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The map label for this gene is dmsA [H]

Identifier: 220914739

GI number: 220914739

Start: 83329

End: 85683

Strand: Reverse

Name: dmsA [H]

Synonym: Mnod_7853

Alternate gene names: 220914739

Gene position: 85683-83329 (Counterclockwise)

Preceding gene: 220914740

Following gene: 220914738

Centisome position: 18.71

GC content: 59.75

Gene sequence:

>2355_bases
ATGCGTGACTCGCGGTTCGGCAATCCCGAAAGGGAGTCCGAGGTGCCTTTCAAGCCTCATTCCTCGCACTGGGGTGTCTT
CTCGGCGCGTATGATCGACGGCGAGCTGGAGGTGCGCCCGTACGAGGGTGATCCCGACCCGAATCAGATCATCGAGAACT
TTCCGGGAGCGCTCCGTCATCGTGCAAGGATCGCGCAACCGATGGTGCGCCGAGGCTGGCTCGAAAGAGGGCCAGGTCCC
GACGAGAAGCGCGGCCAAGACGAGTTTGTCCCGATGGCTTGGCAGGAGGTGCTCGACCTTCTGGGCCGCGAACTCGTCAG
GGTACGGGATGGCTTCGGGCCTGAGGCCATTTTTGGGGGGTCGTACGGGTGGTCGAGCGCTGGCCGATTTCACCACGCCC
AAAGCCAGATCCACCGTTTTCTCAACATTGCTTGTGGCGGCTACGTCAGATCCGTCACCAGCTACTCCTCTGGTTCGTCC
CAGGTGCTTATCCCCCACATTCTCGGCAACCACGAAGAATTGGCCAAACATAATGTAACTTGGGAACAGGTCGAGAAGGA
TAGTGAGATAGTAATCGCTTTCGGAGGGATGGCGTTAAAGAATAGCATGGTCGCAGGTGGCGGTATCAGCAAGCACGTTG
AGCGCGGCGTTATGCAGCGTGCGGCGGCTCGCGGCTGCGAATTCATTTTGGTCAGTCCACTAGCATCAGATCTTCCAGAG
GAGGCGCGGCCGGAGTGGGTTTCGCTGATTCCCGCGAGCGACACGGCACTAATGATGGCCATGGTGCATACGTTGGTCGT
GGAAGGGCGTCACGATCGAGCTTTCTTGGAGCGCTACACGGTCGGTTGGCCAACTTTCGAGCGATATCTCCTTGGTGAAG
CTGATGGCATTCCCAAGGATGCGCACTGGGCCGCACCTTTAACCGGTGTCCCGGCAGATGCGATTATGGCTCTAGCCCGC
CGATTGCACGGCAAACGGGCCCTGGTCGTCGTTTCGCACTCGCTGCAACGTGCACGATATGGCGAGCAGCCGGTATGGAT
GGGTATGGTCCTGGCTGCAGCACTTGGTCAGATTGGGTTGAGCGGAGGCGGGTATGCCTACCCGCTCGGCGCCATTGCTT
ACTACGGACGCCGCAAAAATGCGGTCAAGCTGCCCACCTTATCCCAGGGATCGAACAGCGTCCGAGAGTTCATACCGGTG
GCTCGTATCGCTGATATGCTGCTGGGCCCTGGTGAGGCCTATCGCTTCAATGGAAAAACTCTGACCTATCCGGAAATTAA
GCTGATTTACTGGGCGGGAGGGAATCCGTTTCACCATCACCAAGACTTGAACCGGTTGAAGAAAGCTTTCGCCGCGGTCG
ACACACTCGTTGTGCATGAACTCGCTTGGACCGCAACGGCGCGTCACGCCGACATCGTCCTGCCCTGTACGATGACGCTT
GAGCGTGACGACATTGGTGGTAGTTCCAACGACCCCTTGCTAGTGCCCATGCGGCAGATCGCGCCGCCTTATGGCGAAGC
TCGTGACGACTTCGCCATCTTCGCCGATTTGGCGGAGCGGCTCGGTGCGCGCGACGCTTTCACTGAAGGCCGCACTGTCC
GTCAATGGCTCGAACACCTGTACGAGCCGACGCGGCTGGGTTTGGTTCAGCTGAACCTGCCCGCGCCGAGCTTCGAGGAT
TTCTGGGAGAGTAGCGGTATCCTTGTTCCGCAAGGTCCGGACGATGGCGGAAACCTTCGCGCCTTCCGTGAAGATCCTCT
GGCCTCTCCTTTGGAAACTCCGAGCGGCAAGCTGGAGATCTTCTCGGAGACAATCGCGAGCTTCGGTGAGGCGGACTGTC
CAGGCCACCCGGCTTGGCTCGGATCAGGTTACCTTCCGACCGAGTCGGCTCCGCTGGTGCTGGTCTCAAACCAACCCCGC
ACTCGCTTGCATAGTCAGCTCGACTTCGGCGGGCACAGCGGCAGCGGCAAGCATCGTGGGCGTGAAATCGCAAGTATGCA
CCCGAAGGACGCCGCCGAGCGCGGAATTGCCGATGGCGACATCGTGCGCCTGTTCAATGAAAGGGGTGCTTGCCTCGCTG
CGATTGCCTTGACGGAGGACATCCGTCCGGGAGTGATTCAGTTACCTACAGGTGCCTGGTACGACCCGGCAGACCCAACC
GAGGAAAAAACTCTGTGTGTGCACGGTAATCCCAACGTTTTGACCGAAGACGTGGGCACCTCGGCACTGGCTCAGGGTTG
CACAGGGCAGCTTACGACGGTCGAAGTAGAGCGCTTCGATGGCAACTTGCCGCCCATCCGGGCGTACGATCCACCTTTGT
CACTCCCCGCGCCCGCTTCCCACCTTGATGGCTGA

Upstream 100 bases:

>100_bases
ACTTGAGGCGGCCTTTGCTGCGGTTTTCCGCCGCAAGGCCCATCGTCGCCGGTTCGCGGCGTGAGCGCGATCATCGAGCA
TACTTCGGAGGACATTTCCC

Downstream 100 bases:

>100_bases
CCCGCATTGCGTCGGGGTGGGGCTTGGAAAGCCGCTCCACCTCGGCGGGTGGCACGAGCCTGTATTCGCGCCGGGGTCCA
GTCTCGTCGACCGTGCCGTC

Product: molybdopterin oxidoreductase

Products: Biotin [C]

Alternate protein names: DMSO reductase; DMSOR [H]

Number of amino acids: Translated: 784; Mature: 784

Protein sequence:

>784_residues
MRDSRFGNPERESEVPFKPHSSHWGVFSARMIDGELEVRPYEGDPDPNQIIENFPGALRHRARIAQPMVRRGWLERGPGP
DEKRGQDEFVPMAWQEVLDLLGRELVRVRDGFGPEAIFGGSYGWSSAGRFHHAQSQIHRFLNIACGGYVRSVTSYSSGSS
QVLIPHILGNHEELAKHNVTWEQVEKDSEIVIAFGGMALKNSMVAGGGISKHVERGVMQRAAARGCEFILVSPLASDLPE
EARPEWVSLIPASDTALMMAMVHTLVVEGRHDRAFLERYTVGWPTFERYLLGEADGIPKDAHWAAPLTGVPADAIMALAR
RLHGKRALVVVSHSLQRARYGEQPVWMGMVLAAALGQIGLSGGGYAYPLGAIAYYGRRKNAVKLPTLSQGSNSVREFIPV
ARIADMLLGPGEAYRFNGKTLTYPEIKLIYWAGGNPFHHHQDLNRLKKAFAAVDTLVVHELAWTATARHADIVLPCTMTL
ERDDIGGSSNDPLLVPMRQIAPPYGEARDDFAIFADLAERLGARDAFTEGRTVRQWLEHLYEPTRLGLVQLNLPAPSFED
FWESSGILVPQGPDDGGNLRAFREDPLASPLETPSGKLEIFSETIASFGEADCPGHPAWLGSGYLPTESAPLVLVSNQPR
TRLHSQLDFGGHSGSGKHRGREIASMHPKDAAERGIADGDIVRLFNERGACLAAIALTEDIRPGVIQLPTGAWYDPADPT
EEKTLCVHGNPNVLTEDVGTSALAQGCTGQLTTVEVERFDGNLPPIRAYDPPLSLPAPASHLDG

Sequences:

>Translated_784_residues
MRDSRFGNPERESEVPFKPHSSHWGVFSARMIDGELEVRPYEGDPDPNQIIENFPGALRHRARIAQPMVRRGWLERGPGP
DEKRGQDEFVPMAWQEVLDLLGRELVRVRDGFGPEAIFGGSYGWSSAGRFHHAQSQIHRFLNIACGGYVRSVTSYSSGSS
QVLIPHILGNHEELAKHNVTWEQVEKDSEIVIAFGGMALKNSMVAGGGISKHVERGVMQRAAARGCEFILVSPLASDLPE
EARPEWVSLIPASDTALMMAMVHTLVVEGRHDRAFLERYTVGWPTFERYLLGEADGIPKDAHWAAPLTGVPADAIMALAR
RLHGKRALVVVSHSLQRARYGEQPVWMGMVLAAALGQIGLSGGGYAYPLGAIAYYGRRKNAVKLPTLSQGSNSVREFIPV
ARIADMLLGPGEAYRFNGKTLTYPEIKLIYWAGGNPFHHHQDLNRLKKAFAAVDTLVVHELAWTATARHADIVLPCTMTL
ERDDIGGSSNDPLLVPMRQIAPPYGEARDDFAIFADLAERLGARDAFTEGRTVRQWLEHLYEPTRLGLVQLNLPAPSFED
FWESSGILVPQGPDDGGNLRAFREDPLASPLETPSGKLEIFSETIASFGEADCPGHPAWLGSGYLPTESAPLVLVSNQPR
TRLHSQLDFGGHSGSGKHRGREIASMHPKDAAERGIADGDIVRLFNERGACLAAIALTEDIRPGVIQLPTGAWYDPADPT
EEKTLCVHGNPNVLTEDVGTSALAQGCTGQLTTVEVERFDGNLPPIRAYDPPLSLPAPASHLDG
>Mature_784_residues
MRDSRFGNPERESEVPFKPHSSHWGVFSARMIDGELEVRPYEGDPDPNQIIENFPGALRHRARIAQPMVRRGWLERGPGP
DEKRGQDEFVPMAWQEVLDLLGRELVRVRDGFGPEAIFGGSYGWSSAGRFHHAQSQIHRFLNIACGGYVRSVTSYSSGSS
QVLIPHILGNHEELAKHNVTWEQVEKDSEIVIAFGGMALKNSMVAGGGISKHVERGVMQRAAARGCEFILVSPLASDLPE
EARPEWVSLIPASDTALMMAMVHTLVVEGRHDRAFLERYTVGWPTFERYLLGEADGIPKDAHWAAPLTGVPADAIMALAR
RLHGKRALVVVSHSLQRARYGEQPVWMGMVLAAALGQIGLSGGGYAYPLGAIAYYGRRKNAVKLPTLSQGSNSVREFIPV
ARIADMLLGPGEAYRFNGKTLTYPEIKLIYWAGGNPFHHHQDLNRLKKAFAAVDTLVVHELAWTATARHADIVLPCTMTL
ERDDIGGSSNDPLLVPMRQIAPPYGEARDDFAIFADLAERLGARDAFTEGRTVRQWLEHLYEPTRLGLVQLNLPAPSFED
FWESSGILVPQGPDDGGNLRAFREDPLASPLETPSGKLEIFSETIASFGEADCPGHPAWLGSGYLPTESAPLVLVSNQPR
TRLHSQLDFGGHSGSGKHRGREIASMHPKDAAERGIADGDIVRLFNERGACLAAIALTEDIRPGVIQLPTGAWYDPADPT
EEKTLCVHGNPNVLTEDVGTSALAQGCTGQLTTVEVERFDGNLPPIRAYDPPLSLPAPASHLDG

Specific function: Terminal reductase during anaerobic growth on various sulfoxide and N-oxide compounds [H]

COG id: COG0243

COG function: function code C; Anaerobic dehydrogenases, typically selenocysteine-containing

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI87081994, Length=776, Percent_Identity=37.6288659793814, Blast_Score=527, Evalue=1e-150,
Organism=Escherichia coli, GI145693196, Length=729, Percent_Identity=40.6035665294925, Blast_Score=515, Evalue=1e-147,
Organism=Escherichia coli, GI1787231, Length=793, Percent_Identity=36.3177805800757, Blast_Score=485, Evalue=1e-138,
Organism=Escherichia coli, GI87081797, Length=780, Percent_Identity=29.4871794871795, Blast_Score=258, Evalue=1e-69,
Organism=Escherichia coli, GI1787870, Length=747, Percent_Identity=29.1834002677376, Blast_Score=232, Evalue=6e-62,
Organism=Escherichia coli, GI171474008, Length=746, Percent_Identity=27.2117962466488, Blast_Score=226, Evalue=5e-60,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009010
- InterPro:   IPR006658
- InterPro:   IPR006657
- InterPro:   IPR006656
- InterPro:   IPR006655
- InterPro:   IPR006311 [H]

Pfam domain/function: PF00384 Molybdopterin; PF01568 Molydop_binding [H]

EC number: 1.7.2.3 [C]

Molecular weight: Translated: 85756; Mature: 85756

Theoretical pI: Translated: 6.09; Mature: 6.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRDSRFGNPERESEVPFKPHSSHWGVFSARMIDGELEVRPYEGDPDPNQIIENFPGALRH
CCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCEEEEECCCCCCCHHHHHHHCCHHHHH
RARIAQPMVRRGWLERGPGPDEKRGQDEFVPMAWQEVLDLLGRELVRVRDGFGPEAIFGG
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEECC
SYGWSSAGRFHHAQSQIHRFLNIACGGYVRSVTSYSSGSSQVLIPHILGNHEELAKHNVT
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEHHHHCCHHHHHHCCCC
WEQVEKDSEIVIAFGGMALKNSMVAGGGISKHVERGVMQRAAARGCEFILVSPLASDLPE
HHHHCCCCCEEEEECCHHHHCCEECCCCHHHHHHHHHHHHHHHCCCCEEEECCHHHCCCH
EARPEWVSLIPASDTALMMAMVHTLVVEGRHDRAFLERYTVGWPTFERYLLGEADGIPKD
HHCCCEEEEECCCHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCHHHHHHHCCCCCCCCC
AHWAAPLTGVPADAIMALARRLHGKRALVVVSHSLQRARYGEQPVWMGMVLAAALGQIGL
CCCCCCCCCCCHHHHHHHHHHHCCCEEEEEEEHHHHHHHCCCCCHHHHHHHHHHHHHHCC
SGGGYAYPLGAIAYYGRRKNAVKLPTLSQGSNSVREFIPVARIADMLLGPGEAYRFNGKT
CCCCCCCHHHHHHHHCCCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEECCCE
LTYPEIKLIYWAGGNPFHHHQDLNRLKKAFAAVDTLVVHELAWTATARHADIVLPCTMTL
EECCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEE
ERDDIGGSSNDPLLVPMRQIAPPYGEARDDFAIFADLAERLGARDAFTEGRTVRQWLEHL
ECCCCCCCCCCCEEEEHHHCCCCCCCCCCHHHHHHHHHHHHCCCHHHCCCHHHHHHHHHH
YEPTRLGLVQLNLPAPSFEDFWESSGILVPQGPDDGGNLRAFREDPLASPLETPSGKLEI
CCCCCEEEEEEECCCCCHHHHHCCCCEEEECCCCCCCCEEEECCCCCCCCCCCCCCCCHH
FSETIASFGEADCPGHPAWLGSGYLPTESAPLVLVSNQPRTRLHSQLDFGGHSGSGKHRG
HHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCHHHHHHHCCCCCCCCCCCCCC
REIASMHPKDAAERGIADGDIVRLFNERGACLAAIALTEDIRPGVIQLPTGAWYDPADPT
CHHHHCCCHHHHHHCCCCCHHHHHHCCCCCEEEEEEHHHCCCCCEEECCCCCCCCCCCCC
EEKTLCVHGNPNVLTEDVGTSALAQGCTGQLTTVEVERFDGNLPPIRAYDPPLSLPAPAS
CCCEEEEECCCCEEHHHCCHHHHHCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCCCCHH
HLDG
HCCC
>Mature Secondary Structure
MRDSRFGNPERESEVPFKPHSSHWGVFSARMIDGELEVRPYEGDPDPNQIIENFPGALRH
CCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCEEEEECCCCCCCHHHHHHHCCHHHHH
RARIAQPMVRRGWLERGPGPDEKRGQDEFVPMAWQEVLDLLGRELVRVRDGFGPEAIFGG
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEECC
SYGWSSAGRFHHAQSQIHRFLNIACGGYVRSVTSYSSGSSQVLIPHILGNHEELAKHNVT
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEHHHHCCHHHHHHCCCC
WEQVEKDSEIVIAFGGMALKNSMVAGGGISKHVERGVMQRAAARGCEFILVSPLASDLPE
HHHHCCCCCEEEEECCHHHHCCEECCCCHHHHHHHHHHHHHHHCCCCEEEECCHHHCCCH
EARPEWVSLIPASDTALMMAMVHTLVVEGRHDRAFLERYTVGWPTFERYLLGEADGIPKD
HHCCCEEEEECCCHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCHHHHHHHCCCCCCCCC
AHWAAPLTGVPADAIMALARRLHGKRALVVVSHSLQRARYGEQPVWMGMVLAAALGQIGL
CCCCCCCCCCCHHHHHHHHHHHCCCEEEEEEEHHHHHHHCCCCCHHHHHHHHHHHHHHCC
SGGGYAYPLGAIAYYGRRKNAVKLPTLSQGSNSVREFIPVARIADMLLGPGEAYRFNGKT
CCCCCCCHHHHHHHHCCCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEECCCE
LTYPEIKLIYWAGGNPFHHHQDLNRLKKAFAAVDTLVVHELAWTATARHADIVLPCTMTL
EECCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEE
ERDDIGGSSNDPLLVPMRQIAPPYGEARDDFAIFADLAERLGARDAFTEGRTVRQWLEHL
ECCCCCCCCCCCEEEEHHHCCCCCCCCCCHHHHHHHHHHHHCCCHHHCCCHHHHHHHHHH
YEPTRLGLVQLNLPAPSFEDFWESSGILVPQGPDDGGNLRAFREDPLASPLETPSGKLEI
CCCCCEEEEEEECCCCCHHHHHCCCCEEEECCCCCCCCEEEECCCCCCCCCCCCCCCCHH
FSETIASFGEADCPGHPAWLGSGYLPTESAPLVLVSNQPRTRLHSQLDFGGHSGSGKHRG
HHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCHHHHHHHCCCCCCCCCCCCCC
REIASMHPKDAAERGIADGDIVRLFNERGACLAAIALTEDIRPGVIQLPTGAWYDPADPT
CHHHHCCCHHHHHHCCCCCHHHHHHCCCCCEEEEEEHHHCCCCCEEECCCCCCCCCCCCC
EEKTLCVHGNPNVLTEDVGTSALAQGCTGQLTTVEVERFDGNLPPIRAYDPPLSLPAPAS
CCCEEEEECCCCEEHHHCCHHHHHCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCCCCHH
HLDG
HCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: A Spontaneous Oxidation Product Of Biotin, D-Biotin D-Sulfoxide (Bso Or Bds) [C]

Specific reaction: Reduces A Spontaneous Oxidation Product Of Biotin, D-Biotin D-Sulfoxide (Bso Or Bds), Back To Biotin. [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8645727; 8534974; 7625833; 8658134 [H]