| Definition | Methylobacterium nodulans ORS 2060 plasmid pMNOD02, complete sequence. |
|---|---|
| Accession | NC_011887 |
| Length | 458,070 |
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The map label for this gene is ifcA [H]
Identifier: 220914809
GI number: 220914809
Start: 169952
End: 171322
Strand: Reverse
Name: ifcA [H]
Synonym: Mnod_7946
Alternate gene names: 220914809
Gene position: 171322-169952 (Counterclockwise)
Preceding gene: 220914810
Following gene: 220914808
Centisome position: 37.4
GC content: 73.16
Gene sequence:
>1371_bases GTGAGCGAGGACGATCTCGATATCCTGGTGATCGGTGCCGGCGCCTGCGGGCTCGCTGCGGCGGTGGCCGGGCACGATGC CGGCGCGAGCGTGGCGGTGATCGAGAAGCAGGAGCGGCCCGGCGGCAACTCCTCGCTCTCGACCGGCTCGGTGCCGGCGG CGGGCAGCCGTTTCCAGCGCGAGGCCGGCATCGACGACGATCCGGCGCGCATGGTCCGCGACCTGATGGCGATCGCCCGC GAGACCGACGACCGCGCCCTGGTGGAGCGTCTCGCCGGCGTCTCGGCCGAGACCGTGGAATGGCTCGTTGACACGGTCGG GGCGCGGCTCGCGCTCATCACCGCCTACAAGCACATTGGCCATTCGGTGCCGCGCCTGCACGCCCCGGTCTCACGGCGGG GCCAGGACCTCGTCGACGATCTCGTCGCCGCGGCGGAGCGGCGCGGCATCCCGATCGCCGTCGGCAACGGGGCGACCGAC CTCCTCGTGGAGGACGGCGCGGTCCGCGGCGCGATCGTCAGCGTCGAGGGCGAGCGCACGGAGATCCGGGCAGGCAAGAC GATCCTCGCGCTCAACGGCTTCGCCGCGAACCCGGACCTCGTGCGGCGCTTCTGCCCCGAAATCGCCGGAGCGCAGTATT TCGGGGCCCGAGGCTCCACCGGCGAGGCGGTGCTCTGGGGCGAGCGCCTGGGCGCGGCCCTCGCCAACATGGCCGCTTAC CAGGGCTATGCCGCCGTGGCCTACCCGCAAGGCAGCCTTCTGTCCTGGACCACGGTGGAGAAGGGCGGAATCATCGTAGG CGACGACGCCCGGCGGTTCGGCGACGAGAGCCTGGGCTATTCGGGCTATGCCCGGATCGTGCTGTCGCGCGGCGGCGACG CCTATGTCGTGTTCGACCAGAAGATCTTCGACGTCGCGGCGGCCGAGGAGGAGTTCATGGAACTCTGGACCTATGGCGGG CTCAAGCGCGGCGAGACGCCCGCCGAGATCGCCCGCCCGTTCGGCCTCGACGCGGCGGCGCTCGGGGAAGAGATCGCGAT GCGCAACGCGGCCGCCGCCGGGACCGCGCCGGATCGCCACGGCCGGCGGGATTTCGGCCTCGGGCCGCTGGAGCCGCCCT TCTACATCGGCCGTGTCGTGCCGGGGCTCTTCCACACGCAGGGTGGGCTGAAGGTCGACGGGGACGCCCGGGTGCTGCGG CCCGATGGAACGCCGGTGCCGAACCTGTTCGCAGGCGGCGGCGCGGCGGCCGGGATCAGCGGCCGGTCCGGCGCGCTCGG CTACGCTTCCGGCAATGGCCTCCTGTCGGCCATCGCGCTCGGGCGCCTCGCCGCGCTCGCCGCGGCGCGCGAACTCGGAC GGACGCCGTGA
Upstream 100 bases:
>100_bases TTCCCCGGATGGCGTCCTGCCTCGGCGCGATCGTTCAGGGCGGGCGCGGTGCGGCGCCGTGGCGGGACTGCGTGGCCGAG ATGACGAGTGAGGTGGTGCG
Downstream 100 bases:
>100_bases CGATCGCCCGCAGCCTCGCCCGGCGCGTCCGTGCGCTCGCGCGGGACAAGCTGCCGCCGGCGGTCGATGCGGCGGCGCGC CTCCACCTGCTCGACGCGAT
Product: fumarate reductase/succinate dehydrogenase flavoprotein domain protein
Products: NA
Alternate protein names: Fe(3+)-induced flavocytochrome C3; Ifc3; Iron(III)-induced flavocytochrome C3 [H]
