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The map label for this gene is ywbI [H]

Identifier: 220915222

GI number: 220915222

Start: 110793

End: 111728

Strand: Direct

Name: ywbI [H]

Synonym: A2cp1_0101

Alternate gene names: 220915222

Gene position: 110793-111728 (Clockwise)

Preceding gene: 220915219

Following gene: 220915224

Centisome position: 2.2

GC content: 78.42

Gene sequence:

>936_bases
ATGGATCTGCGCGGGCTGGGCGCGTTCGTCGAGGTGGTGCGGCAGGGCGGCTTCACCCGGGCGGCGGCCGCGCTGCACGT
GACGCAGCCGGCGGTGAGCAAGGCGGTGCGGGCGCTGGAGGACGAGATCGGCGTGCCGCTGCTCGAGCGCGGCGCGCGCC
GGACCGTGCCCACCGACGCGGGGCGGGCGGTGCTGGGGCGGGCCGAGGGTGTGCTCGCGGCGGTGCGGGCCATCGAGGAC
GAGGTGGCCGACCTGGGCGCGCTGCGCCGCGGCCGCGCCCGCGTCGGCCTGCCGCCCATGGTGAGCGGCGCGTTCTTCCC
CCCGGTGCTGGCCGCCTACCGCCAGCGCTACCCGGGCATCCAGCTCGAGCTGCGCGAGGAGGGGGCGCGCGAGGTGGAGG
CGCTGGTGGCGTCCGGCGCGCTCGACGTCGGCGTGACGGTGCTCCCGACCGACGAGGCGCGCTTCGAGGCGCTCCCGTTC
GTCCACGACGTGCTCGCGGCGGTGCTCCATCCGGCGAGCCCGCTCGCGCGGCGTCCGCGGCTCGCGCTGGCCGACCTCGC
CGGCACGCCGTTCCTGCTCTACCGGGCCGACTTCGCGCTGCGCGGCCGCATCCTCGATGCCTGCCGCGCGGCCGGGTTCT
TGCCGCAGGTGGCGAGCGAGACCGGGCAGTGGGACTTCATGGCGGCCATGGCCGCGGCGGACGTGGGGGTGGCGCTGCTC
CCCCGCACCATCTGCCGGCGGCTCGACCCGGCGCAGGTGGCGGTGGTGCCGCTCGCCGCGCCGGCCATCGGCTGGAACCT
GGGCCTCGTCTGGCGGCGCGAGGGGACGCTCTCCGCCGCCGCCCGCGCGTTCGTCGAGACCGCGCGCGAGGTGCTGCTCC
CGCGGCGGGCGGCGGGCTACCCGGCCGCGCGCTCCAGGCCGCGCACCAGGAAGTAG

Upstream 100 bases:

>100_bases
GGGGACGGCGCGAGGCATCGGCGGAACCTAGGCGGCGCCCTGCCATGATGGAAGTGAATCTTTGGACTAGGATGCATTCC
GGACAGGCATGGAGGCGCGG

Downstream 100 bases:

>100_bases
ATGGCGTCCGGGTGGTGGAGCACGATGGCGCTGGTCGACTGCTCCGGCACCATCTGGCAGGCGTCGGTGAGCGAGACGCC
GATGGTGCGGACCGGGTCGA

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 311; Mature: 311

Protein sequence:

>311_residues
MDLRGLGAFVEVVRQGGFTRAAAALHVTQPAVSKAVRALEDEIGVPLLERGARRTVPTDAGRAVLGRAEGVLAAVRAIED
EVADLGALRRGRARVGLPPMVSGAFFPPVLAAYRQRYPGIQLELREEGAREVEALVASGALDVGVTVLPTDEARFEALPF
VHDVLAAVLHPASPLARRPRLALADLAGTPFLLYRADFALRGRILDACRAAGFLPQVASETGQWDFMAAMAAADVGVALL
PRTICRRLDPAQVAVVPLAAPAIGWNLGLVWRREGTLSAAARAFVETAREVLLPRRAAGYPAARSRPRTRK

Sequences:

>Translated_311_residues
MDLRGLGAFVEVVRQGGFTRAAAALHVTQPAVSKAVRALEDEIGVPLLERGARRTVPTDAGRAVLGRAEGVLAAVRAIED
EVADLGALRRGRARVGLPPMVSGAFFPPVLAAYRQRYPGIQLELREEGAREVEALVASGALDVGVTVLPTDEARFEALPF
VHDVLAAVLHPASPLARRPRLALADLAGTPFLLYRADFALRGRILDACRAAGFLPQVASETGQWDFMAAMAAADVGVALL
PRTICRRLDPAQVAVVPLAAPAIGWNLGLVWRREGTLSAAARAFVETAREVLLPRRAAGYPAARSRPRTRK
>Mature_311_residues
MDLRGLGAFVEVVRQGGFTRAAAALHVTQPAVSKAVRALEDEIGVPLLERGARRTVPTDAGRAVLGRAEGVLAAVRAIED
EVADLGALRRGRARVGLPPMVSGAFFPPVLAAYRQRYPGIQLELREEGAREVEALVASGALDVGVTVLPTDEARFEALPF
VHDVLAAVLHPASPLARRPRLALADLAGTPFLLYRADFALRGRILDACRAAGFLPQVASETGQWDFMAAMAAADVGVALL
PRTICRRLDPAQVAVVPLAAPAIGWNLGLVWRREGTLSAAARAFVETAREVLLPRRAAGYPAARSRPRTRK

