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The map label for this gene is dinB [H]

Identifier: 220915280

GI number: 220915280

Start: 177561

End: 178817

Strand: Direct

Name: dinB [H]

Synonym: A2cp1_0159

Alternate gene names: 220915280

Gene position: 177561-178817 (Clockwise)

Preceding gene: 220915275

Following gene: 220915281

Centisome position: 3.53

GC content: 77.17

Gene sequence:

>1257_bases
ATGTACAGGGCGATGGATCCGGGGCCCCGCACCATCCTCCACCTCGACCTCGACGCGTTCTACGCGTCGGTGGAGCAGCT
CGACCACCCCGAGCTGCGCGGCCGGCCGGTGATCGTGGGGGGGACCGGCAACCGAGGGGTGGTGTGCGCGGCGAGCTACG
AGGCGCGGAAGTTCGGCGTCCGCTCGGCGCTGCCCACGGCCCGGGCCCGCCGGCTCTGCCCGGACGGCGTGTTCCTCCCG
CCCCGGTTCGGCCGCTACTCGGAGCTGTCGCGGCGGGTGTTCGACGTCTACCGGCGCTACACGCCGCTGGTGGAGCCGCT
CTCGCTCGACGAGGCGTTCCTCGACGTCAGCGCCAGCCGGGCGCTGCACGGCACCGGGCCGGAGATCGCGCGGGCCATCA
AGGTGGCGGTCCGGGGCGAGTGCGGCCTGGCGGTGTCGGCCGGCGTGGCCGAGGTGAAGATGGCGGCCAAGATCGCCACC
GACCTCGGCAAGCCGGACGGGCTGGTGGTGGTGCCGGCGGGCGGCGTGGCGGCGTTCCTGGCGCCCTTGCCGGTGGGGCG
GCTGTGGGGCGTGGGCGAGGTGACCGAGGCCACGCTCCGGCGCATCGGCGTCGCCACCATCGGCGACCTCGCCCGCATGC
CGGAGTCGGCGCTCGCCGCGGCGCTCGGGCCCAACCACGCGCGCGGGCTGCGCGCGCTCGCGCGAGGCGAGGACGCGCGC
GAGGTGGTGCCGGACGAGGAGGCGAAGTCGGTCGGGGCCGAGGACACCTTCGACCACGACCTGCTCGGCCGCACGGCGCT
CGAGCGCGAGCTGCTCGCGCAGGCGGGCACGGTGGGGCGGCGGCTCCGCGCGGCCGGGCTCGCCGGCCACGTGGTGACGC
TCAAGGTGAAGTACGCCGACTTCACGCTGGTGACGCGCCGGGTGACGCTCGAGCGGGCCACCGACGACGACCGCGCCATC
TTCGAGGCGGCGCGCGCGCAGCTCGAGCGCGTGGACCTGCGCCGGCCGGTGCGCCTCACCGGCATCTCGGTGTCCGGCTT
CGCCGGGGACGAGGAGCGCGGGCAGCTCGGACTCTTCGGTGGGGCGCCCGCTCCCCCGCCGCCCGAGGCGTCCCGGCGCA
AGGCGCTCAACGCGGCGCTCGACGCGCTGGCGGGCCGCTTCGGGGAGGGCGCGGTGACGCGGGCCGACCTGGCCGGCCGG
CCGCCCCGGCGGCGCCACGGGGATCCCGGGGACGGCGGCGAGGATCCCGACCGGTGA

Upstream 100 bases:

>100_bases
GGTAGCCACCGATCCGTCCATGCAAGCCGCTACTTACCGGGCCACTTGATCAGGATCAAGTGGCGCGGCGTCCCCGTTGG
GCACGGCAGGGGGTTGTCCT

Downstream 100 bases:

>100_bases
GGGAGCCGCGGTTTGCCCCGTGGCGCGCGGCGCCGCAGGTTGACGGGCATGGCCGCAGCCATACGTCCGGGCGAGGACCT
CGCCATCCGGGAGCGGAGCC

Product: DNA-directed DNA polymerase

Products: NA

Alternate protein names: Pol IV [H]

Number of amino acids: Translated: 418; Mature: 418

Protein sequence:

