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The map label for this gene is pqqL [C]

Identifier: 220915241

GI number: 220915241

Start: 134502

End: 135878

Strand: Direct

Name: pqqL [C]

Synonym: A2cp1_0120

Alternate gene names: 220915241

Gene position: 134502-135878 (Clockwise)

Preceding gene: 220915239

Following gene: 220915242

Centisome position: 2.67

GC content: 73.35

Gene sequence:

>1377_bases
ATGATCGCGAGCCCGCTCCTCGTCGCAGCGCTCCTCACCGCAGCGCCCGCGGCCGCCGCCCCGCCGCCCGGCGACGCGCC
CGAGATCCCGTACACCATGTTCACCCTCGGGAACGGCCTCACCGTGATCCTGCACGAGGATCACACCGCCCCCCTCGTCG
GCGTCCACGTCCAGTACGACGTGGGCTCGAAGGACGAGCGCCCCGGCCGCACCGGCTTCGCGCACCTGTTCGAGCACCTC
ATGTTCCAGGGCAGCGCGCACCTGCCCAAGGGCGAGGCCGACCGGCTGGTCGACGCGGCCGGCGGCGAGGCGAACGGCGG
GACCAGCCCGGACAGCACCGTGTACTGGGAGCAGGTGCCCTCCGGCGCGCTCGAGCAGATGCTGTTCATCGAGGCCGACC
GGATGGGCTGGATGTTCCCCACGCTCACCCAGGAGAAGCTCGACAACCAGCGCGACGTGGTGCGGAACGAGCGGCGGCAG
TCCTACGAGATGCAGCCGTACGGCCTCGTGTTCGAGAAGCTCCTCGCGAACCTGTGGGATCCCGAGTTCCCCTACCACTG
GCAGACCATCGGCACGCACGAGGACCTGGAGGCCGCCACCCTCGCCGACGTGAAGCAGTTCTTCGAGCGCTGGTACGGGC
CGGAGAACGCGGTGCTCGCCATCGCCGGCGACATCGACCCGGCGCGGACGCGCGCGCTGGTGGAGAAGTGGTTCGGGCCC
ATCCCCGGGAAGGCGCGGCCGGCGCACCAGCCGCCGGCGCCGAAGCCGCTCGCGGCGGAGCAGCGCGTCTCGATGGACGA
CCGCGTGCAGCTTCCCCGGCTGTACCTCGCCTGGCAGACGCCGCGGGTGTTCGCGCCGGGCGACGCGGCGCTGGACGTGC
TCTCGAGCGTGCTCTCCGACGGCAAGAGCGCGCGCCTGGTGAAGCGGCTGGTGATGGACGAGCAGATCGCGCAGGGCGTC
TCGGCCGGGCAGATGAGCCAGGCGCTCGCGAGCATGTACCTGGTGGTCGCGACGCCGAAGCCGGGCATCCCGCTCGAGCG
GCTGGAGCGCGAGATCGACGAGGAGCTGGCGCGGATCGCGCGCGAGCCGCCCTCGGCCGAGGAGGTGCAGCGCGCCAAGA
ACAAGATCGAGGCCGGCGCGGTGTTCGGCCTCGAGCCGGTGGGGGGCTTCGGCGGGCGCGCCGCCTCGCTGGCCGGCTAC
TACGTGCGCACCGGCGACCCCGGGTACCTCGCGAAGGACCTGGCCCGCTACCGCGCGGTGACGCCCGCCGACGTCTCCGA
GGCCGCCCGCCGCTTCCTGCGCAAGGACGCGCGCGTGGTCCTCACCGTCCACCCCAGGCCGGCGGCCGCCGGCGCCGCCG
CCGGGAGCGCCCGATGA

Upstream 100 bases:

>100_bases
ACCGCCCCGTCGTGCCTCGTGCGGGCGGGGGCATGTCCGGCAGGTCGGCCACCGGCGGGCCGTGACGGGCGGCCGGTCGC
GGCATATAACGCGAGGCGCC

Downstream 100 bases:

>100_bases
CCCGCAGCCTCCGCCTCCTCGCCGTCCTCCTCGCCGCCGCGCTCGGCTGCGCCGGCTCCAGGCCGGCCCCTGCGCCGGCC
GCGCCCGCCGCGGCGCCGCA

Product: peptidase M16 domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 458; Mature: 458

Protein sequence:

>458_residues
MIASPLLVAALLTAAPAAAAPPPGDAPEIPYTMFTLGNGLTVILHEDHTAPLVGVHVQYDVGSKDERPGRTGFAHLFEHL
MFQGSAHLPKGEADRLVDAAGGEANGGTSPDSTVYWEQVPSGALEQMLFIEADRMGWMFPTLTQEKLDNQRDVVRNERRQ
SYEMQPYGLVFEKLLANLWDPEFPYHWQTIGTHEDLEAATLADVKQFFERWYGPENAVLAIAGDIDPARTRALVEKWFGP
IPGKARPAHQPPAPKPLAAEQRVSMDDRVQLPRLYLAWQTPRVFAPGDAALDVLSSVLSDGKSARLVKRLVMDEQIAQGV
SAGQMSQALASMYLVVATPKPGIPLERLEREIDEELARIAREPPSAEEVQRAKNKIEAGAVFGLEPVGGFGGRAASLAGY
YVRTGDPGYLAKDLARYRAVTPADVSEAARRFLRKDARVVLTVHPRPAAAGAAAGSAR

Sequences:

>Translated_458_residues
MIASPLLVAALLTAAPAAAAPPPGDAPEIPYTMFTLGNGLTVILHEDHTAPLVGVHVQYDVGSKDERPGRTGFAHLFEHL
MFQGSAHLPKGEADRLVDAAGGEANGGTSPDSTVYWEQVPSGALEQMLFIEADRMGWMFPTLTQEKLDNQRDVVRNERRQ
SYEMQPYGLVFEKLLANLWDPEFPYHWQTIGTHEDLEAATLADVKQFFERWYGPENAVLAIAGDIDPARTRALVEKWFGP
IPGKARPAHQPPAPKPLAAEQRVSMDDRVQLPRLYLAWQTPRVFAPGDAALDVLSSVLSDGKSARLVKRLVMDEQIAQGV
SAGQMSQALASMYLVVATPKPGIPLERLEREIDEELARIAREPPSAEEVQRAKNKIEAGAVFGLEPVGGFGGRAASLAGY
YVRTGDPGYLAKDLARYRAVTPADVSEAARRFLRKDARVVLTVHPRPAAAGAAAGSAR
>Mature_458_residues
MIASPLLVAALLTAAPAAAAPPPGDAPEIPYTMFTLGNGLTVILHEDHTAPLVGVHVQYDVGSKDERPGRTGFAHLFEHL
MFQGSAHLPKGEADRLVDAAGGEANGGTSPDSTVYWEQVPSGALEQMLFIEADRMGWMFPTLTQEKLDNQRDVVRNERRQ
SYEMQPYGLVFEKLLANLWDPEFPYHWQTIGTHEDLEAATLADVKQFFERWYGPENAVLAIAGDIDPARTRALVEKWFGP
IPGKARPAHQPPAPKPLAAEQRVSMDDRVQLPRLYLAWQTPRVFAPGDAALDVLSSVLSDGKSARLVKRLVMDEQIAQGV
SAGQMSQALASMYLVVATPKPGIPLERLEREIDEELARIAREPPSAEEVQRAKNKIEAGAVFGLEPVGGFGGRAASLAGY
YVRTGDPGYLAKDLARYRAVTPADVSEAARRFLRKDARVVLTVHPRPAAAGAAAGSAR

Specific function: Unknown

COG id: COG0612

COG function: function code R; Predicted Zn-dependent peptidases

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M16 family [H]

Homologues:

Organism=Homo sapiens, GI46593007, Length=311, Percent_Identity=23.1511254019293, Blast_Score=72, Evalue=8e-13,
Organism=Escherichia coli, GI1787770, Length=223, Percent_Identity=26.9058295964126, Blast_Score=78, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6323192, Length=384, Percent_Identity=24.7395833333333, Blast_Score=80, Evalue=7e-16,
Organism=Saccharomyces cerevisiae, GI6323421, Length=269, Percent_Identity=22.6765799256506, Blast_Score=63, Evalue=8e-11,
Organism=Drosophila melanogaster, GI21357875, Length=251, Percent_Identity=27.0916334661355, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24646943, Length=251, Percent_Identity=27.0916334661355, Blast_Score=70, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011249
- InterPro:   IPR011237
- InterPro:   IPR011765
- InterPro:   IPR001431
- InterPro:   IPR007863 [H]

