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The map label for this gene is glcK [H]

Identifier: 220915300

GI number: 220915300

Start: 196868

End: 197830

Strand: Direct

Name: glcK [H]

Synonym: A2cp1_0179

Alternate gene names: 220915300

Gene position: 196868-197830 (Clockwise)

Preceding gene: 220915299

Following gene: 220915301

Centisome position: 3.91

GC content: 77.26

Gene sequence:

>963_bases
GTGAAGGGGCTCGCGCTGGGCGTTGACCTGGGGGGCACCAACGCGCGCGCCGCGGTGGTGGACCGCGCCACCGGCGAGAT
CGTGGCCTCGCACAAGGAGCCGCTGCGCGAGCGCGGACCCGAGGCGGTGGTCGCGACCGTCCTCCACGCGCTCGGGCAGG
CGGCCGGCGCCGCCGGGATCGCGCCGGCGTCCGCGGGCCGGGTCGGGGTGGGCGTGGCCGGGCAGGTGCTCGGCGCCACC
GGCGTGGTGATGAACGCGCCCAACCTGGGCTGGCGCGACGTGGCGTTCGGCACGCTGCTGGAGAAGGCGCTCGGCGTGCC
GGTGCGGGTCGCGAACGACCTGTCGGTGGCGGCCTGGGGCGAGAAGCGCTTCGGCGCCGCCCGCGGCATCGAGGACGTGG
TGCTGGTGTTCGTCGGCTCCGGCGTGGGCTCCGGCCTCATCCTCGGTGGCCGGCTGCACGACGGCGCCCAGGGGGTGGCC
GGCGAGCTCGGGCACATCAAGGTGCGCCTGCCGCGCCCGGGGTTCACGCCGCGCCGCTGCGGCTGCGGCCAGCTCGGCTG
CCTCGAGGCGTACACCTCGGGGGTGAACGTGGCCGCGCGCGTGCGCGAGGAGATCGCGGCCGGCGCCGCCACCCGCGTGC
TCGAGCTGGTGGAGGGCGACCTCGCCCGCGTCACCGCCAGCGTGGTGGAGGAGGCGCACGCGCTGGGCGACGCCTACGCC
GTGGCGCTGTGGGACGAGGTCGCGGAGCTGCTCGGCCTCTCCGTGGCGAACCTGGTCACGCTGCTCAACCCCGCCCGGCT
CATCCTGGGGGGCGGCGTGCTGCTGGGCGCACCCCGCCTCGCCGACCTGACGCTCCGCCGCTTCGACGAGGCGGTATCGC
GCTCGGCCACGCGGGGGCTCACCGTGGAGCGCGCGTGGCTCGGCGACGACGCCGGGGTCATCGGCGCCGCCGTGCTCGAG
TAG

Upstream 100 bases:

>100_bases
CCTGCGCTTCGAGGCGAAGACCGAGGCGCGGCTCGCCGAGATCCAGGCGCTGGTGCGCGGCAAGGTCGACGAGCTGCTGC
GCGAGCTGGGGGCGTAGGCC

Downstream 100 bases:

>100_bases
ATCGAAGGGGTGTCCGCGAAGGCCACGCCTGCCCGGCGCCTCGACGCGTCGGGAGGCGCGCCGCGCGCGCGCGGAGACGC
GGCCGGGCCGCGCCGCGGGC

Product: ROK family protein

Products: NA

Alternate protein names: Glucose kinase [H]

Number of amino acids: Translated: 320; Mature: 320

Protein sequence:

>320_residues
MKGLALGVDLGGTNARAAVVDRATGEIVASHKEPLRERGPEAVVATVLHALGQAAGAAGIAPASAGRVGVGVAGQVLGAT
GVVMNAPNLGWRDVAFGTLLEKALGVPVRVANDLSVAAWGEKRFGAARGIEDVVLVFVGSGVGSGLILGGRLHDGAQGVA
GELGHIKVRLPRPGFTPRRCGCGQLGCLEAYTSGVNVAARVREEIAAGAATRVLELVEGDLARVTASVVEEAHALGDAYA
VALWDEVAELLGLSVANLVTLLNPARLILGGGVLLGAPRLADLTLRRFDEAVSRSATRGLTVERAWLGDDAGVIGAAVLE

Sequences:

>Translated_320_residues
MKGLALGVDLGGTNARAAVVDRATGEIVASHKEPLRERGPEAVVATVLHALGQAAGAAGIAPASAGRVGVGVAGQVLGAT
GVVMNAPNLGWRDVAFGTLLEKALGVPVRVANDLSVAAWGEKRFGAARGIEDVVLVFVGSGVGSGLILGGRLHDGAQGVA
GELGHIKVRLPRPGFTPRRCGCGQLGCLEAYTSGVNVAARVREEIAAGAATRVLELVEGDLARVTASVVEEAHALGDAYA
VALWDEVAELLGLSVANLVTLLNPARLILGGGVLLGAPRLADLTLRRFDEAVSRSATRGLTVERAWLGDDAGVIGAAVLE
>Mature_320_residues
MKGLALGVDLGGTNARAAVVDRATGEIVASHKEPLRERGPEAVVATVLHALGQAAGAAGIAPASAGRVGVGVAGQVLGAT
GVVMNAPNLGWRDVAFGTLLEKALGVPVRVANDLSVAAWGEKRFGAARGIEDVVLVFVGSGVGSGLILGGRLHDGAQGVA
GELGHIKVRLPRPGFTPRRCGCGQLGCLEAYTSGVNVAARVREEIAAGAATRVLELVEGDLARVTASVVEEAHALGDAYA
VALWDEVAELLGLSVANLVTLLNPARLILGGGVLLGAPRLADLTLRRFDEAVSRSATRGLTVERAWLGDDAGVIGAAVLE