>418_residues
MYRAMDPGPRTILHLDLDAFYASVEQLDHPELRGRPVIVGGTGNRGVVCAASYEARKFGVRSALPTARARRLCPDGVFLP
PRFGRYSELSRRVFDVYRRYTPLVEPLSLDEAFLDVSASRALHGTGPEIARAIKVAVRGECGLAVSAGVAEVKMAAKIAT
DLGKPDGLVVVPAGGVAAFLAPLPVGRLWGVGEVTEATLRRIGVATIGDLARMPESALAAALGPNHARGLRALARGEDAR
EVVPDEEAKSVGAEDTFDHDLLGRTALERELLAQAGTVGRRLRAAGLAGHVVTLKVKYADFTLVTRRVTLERATDDDRAI
FEAARAQLERVDLRRPVRLTGISVSGFAGDEERGQLGLFGGAPAPPPPEASRRKALNAALDALAGRFGEGAVTRADLAGR
PPRRRHGDPGDGGEDPDR

Sequences:

>Translated_418_residues
MYRAMDPGPRTILHLDLDAFYASVEQLDHPELRGRPVIVGGTGNRGVVCAASYEARKFGVRSALPTARARRLCPDGVFLP
PRFGRYSELSRRVFDVYRRYTPLVEPLSLDEAFLDVSASRALHGTGPEIARAIKVAVRGECGLAVSAGVAEVKMAAKIAT
DLGKPDGLVVVPAGGVAAFLAPLPVGRLWGVGEVTEATLRRIGVATIGDLARMPESALAAALGPNHARGLRALARGEDAR
EVVPDEEAKSVGAEDTFDHDLLGRTALERELLAQAGTVGRRLRAAGLAGHVVTLKVKYADFTLVTRRVTLERATDDDRAI
FEAARAQLERVDLRRPVRLTGISVSGFAGDEERGQLGLFGGAPAPPPPEASRRKALNAALDALAGRFGEGAVTRADLAGR
PPRRRHGDPGDGGEDPDR
>Mature_418_residues
MYRAMDPGPRTILHLDLDAFYASVEQLDHPELRGRPVIVGGTGNRGVVCAASYEARKFGVRSALPTARARRLCPDGVFLP
PRFGRYSELSRRVFDVYRRYTPLVEPLSLDEAFLDVSASRALHGTGPEIARAIKVAVRGECGLAVSAGVAEVKMAAKIAT
DLGKPDGLVVVPAGGVAAFLAPLPVGRLWGVGEVTEATLRRIGVATIGDLARMPESALAAALGPNHARGLRALARGEDAR
EVVPDEEAKSVGAEDTFDHDLLGRTALERELLAQAGTVGRRLRAAGLAGHVVTLKVKYADFTLVTRRVTLERATDDDRAI
FEAARAQLERVDLRRPVRLTGISVSGFAGDEERGQLGLFGGAPAPPPPEASRRKALNAALDALAGRFGEGAVTRADLAGR
PPRRRHGDPGDGGEDPDR

Specific function: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits

COG id: COG0389

COG function: function code L; Nucleotidyltransferase/DNA polymerase involved in DNA repair

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 umuC domain [H]

Homologues:

Organism=Homo sapiens, GI84043967, Length=403, Percent_Identity=28.0397022332506, Blast_Score=144, Evalue=1e-34,
Organism=Homo sapiens, GI7706681, Length=404, Percent_Identity=27.970297029703, Blast_Score=144, Evalue=2e-34,
Organism=Homo sapiens, GI154350220, Length=327, Percent_Identity=27.5229357798165, Blast_Score=120, Evalue=3e-27,
Organism=Homo sapiens, GI7705344, Length=122, Percent_Identity=40.1639344262295, Blast_Score=108, Evalue=7e-24,
Organism=Homo sapiens, GI5729982, Length=118, Percent_Identity=33.0508474576271, Blast_Score=71, Evalue=2e-12,
Organism=Escherichia coli, GI1786425, Length=349, Percent_Identity=38.3954154727794, Blast_Score=209, Evalue=3e-55,
Organism=Escherichia coli, GI1787432, Length=400, Percent_Identity=26, Blast_Score=99, Evalue=5e-22,
Organism=Caenorhabditis elegans, GI193205700, Length=411, Percent_Identity=27.7372262773723, Blast_Score=139, Evalue=2e-33,
Organism=Caenorhabditis elegans, GI193205702, Length=357, Percent_Identity=26.0504201680672, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17537959, Length=297, Percent_Identity=26.5993265993266, Blast_Score=97, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI115534089, Length=123, Percent_Identity=39.8373983739837, Blast_Score=81, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6324921, Length=259, Percent_Identity=24.3243243243243, Blast_Score=79, Evalue=2e-15,
Organism=Drosophila melanogaster, GI21355641, Length=283, Percent_Identity=30.0353356890459, Blast_Score=126, Evalue=2e-29,
Organism=Drosophila melanogaster, GI24644984, Length=283, Percent_Identity=30.0353356890459, Blast_Score=126, Evalue=2e-29,
Organism=Drosophila melanogaster, GI19923006, Length=337, Percent_Identity=25.2225519287834, Blast_Score=112, Evalue=4e-25,
Organism=Drosophila melanogaster, GI24668444, Length=183, Percent_Identity=26.775956284153, Blast_Score=73, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017962
- InterPro:   IPR017961
- InterPro:   IPR001126
- InterPro:   IPR017963
- InterPro:   IPR022880 [H]

Pfam domain/function: PF00817 IMS [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 44463; Mature: 44463

Theoretical pI: Translated: 9.38; Mature: 9.38

Prosite motif: PS50173 UMUC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYRAMDPGPRTILHLDLDAFYASVEQLDHPELRGRPVIVGGTGNRGVVCAASYEARKFGV
CCCCCCCCCCEEEEEEHHHHHHHHHHCCCCCCCCCEEEEECCCCCCEEEEECCHHHHHHH
RSALPTARARRLCPDGVFLPPRFGRYSELSRRVFDVYRRYTPLVEPLSLDEAFLDVSASR
HHCCCHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHC
ALHGTGPEIARAIKVAVRGECGLAVSAGVAEVKMAAKIATDLGKPDGLVVVPAGGVAAFL
CCCCCCHHHHHHHHHHCCCCCCEEECCCHHHHHHHHHHHHHCCCCCCEEEECCCCHHHHH
APLPVGRLWGVGEVTEATLRRIGVATIGDLARMPESALAAALGPNHARGLRALARGEDAR
HHCCCHHHCCCCHHHHHHHHHHCHHHHHHHHHCCHHHHHHHCCCCHHHHHHHHHCCCCHH
EVVPDEEAKSVGAEDTFDHDLLGRTALERELLAQAGTVGRRLRAAGLAGHVVTLKVKYAD
HCCCCHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEECC
FTLVTRRVTLERATDDDRAIFEAARAQLERVDLRRPVRLTGISVSGFAGDEERGQLGLFG
EEEEEEEEEEECCCCHHHHHHHHHHHHHHHHHCCCCEEEEEEEEECCCCCCCCCCEEEEC
GAPAPPPPEASRRKALNAALDALAGRFGEGAVTRADLAGRPPRRRHGDPGDGGEDPDR
CCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEHHCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MYRAMDPGPRTILHLDLDAFYASVEQLDHPELRGRPVIVGGTGNRGVVCAASYEARKFGV
CCCCCCCCCCEEEEEEHHHHHHHHHHCCCCCCCCCEEEEECCCCCCEEEEECCHHHHHHH
RSALPTARARRLCPDGVFLPPRFGRYSELSRRVFDVYRRYTPLVEPLSLDEAFLDVSASR
HHCCCHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHC
ALHGTGPEIARAIKVAVRGECGLAVSAGVAEVKMAAKIATDLGKPDGLVVVPAGGVAAFL
CCCCCCHHHHHHHHHHCCCCCCEEECCCHHHHHHHHHHHHHCCCCCCEEEECCCCHHHHH
APLPVGRLWGVGEVTEATLRRIGVATIGDLARMPESALAAALGPNHARGLRALARGEDAR
HHCCCHHHCCCCHHHHHHHHHHCHHHHHHHHHCCHHHHHHHCCCCHHHHHHHHHCCCCHH
EVVPDEEAKSVGAEDTFDHDLLGRTALERELLAQAGTVGRRLRAAGLAGHVVTLKVKYAD
HCCCCHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEECC
FTLVTRRVTLERATDDDRAIFEAARAQLERVDLRRPVRLTGISVSGFAGDEERGQLGLFG
EEEEEEEEEEECCCCHHHHHHHHHHHHHHHHHCCCCEEEEEEEEECCCCCCCCCCEEEEC
GAPAPPPPEASRRKALNAALDALAGRFGEGAVTRADLAGRPPRRRHGDPGDGGEDPDR
CCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEHHCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA