Click here to switch to the map view.

The map label for this gene is dgoD [H]

Identifier: 220914741

GI number: 220914741

Start: 87313

End: 88503

Strand: Reverse

Name: dgoD [H]

Synonym: Mnod_7855

Alternate gene names: 220914741

Gene position: 88503-87313 (Counterclockwise)

Preceding gene: 220914742

Following gene: 220914740

Centisome position: 19.32

GC content: 59.87

Gene sequence:

>1191_bases
ATGATGAAGATCATCAAGATCGAAACGCTTGAGATCGAACTCTCGGGCCAGTGCGGCATCGCCTCCTGGCGGCCGGTCTT
CGTGCGTATCCATACGGACGCAGGAATCACCGGCATGGGCGAGGTTGGGCTTGCCTATGGCACTGGCACCCCGGCCGCTG
CCCCGATGATCCGTATCATCGGCGAGCGCCTCGTCCTCGGCAGGGACCCGAACGACACCGAGACTATCTGGGAGCACATG
CTGCGCCGTTCGTTCTGGGCTGAAGGTGGAGGGCCGGTCGTTTTCGGGGCGATGAGCGCAATCGACGCAGCGCTCTGGGA
TATTAAGGGGAAGGCAGCAGGTCTCCCAGTCCACCGCCTCCTCGGAGCGGAGACGCCGCTACCGCTGCGCTGCTATGCCA
GTCAGATGCAGTTCGGGTGGGAAGACATCAGCGTCCTGAAAAACAGTCCGTCTGAATATCGTGATACCGCGCAAACTGCG
CGAGCACAGGGCTACGACTGCGTCAAAGTCAGCCCCATCTACGTCGCTCCAGATGGTCAACGCGCACGAAATCGCGGTGT
CTTCACCCCCGAATTTCGCAAGTTGGCTCGCGCGCGAATGGAGGCTGTCCGGGATGGTGTCGGGCCCGATGCCGATATCA
TCCTCGAATTGAATTCGCTCACGTCGACAGCCGGCGCTCTTCAACTGGCCGAACTGTTCTCCGACCTCGGCATCCTTTTC
ATGGAAGAGCCAACTCACTCCAATAGCCCCGAGGCGTTCGTAAAAGTCTCATCGCGCTCGCCGATTCCGCTGGCGACTGG
GGAACGGCTTTACACGCGCTGGGGCTTCCTGCCCTACCTCCAAGCCGGCTCCATCGATATGATCCAGCCCGATATGGGAT
TGGTCGGTGGCGTTTCAGAAGGCATCAAGATCGCGCATCTGGCGCACGCATTCGACGTCGGGTTTCAAGCGCATATCTGC
GGCTCTCCTCTAGCTACCGCAATCGCGCTTCAGGTCGAGGCTGCGATTCCGAACCTCGAAATCCATGAGCATCACACCTT
CGCCTTGAAATCCTGCAACCGCGATCTGTTCGAGGAGGACCTTCAGCCCGTCAATGGGCACCTGGCTGTCCCTACAGCAC
CGGGCTTCGGCATGACCTTGAGGAAGGACGCCGAAAAGCGCATGGAAATCTCCGAAGTCAGCTTAGCGTGA

Upstream 100 bases:

>100_bases
AGCCATCCGCCCAGATCTCAACCTTAGTCCCAACGCATCAAACCGTTACTCGGACGGGCTCCTAGATCGGCTCGGGCAGG
GCGCCCGCTTCGGAGACAGC

Downstream 100 bases:

>100_bases
GAGCCTCCTCCCACAACCTGCCTGACGGATCTGCGCGATGCAGTCCGCGAGCATCGGCTCGGCCGCCGAGACGCATTGCG
GCCGTGGGCATTGGGTTGGA

Product: Mandelate racemase/muconate lactonizing protein

Products: NA

Alternate protein names: GalD [H]

Number of amino acids: Translated: 396; Mature: 396

Protein sequence:

>396_residues
MMKIIKIETLEIELSGQCGIASWRPVFVRIHTDAGITGMGEVGLAYGTGTPAAAPMIRIIGERLVLGRDPNDTETIWEHM
LRRSFWAEGGGPVVFGAMSAIDAALWDIKGKAAGLPVHRLLGAETPLPLRCYASQMQFGWEDISVLKNSPSEYRDTAQTA
RAQGYDCVKVSPIYVAPDGQRARNRGVFTPEFRKLARARMEAVRDGVGPDADIILELNSLTSTAGALQLAELFSDLGILF
MEEPTHSNSPEAFVKVSSRSPIPLATGERLYTRWGFLPYLQAGSIDMIQPDMGLVGGVSEGIKIAHLAHAFDVGFQAHIC
GSPLATAIALQVEAAIPNLEIHEHHTFALKSCNRDLFEEDLQPVNGHLAVPTAPGFGMTLRKDAEKRMEISEVSLA

Sequences:

>Translated_396_residues
MMKIIKIETLEIELSGQCGIASWRPVFVRIHTDAGITGMGEVGLAYGTGTPAAAPMIRIIGERLVLGRDPNDTETIWEHM
LRRSFWAEGGGPVVFGAMSAIDAALWDIKGKAAGLPVHRLLGAETPLPLRCYASQMQFGWEDISVLKNSPSEYRDTAQTA
RAQGYDCVKVSPIYVAPDGQRARNRGVFTPEFRKLARARMEAVRDGVGPDADIILELNSLTSTAGALQLAELFSDLGILF
MEEPTHSNSPEAFVKVSSRSPIPLATGERLYTRWGFLPYLQAGSIDMIQPDMGLVGGVSEGIKIAHLAHAFDVGFQAHIC
GSPLATAIALQVEAAIPNLEIHEHHTFALKSCNRDLFEEDLQPVNGHLAVPTAPGFGMTLRKDAEKRMEISEVSLA
>Mature_396_residues
MMKIIKIETLEIELSGQCGIASWRPVFVRIHTDAGITGMGEVGLAYGTGTPAAAPMIRIIGERLVLGRDPNDTETIWEHM
LRRSFWAEGGGPVVFGAMSAIDAALWDIKGKAAGLPVHRLLGAETPLPLRCYASQMQFGWEDISVLKNSPSEYRDTAQTA
RAQGYDCVKVSPIYVAPDGQRARNRGVFTPEFRKLARARMEAVRDGVGPDADIILELNSLTSTAGALQLAELFSDLGILF
MEEPTHSNSPEAFVKVSSRSPIPLATGERLYTRWGFLPYLQAGSIDMIQPDMGLVGGVSEGIKIAHLAHAFDVGFQAHIC
GSPLATAIALQVEAAIPNLEIHEHHTFALKSCNRDLFEEDLQPVNGHLAVPTAPGFGMTLRKDAEKRMEISEVSLA

Specific function: Catalyzes the dehydration of D-galactonate to 2-keto-3- deoxy-D-galactonate [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mandelate racemase/muconate lactonizing enzyme family. GalD subfamily [H]

Homologues:

Organism=Escherichia coli, GI48994953, Length=398, Percent_Identity=29.8994974874372, Blast_Score=153, Evalue=1e-38,
Organism=Escherichia coli, GI1787864, Length=396, Percent_Identity=25.2525252525253, Blast_Score=119, Evalue=5e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018110
- InterPro:   IPR013342
- InterPro:   IPR013341
- InterPro:   IPR001354 [H]

Pfam domain/function: PF01188 MR_MLE; PF02746 MR_MLE_N [H]

EC number: =4.2.1.6 [H]

Molecular weight: Translated: 42984; Mature: 42984

Theoretical pI: Translated: 5.60; Mature: 5.60

Prosite motif: PS00908 MR_MLE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMKIIKIETLEIELSGQCGIASWRPVFVRIHTDAGITGMGEVGLAYGTGTPAAAPMIRII
CEEEEEEEEEEEEECCCCCCCCCCEEEEEEECCCCCCCCCCCCEEECCCCCHHHHHHHHH
GERLVLGRDPNDTETIWEHMLRRSFWAEGGGPVVFGAMSAIDAALWDIKGKAAGLPVHRL
HHHHEECCCCCCHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHCCCCCCCCCHHHH
LGAETPLPLRCYASQMQFGWEDISVLKNSPSEYRDTAQTARAQGYDCVKVSPIYVAPDGQ
HCCCCCCCHHHHHHHHHCCHHHHHHHHCCCHHHHHHHHHHHHCCCCEEEEEEEEECCCCC
RARNRGVFTPEFRKLARARMEAVRDGVGPDADIILELNSLTSTAGALQLAELFSDLGILF
HHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHHHHCCCEEE
MEEPTHSNSPEAFVKVSSRSPIPLATGERLYTRWGFLPYLQAGSIDMIQPDMGLVGGVSE
EECCCCCCCCCEEEEECCCCCCCCCCCCHHHHHHCCCCEECCCCCEEECCCCCCCCCCCC
GIKIAHLAHAFDVGFQAHICGSPLATAIALQVEAAIPNLEIHEHHTFALKSCNRDLFEED
CEEHHHHHHHHHCCCEEEECCCHHHHHEEEEEEECCCCCEEECCCCHHHHHCCHHHHHHH
LQPVNGHLAVPTAPGFGMTLRKDAEKRMEISEVSLA
CCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MMKIIKIETLEIELSGQCGIASWRPVFVRIHTDAGITGMGEVGLAYGTGTPAAAPMIRII
CEEEEEEEEEEEEECCCCCCCCCCEEEEEEECCCCCCCCCCCCEEECCCCCHHHHHHHHH
GERLVLGRDPNDTETIWEHMLRRSFWAEGGGPVVFGAMSAIDAALWDIKGKAAGLPVHRL
HHHHEECCCCCCHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHCCCCCCCCCHHHH
LGAETPLPLRCYASQMQFGWEDISVLKNSPSEYRDTAQTARAQGYDCVKVSPIYVAPDGQ
HCCCCCCCHHHHHHHHHCCHHHHHHHHCCCHHHHHHHHHHHHCCCCEEEEEEEEECCCCC
RARNRGVFTPEFRKLARARMEAVRDGVGPDADIILELNSLTSTAGALQLAELFSDLGILF
HHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHHHHCCCEEE
MEEPTHSNSPEAFVKVSSRSPIPLATGERLYTRWGFLPYLQAGSIDMIQPDMGLVGGVSE
EECCCCCCCCCEEEEECCCCCCCCCCCCHHHHHHCCCCEECCCCCEEECCCCCCCCCCCC
GIKIAHLAHAFDVGFQAHICGSPLATAIALQVEAAIPNLEIHEHHTFALKSCNRDLFEED
CEEHHHHHHHHHCCCEEEECCCHHHHHEEEEEEECCCCCEEECCCCHHHHHCCHHHHHHH
LQPVNGHLAVPTAPGFGMTLRKDAEKRMEISEVSLA
CCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12024217 [H]