Pfam domain/function: PF00675 Peptidase_M16; PF05193 Peptidase_M16_C [H]

EC number: 3.4.99.- [C]

Molecular weight: Translated: 49788; Mature: 49788

Theoretical pI: Translated: 5.67; Mature: 5.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIASPLLVAALLTAAPAAAAPPPGDAPEIPYTMFTLGNGLTVILHEDHTAPLVGVHVQYD
CCCCHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCCEEEEEECCCCCCEEEEEEEEC
VGSKDERPGRTGFAHLFEHLMFQGSAHLPKGEADRLVDAAGGEANGGTSPDSTVYWEQVP
CCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCEEHHHCC
SGALEQMLFIEADRMGWMFPTLTQEKLDNQRDVVRNERRQSYEMQPYGLVFEKLLANLWD
CHHHHHHHHHHHCCCCCCCCCCCHHHHCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCC
PEFPYHWQTIGTHEDLEAATLADVKQFFERWYGPENAVLAIAGDIDPARTRALVEKWFGP
CCCCCCEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHHCCC
IPGKARPAHQPPAPKPLAAEQRVSMDDRVQLPRLYLAWQTPRVFAPGDAALDVLSSVLSD
CCCCCCCCCCCCCCCCCCHHHHCCCCHHHCCCEEEEEECCCEEECCCHHHHHHHHHHHCC
GKSARLVKRLVMDEQIAQGVSAGQMSQALASMYLVVATPKPGIPLERLEREIDEELARIA
CHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHEEEEEECCCCCCCHHHHHHHHHHHHHHHH
REPPSAEEVQRAKNKIEAGAVFGLEPVGGFGGRAASLAGYYVRTGDPGYLAKDLARYRAV
CCCCCHHHHHHHHHHHHHCEEECCCCCCCCCCCHHHHCEEEEEECCCCHHHHHHHHHHCC
TPADVSEAARRFLRKDARVVLTVHPRPAAAGAAAGSAR
CCCCHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCC
>Mature Secondary Structure
MIASPLLVAALLTAAPAAAAPPPGDAPEIPYTMFTLGNGLTVILHEDHTAPLVGVHVQYD
CCCCHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCCEEEEEECCCCCCEEEEEEEEC
VGSKDERPGRTGFAHLFEHLMFQGSAHLPKGEADRLVDAAGGEANGGTSPDSTVYWEQVP
CCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCEEHHHCC
SGALEQMLFIEADRMGWMFPTLTQEKLDNQRDVVRNERRQSYEMQPYGLVFEKLLANLWD
CHHHHHHHHHHHCCCCCCCCCCCHHHHCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCC
PEFPYHWQTIGTHEDLEAATLADVKQFFERWYGPENAVLAIAGDIDPARTRALVEKWFGP
CCCCCCEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHHCCC
IPGKARPAHQPPAPKPLAAEQRVSMDDRVQLPRLYLAWQTPRVFAPGDAALDVLSSVLSD
CCCCCCCCCCCCCCCCCCHHHHCCCCHHHCCCEEEEEECCCEEECCCHHHHHHHHHHHCC
GKSARLVKRLVMDEQIAQGVSAGQMSQALASMYLVVATPKPGIPLERLEREIDEELARIA
CHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHEEEEEECCCCCCCHHHHHHHHHHHHHHHH
REPPSAEEVQRAKNKIEAGAVFGLEPVGGFGGRAASLAGYYVRTGDPGYLAKDLARYRAV
CCCCCHHHHHHHHHHHHHCEEECCCCCCCCCCCHHHHCEEEEEECCCCHHHHHHHHHHCC
TPADVSEAARRFLRKDARVVLTVHPRPAAAGAAAGSAR
CCCCHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Endopeptidases of unknown catalytic mechanism [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9163424 [H]