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The map label for this gene is etfA [H]

Identifier: 220914802

GI number: 220914802

Start: 163127

End: 164074

Strand: Reverse

Name: etfA [H]

Synonym: Mnod_7938

Alternate gene names: 220914802

Gene position: 164074-163127 (Counterclockwise)

Preceding gene: 220914803

Following gene: 220914796

Centisome position: 35.82

GC content: 71.41

Gene sequence:

>948_bases
ATGGCCACCCTGCTTCTCGTCGAGCACGCCCACGGCGCGCCCAAGGACGGTTCCCTGAAGGCGCTCACCGCCGCCCGGCA
GCTCGGCGCCCCGGTCCACGCCCTGGTGACCGGCGCCGGCAGCCGGCCGGCGGCCGAGGCCACCGCCCGGCTTGAGGGTG
TCGAAAAAGTGCTGCTGGCCGAGAACGCCGCCTTCGACCACCTGCTGGCCGAGCCGACCGCGGCGCTGCTTGCCGAGCTG
GCGGCGGGCTACGACGCGGTGATCGCGGCGGCGAGCACCGAGGGCAAGAACGTGCTGCCGCGCGTCGCCGCGCTGCTCGA
CGTGGCGCAGGTCTCGGACATCACCAAGGTGGTGGCGCCCGACACCTTCGAGCGGCCGATCTATGCCGGCAACGCGATCC
AGACCGTGCAGGTGAGCGAGCCGAAAAAGGTGATCACGGTGCGCACCGCCGCCTTCAAGGCGGCCGAGGCGGGCGGCGCG
CCAGCCCCGATCGAGGCGGCGGCAGCGGCAGTGGCGCCGGAGGTGAAGTCGGCGTTCAAGGGCGAGGAGATCGCCCAGTC
GGACCGGCCGGAGCTGGCCTCGGCCCGGATCGTGGTGTCGGGCGGGCGCTCGCTGGGCTCGGCGGAGAAGTTCAGGGAGC
TGATCGAGCCGCTGGCGGATGCGCTGGGGGCGGCGGTGGGGGCCTCGCGGGCGGCGGTGGATGCGGGCTACGCGCCGAAC
GACTGGCAGGTGGGCCAGACCGGCAAGGTGGTGGCGCCGGAGCTCTATGTGGCGGTGGGGATCTCGGGGGCGATCCAGCA
TCTGGCGGGGATGAAGGATTCCAAGGTGATCGTGGCGATCAACAAGGACGAGGAGGCGCCGATCTTTCAGGTGGCGGATT
ACGGCCTGGTCGGCGACCTGTTCCAGATCGTGCCTGAACTTATGGACGCGATCGAACACGGACGCTGA

Upstream 100 bases:

>100_bases
GCCGGGGTCAAGGTCGCCTCGGCGGCCGAACTCGTCAGCAAGCTGAAGGGCGAGGCCGGCGTCCTCTGACGCGCCTCCCG
ATCGAGAGGAAACACGGAAG

Downstream 100 bases:

>100_bases
ACGCAACCACGGATGCGGCGATTGCTGAAGCGAGACGCGATCCGCGGCCGGCAGCTTGGACGAGGTGCGCGGCGTCTTCT
CAGACGCTGCAGCCGCAGCA

Product: Electron transfer flavoprotein alpha subunit

Products: NA

Alternate protein names: Alpha-ETF; Electron transfer flavoprotein large subunit; ETFLS [H]

Number of amino acids: Translated: 315; Mature: 314

Protein sequence:

>315_residues
MATLLLVEHAHGAPKDGSLKALTAARQLGAPVHALVTGAGSRPAAEATARLEGVEKVLLAENAAFDHLLAEPTAALLAEL
AAGYDAVIAAASTEGKNVLPRVAALLDVAQVSDITKVVAPDTFERPIYAGNAIQTVQVSEPKKVITVRTAAFKAAEAGGA
PAPIEAAAAAVAPEVKSAFKGEEIAQSDRPELASARIVVSGGRSLGSAEKFRELIEPLADALGAAVGASRAAVDAGYAPN
DWQVGQTGKVVAPELYVAVGISGAIQHLAGMKDSKVIVAINKDEEAPIFQVADYGLVGDLFQIVPELMDAIEHGR

Sequences:

>Translated_315_residues
MATLLLVEHAHGAPKDGSLKALTAARQLGAPVHALVTGAGSRPAAEATARLEGVEKVLLAENAAFDHLLAEPTAALLAEL
AAGYDAVIAAASTEGKNVLPRVAALLDVAQVSDITKVVAPDTFERPIYAGNAIQTVQVSEPKKVITVRTAAFKAAEAGGA
PAPIEAAAAAVAPEVKSAFKGEEIAQSDRPELASARIVVSGGRSLGSAEKFRELIEPLADALGAAVGASRAAVDAGYAPN
DWQVGQTGKVVAPELYVAVGISGAIQHLAGMKDSKVIVAINKDEEAPIFQVADYGLVGDLFQIVPELMDAIEHGR
>Mature_314_residues
ATLLLVEHAHGAPKDGSLKALTAARQLGAPVHALVTGAGSRPAAEATARLEGVEKVLLAENAAFDHLLAEPTAALLAELA
AGYDAVIAAASTEGKNVLPRVAALLDVAQVSDITKVVAPDTFERPIYAGNAIQTVQVSEPKKVITVRTAAFKAAEAGGAP
APIEAAAAAVAPEVKSAFKGEEIAQSDRPELASARIVVSGGRSLGSAEKFRELIEPLADALGAAVGASRAAVDAGYAPND
WQVGQTGKVVAPELYVAVGISGAIQHLAGMKDSKVIVAINKDEEAPIFQVADYGLVGDLFQIVPELMDAIEHGR

Specific function: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase) [H]

COG id: COG2025

COG function: function code C; Electron transfer flavoprotein, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ETF alpha-subunit/fixB family [H]

Homologues:

Organism=Homo sapiens, GI4503607, Length=313, Percent_Identity=52.7156549520767, Blast_Score=306, Evalue=2e-83,
Organism=Homo sapiens, GI189181759, Length=277, Percent_Identity=54.8736462093863, Blast_Score=283, Evalue=1e-76,
Organism=Escherichia coli, GI1786226, Length=257, Percent_Identity=35.0194552529183, Blast_Score=125, Evalue=3e-30,
Organism=Escherichia coli, GI1787990, Length=295, Percent_Identity=31.5254237288136, Blast_Score=115, Evalue=4e-27,
Organism=Escherichia coli, GI87082157, Length=230, Percent_Identity=30.8695652173913, Blast_Score=80, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17506929, Length=312, Percent_Identity=52.2435897435897, Blast_Score=303, Evalue=7e-83,
Organism=Saccharomyces cerevisiae, GI6325261, Length=321, Percent_Identity=46.1059190031153, Blast_Score=266, Evalue=3e-72,
Organism=Drosophila melanogaster, GI17136898, Length=308, Percent_Identity=54.8701298701299, Blast_Score=313, Evalue=1e-85,
Organism=Drosophila melanogaster, GI24652801, Length=308, Percent_Identity=54.8701298701299, Blast_Score=313, Evalue=1e-85,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001308
- InterPro:   IPR014730
- InterPro:   IPR014731
- InterPro:   IPR018206
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01012 ETF; PF00766 ETF_alpha [H]

EC number: NA

Molecular weight: Translated: 32221; Mature: 32090

Theoretical pI: Translated: 4.77; Mature: 4.77

Prosite motif: PS00696 ETF_ALPHA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
0.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATLLLVEHAHGAPKDGSLKALTAARQLGAPVHALVTGAGSRPAAEATARLEGVEKVLLA
CCEEEEEECCCCCCCCCCHHHHHHHHHHCCCHHHEEECCCCCCHHHHHHHHHHHHHHHHH
ENAAFDHLLAEPTAALLAELAAGYDAVIAAASTEGKNVLPRVAALLDVAQVSDITKVVAP
CCCHHHHHHHCHHHHHHHHHHCCHHHEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCC
DTFERPIYAGNAIQTVQVSEPKKVITVRTAAFKAAEAGGAPAPIEAAAAAVAPEVKSAFK
CCCCCCEECCCCEEEEEECCCCEEEEEEHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHC
GEEIAQSDRPELASARIVVSGGRSLGSAEKFRELIEPLADALGAAVGASRAAVDAGYAPN
CHHHHHCCCCCHHHEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCC
DWQVGQTGKVVAPELYVAVGISGAIQHLAGMKDSKVIVAINKDEEAPIFQVADYGLVGDL
CCCCCCCCCEECCCEEEEECHHHHHHHHHCCCCCEEEEEECCCCCCCEEEECCCCHHHHH
FQIVPELMDAIEHGR
HHHHHHHHHHHHCCC
>Mature Secondary Structure 
ATLLLVEHAHGAPKDGSLKALTAARQLGAPVHALVTGAGSRPAAEATARLEGVEKVLLA
CEEEEEECCCCCCCCCCHHHHHHHHHHCCCHHHEEECCCCCCHHHHHHHHHHHHHHHHH
ENAAFDHLLAEPTAALLAELAAGYDAVIAAASTEGKNVLPRVAALLDVAQVSDITKVVAP
CCCHHHHHHHCHHHHHHHHHHCCHHHEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCC
DTFERPIYAGNAIQTVQVSEPKKVITVRTAAFKAAEAGGAPAPIEAAAAAVAPEVKSAFK
CCCCCCEECCCCEEEEEECCCCEEEEEEHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHC
GEEIAQSDRPELASARIVVSGGRSLGSAEKFRELIEPLADALGAAVGASRAAVDAGYAPN
CHHHHHCCCCCHHHEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCC
DWQVGQTGKVVAPELYVAVGISGAIQHLAGMKDSKVIVAINKDEEAPIFQVADYGLVGDL
CCCCCCCCCEECCCEEEEECHHHHHHHHHCCCCCEEEEEECCCCCCCEEEECCCCHHHHH
FQIVPELMDAIEHGR
HHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8599534; 12597275 [H]