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The map label for this gene is comF [H]

Identifier: 220915379

GI number: 220915379

Start: 281076

End: 281762

Strand: Direct

Name: comF [H]

Synonym: A2cp1_0258

Alternate gene names: 220915379

Gene position: 281076-281762 (Clockwise)

Preceding gene: 220915378

Following gene: 220915380

Centisome position: 5.59

GC content: 83.41

Gene sequence:

>687_bases
ATGCTCCGCGCCGCCGTCCGCGCCCTGCTCGACCTCGTCTACCCGCCCCGCTGCGCCGCCTGCGGCGAGCCGGTGGCCGA
GGAGCCGTTCTGCGAGGTGTGCGCCGGCGCGCTCGAGCCGGTCCCGCCGGGCTGCGACCGCTGCGGCGCGCCCGGGCCGG
GGCCGGCCTGCGGCGCGTGCCTGGCCGCCCCGCCCGCGTTCGACGTGGTCCGGGCAGGCGGGCTGTTCGGAGGGCCGCTC
GCCGACGCGGTGCACGCGCTGAAGTACGGCGGCCGGCCGGACCTCGCGCGGCCGCTGGGCGCCTGGCTCGCGGCGCGCGT
CCCGCTCCCGCCGGGCGCCGCGGTGGTGTCGGTCCCGCTCGGCCGCGCCCGCCGCATCGCGCGTGGCTACGACCAGGCGG
CGCTGCTCGCCGACGCGCTGGCGCGCGCCGCCGGCGCCCGGGGCCGCCGCCTGCGCGGGGTGCTCCGCCGCGCCCGCGAG
ACGGCGCCGCAGGTGGGCCTGGGCCGCGCCGAGCGCGCCCGCAACGTGGAGGGCGCGTTCCTGGCCGGCCCGGCGGTGGC
CGGCCGCGACCTGGTGCTCGTGGACGACGTCGTCACCACCGGCGCGACCGCCGACGCGGCGGCGCGCGCGCTCCGGGCGG
CGGGCGCCCGGTCGGTCACGGTGGTCGCGCTCGCCCGGGCCGAGTGA

Upstream 100 bases:

>100_bases
AAGGGCCTCGGCCTCGTGATCCGCTAGCGCCCACGCGCCGTCCGGCGGACCCGGGCGGCGCCGCGGCGCGCCCAATGCCT
TCACCCGGAGAGAACCCAGG

Downstream 100 bases:

>100_bases
CGCCGAAGCTGCGGACCGGCGGCGGGACCGGGGTTACACTCGCTCCTCGCATGCTCGCACGCCTCGCCGCCCTGCTCGCG
CTCTGCCTCGCCTGGACGGG

Product: phosphoribosyltransferase

Products: NA

Alternate protein names: DNA transformation protein ComF; Protein COM101A [H]

Number of amino acids: Translated: 228; Mature: 228

Protein sequence:

>228_residues
MLRAAVRALLDLVYPPRCAACGEPVAEEPFCEVCAGALEPVPPGCDRCGAPGPGPACGACLAAPPAFDVVRAGGLFGGPL
ADAVHALKYGGRPDLARPLGAWLAARVPLPPGAAVVSVPLGRARRIARGYDQAALLADALARAAGARGRRLRGVLRRARE
TAPQVGLGRAERARNVEGAFLAGPAVAGRDLVLVDDVVTTGATADAAARALRAAGARSVTVVALARAE

Sequences:

>Translated_228_residues
MLRAAVRALLDLVYPPRCAACGEPVAEEPFCEVCAGALEPVPPGCDRCGAPGPGPACGACLAAPPAFDVVRAGGLFGGPL
ADAVHALKYGGRPDLARPLGAWLAARVPLPPGAAVVSVPLGRARRIARGYDQAALLADALARAAGARGRRLRGVLRRARE
TAPQVGLGRAERARNVEGAFLAGPAVAGRDLVLVDDVVTTGATADAAARALRAAGARSVTVVALARAE
>Mature_228_residues
MLRAAVRALLDLVYPPRCAACGEPVAEEPFCEVCAGALEPVPPGCDRCGAPGPGPACGACLAAPPAFDVVRAGGLFGGPL
ADAVHALKYGGRPDLARPLGAWLAARVPLPPGAAVVSVPLGRARRIARGYDQAALLADALARAAGARGRRLRGVLRRARE
TAPQVGLGRAERARNVEGAFLAGPAVAGRDLVLVDDVVTTGATADAAARALRAAGARSVTVVALARAE

Specific function: Involved in transformation (competence for DNA uptake) [H]

COG id: COG1040

COG function: function code R; Predicted amidophosphoribosyltransferases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ComF/GntX family [H]

Homologues:

Organism=Escherichia coli, GI87082263, Length=235, Percent_Identity=32.3404255319149, Blast_Score=97, Evalue=7e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005222
- InterPro:   IPR000836 [H]

Pfam domain/function: PF00156 Pribosyltran [H]

EC number: NA

Molecular weight: Translated: 22996; Mature: 22996

Theoretical pI: Translated: 9.55; Mature: 9.55

Prosite motif: PS00103 PUR_PYR_PR_TRANSFER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.5 %Cys     (Translated Protein)
0.4 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
3.5 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLRAAVRALLDLVYPPRCAACGEPVAEEPFCEVCAGALEPVPPGCDRCGAPGPGPACGAC
CHHHHHHHHHHHHCCCCHHHCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHH
LAAPPAFDVVRAGGLFGGPLADAVHALKYGGRPDLARPLGAWLAARVPLPPGAAVVSVPL
HCCCCHHHHHHHCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCEEEECCC
GRARRIARGYDQAALLADALARAAGARGRRLRGVLRRARETAPQVGLGRAERARNVEGAF
HHHHHHHHCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCHHHHHCCCCCCE
LAGPAVAGRDLVLVDDVVTTGATADAAARALRAAGARSVTVVALARAE
EECCCCCCCCEEEEHHHHHCCCCHHHHHHHHHHCCCCCEEEEEEECCC
>Mature Secondary Structure
MLRAAVRALLDLVYPPRCAACGEPVAEEPFCEVCAGALEPVPPGCDRCGAPGPGPACGAC
CHHHHHHHHHHHHCCCCHHHCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHH
LAAPPAFDVVRAGGLFGGPLADAVHALKYGGRPDLARPLGAWLAARVPLPPGAAVVSVPL
HCCCCHHHHHHHCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCEEEECCC
GRARRIARGYDQAALLADALARAAGARGRRLRGVLRRARETAPQVGLGRAERARNVEGAF
HHHHHHHHCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCHHHHHCCCCCCE
LAGPAVAGRDLVLVDDVVTTGATADAAARALRAAGARSVTVVALARAE
EECCCCCCCCEEEEHHHHHCCCCHHHHHHHHHHCCCCCEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1916268; 1856167; 7542800 [H]