAFRLAVDANVPV
HHHCCCCHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHCCCCCEEEEEECCCCE
IPIAVSGTSEALPKHGMVLRQRMRAEVHVLDPIHPSAFDGPAALREAVRDAIAAALPPEH
EEEEECCCHHHCCHHHHHHHHHHHHHEEEECCCCCCCCCCHHHHHHHHHHHHHHHCCCCC
RPGA
CCCC
>Mature Secondary Structure
MLAVFSFVYWIFFVLTLPFLFAVALVVFVLTAPFDPRRVALQLWSCAWASFYVVVNPLWR
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCHHHH
SRVVGREKLPWNGAAVLVANHLSMLDILVLYGVFRPFKWVSKAELFRVPFVGWNMWLNDC
HHHCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHC
VPVWRGDRESVRKMMAHCRAHLARGAPVMIFPEGTRSPDGRLQAFKDGAFRLAVDANVPV
HHHCCCCHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHCCCCCEEEEEECCCCE
IPIAVSGTSEALPKHGMVLRQRMRAEVHVLDPIHPSAFDGPAALREAVRDAIAAALPPEH
EEEEECCCHHHCCHHHHHHHHHHHHHEEEECCCCCCCCCCHHHHHHHHHHHHHHHCCCCC
RPGA
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1557036; 9278503 [H]