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The map label for this gene is lspA [H]

Identifier: 220915136

GI number: 220915136

Start: 17940

End: 18560

Strand: Direct

Name: lspA [H]

Synonym: A2cp1_0013

Alternate gene names: 220915136

Gene position: 17940-18560 (Clockwise)

Preceding gene: 220915135

Following gene: 220915137

Centisome position: 0.36

GC content: 71.18

Gene sequence:

>621_bases
ATGCGGCGACCGGTCTCGAAGTGGGCGCTCCTCGCCCTCCTGTTCGCGGCGCTCCTCGCCGCCGACCAGTGGACGAAGTA
CCTGGCGGTGGAGCGCCTCACCGTGGTGTTCGAGCGCGGCGGCGACGAGACGCTCGCGGAGCGGGTCCGCGGCTTCTACA
CGTACCGTCACCTCGAGCCGCTCTCGACCGAGCCGTACTACGTGTGGCGGCCGGTGTGGCGGATGAACTACGTGGAGAAC
CCGGGCGCCGCCTGGGGCCTGTTCCGCGGCCACTCGCAGCTCTTCCGGAACGCGTTCTTCACGCTGGTTTCGCTCGCCGC
GGTGGCGTTCATCCTCCACTACTACCGCAAGCTCCGGCAGGATCAGCGCTACCTGCAGGTGGCGCTCGCGCTGGTGCTGG
CGGGCGCGGTGGGCAACTTCGTGGACCGCCTGGCCCGCCGGTACGTCATCGACTTCGTCGAGTGGTACTGGTGGAACCGG
CCCGACCTCCGCTGGCCCACCTTCAACGTGGCCGACTCGCTCATCGTGGTGGGCGTCGCGATGCTCGTCCTGCACCCCGG
CTCGAAGCGCGAGGCGGCGCGCGCGCCGGAGCGGCGCGGCGCCGCGGCCGAGCGCGTGTAG

Upstream 100 bases:

>100_bases
CACCGGGCGTGAAGTGCGAGCGGTGCTGGATCTACGCCGAGGACGTGGGCCGGGACGCCGCCCACCCGACGCTGTGCGCG
AAGTGCGTGGGCAACCTGTG

Downstream 100 bases:

>100_bases
GCCTCGCCCCGCATGCTCCCCGTCCTCTTCCGGATCCCGCTGCCCGGCGGCGCCTCGCTGCCGCTCCACACCTACGGCCT
GCTCATCGCGGTCGGCTTCA

Product: lipoprotein signal peptidase

Products: NA

Alternate protein names: Prolipoprotein signal peptidase; Signal peptidase II; SPase II [H]

Number of amino acids: Translated: 206; Mature: 206

Protein sequence:

>206_residues
MRRPVSKWALLALLFAALLAADQWTKYLAVERLTVVFERGGDETLAERVRGFYTYRHLEPLSTEPYYVWRPVWRMNYVEN
PGAAWGLFRGHSQLFRNAFFTLVSLAAVAFILHYYRKLRQDQRYLQVALALVLAGAVGNFVDRLARRYVIDFVEWYWWNR
PDLRWPTFNVADSLIVVGVAMLVLHPGSKREAARAPERRGAAAERV

Sequences:

>Translated_206_residues
MRRPVSKWALLALLFAALLAADQWTKYLAVERLTVVFERGGDETLAERVRGFYTYRHLEPLSTEPYYVWRPVWRMNYVEN
PGAAWGLFRGHSQLFRNAFFTLVSLAAVAFILHYYRKLRQDQRYLQVALALVLAGAVGNFVDRLARRYVIDFVEWYWWNR
PDLRWPTFNVADSLIVVGVAMLVLHPGSKREAARAPERRGAAAERV
>Mature_206_residues
MRRPVSKWALLALLFAALLAADQWTKYLAVERLTVVFERGGDETLAERVRGFYTYRHLEPLSTEPYYVWRPVWRMNYVEN
PGAAWGLFRGHSQLFRNAFFTLVSLAAVAFILHYYRKLRQDQRYLQVALALVLAGAVGNFVDRLARRYVIDFVEWYWWNR
PDLRWPTFNVADSLIVVGVAMLVLHPGSKREAARAPERRGAAAERV

Specific function: This protein specifically catalyzes the removal of signal peptides from prolipoproteins [H]

COG id: COG0597

COG function: function code MU; Lipoprotein signal peptidase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase A8 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001872 [H]

Pfam domain/function: PF01252 Peptidase_A8 [H]

EC number: =3.4.23.36 [H]

Molecular weight: Translated: 23976; Mature: 23976

Theoretical pI: Translated: 10.45; Mature: 10.45

Prosite motif: PS00855 SPASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRPVSKWALLALLFAALLAADQWTKYLAVERLTVVFERGGDETLAERVRGFYTYRHLEP
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCC
LSTEPYYVWRPVWRMNYVENPGAAWGLFRGHSQLFRNAFFTLVSLAAVAFILHYYRKLRQ
CCCCCEEEECHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DQRYLQVALALVLAGAVGNFVDRLARRYVIDFVEWYWWNRPDLRWPTFNVADSLIVVGVA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHH
MLVLHPGSKREAARAPERRGAAAERV
HHHHCCCCCHHHHCCCHHCCCCCCCC
>Mature Secondary Structure
MRRPVSKWALLALLFAALLAADQWTKYLAVERLTVVFERGGDETLAERVRGFYTYRHLEP
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCC
LSTEPYYVWRPVWRMNYVENPGAAWGLFRGHSQLFRNAFFTLVSLAAVAFILHYYRKLRQ
CCCCCEEEECHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DQRYLQVALALVLAGAVGNFVDRLARRYVIDFVEWYWWNRPDLRWPTFNVADSLIVVGVA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHH
MLVLHPGSKREAARAPERRGAAAERV
HHHHCCCCCHHHHCCCHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA