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The map label for this gene is feaR [H]

Identifier: 220914782

GI number: 220914782

Start: 142838

End: 143830

Strand: Reverse

Name: feaR [H]

Synonym: Mnod_7915

Alternate gene names: 220914782

Gene position: 143830-142838 (Counterclockwise)

Preceding gene: 220914790

Following gene: 220914781

Centisome position: 31.4

GC content: 64.25

Gene sequence:

>993_bases
ATGCCGTTGGAGGACATTTCTATTGACGGCCGCGATATGTCTCTGAGGGAGAGAAAGTTGTGCTGGCAGGCACTTGTCGG
CGAGCATTTGGCCGATGTCGAACTCGACGCCTCCCCCGATATTCCCGCAGGTGAGGCATTCGCCGGGACGCTTCGGATCC
GAAGCTTCGAGCGCGGCACGCTCGCAGACATCGCCAGCGGGGGACAGGTGCTCACCCGCACGGCCGATCGCATCCGTCGG
GCGAAGTCCGACGCGGTCCTGTTCAATATCATCCTCTCGGGGCATTGCCGCCTCGAGCAGGACGGGCGCCAGGCTGTACC
AACGGCGGGCAGCCTCTTCCTCTATGAGAGCGCGCGTCCCTACCACATCGAGACCTCGCCCGATTTCCGCACCATTGTCG
TCATGATCGACCGCGGACGGCTCGAGAGGAGCCTCGGAAATCTGCGCTTCTATACCGGACGAGCGATGTGCTCGGTCGAC
ACGGTGGCGCGCATTGCAGGCTCGTTCTGGCAGACTCTCTCGAGTCAACTCGACGGCGTTCCGGATGCTGCGGCCAACAC
GCTGATCGAAGCCGGCATCGACGTCGTCATCCCCGCTCTGAGGTCGATGGCGGGTGACCGGGCAGAGGGATCGGAAGCCT
GCGAACTGACGGTCATGCGCGCCACGGCGTTCATCGCCAGCGCCTTCCACAGGGAGAGCCTGACCGTCGACGACATTGCC
GCGGCCGCCGGCGTTTCGACGCGCCGTCTCCAGGAATGCTTCAAGGAAAAGGGGCTCACGCCGATGGAGCAGTTGCGCAA
GCACCGCCTGAAGCACGCCCACGATCGCCTGAACGACGGCCATTGCCAGAACCTGTCGGTCCTCAGCATCATGAGCCAGT
CGGGCTTCAGCGATCCGGCGCATTTCAGCCGGGCGTTCCGCAAGGAATACGGCATATCCCCATCGGCTGCTCGATCCGCC
TCGCAGCGCCGCCCCGCAGTTCGGGTCGCCTGA

Upstream 100 bases:

>100_bases
CCACGGCCCGGCTTGGATTGAACCGTATAGCACGTTAGAAACGGGATAACCGGCCGACCAAGACGCTGGTGCATACAGTA
TACAAGGGAGATGCGACCGA

Downstream 100 bases:

>100_bases
CAAGAGGGCGATCTCCCGCCGGTATTGTCACGAGAAACGATGGCAGACGAGCTCTGGTCGAGGTAGGGAGGGGGACTGTC
GGGAATTCCGTGTGCAGGCG

Product: transcriptional regulator, AraC family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 330; Mature: 329

Protein sequence:

>330_residues
MPLEDISIDGRDMSLRERKLCWQALVGEHLADVELDASPDIPAGEAFAGTLRIRSFERGTLADIASGGQVLTRTADRIRR
AKSDAVLFNIILSGHCRLEQDGRQAVPTAGSLFLYESARPYHIETSPDFRTIVVMIDRGRLERSLGNLRFYTGRAMCSVD
TVARIAGSFWQTLSSQLDGVPDAAANTLIEAGIDVVIPALRSMAGDRAEGSEACELTVMRATAFIASAFHRESLTVDDIA
AAAGVSTRRLQECFKEKGLTPMEQLRKHRLKHAHDRLNDGHCQNLSVLSIMSQSGFSDPAHFSRAFRKEYGISPSAARSA
SQRRPAVRVA

Sequences:

>Translated_330_residues
MPLEDISIDGRDMSLRERKLCWQALVGEHLADVELDASPDIPAGEAFAGTLRIRSFERGTLADIASGGQVLTRTADRIRR
AKSDAVLFNIILSGHCRLEQDGRQAVPTAGSLFLYESARPYHIETSPDFRTIVVMIDRGRLERSLGNLRFYTGRAMCSVD
TVARIAGSFWQTLSSQLDGVPDAAANTLIEAGIDVVIPALRSMAGDRAEGSEACELTVMRATAFIASAFHRESLTVDDIA
AAAGVSTRRLQECFKEKGLTPMEQLRKHRLKHAHDRLNDGHCQNLSVLSIMSQSGFSDPAHFSRAFRKEYGISPSAARSA
SQRRPAVRVA
>Mature_329_residues
PLEDISIDGRDMSLRERKLCWQALVGEHLADVELDASPDIPAGEAFAGTLRIRSFERGTLADIASGGQVLTRTADRIRRA
KSDAVLFNIILSGHCRLEQDGRQAVPTAGSLFLYESARPYHIETSPDFRTIVVMIDRGRLERSLGNLRFYTGRAMCSVDT
VARIAGSFWQTLSSQLDGVPDAAANTLIEAGIDVVIPALRSMAGDRAEGSEACELTVMRATAFIASAFHRESLTVDDIAA
AAGVSTRRLQECFKEKGLTPMEQLRKHRLKHAHDRLNDGHCQNLSVLSIMSQSGFSDPAHFSRAFRKEYGISPSAARSAS
QRRPAVRVA

Specific function: Positive regulator of tynA/maoA and feaB/padA, the genes for 2-phenylethylamine catabolism [H]

COG id: COG2207

COG function: function code K; AraC-type DNA-binding domain-containing proteins

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH araC/xylS-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787649, Length=278, Percent_Identity=25.1798561151079, Blast_Score=76, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR012287
- InterPro:   IPR020449
- InterPro:   IPR018060 [H]

Pfam domain/function: PF00165 HTH_AraC [H]

EC number: NA

Molecular weight: Translated: 36139; Mature: 36008

Theoretical pI: Translated: 7.88; Mature: 7.88

Prosite motif: PS01124 HTH_ARAC_FAMILY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLEDISIDGRDMSLRERKLCWQALVGEHLADVELDASPDIPAGEAFAGTLRIRSFERGT
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHEEEEEECCCCC
LADIASGGQVLTRTADRIRRAKSDAVLFNIILSGHCRLEQDGRQAVPTAGSLFLYESARP
HHHHHCCCHHHHHHHHHHHHHCCCHHEEEEECCCCCEECCCCCCCCCCCCCEEEEECCCC
YHIETSPDFRTIVVMIDRGRLERSLGNLRFYTGRAMCSVDTVARIAGSFWQTLSSQLDGV
EEEECCCCCEEEEEEECCCHHHHHHCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCC
PDAAANTLIEAGIDVVIPALRSMAGDRAEGSEACELTVMRATAFIASAFHRESLTVDDIA
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHH
AAAGVSTRRLQECFKEKGLTPMEQLRKHRLKHAHDRLNDGHCQNLSVLSIMSQSGFSDPA
HHCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCCHH
HFSRAFRKEYGISPSAARSASQRRPAVRVA
HHHHHHHHHHCCCHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
PLEDISIDGRDMSLRERKLCWQALVGEHLADVELDASPDIPAGEAFAGTLRIRSFERGT
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHEEEEEECCCCC
LADIASGGQVLTRTADRIRRAKSDAVLFNIILSGHCRLEQDGRQAVPTAGSLFLYESARP
HHHHHCCCHHHHHHHHHHHHHCCCHHEEEEECCCCCEECCCCCCCCCCCCCEEEEECCCC
YHIETSPDFRTIVVMIDRGRLERSLGNLRFYTGRAMCSVDTVARIAGSFWQTLSSQLDGV
EEEECCCCCEEEEEEECCCHHHHHHCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCC
PDAAANTLIEAGIDVVIPALRSMAGDRAEGSEACELTVMRATAFIASAFHRESLTVDDIA
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHH
AAAGVSTRRLQECFKEKGLTPMEQLRKHRLKHAHDRLNDGHCQNLSVLSIMSQSGFSDPA
HHCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCCHH
HFSRAFRKEYGISPSAARSASQRRPAVRVA
HHHHHHHHHHCCCHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8631685; 9043126; 9278503; 9109378 [H]