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The map label for this gene is cusB [H]

Identifier: 220914842

GI number: 220914842

Start: 207730

End: 209190

Strand: Reverse

Name: cusB [H]

Synonym: Mnod_7982

Alternate gene names: 220914842

Gene position: 209190-207730 (Counterclockwise)

Preceding gene: 220914843

Following gene: 220914841

Centisome position: 45.67

GC content: 71.25

Gene sequence:

>1461_bases
ATGAGCAGGTCGGCCTGGCTGGCCGGGACCCTCGCCGCATTGGCGGCGGGGGGTGCCGGCTATTGGGCCGGGCACGGGAG
CAATCCCGCGCCCGCGCTCCTCGACCGTGCCCGCACGGAATTCGCCCTTTGGCTGCCGCCGGCCGCGGCCCCGCCCCCGG
CAGCACCCGCACCCGCGCCGCGCGGCCCGGTGGTCTACTACCAGGATCCGGATGGCAGGCCGGCCTACAGCCTGGAGCCC
ACCCGCACGCCGGACGGCCGGGCGTTCCGGCCCGTGCACGCCAGCGAGGACATCCATTTCGAGACGGACGACATGGAGGC
CGATGGCCCCGCCGATCGTCCGCCGGACGCCCCGGCCGGTGGGGAGAAAAAACGGATCCTCTACTACCGCAACCCGATGG
GCCTGCCGGACACCTCGCCGGTGCCGAAGAAGGACTCGATGGGGATGGACTACCTGCCCGTCTATGCGGGCGAGGACACG
GACGGCAGCGCCGTCACCATCTCGCCGGGCAAGATCCAGCGCACTGGCGTGCGCTCTGAGACGATCGAGCGCCGCGTGCT
GTCGCAACCGGTCCGCGCGCCCGGCACCGTCGAGGAGGATGAGCGGCGGGTTTCGGTGATCGCCACGCGGACGGACGCCT
TCGTCGAGACGGTCGAGAGCGTCACCACCGGTGACCATGTCCACAAGGGCCAGCCGCTGCTGCGCCTGTTCTCGCCCGAG
ATCAACGCCGCCGCGGCGCAGTATCTGTCGGCCATCGGCTACGAGGGCGCTCGCCGCCGCCTGGAAAACCTGGCGATCCC
GCCCGAGGTGATCGATGAGATCGAGCGAACCCGCAAGGTCCCGGCGGCGATCACCTGGACGTCGCCGCGCGACGGCGTGG
TGGTCGAGCGCAATGTTTCGGACGGCATGCGCGCGCAGGCCGGCGCCGTGCTGTTCCGAATCGTCGATCACAGCCGGGTC
TGGGTCCTGGCCGATGTGCCCGAGCGCGATCTGGCTGCCGTGGCCGAGGGCCAGCGCGCCATTGTGCGCGCCCGTGCGTT
CCCGGACCGAGCGTTCACCGGCACGGTGACGCGGATCTATCCGCACCTGTCGACGGGCACGCGCACCGCGCGCCTGCGCA
TCGAGCTGCCCAACCCCAACGGCGACCTGCGCCCGGCCATGTACGCGGATGTCGAGATTACCACCGGCAGCGACGCACCG
GTGGTCGCCGTACCCGATGATGCGGTGATCGACACCGGCACGCGCCAGGTGGTCATTCTCGACAAGGGCGAGGGACGATT
CGAGCCGCGCGAGGTCAAGGTCGGCCGCCGAGGCGACGGCTATGTGGAGATCCGCGAGGGTCTGCAGGCCGGGGCCCAGG
TGGTGACCGCGGCCAACTTCCTGATCGACGCCGAAAGCAACCTCAAAGCCGCGCTGCAGAGCATGGCCGCGGCCACTCCC
GCCCCGGAGGCCGCCCGATGA

Upstream 100 bases:

>100_bases
CCAAGCTCTCGATGGCCGGCGGCTGGCGCCTGTCGCTCGGAGCCAAGGTCCAGGGCGAGACCGGCACGGTCGAAAACAAG
CTGGTGCTCAAGGCTGTCAA

Downstream 100 bases:

>100_bases
TCGCGCGCCTGATCGGCTGGTCCGCCCGCAACCTGGTGCTGGTGCTGATCGGCACCGTGTTTGCCGTCGCCGCCGGCCTC
CATGCCCTGCGCACGCTGCC

Product: efflux transporter, RND family, MFP subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 486; Mature: 485

Protein sequence:

>486_residues
MSRSAWLAGTLAALAAGGAGYWAGHGSNPAPALLDRARTEFALWLPPAAAPPPAAPAPAPRGPVVYYQDPDGRPAYSLEP
TRTPDGRAFRPVHASEDIHFETDDMEADGPADRPPDAPAGGEKKRILYYRNPMGLPDTSPVPKKDSMGMDYLPVYAGEDT
DGSAVTISPGKIQRTGVRSETIERRVLSQPVRAPGTVEEDERRVSVIATRTDAFVETVESVTTGDHVHKGQPLLRLFSPE
INAAAAQYLSAIGYEGARRRLENLAIPPEVIDEIERTRKVPAAITWTSPRDGVVVERNVSDGMRAQAGAVLFRIVDHSRV
WVLADVPERDLAAVAEGQRAIVRARAFPDRAFTGTVTRIYPHLSTGTRTARLRIELPNPNGDLRPAMYADVEITTGSDAP
VVAVPDDAVIDTGTRQVVILDKGEGRFEPREVKVGRRGDGYVEIREGLQAGAQVVTAANFLIDAESNLKAALQSMAAATP
APEAAR

Sequences:

>Translated_486_residues
MSRSAWLAGTLAALAAGGAGYWAGHGSNPAPALLDRARTEFALWLPPAAAPPPAAPAPAPRGPVVYYQDPDGRPAYSLEP
TRTPDGRAFRPVHASEDIHFETDDMEADGPADRPPDAPAGGEKKRILYYRNPMGLPDTSPVPKKDSMGMDYLPVYAGEDT
DGSAVTISPGKIQRTGVRSETIERRVLSQPVRAPGTVEEDERRVSVIATRTDAFVETVESVTTGDHVHKGQPLLRLFSPE
INAAAAQYLSAIGYEGARRRLENLAIPPEVIDEIERTRKVPAAITWTSPRDGVVVERNVSDGMRAQAGAVLFRIVDHSRV
WVLADVPERDLAAVAEGQRAIVRARAFPDRAFTGTVTRIYPHLSTGTRTARLRIELPNPNGDLRPAMYADVEITTGSDAP
VVAVPDDAVIDTGTRQVVILDKGEGRFEPREVKVGRRGDGYVEIREGLQAGAQVVTAANFLIDAESNLKAALQSMAAATP
APEAAR
>Mature_485_residues
SRSAWLAGTLAALAAGGAGYWAGHGSNPAPALLDRARTEFALWLPPAAAPPPAAPAPAPRGPVVYYQDPDGRPAYSLEPT
RTPDGRAFRPVHASEDIHFETDDMEADGPADRPPDAPAGGEKKRILYYRNPMGLPDTSPVPKKDSMGMDYLPVYAGEDTD
GSAVTISPGKIQRTGVRSETIERRVLSQPVRAPGTVEEDERRVSVIATRTDAFVETVESVTTGDHVHKGQPLLRLFSPEI
NAAAAQYLSAIGYEGARRRLENLAIPPEVIDEIERTRKVPAAITWTSPRDGVVVERNVSDGMRAQAGAVLFRIVDHSRVW
VLADVPERDLAAVAEGQRAIVRARAFPDRAFTGTVTRIYPHLSTGTRTARLRIELPNPNGDLRPAMYADVEITTGSDAPV
VAVPDDAVIDTGTRQVVILDKGEGRFEPREVKVGRRGDGYVEIREGLQAGAQVVTAANFLIDAESNLKAALQSMAAATPA
PEAAR

Specific function: Part of a cation efflux system that mediates resistance to copper and silver [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI1786787, Length=371, Percent_Identity=32.6145552560647, Blast_Score=189, Evalue=5e-49,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006143 [H]

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 52211; Mature: 52080

Theoretical pI: Translated: 5.41; Mature: 5.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRSAWLAGTLAALAAGGAGYWAGHGSNPAPALLDRARTEFALWLPPAAAPPPAAPAPAP
CCCCHHHHHHHHHHHCCCCCEECCCCCCCCHHHHHHCCCCEEEEECCCCCCCCCCCCCCC
RGPVVYYQDPDGRPAYSLEPTRTPDGRAFRPVHASEDIHFETDDMEADGPADRPPDAPAG
CCCEEEEECCCCCCCCCCCCCCCCCCCEECCCCCCCCCEEECCCCCCCCCCCCCCCCCCC
GEKKRILYYRNPMGLPDTSPVPKKDSMGMDYLPVYAGEDTDGSAVTISPGKIQRTGVRSE
CCCCEEEEEECCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCEEEECCCCEEECCCHHH
TIERRVLSQPVRAPGTVEEDERRVSVIATRTDAFVETVESVTTGDHVHKGQPLLRLFSPE
HHHHHHHHCCCCCCCCCCCCCCEEEEEEECHHHHHHHHHHHHCCCCCCCCCCEEEECCCC
INAAAAQYLSAIGYEGARRRLENLAIPPEVIDEIERTRKVPAAITWTSPRDGVVVERNVS
HHHHHHHHHHHHCCHHHHHHHHHCCCCHHHHHHHHHHHCCCEEEEECCCCCCEEEEECCC
DGMRAQAGAVLFRIVDHSRVWVLADVPERDLAAVAEGQRAIVRARAFPDRAFTGTVTRIY
CCCHHHHCEEEEEEECCCEEEEEECCCCHHHHHHHCCCCEEEEECCCCCCCCCCCEEEEE
PHLSTGTRTARLRIELPNPNGDLRPAMYADVEITTGSDAPVVAVPDDAVIDTGTRQVVIL
ECCCCCCEEEEEEEEECCCCCCCCCEEEEEEEEECCCCCCEEECCCCCEECCCCCEEEEE
DKGEGRFEPREVKVGRRGDGYVEIREGLQAGAQVVTAANFLIDAESNLKAALQSMAAATP
ECCCCCCCHHEEECCCCCCCCHHHHHHHHHHHHHEEEEEEEEECCCHHHHHHHHHHHCCC
APEAAR
CCCCCC
>Mature Secondary Structure 
SRSAWLAGTLAALAAGGAGYWAGHGSNPAPALLDRARTEFALWLPPAAAPPPAAPAPAP
CCCHHHHHHHHHHHCCCCCEECCCCCCCCHHHHHHCCCCEEEEECCCCCCCCCCCCCCC
RGPVVYYQDPDGRPAYSLEPTRTPDGRAFRPVHASEDIHFETDDMEADGPADRPPDAPAG
CCCEEEEECCCCCCCCCCCCCCCCCCCEECCCCCCCCCEEECCCCCCCCCCCCCCCCCCC
GEKKRILYYRNPMGLPDTSPVPKKDSMGMDYLPVYAGEDTDGSAVTISPGKIQRTGVRSE
CCCCEEEEEECCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCEEEECCCCEEECCCHHH
TIERRVLSQPVRAPGTVEEDERRVSVIATRTDAFVETVESVTTGDHVHKGQPLLRLFSPE
HHHHHHHHCCCCCCCCCCCCCCEEEEEEECHHHHHHHHHHHHCCCCCCCCCCEEEECCCC
INAAAAQYLSAIGYEGARRRLENLAIPPEVIDEIERTRKVPAAITWTSPRDGVVVERNVS
HHHHHHHHHHHHCCHHHHHHHHHCCCCHHHHHHHHHHHCCCEEEEECCCCCCEEEEECCC
DGMRAQAGAVLFRIVDHSRVWVLADVPERDLAAVAEGQRAIVRARAFPDRAFTGTVTRIY
CCCHHHHCEEEEEEECCCEEEEEECCCCHHHHHHHCCCCEEEEECCCCCCCCCCCEEEEE
PHLSTGTRTARLRIELPNPNGDLRPAMYADVEITTGSDAPVVAVPDDAVIDTGTRQVVIL
ECCCCCCEEEEEEEEECCCCCCCCCEEEEEEEEECCCCCCEEECCCCCEECCCCCEEEEE
DKGEGRFEPREVKVGRRGDGYVEIREGLQAGAQVVTAANFLIDAESNLKAALQSMAAATP
ECCCCCCCHHEEECCCCCCCCHHHHHHHHHHHHHEEEEEEEEECCCHHHHHHHHHHHCCC
APEAAR
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]