Number of amino acids: Translated: 456; Mature: 455
Protein sequence:
>456_residues MSEDDLDILVIGAGACGLAAAVAGHDAGASVAVIEKQERPGGNSSLSTGSVPAAGSRFQREAGIDDDPARMVRDLMAIAR ETDDRALVERLAGVSAETVEWLVDTVGARLALITAYKHIGHSVPRLHAPVSRRGQDLVDDLVAAAERRGIPIAVGNGATD LLVEDGAVRGAIVSVEGERTEIRAGKTILALNGFAANPDLVRRFCPEIAGAQYFGARGSTGEAVLWGERLGAALANMAAY QGYAAVAYPQGSLLSWTTVEKGGIIVGDDARRFGDESLGYSGYARIVLSRGGDAYVVFDQKIFDVAAAEEEFMELWTYGG LKRGETPAEIARPFGLDAAALGEEIAMRNAAAAGTAPDRHGRRDFGLGPLEPPFYIGRVVPGLFHTQGGLKVDGDARVLR PDGTPVPNLFAGGGAAAGISGRSGALGYASGNGLLSAIALGRLAALAAARELGRTP
Sequences:
>Translated_456_residues MSEDDLDILVIGAGACGLAAAVAGHDAGASVAVIEKQERPGGNSSLSTGSVPAAGSRFQREAGIDDDPARMVRDLMAIAR ETDDRALVERLAGVSAETVEWLVDTVGARLALITAYKHIGHSVPRLHAPVSRRGQDLVDDLVAAAERRGIPIAVGNGATD LLVEDGAVRGAIVSVEGERTEIRAGKTILALNGFAANPDLVRRFCPEIAGAQYFGARGSTGEAVLWGERLGAALANMAAY QGYAAVAYPQGSLLSWTTVEKGGIIVGDDARRFGDESLGYSGYARIVLSRGGDAYVVFDQKIFDVAAAEEEFMELWTYGG LKRGETPAEIARPFGLDAAALGEEIAMRNAAAAGTAPDRHGRRDFGLGPLEPPFYIGRVVPGLFHTQGGLKVDGDARVLR PDGTPVPNLFAGGGAAAGISGRSGALGYASGNGLLSAIALGRLAALAAARELGRTP >Mature_455_residues SEDDLDILVIGAGACGLAAAVAGHDAGASVAVIEKQERPGGNSSLSTGSVPAAGSRFQREAGIDDDPARMVRDLMAIARE TDDRALVERLAGVSAETVEWLVDTVGARLALITAYKHIGHSVPRLHAPVSRRGQDLVDDLVAAAERRGIPIAVGNGATDL LVEDGAVRGAIVSVEGERTEIRAGKTILALNGFAANPDLVRRFCPEIAGAQYFGARGSTGEAVLWGERLGAALANMAAYQ GYAAVAYPQGSLLSWTTVEKGGIIVGDDARRFGDESLGYSGYARIVLSRGGDAYVVFDQKIFDVAAAEEEFMELWTYGGL KRGETPAEIARPFGLDAAALGEEIAMRNAAAAGTAPDRHGRRDFGLGPLEPPFYIGRVVPGLFHTQGGLKVDGDARVLRP DGTPVPNLFAGGGAAAGISGRSGALGYASGNGLLSAIALGRLAALAAARELGRTP
Specific function: Catalyzes unidirectional fumarate reduction using artificial electron donors such as methyl viologen. The physiological reductant is unknown [H]
COG id: COG1053
COG function: function code C; Succinate dehydrogenase/fumarate reductase, flavoprotein subunit
Gene ontology:
Cell location: Periplasm [H]
Metaboloic importance: NA
Operon status: Not Known
Operon components: None
Similarity: Contains 1 cytochrome c domain [H]
Homologues:
Organism=Caenorhabditis elegans, GI71986328, Length=477, Percent_Identity=26.8343815513627, Blast_Score=138, Evalue=5e-33, Organism=Saccharomyces cerevisiae, GI6320788, Length=475, Percent_Identity=24.6315789473684, Blast_Score=105, Evalue=2e-23,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR003953 - InterPro: IPR013027 - InterPro: IPR010960 - InterPro: IPR011031 [H]
Pfam domain/function: PF00890 FAD_binding_2 [H]
EC number: =1.3.99.1 [H]
Molecular weight: Translated: 47167; Mature: 47035
Theoretical pI: Translated: 4.93; Mature: 4.93
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.4 %Cys (Translated Protein) 1.3 %Met (Translated Protein) 1.8 %Cys+Met (Translated Protein) 0.4 %Cys (Mature Protein) 1.1 %Met (Mature Protein) 1.5 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MSEDDLDILVIGAGACGLAAAVAGHDAGASVAVIEKQERPGGNSSLSTGSVPAAGSRFQR CCCCCEEEEEECCCHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCHHHH EAGIDDDPARMVRDLMAIARETDDRALVERLAGVSAETVEWLVDTVGARLALITAYKHIG HCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHC HSVPRLHAPVSRRGQDLVDDLVAAAERRGIPIAVGNGATDLLVEDGAVRGAIVSVEGERT CCCCHHCCCHHHCCHHHHHHHHHHHHHCCCCEEECCCCCEEEEECCCCCEEEEEECCCCE EIRAGKTILALNGFAANPDLVRRFCPEIAGAQYFGARGSTGEAVLWGERLGAALANMAAY EECCCCEEEEECCCCCCHHHHHHHHHHHCCCCEECCCCCCCCEEEEHHHHHHHHHHHHHH QGYAAVAYPQGSLLSWTTVEKGGIIVGDDARRFGDESLGYSGYARIVLSRGGDAYVVFDQ CCCEEEEECCCCEEEEEEECCCCEEECCCHHHCCCCCCCCCCEEEEEEECCCCEEEEECC KIFDVAAAEEEFMELWTYGGLKRGETPAEIARPFGLDAAALGEEIAMRNAAAAGTAPDRH HHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCCC GRRDFGLGPLEPPFYIGRVVPGLFHTQGGLKVDGDARVLRPDGTPVPNLFAGGGAAAGIS CCCCCCCCCCCCCHHHHHHHHHHHCCCCCEEECCCCEEECCCCCCCCCEECCCCCCCCCC GRSGALGYASGNGLLSAIALGRLAALAAARELGRTP CCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHCCCC >Mature Secondary Structure SEDDLDILVIGAGACGLAAAVAGHDAGASVAVIEKQERPGGNSSLSTGSVPAAGSRFQR CCCCEEEEEECCCHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCHHHH EAGIDDDPARMVRDLMAIARETDDRALVERLAGVSAETVEWLVDTVGARLALITAYKHIG HCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHC HSVPRLHAPVSRRGQDLVDDLVAAAERRGIPIAVGNGATDLLVEDGAVRGAIVSVEGERT CCCCHHCCCHHHCCHHHHHHHHHHHHHCCCCEEECCCCCEEEEECCCCCEEEEEECCCCE EIRAGKTILALNGFAANPDLVRRFCPEIAGAQYFGARGSTGEAVLWGERLGAALANMAAY EECCCCEEEEECCCCCCHHHHHHHHHHHCCCCEECCCCCCCCEEEEHHHHHHHHHHHHHH QGYAAVAYPQGSLLSWTTVEKGGIIVGDDARRFGDESLGYSGYARIVLSRGGDAYVVFDQ CCCEEEEECCCCEEEEEEECCCCEEECCCHHHCCCCCCCCCCEEEEEEECCCCEEEEECC KIFDVAAAEEEFMELWTYGGLKRGETPAEIARPFGLDAAALGEEIAMRNAAAAGTAPDRH HHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCCC GRRDFGLGPLEPPFYIGRVVPGLFHTQGGLKVDGDARVLRPDGTPVPNLFAGGGAAAGIS CCCCCCCCCCCCCHHHHHHHHHHHCCCCCEEECCCCEEECCCCCCCCCEECCCCCCCCCC GRSGALGYASGNGLLSAIALGRLAALAAARELGRTP CCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 10455032; 10581549 [H]