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The map label for this gene is argB

Identifier: 220915313

GI number: 220915313

Start: 213679

End: 214497

Strand: Direct

Name: argB

Synonym: A2cp1_0192

Alternate gene names: 220915313

Gene position: 213679-214497 (Clockwise)

Preceding gene: 220915312

Following gene: 220915318

Centisome position: 4.25

GC content: 73.75

Gene sequence:

>819_bases
ATGAAGACCATCGTCCTCAAGCTCGGCGGCGAGATCGTCCACTCCCCGGAGCTCGACCTGGTCGCGCGCGACCTGCGCAC
GCTCGTCGACGGCTGGAACCGGGTCGCCATCGTCCACGGCGGCGGCCCGCAGGCGACCGCGCTGCAGAAGCGGCTCGGCC
TCGAGACGCGCATGGTGGCGGGCCGGCGGTTCACCGACGAGGCCACCCTCGAGGTGATGAAGTACGTGGTGGCCGGGCGG
CTCAACGTCGATCTGTGCGGCCGGCTGCTCGCGAACGGCGTCATGCCGGTGGGGCTGCACGGCGCGAGCGGCCACGCCAT
CCAGGCCACCCGCCGGCCGCCGCGGGTGATGCAGGGCGCCGGGCCGGAGCCGGTGGACCTCGGCCTGGTGGGCGACGTGG
TCGGGTTCAACCTGCCGCTCCTCGGCGACCTGTTCGAGCGGCGCTACGTGCCGGTGCTGGCGTGCCTGGGCTGCGACGAC
GCCGGCCAGGCGCTCAACATCAACGGCGACACGGTGGCGAGCCAGCTCGCCGGCGCGCTCCGCGCCGACGCGCTCGTGCT
CGTCACCTCCACCCCGGGCGTGCTCCGCGACGTGAAGGATCCCTCGAGCCGCATCCCGCGCATCACCCGCGCCGAGTTCG
AGCGGCTGGTGGCGGACGGCACCATCTCCGGCGGCATGATCCCGAAGCTGGAGGAGTCGTTCGAGGTGCTGCGCGGCGGC
GCGAGGTCGGTCGTGATCCTGGGGAAGCTCGCGCCCGGCGATCTCGAGGCGGCGCTGCTCGAGCCCGGGTCGGCGGGCAC
GGTGCTCGTGGCGGACTAG

Upstream 100 bases:

>100_bases
ACCTGGTGAAGGGCGGGGCAGGCCAGGCCATCCAGAACATGAACCTCGTGCTCGGGCTCGACGAGAAGGCCTCGCTCGCC
GACCCCGGCCCCTGGCCTCC

Downstream 100 bases:

>100_bases
CGCGGGGCCCCGCCTCCCTCGCCTAGCGCGCCGGCACCTTCTCCAGCACCACCGTGACCGGCTGGAGCCGGCCGCCCACG
TACACACCCTCCTCGGCGAG

Product: acetylglutamate kinase

Products: NA

Alternate protein names: N-acetyl-L-glutamate 5-phosphotransferase; NAG kinase; AGK

Number of amino acids: Translated: 272; Mature: 272

Protein sequence:

>272_residues
MKTIVLKLGGEIVHSPELDLVARDLRTLVDGWNRVAIVHGGGPQATALQKRLGLETRMVAGRRFTDEATLEVMKYVVAGR
LNVDLCGRLLANGVMPVGLHGASGHAIQATRRPPRVMQGAGPEPVDLGLVGDVVGFNLPLLGDLFERRYVPVLACLGCDD
AGQALNINGDTVASQLAGALRADALVLVTSTPGVLRDVKDPSSRIPRITRAEFERLVADGTISGGMIPKLEESFEVLRGG
ARSVVILGKLAPGDLEAALLEPGSAGTVLVAD

Sequences:

