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The map label for this gene is upp [C]

Identifier: 220915265

GI number: 220915265

Start: 160186

End: 161001

Strand: Direct

Name: upp [C]

Synonym: A2cp1_0144

Alternate gene names: 220915265

Gene position: 160186-161001 (Clockwise)

Preceding gene: 220915264

Following gene: 220915266

Centisome position: 3.19

GC content: 68.63

Gene sequence:

>816_bases
GTGCGAGACCTGAGCTACGACCACGTCCCCTACCGGATGAGCGAGATCGAGCACCGGTACGGCGAGAACGTCCACATCGT
CGCGAACCCCTTCCTGCTGGGCGCGCTCGCCACGCTGTGCTCGAAGGAGACCCGCCAGCCGGCCATCAACCGGCTGGTCC
GGCTGCTGTACGAGGACCTCATCCGCACCGTGATGAACCACGAGTTCCCGCGGCGCCGGGTGGCGGTCCCCACCCGCATG
ATCGACAGCTCGCCGCAGGCGATCTTCGAGGGCGAGGTGGTCGACCGGCAGGTGCGCGCGGTGACGGTGAACATCGCCCG
CGCCGGCGCGGTCCCGTCGCAGCTCGTCTACGACCTGCTCAACGAGACGCTCGAGCCGTCGCTGGTCCGCCAGGATCACA
TCATCATGAGCCGGATGCTGGGCGAGAACGAGGAGGTCGTCGGCGCCGGCATCGGCGGGATGAAGATCGGCGGGGACGTG
GACGACGCGTTCCTGCTCTTCCCGGACCCGATGGGCGCGACCGGCTCGTCGCTCGCGACCGCCATCGAGACCTACAAGAA
GAAGGTGCCGGGGAAGGCGAGGCGGATCGTGAACATCCACCTCATCGTCACCCCCGAGTACCTGCGCAACATGACGAAGG
CCCACCCCGACGTGCGGATCTACGCGATCCGGCTCGACCGCGGCCTCTCCCCGCCCGACGTCCTCGCGACCGTCCCCGGC
ACGCGCTGGGACGAGGAGCGCGGGCTCGACGACCACCAGTACATCGTCCCCGGGGGCGGCGGCTTCGGGGAGATCATGAA
CAACGCCTATGTCTAG

Upstream 100 bases:

>100_bases
AGGTGAGCCGCCGCCAGGTGCCCCCCGCGCCGGCTCCCCGCGCCCGGGGCGCAAATTTGGCAGGACGCTTCCGGGCCGAG
CCGCATTATGCTCCCGGCCC

Downstream 100 bases:

>100_bases
CAGCCGCGCCGGCCTCGACGTGCTCATCTCCGAGGCGGACCTCCGGGCCCGCGTCGCGCAGATGGGCGCCGACATCACCC
GCGACTACGCGGGGAAGAAC

Product: hypothetical protein

Products: Diphosphate; UMP [C]

Alternate protein names: None

Number of amino acids: Translated: 271; Mature: 271

Protein sequence:

>271_residues
MRDLSYDHVPYRMSEIEHRYGENVHIVANPFLLGALATLCSKETRQPAINRLVRLLYEDLIRTVMNHEFPRRRVAVPTRM
IDSSPQAIFEGEVVDRQVRAVTVNIARAGAVPSQLVYDLLNETLEPSLVRQDHIIMSRMLGENEEVVGAGIGGMKIGGDV
DDAFLLFPDPMGATGSSLATAIETYKKKVPGKARRIVNIHLIVTPEYLRNMTKAHPDVRIYAIRLDRGLSPPDVLATVPG
TRWDEERGLDDHQYIVPGGGGFGEIMNNAYV

Sequences:

>Translated_271_residues
MRDLSYDHVPYRMSEIEHRYGENVHIVANPFLLGALATLCSKETRQPAINRLVRLLYEDLIRTVMNHEFPRRRVAVPTRM
IDSSPQAIFEGEVVDRQVRAVTVNIARAGAVPSQLVYDLLNETLEPSLVRQDHIIMSRMLGENEEVVGAGIGGMKIGGDV
DDAFLLFPDPMGATGSSLATAIETYKKKVPGKARRIVNIHLIVTPEYLRNMTKAHPDVRIYAIRLDRGLSPPDVLATVPG
TRWDEERGLDDHQYIVPGGGGFGEIMNNAYV
>Mature_271_residues
MRDLSYDHVPYRMSEIEHRYGENVHIVANPFLLGALATLCSKETRQPAINRLVRLLYEDLIRTVMNHEFPRRRVAVPTRM
IDSSPQAIFEGEVVDRQVRAVTVNIARAGAVPSQLVYDLLNETLEPSLVRQDHIIMSRMLGENEEVVGAGIGGMKIGGDV
DDAFLLFPDPMGATGSSLATAIETYKKKVPGKARRIVNIHLIVTPEYLRNMTKAHPDVRIYAIRLDRGLSPPDVLATVPG
TRWDEERGLDDHQYIVPGGGGFGEIMNNAYV

Specific function: Pyrimidine salvage pathway. [C]

COG id: COG0035

COG function: function code F; Uracil phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Saccharomyces cerevisiae, GI6321920, Length=265, Percent_Identity=26.7924528301887, Blast_Score=65, Evalue=8e-12,

Paralogues:

None

Copy number: 2580 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 2.4.2.9 [C]

Molecular weight: Translated: 30225; Mature: 30225

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS00228 TUBULIN_B_AUTOREG

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRDLSYDHVPYRMSEIEHRYGENVHIVANPFLLGALATLCSKETRQPAINRLVRLLYEDL
CCCCCCCCCCHHHHHHHHHHCCCEEEEECHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
IRTVMNHEFPRRRVAVPTRMIDSSPQAIFEGEVVDRQVRAVTVNIARAGAVPSQLVYDLL
HHHHHCCCCCCHHHCCCHHHHCCCCCCEECCHHHHCEEEEEEEEHHHCCCCHHHHHHHHH
NETLEPSLVRQDHIIMSRMLGENEEVVGAGIGGMKIGGDVDDAFLLFPDPMGATGSSLAT
HHHCCCHHHHHHHHHHHHHHCCCCCEEECCCCCEECCCCCCCEEEEECCCCCCCHHHHHH
AIETYKKKVPGKARRIVNIHLIVTPEYLRNMTKAHPDVRIYAIRLDRGLSPPDVLATVPG
HHHHHHHHCCCCCEEEEEEEEEECHHHHHHHHHCCCCEEEEEEEECCCCCCCHHEEECCC
TRWDEERGLDDHQYIVPGGGGFGEIMNNAYV
CCCHHHCCCCCCEEEEECCCCHHHHHHCCCC
>Mature Secondary Structure
MRDLSYDHVPYRMSEIEHRYGENVHIVANPFLLGALATLCSKETRQPAINRLVRLLYEDL
CCCCCCCCCCHHHHHHHHHHCCCEEEEECHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
IRTVMNHEFPRRRVAVPTRMIDSSPQAIFEGEVVDRQVRAVTVNIARAGAVPSQLVYDLL
HHHHHCCCCCCHHHCCCHHHHCCCCCCEECCHHHHCEEEEEEEEHHHCCCCHHHHHHHHH
NETLEPSLVRQDHIIMSRMLGENEEVVGAGIGGMKIGGDVDDAFLLFPDPMGATGSSLAT
HHHCCCHHHHHHHHHHHHHHCCCCCEEECCCCCEECCCCCCCEEEEECCCCCCCHHHHHH
AIETYKKKVPGKARRIVNIHLIVTPEYLRNMTKAHPDVRIYAIRLDRGLSPPDVLATVPG
HHHHHHHHCCCCCEEEEEEEEEECHHHHHHHHHCCCCEEEEEEEECCCCCCCHHEEECCC
TRWDEERGLDDHQYIVPGGGGFGEIMNNAYV
CCCHHHCCCCCCEEEEECCCCHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 5-Phospho-alpha-D-ribose 1-diphosphate; Uracil [C]

Specific reaction: 5-Phospho-alpha-D-ribose 1-diphosphate + Uracil --> Diphosphate + UMP [C]

General reaction: Pentosyl group transfer [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA