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The map label for this gene is lolA [H]

Identifier: 220915227

GI number: 220915227

Start: 118178

End: 118858

Strand: Direct

Name: lolA [H]

Synonym: A2cp1_0106

Alternate gene names: 220915227

Gene position: 118178-118858 (Clockwise)

Preceding gene: 220915224

Following gene: 220915228

Centisome position: 2.35

GC content: 73.86

Gene sequence:

>681_bases
ATGACCTCGAGCTTCCTCCTCGCCCTGCCCGTCGCGCTCGCCCTCGCCGCGTCCGGTCCGGCCCCTGCCGCGGCGGAGCC
CGGCGGCGCCGCGGCGGCGCGCACGCTCGAGGATCCGCGCGCGCTCGCCCGGAAGGTCCAGGCGTTCTACGAGCGGACCC
GCGACCTCGAGGCGCGCTTCCGCCAGGCCTACACCTACGCCGGCTTCGGCCGCCGGCAGACGTCCTCGGGCACGCTGCGC
GTGAAGAAGCCCGGGATGATGCGCTGGGACTACGAGAAGCCGGCGGCGAAGACGGTCGCGGTGAAGGGCTCGCGGCTGGT
GCAGTACGAGCCGGAGGAGAACCAGGCCTACGTGGACGAGGCGTTCGACAGCTCGGCCATGAGCGCGGCGGTGACGTTCC
TGCTCGGCAAGGGCGACCTCCTGCGCGAGTTCGACGTCTCGCTCGACGGCTCGGGCGCGCTGCTGCTCCGGCCGAAGGAG
TCCGATCCGCGGGTCGAGTCCATCGCGCTCACCGTGGCGGCGGACGGGCAGGTGACCGCCACCCGCGTGGTGGACGGCGC
CGGGAACGCGAACGAGATCCGCTTCGAGGACGTCCGGCGGAACGTGGGCCTGCCCGACGCCGCCTTCGAGGTGAAGCTCC
CCCGGGACGTCCGCCGGATCGCGGCGCCGAAGGCCCAGTAG

Upstream 100 bases:

>100_bases
CCTCGCGCTGCTCGCGGCTCGACCGCCTGGCTCGGTCCGGGGATGGATTCACGCGCTCTGAATGCGCCGCCGCGACGGGC
CGTCTGGTATCTAGACCGCC

Downstream 100 bases:

>100_bases
TCGTATCCTGGGGCCCATGTCCGACCCCATCCTCGTCGCGAAGGCCGCCCGCGCGGGCGCCGGCTTCACCGACCTCGCCC
TGCTGCCCCGGCTCGCCAAC

Product: outer membrane lipoprotein carrier protein LolA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 226; Mature: 225

Protein sequence:

>226_residues
MTSSFLLALPVALALAASGPAPAAAEPGGAAAARTLEDPRALARKVQAFYERTRDLEARFRQAYTYAGFGRRQTSSGTLR
VKKPGMMRWDYEKPAAKTVAVKGSRLVQYEPEENQAYVDEAFDSSAMSAAVTFLLGKGDLLREFDVSLDGSGALLLRPKE
SDPRVESIALTVAADGQVTATRVVDGAGNANEIRFEDVRRNVGLPDAAFEVKLPRDVRRIAAPKAQ

Sequences:

>Translated_226_residues
MTSSFLLALPVALALAASGPAPAAAEPGGAAAARTLEDPRALARKVQAFYERTRDLEARFRQAYTYAGFGRRQTSSGTLR
VKKPGMMRWDYEKPAAKTVAVKGSRLVQYEPEENQAYVDEAFDSSAMSAAVTFLLGKGDLLREFDVSLDGSGALLLRPKE
SDPRVESIALTVAADGQVTATRVVDGAGNANEIRFEDVRRNVGLPDAAFEVKLPRDVRRIAAPKAQ
>Mature_225_residues
TSSFLLALPVALALAASGPAPAAAEPGGAAAARTLEDPRALARKVQAFYERTRDLEARFRQAYTYAGFGRRQTSSGTLRV
KKPGMMRWDYEKPAAKTVAVKGSRLVQYEPEENQAYVDEAFDSSAMSAAVTFLLGKGDLLREFDVSLDGSGALLLRPKES
DPRVESIALTVAADGQVTATRVVDGAGNANEIRFEDVRRNVGLPDAAFEVKLPRDVRRIAAPKAQ

Specific function: Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the l

COG id: COG2834

COG function: function code M; Outer membrane lipoprotein-sorting protein

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lolA family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004564
- InterPro:   IPR018323 [H]

Pfam domain/function: PF03548 LolA [H]

EC number: NA

Molecular weight: Translated: 24344; Mature: 24213

Theoretical pI: Translated: 9.61; Mature: 9.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSSFLLALPVALALAASGPAPAAAEPGGAAAARTLEDPRALARKVQAFYERTRDLEARF
CCCCHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
RQAYTYAGFGRRQTSSGTLRVKKPGMMRWDYEKPAAKTVAVKGSRLVQYEPEENQAYVDE
HHHHHHCCCCCCCCCCCEEEEECCCCEEECCCCCCCEEEEECCCEEEEECCCCCCCHHHH
AFDSSAMSAAVTFLLGKGDLLREFDVSLDGSGALLLRPKESDPRVESIALTVAADGQVTA
HHCHHHHHHHHHHHCCCCCHHHHCCCEECCCCEEEEECCCCCCCEEEEEEEEECCCCEEE
TRVVDGAGNANEIRFEDVRRNVGLPDAAFEVKLPRDVRRIAAPKAQ
EEEECCCCCCCCEEHHHHHHCCCCCCCEEEEECCHHHHHHCCCCCC
>Mature Secondary Structure 
TSSFLLALPVALALAASGPAPAAAEPGGAAAARTLEDPRALARKVQAFYERTRDLEARF
CCCHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
RQAYTYAGFGRRQTSSGTLRVKKPGMMRWDYEKPAAKTVAVKGSRLVQYEPEENQAYVDE
HHHHHHCCCCCCCCCCCEEEEECCCCEEECCCCCCCEEEEECCCEEEEECCCCCCCHHHH
AFDSSAMSAAVTFLLGKGDLLREFDVSLDGSGALLLRPKESDPRVESIALTVAADGQVTA
HHCHHHHHHHHHHHCCCCCHHHHCCCEECCCCEEEEECCCCCCCEEEEEEEEECCCCEEE
TRVVDGAGNANEIRFEDVRRNVGLPDAAFEVKLPRDVRRIAAPKAQ
EEEECCCCCCCCEEHHHHHHCCCCCCCEEEEECCHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA