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The map label for this gene is aaeR [H]

Identifier: 220915073

GI number: 220915073

Start: 449618

End: 450523

Strand: Reverse

Name: aaeR [H]

Synonym: Mnod_8248

Alternate gene names: 220915073

Gene position: 450523-449618 (Counterclockwise)

Preceding gene: NA

Following gene: 220915067

Centisome position: 98.35

GC content: 70.2

Gene sequence:

>906_bases
GTGCGGAACCTGACGGATCTCTACTACTTCGCCAAGGTGGCCGAGCATGGCGGCTTCTCGGCCGCCAGTCGGGTGCTCGA
CCAGCCGAAATCGACGCTGAGCCGCCGCATCGCAGCGCTGGAACGCGACCTCGGGGTCCGGCTGATCCAGCGCACCAACA
ACCGCTTCGCGCTGACGGAGATCGGCAGCGCCTATGTGGCGCATTGCCAGGCGATGATCGCCGAGGCGCAGGCGGCGCAG
CAGGTCGTGGAGAACTGGCGCGCTGAGCCGACCGGGACGCTGCGCGTCAGCTGCCCGATCGCGCTCGCCCAGGCCCGCGT
CTCCGAGATCGTCGCGCGCTTCATGATCGCCCATCCGGGCGTTTCCGTCCGCTTCATCGCCACGAACCGGACGGTCGACC
TGATCGAGGAGGGCATCGACGTGGCGTTGCGGGTGCGCTTCCCGCCGCTCGAAGAATCGGATCTCGTCATGCGGGTGCTG
TCGGACAGCACCCAGGCGATCGTGGGGGCGCCGGCCCTCCTCGACCGCCTCGGCCGTCCCTCCGCCCCGGAGGCTCTGGC
GGGTATGGATGCGCTCGACCTGATCCGCCAGGACCGGAACCATGTCTGGCACCTGACGCACCAGGACGGGCGCAGCGTCG
CGATTCCCTTTGCGCCGCGCCTTGTGTCGGACGACATGCTCACCCTGCGCCAGGCCGCCCGGGAGGGGGTCGGGGTCGTC
CGCCTGCCCACCTATCTGGTGCAGGCGGCCCTGGACAAGGGCGACCTCGAAGCCGTGCTTCCGGCCTGGACGCCGCGCAG
CGGCATCATCCACGCCGTCCTGCCGTCCCGTCGCGGTCTCGCGCGGGCCACGCGCCTGTTCGTCGACAGCCTGGTCGAGG
GTTTCAGGCAGCCCGCACGCAGATAG

Upstream 100 bases:

>100_bases
TCCTCCGGGGGGTTACGTCGGTGCCCGAAATCTACGCGCGCCGGATCTTGCCGGGAGGCAGCCGGAATGGCACGGGTCGT
TCCAGAATTGGGACGTGACC

Downstream 100 bases:

>100_bases
GGGGACCGTGATCCCGGCCGAGGCCGTGCGGGTTCGCCCGAGCCGGACGGTCCCGCGCCGCAGCATCGTGATGCGGCGCT
CCAGCGCGCTCCCCGCCGCA

Product: transcriptional regulator, LysR family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 301; Mature: 301

Protein sequence:

>301_residues
MRNLTDLYYFAKVAEHGGFSAASRVLDQPKSTLSRRIAALERDLGVRLIQRTNNRFALTEIGSAYVAHCQAMIAEAQAAQ
QVVENWRAEPTGTLRVSCPIALAQARVSEIVARFMIAHPGVSVRFIATNRTVDLIEEGIDVALRVRFPPLEESDLVMRVL
SDSTQAIVGAPALLDRLGRPSAPEALAGMDALDLIRQDRNHVWHLTHQDGRSVAIPFAPRLVSDDMLTLRQAAREGVGVV
RLPTYLVQAALDKGDLEAVLPAWTPRSGIIHAVLPSRRGLARATRLFVDSLVEGFRQPARR

Sequences:

>Translated_301_residues
MRNLTDLYYFAKVAEHGGFSAASRVLDQPKSTLSRRIAALERDLGVRLIQRTNNRFALTEIGSAYVAHCQAMIAEAQAAQ
QVVENWRAEPTGTLRVSCPIALAQARVSEIVARFMIAHPGVSVRFIATNRTVDLIEEGIDVALRVRFPPLEESDLVMRVL
SDSTQAIVGAPALLDRLGRPSAPEALAGMDALDLIRQDRNHVWHLTHQDGRSVAIPFAPRLVSDDMLTLRQAAREGVGVV
RLPTYLVQAALDKGDLEAVLPAWTPRSGIIHAVLPSRRGLARATRLFVDSLVEGFRQPARR
>Mature_301_residues
MRNLTDLYYFAKVAEHGGFSAASRVLDQPKSTLSRRIAALERDLGVRLIQRTNNRFALTEIGSAYVAHCQAMIAEAQAAQ
QVVENWRAEPTGTLRVSCPIALAQARVSEIVARFMIAHPGVSVRFIATNRTVDLIEEGIDVALRVRFPPLEESDLVMRVL
SDSTQAIVGAPALLDRLGRPSAPEALAGMDALDLIRQDRNHVWHLTHQDGRSVAIPFAPRLVSDDMLTLRQAAREGVGVV
RLPTYLVQAALDKGDLEAVLPAWTPRSGIIHAVLPSRRGLARATRLFVDSLVEGFRQPARR

Specific function: Activates transcription of the aaeXAB operon [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789639, Length=296, Percent_Identity=29.3918918918919, Blast_Score=137, Evalue=1e-33,
Organism=Escherichia coli, GI1786401, Length=293, Percent_Identity=28.6689419795222, Blast_Score=122, Evalue=3e-29,
Organism=Escherichia coli, GI145693193, Length=299, Percent_Identity=28.7625418060201, Blast_Score=114, Evalue=5e-27,
Organism=Escherichia coli, GI1787128, Length=293, Percent_Identity=26.2798634812287, Blast_Score=105, Evalue=4e-24,
Organism=Escherichia coli, GI1789440, Length=287, Percent_Identity=26.8292682926829, Blast_Score=102, Evalue=4e-23,
Organism=Escherichia coli, GI87081978, Length=298, Percent_Identity=27.8523489932886, Blast_Score=95, Evalue=4e-21,
Organism=Escherichia coli, GI1787589, Length=291, Percent_Identity=26.1168384879725, Blast_Score=94, Evalue=7e-21,
Organism=Escherichia coli, GI1787601, Length=128, Percent_Identity=28.125, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33101; Mature: 33101

Theoretical pI: Translated: 9.95; Mature: 9.95

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRNLTDLYYFAKVAEHGGFSAASRVLDQPKSTLSRRIAALERDLGVRLIQRTNNRFALTE
CCCHHHHHHHHHHHHCCCHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEHH
IGSAYVAHCQAMIAEAQAAQQVVENWRAEPTGTLRVSCPIALAQARVSEIVARFMIAHPG
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHCCC
VSVRFIATNRTVDLIEEGIDVALRVRFPPLEESDLVMRVLSDSTQAIVGAPALLDRLGRP
CEEEEEEECCHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHCCCHHHHCCHHHHHHCCCC
SAPEALAGMDALDLIRQDRNHVWHLTHQDGRSVAIPFAPRLVSDDMLTLRQAAREGVGVV
CCCHHHHCCHHHHHHHHCCCCEEEEEECCCCEEECCCCCCHHHHHHHHHHHHHHHCCCEE
RLPTYLVQAALDKGDLEAVLPAWTPRSGIIHAVLPSRRGLARATRLFVDSLVEGFRQPAR
HHHHHHHHHHHCCCCCCEECCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCC
R
C
>Mature Secondary Structure
MRNLTDLYYFAKVAEHGGFSAASRVLDQPKSTLSRRIAALERDLGVRLIQRTNNRFALTE
CCCHHHHHHHHHHHHCCCHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEHH
IGSAYVAHCQAMIAEAQAAQQVVENWRAEPTGTLRVSCPIALAQARVSEIVARFMIAHPG
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHCCC
VSVRFIATNRTVDLIEEGIDVALRVRFPPLEESDLVMRVLSDSTQAIVGAPALLDRLGRP
CEEEEEEECCHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHCCCHHHHCCHHHHHHCCCC
SAPEALAGMDALDLIRQDRNHVWHLTHQDGRSVAIPFAPRLVSDDMLTLRQAAREGVGVV
CCCHHHHCCHHHHHHHHCCCCEEEEEECCCCEEECCCCCCHHHHHHHHHHHHHHHCCCEE
RLPTYLVQAALDKGDLEAVLPAWTPRSGIIHAVLPSRRGLARATRLFVDSLVEGFRQPAR
HHHHHHHHHHHCCCCCCEECCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCC
R
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]