Specific function: Acts As A Repressor Of The Nagebacd Operon And Acts Both As An Activator And A Repressor For The Transcription Of The Glmsu Operon. [C]

COG id: COG1940

COG function: function code KG; Transcriptional regulator/sugar kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ROK (nagC/xylR) family [H]

Homologues:

Organism=Homo sapiens, GI190014632, Length=274, Percent_Identity=36.1313868613139, Blast_Score=105, Evalue=6e-23,
Organism=Homo sapiens, GI298566315, Length=274, Percent_Identity=36.1313868613139, Blast_Score=105, Evalue=7e-23,
Organism=Homo sapiens, GI298566325, Length=274, Percent_Identity=36.1313868613139, Blast_Score=105, Evalue=7e-23,
Organism=Homo sapiens, GI4885285, Length=274, Percent_Identity=36.1313868613139, Blast_Score=105, Evalue=7e-23,
Organism=Escherichia coli, GI1786891, Length=271, Percent_Identity=28.4132841328413, Blast_Score=105, Evalue=3e-24,
Organism=Escherichia coli, GI87081733, Length=334, Percent_Identity=30.5389221556886, Blast_Score=101, Evalue=6e-23,
Organism=Escherichia coli, GI1787363, Length=328, Percent_Identity=27.7439024390244, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1787878, Length=273, Percent_Identity=26.007326007326, Blast_Score=79, Evalue=5e-16,
Organism=Escherichia coli, GI87082127, Length=215, Percent_Identity=26.5116279069767, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1790522, Length=330, Percent_Identity=26.6666666666667, Blast_Score=68, Evalue=9e-13,
Organism=Escherichia coli, GI87082230, Length=214, Percent_Identity=32.7102803738318, Blast_Score=62, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000600
- InterPro:   IPR004654 [H]

Pfam domain/function: PF00480 ROK [H]

EC number: =2.7.1.2 [H]

Molecular weight: Translated: 32389; Mature: 32389

Theoretical pI: Translated: 6.37; Mature: 6.37

Prosite motif: PS01125 ROK

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKGLALGVDLGGTNARAAVVDRATGEIVASHKEPLRERGPEAVVATVLHALGQAAGAAGI
CCCEEEEEECCCCCCCEEEEECCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCC
APASAGRVGVGVAGQVLGATGVVMNAPNLGWRDVAFGTLLEKALGVPVRVANDLSVAAWG
CCCCCCCCCCCHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHHHCCCEEECCCCEEEECC
EKRFGAARGIEDVVLVFVGSGVGSGLILGGRLHDGAQGVAGELGHIKVRLPRPGFTPRRC
CHHHHHHCCHHHEEEEEECCCCCCCEEEECCCCCCCCCCCCCCCEEEEEECCCCCCCCCC
GCGQLGCLEAYTSGVNVAARVREEIAAGAATRVLELVEGDLARVTASVVEEAHALGDAYA
CCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCHHHH
VALWDEVAELLGLSVANLVTLLNPARLILGGGVLLGAPRLADLTLRRFDEAVSRSATRGL
HHHHHHHHHHHCCHHHHHHHHHCCHHHEECCCCEECCCHHHHHHHHHHHHHHHHHHHCCC
TVERAWLGDDAGVIGAAVLE
EEEEEECCCCCCHHHHHHCC
>Mature Secondary Structure
MKGLALGVDLGGTNARAAVVDRATGEIVASHKEPLRERGPEAVVATVLHALGQAAGAAGI
CCCEEEEEECCCCCCCEEEEECCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCC
APASAGRVGVGVAGQVLGATGVVMNAPNLGWRDVAFGTLLEKALGVPVRVANDLSVAAWG
CCCCCCCCCCCHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHHHCCCEEECCCCEEEECC
EKRFGAARGIEDVVLVFVGSGVGSGLILGGRLHDGAQGVAGELGHIKVRLPRPGFTPRRC
CHHHHHHCCHHHEEEEEECCCCCCCEEEECCCCCCCCCCCCCCCEEEEEECCCCCCCCCC
GCGQLGCLEAYTSGVNVAARVREEIAAGAATRVLELVEGDLARVTASVVEEAHALGDAYA
CCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCHHHH
VALWDEVAELLGLSVANLVTLLNPARLILGGGVLLGAPRLADLTLRRFDEAVSRSATRGL
HHHHHHHHHHHCCHHHHHHHHHCCHHHEECCCCEECCCHHHHHHHHHHHHHHHHHHHCCC
TVERAWLGDDAGVIGAAVLE
EEEEEECCCCCCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]