Specific function: Positive Regulatory Protein For The Cyn Operon. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI157672245, Length=285, Percent_Identity=33.6842105263158, Blast_Score=155, Evalue=3e-39,
Organism=Escherichia coli, GI1790399, Length=275, Percent_Identity=29.4545454545455, Blast_Score=122, Evalue=3e-29,
Organism=Escherichia coli, GI1787879, Length=295, Percent_Identity=32.5423728813559, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI145693105, Length=283, Percent_Identity=22.9681978798587, Blast_Score=99, Evalue=2e-22,
Organism=Escherichia coli, GI1788748, Length=290, Percent_Identity=28.6206896551724, Blast_Score=98, Evalue=6e-22,
Organism=Escherichia coli, GI1788481, Length=298, Percent_Identity=28.5234899328859, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1788887, Length=301, Percent_Identity=28.2392026578073, Blast_Score=95, Evalue=5e-21,
Organism=Escherichia coli, GI1787530, Length=267, Percent_Identity=26.9662921348315, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1787806, Length=287, Percent_Identity=27.5261324041812, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1788297, Length=250, Percent_Identity=28, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI1788296, Length=249, Percent_Identity=27.3092369477912, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1790208, Length=248, Percent_Identity=25.8064516129032, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1786401, Length=119, Percent_Identity=36.1344537815126, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI1787601, Length=178, Percent_Identity=26.4044943820225, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI2367136, Length=245, Percent_Identity=25.3061224489796, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI1789204, Length=201, Percent_Identity=28.3582089552239, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1789506, Length=291, Percent_Identity=21.3058419243986, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI145693193, Length=125, Percent_Identity=29.6, Blast_Score=65, Evalue=8e-12,
Organism=Escherichia coli, GI87081904, Length=143, Percent_Identity=30.7692307692308, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1790262, Length=255, Percent_Identity=25.0980392156863, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33144; Mature: 33144

Theoretical pI: Translated: 11.01; Mature: 11.01

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLRGLGAFVEVVRQGGFTRAAAALHVTQPAVSKAVRALEDEIGVPLLERGARRTVPTDA
CCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCCCC
GRAVLGRAEGVLAAVRAIEDEVADLGALRRGRARVGLPPMVSGAFFPPVLAAYRQRYPGI
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCC
QLELREEGAREVEALVASGALDVGVTVLPTDEARFEALPFVHDVLAAVLHPASPLARRPR
EEEEHHHHHHHHHHHHHCCCHHCCEEEEECCCHHHHHHHHHHHHHHHHHCCCCHHHHCCC
LALADLAGTPFLLYRADFALRGRILDACRAAGFLPQVASETGQWDFMAAMAAADVGVALL
HHHHHCCCCCEEEEECCHHHHHHHHHHHHHHCCCHHHHHCCCCHHHHHHHHHHHHHHHHH
PRTICRRLDPAQVAVVPLAAPAIGWNLGLVWRREGTLSAAARAFVETAREVLLPRRAAGY
HHHHHHCCCCCCEEEEEECCCHHCCCEEEEEECCCCHHHHHHHHHHHHHHHHCCCCCCCC
PAARSRPRTRK
CCCCCCCCCCC
>Mature Secondary Structure
MDLRGLGAFVEVVRQGGFTRAAAALHVTQPAVSKAVRALEDEIGVPLLERGARRTVPTDA
CCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCCCC
GRAVLGRAEGVLAAVRAIEDEVADLGALRRGRARVGLPPMVSGAFFPPVLAAYRQRYPGI
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCC
QLELREEGAREVEALVASGALDVGVTVLPTDEARFEALPFVHDVLAAVLHPASPLARRPR
EEEEHHHHHHHHHHHHHCCCHHCCEEEEECCCHHHHHHHHHHHHHHHHHCCCCHHHHCCC
LALADLAGTPFLLYRADFALRGRILDACRAAGFLPQVASETGQWDFMAAMAAADVGVALL
HHHHHCCCCCEEEEECCHHHHHHHHHHHHHHCCCHHHHHCCCCHHHHHHHHHHHHHHHHH
PRTICRRLDPAQVAVVPLAAPAIGWNLGLVWRREGTLSAAARAFVETAREVLLPRRAAGY
HHHHHHCCCCCCEEEEEECCCHHCCCEEEEEECCCCHHHHHHHHHHHHHHHHCCCCCCCC
PAARSRPRTRK
CCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7934828; 9384377 [H]