Click here to switch to the map view.

The map label for this gene is cph1 [H]

Identifier: 220915159

GI number: 220915159

Start: 37974

End: 39617

Strand: Direct

Name: cph1 [H]

Synonym: A2cp1_0036

Alternate gene names: 220915159

Gene position: 37974-39617 (Clockwise)

Preceding gene: 220915155

Following gene: 220915161

Centisome position: 0.76

GC content: 75.91

Gene sequence:

>1644_bases
ATGGCGAGCCCGGGTCCAGACCGTCGGTCGAGGCGGTTCCTGTTCGGCGGTTACGTGGTCGTCGTGGCGAGCTTCATCGC
CGCCTCGGTCTACACCGCGGAGCACATCCGGGAGATCGACGTCGCCTCCGACGAGATCGCCCGCGACGCCATGCCGACGA
TCCGGTGCCTGGCCGAGGCGCGCCACCTCCTCGGCCAGTTCGAGATCGAGTCCGCGGCGTTCGCCGCCGTGCCCGTCACG
CCGGCCGCGCGCGCCGCCGCCGAGGCGCCGCTCCGCGCGCTCGCGGAGCAGGTGGGCGTCTACCTCGCGCTGCCGCTCTT
CCCGGGCGAGCGGCCGTTCTGGGAGGACGTGCGGCGCGGGACCTCCCGGTTCGTGGGCGCGGCGAACCGCATGCTCGGGC
AGGCGGACGCAGGCGACGCGCGGCTCGCGAGGGAAACGTTCCTCCGCGAGGTCCGGCCCGCGGCGGCACACCTGCACGAG
CTCCTGTCCCGCGACCTCGACTTCAACGCCCGCAACGGCAGCCAGCTCGCCGAGCACATCAAGGCCGTGCGCGCGCGAGG
GCTGTGGCTCAGCCTCTCGCTGGGCGTCCTCTGCGGCGGGATCGCGCTGCTGGCCGGGCGGGTCGTCGCCGGTCAGCTCC
GCCGCCACGACGCGCTCGTGAGCGAGCACGAGCGCATGATGGAGGAGCGCGCCGGCGAGCTGGAGGCGTTCGCGGGACGG
GTCGCGCACGACATCATGAACCCGACCGCGAGCGCGCAGCTCGCGATCGACCTCGAGCTCCGGCGCCGGCAGGCGGCGGG
CGAACCCGCGGGCGAGGGCCTCGAGCGCGCGCGGCGCAGCCTCCGGCGGATCCAGACCCTGGTCGCGGGGCTGCTCGGGT
TCGCCCGGGCCGGGGCACGGCCGGAGCCGGGCGCTGCCGCGGACGTCGTCGAGGTCGTCCACGACGTCGTCTCGGGCGCG
GAGGCACGGGCGACCGAGGCGGGCATGACGGTGGGCGCGGAGCTCGTGCCGGGCACCGTCGCCTGCGCGAAGGGCGTCCT
GACCAGCCTGGTGGCGAACCTGGTGGACAACGCCATCAAGTACGCGCGGCGGGACGGGCGGGTCGTGATCCGCGCCGCCC
CGGACGCCGCGGCGATCCGCGTCGAGGTCGAGGACGACGGGCCCGGCCTCCCGCCGGATCTGGGCGACCGGGTCTTCGAG
CCGTACGTCCGCGGCGGCGCCGGGGACGTGCCGGGGCTCGGCCTCGGGCTCGCCACGGTCAAGCGGCTCGCCGAGGCCCA
CGGCGGGCACGTCGGCGTCCGCTCCGAGCCAGGCCGGGGAACCACCTTCTGGTTCGAGCTCCCGCGCGCGGCGGCGGTGA
GCGAGCTGCGTGGATCGCGCGCGGGTAGCCGGCCGGCACACCGGGCGCGGACGTGGCTCAGAGGTCCGCGTAGATCTCGA
GGACGTTGCCGTCGGGATCGCGGAAGAACAAGGTGCGGTGGCCCCAGGGCTGATCCGTCGGCGGCGAGACGATGGGCACC
TCCAGGCGGCGCAGCTCCTCGGCGCAGGCGTCCACCGCGGAGGGCGCCACGCGGAACGCGAGCTGGACCGACAGCGCGCC
CTCGGGCGTGGGCGGGTCGTGGAACAGGCCGCCGCGCTGCGTGA

Upstream 100 bases:

>100_bases
TGCGCCGGACAGGCCCGCTCGCGCGAATGCTGGCGTCGCCTCCGGCGTCCGGCCGGAGCGCACCAGCGACGGAGCTCGGA
CCTCGTCACGAGGCAGGGAC

Downstream 100 bases:

>100_bases
GCACGAGCAGGTTGGAGCCGACGCGGAACTCGACCCAGCCGGGCCCGAGCTCGCGCGCGATGGGGAAACCCATCACCTCC
GCATAGAATCGGCGCATTCG

Product: histidine kinase

Products: NA

Alternate protein names: Bacteriophytochrome cph1; Light-regulated histidine kinase 1 [H]

Number of amino acids: Translated: 547; Mature: 546

Protein sequence:

>547_residues
MASPGPDRRSRRFLFGGYVVVVASFIAASVYTAEHIREIDVASDEIARDAMPTIRCLAEARHLLGQFEIESAAFAAVPVT
PAARAAAEAPLRALAEQVGVYLALPLFPGERPFWEDVRRGTSRFVGAANRMLGQADAGDARLARETFLREVRPAAAHLHE
LLSRDLDFNARNGSQLAEHIKAVRARGLWLSLSLGVLCGGIALLAGRVVAGQLRRHDALVSEHERMMEERAGELEAFAGR
VAHDIMNPTASAQLAIDLELRRRQAAGEPAGEGLERARRSLRRIQTLVAGLLGFARAGARPEPGAAADVVEVVHDVVSGA
EARATEAGMTVGAELVPGTVACAKGVLTSLVANLVDNAIKYARRDGRVVIRAAPDAAAIRVEVEDDGPGLPPDLGDRVFE
PYVRGGAGDVPGLGLGLATVKRLAEAHGGHVGVRSEPGRGTTFWFELPRAAAVSELRGSRAGSRPAHRARTWLRGPRRSR
GRCRRDRGRTRCGGPRADPSAARRWAPPGGAAPRRRRPPRRAPRGTRAGPTARPRAWAGRGTGRRAA

Sequences:

>Translated_547_residues
MASPGPDRRSRRFLFGGYVVVVASFIAASVYTAEHIREIDVASDEIARDAMPTIRCLAEARHLLGQFEIESAAFAAVPVT
PAARAAAEAPLRALAEQVGVYLALPLFPGERPFWEDVRRGTSRFVGAANRMLGQADAGDARLARETFLREVRPAAAHLHE
LLSRDLDFNARNGSQLAEHIKAVRARGLWLSLSLGVLCGGIALLAGRVVAGQLRRHDALVSEHERMMEERAGELEAFAGR
VAHDIMNPTASAQLAIDLELRRRQAAGEPAGEGLERARRSLRRIQTLVAGLLGFARAGARPEPGAAADVVEVVHDVVSGA
EARATEAGMTVGAELVPGTVACAKGVLTSLVANLVDNAIKYARRDGRVVIRAAPDAAAIRVEVEDDGPGLPPDLGDRVFE
PYVRGGAGDVPGLGLGLATVKRLAEAHGGHVGVRSEPGRGTTFWFELPRAAAVSELRGSRAGSRPAHRARTWLRGPRRSR
GRCRRDRGRTRCGGPRADPSAARRWAPPGGAAPRRRRPPRRAPRGTRAGPTARPRAWAGRGTGRRAA
>Mature_546_residues
ASPGPDRRSRRFLFGGYVVVVASFIAASVYTAEHIREIDVASDEIARDAMPTIRCLAEARHLLGQFEIESAAFAAVPVTP
AARAAAEAPLRALAEQVGVYLALPLFPGERPFWEDVRRGTSRFVGAANRMLGQADAGDARLARETFLREVRPAAAHLHEL
LSRDLDFNARNGSQLAEHIKAVRARGLWLSLSLGVLCGGIALLAGRVVAGQLRRHDALVSEHERMMEERAGELEAFAGRV
AHDIMNPTASAQLAIDLELRRRQAAGEPAGEGLERARRSLRRIQTLVAGLLGFARAGARPEPGAAADVVEVVHDVVSGAE
ARATEAGMTVGAELVPGTVACAKGVLTSLVANLVDNAIKYARRDGRVVIRAAPDAAAIRVEVEDDGPGLPPDLGDRVFEP
YVRGGAGDVPGLGLGLATVKRLAEAHGGHVGVRSEPGRGTTFWFELPRAAAVSELRGSRAGSRPAHRARTWLRGPRRSRG
RCRRDRGRTRCGGPRADPSAARRWAPPGGAAPRRRRPPRRAPRGTRAGPTARPRAWAGRGTGRRAA

Specific function: Regulatory photoreceptor which exists in two forms that are reversibly interconvertible by light:the R form that absorbs maximally in the red region of the spectrum and the FR form that absorbs maximally in the far-red region. Has also a slight blue shift