>Translated_272_residues
MKTIVLKLGGEIVHSPELDLVARDLRTLVDGWNRVAIVHGGGPQATALQKRLGLETRMVAGRRFTDEATLEVMKYVVAGR
LNVDLCGRLLANGVMPVGLHGASGHAIQATRRPPRVMQGAGPEPVDLGLVGDVVGFNLPLLGDLFERRYVPVLACLGCDD
AGQALNINGDTVASQLAGALRADALVLVTSTPGVLRDVKDPSSRIPRITRAEFERLVADGTISGGMIPKLEESFEVLRGG
ARSVVILGKLAPGDLEAALLEPGSAGTVLVAD
>Mature_272_residues
MKTIVLKLGGEIVHSPELDLVARDLRTLVDGWNRVAIVHGGGPQATALQKRLGLETRMVAGRRFTDEATLEVMKYVVAGR
LNVDLCGRLLANGVMPVGLHGASGHAIQATRRPPRVMQGAGPEPVDLGLVGDVVGFNLPLLGDLFERRYVPVLACLGCDD
AGQALNINGDTVASQLAGALRADALVLVTSTPGVLRDVKDPSSRIPRITRAEFERLVADGTISGGMIPKLEESFEVLRGG
ARSVVILGKLAPGDLEAALLEPGSAGTVLVAD

Specific function: Arginine biosynthesis; second step. [C]

COG id: COG0548

COG function: function code E; Acetylglutamate kinase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetylglutamate kinase family

Homologues:

Organism=Escherichia coli, GI145693208, Length=248, Percent_Identity=30.241935483871, Blast_Score=79, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ARGB_ANAD2 (B8J8V3)

Other databases:

- EMBL:   CP001359
- RefSeq:   YP_002490617.1
- ProteinModelPortal:   B8J8V3
- SMR:   B8J8V3
- GeneID:   7298427
- GenomeReviews:   CP001359_GR
- KEGG:   acp:A2cp1_0192
- HOGENOM:   HBG497643
- ProtClustDB:   CLSK944876
- GO:   GO:0005737
- HAMAP:   MF_00082_B
- InterPro:   IPR004662
- InterPro:   IPR001048
- Gene3D:   G3DSA:3.40.1160.10
- PIRSF:   PIRSF000728
- TIGRFAMs:   TIGR00761

Pfam domain/function: PF00696 AA_kinase; SSF53633 Aa_kinase

EC number: =2.7.2.8

Molecular weight: Translated: 28540; Mature: 28540

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: NA

Important sites: BINDING 63-63 BINDING 166-166

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTIVLKLGGEIVHSPELDLVARDLRTLVDGWNRVAIVHGGGPQATALQKRLGLETRMVA
CCEEEEEECCCEEECCCHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHCCHHHHHC
GRRFTDEATLEVMKYVVAGRLNVDLCGRLLANGVMPVGLHGASGHAIQATRRPPRVMQGA
CCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCEEEEECCCCCEEEECCCCCHHHCCC
GPEPVDLGLVGDVVGFNLPLLGDLFERRYVPVLACLGCDDAGQALNINGDTVASQLAGAL
CCCCEECCEEHHHHHCCCCHHHHHHHHHCHHEEEEECCCCCCCEEECCCHHHHHHHHHHH
RADALVLVTSTPGVLRDVKDPSSRIPRITRAEFERLVADGTISGGMIPKLEESFEVLRGG
CCCEEEEEECCCHHHHHCCCCHHHCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCC
ARSVVILGKLAPGDLEAALLEPGSAGTVLVAD
CCEEEEEEECCCCCCCEEEECCCCCCEEEEEC
>Mature Secondary Structure
MKTIVLKLGGEIVHSPELDLVARDLRTLVDGWNRVAIVHGGGPQATALQKRLGLETRMVA
CCEEEEEECCCEEECCCHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHCCHHHHHC
GRRFTDEATLEVMKYVVAGRLNVDLCGRLLANGVMPVGLHGASGHAIQATRRPPRVMQGA
CCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCEEEEECCCCCEEEECCCCCHHHCCC
GPEPVDLGLVGDVVGFNLPLLGDLFERRYVPVLACLGCDDAGQALNINGDTVASQLAGAL
CCCCEECCEEHHHHHCCCCHHHHHHHHHCHHEEEEECCCCCCCEEECCCHHHHHHHHHHH
RADALVLVTSTPGVLRDVKDPSSRIPRITRAEFERLVADGTISGGMIPKLEESFEVLRGG
CCCEEEEEECCCHHHHHCCCCHHHCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCC
ARSVVILGKLAPGDLEAALLEPGSAGTVLVAD
CCEEEEEEECCCCCCCEEEECCCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA