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The map label for this gene is hmrR2 [H]

Identifier: 220914730

GI number: 220914730

Start: 71860

End: 72309

Strand: Reverse

Name: hmrR2 [H]

Synonym: Mnod_7842

Alternate gene names: 220914730

Gene position: 72309-71860 (Counterclockwise)

Preceding gene: 220914731

Following gene: 220914727

Centisome position: 15.79

GC content: 60.22

Gene sequence:

>450_bases
ATGAACATAGGACAGGCAGCCAAGGCGTCCGGCGTTTCGGCCAAGATGATCCGCTACTACGAGCAGACCGGCCTCATACC
GCAGGCCGACCGGAAGGCTTCCGGGTATCGCGACTATTCCGACGTCGACGTGCACATGCTGCGCTTCATCCGCCGCGCAC
GCGGCCTCGGCTTCTCCGTCGCCAAGATCAATGAGCTGCTGGGATTGTGGCGAGATGAATCCCGGCAGAGCGCCGAGGTC
AAGCGGTTGGCGCAGGCCCACATCGACGAGCTCGAAAGGAAGATCAAGGGTCTTCAGGACATCGAGCATACGCTGACGAT
GCTCGTCAATGCCTGCGAAGGCGACCATCGTCCGCATTGCCCGATCCTCAAGCACCTCGAGAACGGCGAGGATAATGAAG
ATCTGTCAATTCACCCGCGCAAGGGCGCGGTTGCTGGCTTGGCTTATTGA

Upstream 100 bases:

>100_bases
GCTGGGCAACGCGCTTCGGCTCCGCCGCTTCAAGGTTGCGCACTGACAACGGCAGCAGCCGGCCGTTTCGGGCCGGCTGT
GTCGCGAAGGAAGATTACTC

Downstream 100 bases:

>100_bases
TCGGCCGCATCGGCAAACCGGAAGAGAAGTACCGCCCAGAACCCGCAACCGACACCCTGGTCAGCCAAGCCTCCTAACCG
TCCACAAAAACGGTTCTTCC

Product: transcriptional regulator, MerR family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 149; Mature: 149

Protein sequence:

>149_residues
MNIGQAAKASGVSAKMIRYYEQTGLIPQADRKASGYRDYSDVDVHMLRFIRRARGLGFSVAKINELLGLWRDESRQSAEV
KRLAQAHIDELERKIKGLQDIEHTLTMLVNACEGDHRPHCPILKHLENGEDNEDLSIHPRKGAVAGLAY

Sequences:

>Translated_149_residues
MNIGQAAKASGVSAKMIRYYEQTGLIPQADRKASGYRDYSDVDVHMLRFIRRARGLGFSVAKINELLGLWRDESRQSAEV
KRLAQAHIDELERKIKGLQDIEHTLTMLVNACEGDHRPHCPILKHLENGEDNEDLSIHPRKGAVAGLAY
>Mature_149_residues
MNIGQAAKASGVSAKMIRYYEQTGLIPQADRKASGYRDYSDVDVHMLRFIRRARGLGFSVAKINELLGLWRDESRQSAEV
KRLAQAHIDELERKIKGLQDIEHTLTMLVNACEGDHRPHCPILKHLENGEDNEDLSIHPRKGAVAGLAY

Specific function: Transcriptional regulator involved in acid tolerance. Binds copper [H]

COG id: COG0789

COG function: function code K; Predicted transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH merR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786695, Length=126, Percent_Identity=40.4761904761905, Blast_Score=105, Evalue=1e-24,
Organism=Escherichia coli, GI1789687, Length=130, Percent_Identity=38.4615384615385, Blast_Score=85, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011789
- InterPro:   IPR009061
- InterPro:   IPR000551
- InterPro:   IPR015358 [H]

Pfam domain/function: PF00376 MerR; PF09278 MerR-DNA-bind [H]

EC number: NA

Molecular weight: Translated: 16762; Mature: 16762

Theoretical pI: Translated: 8.25; Mature: 8.25

Prosite motif: PS00552 HTH_MERR_1 ; PS50937 HTH_MERR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIGQAAKASGVSAKMIRYYEQTGLIPQADRKASGYRDYSDVDVHMLRFIRRARGLGFSV
CCCCCCHHHCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHH
AKINELLGLWRDESRQSAEVKRLAQAHIDELERKIKGLQDIEHTLTMLVNACEGDHRPHC
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
PILKHLENGEDNEDLSIHPRKGAVAGLAY
HHHHHHCCCCCCCCCEECCCCCCCCCCCC
>Mature Secondary Structure
MNIGQAAKASGVSAKMIRYYEQTGLIPQADRKASGYRDYSDVDVHMLRFIRRARGLGFSV
CCCCCCHHHCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHH
AKINELLGLWRDESRQSAEVKRLAQAHIDELERKIKGLQDIEHTLTMLVNACEGDHRPHC
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
PILKHLENGEDNEDLSIHPRKGAVAGLAY
HHHHHHCCCCCCCCCEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11481431 [H]