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1786912, Length=256, Percent_Identity=28.515625, Blast_Score=83, Evalue=4e-17,
Organism=Escherichia coli, GI1790436, Length=240, Percent_Identity=28.75, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1789808, Length=213, Percent_Identity=26.7605633802817, Blast_Score=76, Evalue=6e-15,
Organism=Escherichia coli, GI1790346, Length=269, Percent_Identity=25.6505576208178, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI48994928, Length=251, Percent_Identity=27.0916334661355, Blast_Score=72, Evalue=7e-14,
Organism=Escherichia coli, GI1789149, Length=375, Percent_Identity=22.6666666666667, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1788549, Length=224, Percent_Identity=26.3392857142857, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI87082128, Length=237, Percent_Identity=26.5822784810127, Blast_Score=70, Evalue=4e-13,
Organism=Escherichia coli, GI1786600, Length=227, Percent_Identity=25.9911894273128, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI145693157, Length=109, Percent_Identity=33.9449541284404, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI87081816, Length=99, Percent_Identity=36.3636363636364, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1790551, Length=225, Percent_Identity=26.6666666666667, Blast_Score=65, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003018
- InterPro:   IPR000014
- InterPro:   IPR013654
- InterPro:   IPR016132
- InterPro:   IPR001294
- InterPro:   IPR013515
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF01590 GAF; PF02518 HATPase_c; PF00512 HisKA; PF08446 PAS_2; PF00360 Phytochrome [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 58440; Mature: 58309

Theoretical pI: Translated: 11.71; Mature: 11.71

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASPGPDRRSRRFLFGGYVVVVASFIAASVYTAEHIREIDVASDEIARDAMPTIRCLAEA
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
RHLLGQFEIESAAFAAVPVTPAARAAAEAPLRALAEQVGVYLALPLFPGERPFWEDVRRG
HHHHHHHHHCCHHEEECCCCHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCHHHHHHHH
TSRFVGAANRMLGQADAGDARLARETFLREVRPAAAHLHELLSRDLDFNARNGSQLAEHI
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHH
KAVRARGLWLSLSLGVLCGGIALLAGRVVAGQLRRHDALVSEHERMMEERAGELEAFAGR
HHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VAHDIMNPTASAQLAIDLELRRRQAAGEPAGEGLERARRSLRRIQTLVAGLLGFARAGAR
HHHHHHCCCCCCEEEEEHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
PEPGAAADVVEVVHDVVSGAEARATEAGMTVGAELVPGTVACAKGVLTSLVANLVDNAIK
CCCCHHHHHHHHHHHHHCCCHHHHHHHCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHH
YARRDGRVVIRAAPDAAAIRVEVEDDGPGLPPDLGDRVFEPYVRGGAGDVPGLGLGLATV
HHHCCCCEEEEECCCCEEEEEEECCCCCCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHH
KRLAEAHGGHVGVRSEPGRGTTFWFELPRAAAVSELRGSRAGSRPAHRARTWLRGPRRSR
HHHHHHCCCEECCCCCCCCCCEEEEECCHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCHH
GRCRRDRGRTRCGGPRADPSAARRWAPPGGAAPRRRRPPRRAPRGTRAGPTARPRAWAGR
HHHHHHCCCCCCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
GTGRRAA
CCCCCCC
>Mature Secondary Structure 
ASPGPDRRSRRFLFGGYVVVVASFIAASVYTAEHIREIDVASDEIARDAMPTIRCLAEA
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
RHLLGQFEIESAAFAAVPVTPAARAAAEAPLRALAEQVGVYLALPLFPGERPFWEDVRRG
HHHHHHHHHCCHHEEECCCCHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCHHHHHHHH
TSRFVGAANRMLGQADAGDARLARETFLREVRPAAAHLHELLSRDLDFNARNGSQLAEHI
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHH
KAVRARGLWLSLSLGVLCGGIALLAGRVVAGQLRRHDALVSEHERMMEERAGELEAFAGR
HHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VAHDIMNPTASAQLAIDLELRRRQAAGEPAGEGLERARRSLRRIQTLVAGLLGFARAGAR
HHHHHHCCCCCCEEEEEHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
PEPGAAADVVEVVHDVVSGAEARATEAGMTVGAELVPGTVACAKGVLTSLVANLVDNAIK
CCCCHHHHHHHHHHHHHCCCHHHHHHHCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHH
YARRDGRVVIRAAPDAAAIRVEVEDDGPGLPPDLGDRVFEPYVRGGAGDVPGLGLGLATV
HHHCCCCEEEEECCCCEEEEEEECCCCCCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHH
KRLAEAHGGHVGVRSEPGRGTTFWFELPRAAAVSELRGSRAGSRPAHRARTWLRGPRRSR
HHHHHHCCCEECCCCCCCCCCEEEEECCHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCHH
GRCRRDRGRTRCGGPRADPSAARRWAPPGGAAPRRRRPPRRAPRGTRAGPTARPRAWAGR
HHHHHHCCCCCCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
GTGRRAA
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231; 9109482; 9278513; 10828948 [H]