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The map label for this gene is ygeV [H]

Identifier: 220905605

GI number: 220905605

Start: 2826042

End: 2827502

Strand: Reverse

Name: ygeV [H]

Synonym: Ddes_2345

Alternate gene names: 220905605

Gene position: 2827502-2826042 (Counterclockwise)

Preceding gene: 220905612

Following gene: 220905602

Centisome position: 98.4

GC content: 56.67

Gene sequence:

>1461_bases
ATGACATTGTCCTCTCAACCTCTTTTTTTAAACGTGGAAAGAAGTTATCGCCGTTTACTCAATCATTTACCGGGGATGGC
CTATCGTTGCCGCATTCTGGGCGATACCCGTGATGAAAAGAAAAACCTGATTTACGAGTTGGAATTCGTCAGCCGGGGCT
GTTACGACCTTTTGGGCATCACTGCCGGGGACATGCTGATGGGGCATAACAACACCATTGAGCGCATGACCCACCCCGAT
GACCTTGAGCGGACCCGAAAAACCATACGCGACAGTATTGTCGCGCGGGAATCCTATCAGGTGATGTACCGCCTTCTGTT
GCCGTCGGGCCGGATAAAATGGCTCTGGGACCAGGGCGAATGCGTGGATGATGAAGAGGGCTGTCCGCAATATCTGGAAG
GCCTGATCATGGACGTGAGCGAGCAGAAGTTTCAGGAACTGGCCCTTCGTGAAGAAAATCGCGCATTGCGGGAATCTGTG
GTCAACCTGCGCGGCCTGGGTTCAATGGTCGGGCAGAGCGAACCCATGCGCCAGCTTTACAGCCAGATCCTGCGGGCAGC
GGAAACGGATTCAAACGTCATCATTTACGGTGAAACAGGCTGTGGCAAAGACCTTGTGGCACGCAGCATTCATGAATACA
GCGGGCGCAAGGGCAACTATGTGCCTGTCAACTGCGGCGCCATTCCCGAGCAGTTGCTGGAAAGCGAGTTTTTTGGCCAC
GTAAAAGGGGCTTTTTCCGGTGCGCACGCCAATAAGGACGGTTATATCGGGGCGGCCCACGGCGGCACGCTGTTTCTGGA
CGAAATAGGCGAACTGCCGCTGCATCTTCAGGTCAAGCTGCTGCGGGCCATTGAAAACAAGATGTACACCCCTGTGGGCG
ACAACAAGCCGCGCAAGTCTTCATTCAGGCTTATTGCGGCCACCAACCAGGATCTTGCGCGCATGGTGCGCGAAAAGAAA
ATGCGCTCGGACTTTTATTACAGGGTGCATGTGCTTTCCATTACCCTGCCGCCGCTGCGTGAGCGGCAAGGTGATATTCC
CCTGCTTGTGGATGCCTGGATGGAACGGCGCAAGGTGTTTCTGGTGCTGCCGCGGCATGTGCGCCTGGCCATGGAGCGTT
ACGACTGGCCCGGCAACGTGCGCGAACTTTACAATTTTCTGGACAGGTACATGGCCTTTGGCGAAGAAGCCCTGTCTTCG
CTGGGCGACCTGCATGCCGATGCCGGGCTGGTGCTTACCGTGGAGGCAGAGGCGGCCACCCTGGATCAGGCCGTCATGCG
CCTGGAAGAACGCATGATCCGGCAGGCCCTGGACCAGTGTCGCTGGCAGAAGGGCCGGGCGGCACATGCACTGGGACTTA
ACCTGCGCACACTGCAACGTAAAATGAAGCGGCTTGGCATGAGCGAACCAAGAACGGGCACCTTGATGCTTGAGGGCGGC
CCGCCTCGGAAAGAACAGTAA

Upstream 100 bases:

>100_bases
CACGCCGGAGCTTGTGTTTTCTGGCACATCGGGCGATTATCGCTTACGAAACACGACATTTTTGTCGCGTATGGCGACAA
AAATTGTAAAAGGTGATGCC

Downstream 100 bases:

>100_bases
GCGTTTGCGTGGCGCTTCCGGTTACCCTGTGCGCGGGGATGCGGATCGTGCCGGGCATGAAACGGCGCGGGCGACCGCGC
CGCATGTTTTGCGGCGGGTC

Product: Fis family sigma-54 specific transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 486; Mature: 485

Protein sequence:

>486_residues
MTLSSQPLFLNVERSYRRLLNHLPGMAYRCRILGDTRDEKKNLIYELEFVSRGCYDLLGITAGDMLMGHNNTIERMTHPD
DLERTRKTIRDSIVARESYQVMYRLLLPSGRIKWLWDQGECVDDEEGCPQYLEGLIMDVSEQKFQELALREENRALRESV
VNLRGLGSMVGQSEPMRQLYSQILRAAETDSNVIIYGETGCGKDLVARSIHEYSGRKGNYVPVNCGAIPEQLLESEFFGH
VKGAFSGAHANKDGYIGAAHGGTLFLDEIGELPLHLQVKLLRAIENKMYTPVGDNKPRKSSFRLIAATNQDLARMVREKK
MRSDFYYRVHVLSITLPPLRERQGDIPLLVDAWMERRKVFLVLPRHVRLAMERYDWPGNVRELYNFLDRYMAFGEEALSS
LGDLHADAGLVLTVEAEAATLDQAVMRLEERMIRQALDQCRWQKGRAAHALGLNLRTLQRKMKRLGMSEPRTGTLMLEGG
PPRKEQ

Sequences:

>Translated_486_residues
MTLSSQPLFLNVERSYRRLLNHLPGMAYRCRILGDTRDEKKNLIYELEFVSRGCYDLLGITAGDMLMGHNNTIERMTHPD
DLERTRKTIRDSIVARESYQVMYRLLLPSGRIKWLWDQGECVDDEEGCPQYLEGLIMDVSEQKFQELALREENRALRESV
VNLRGLGSMVGQSEPMRQLYSQILRAAETDSNVIIYGETGCGKDLVARSIHEYSGRKGNYVPVNCGAIPEQLLESEFFGH
VKGAFSGAHANKDGYIGAAHGGTLFLDEIGELPLHLQVKLLRAIENKMYTPVGDNKPRKSSFRLIAATNQDLARMVREKK
MRSDFYYRVHVLSITLPPLRERQGDIPLLVDAWMERRKVFLVLPRHVRLAMERYDWPGNVRELYNFLDRYMAFGEEALSS
LGDLHADAGLVLTVEAEAATLDQAVMRLEERMIRQALDQCRWQKGRAAHALGLNLRTLQRKMKRLGMSEPRTGTLMLEGG
PPRKEQ
>Mature_485_residues
TLSSQPLFLNVERSYRRLLNHLPGMAYRCRILGDTRDEKKNLIYELEFVSRGCYDLLGITAGDMLMGHNNTIERMTHPDD
LERTRKTIRDSIVARESYQVMYRLLLPSGRIKWLWDQGECVDDEEGCPQYLEGLIMDVSEQKFQELALREENRALRESVV
NLRGLGSMVGQSEPMRQLYSQILRAAETDSNVIIYGETGCGKDLVARSIHEYSGRKGNYVPVNCGAIPEQLLESEFFGHV
KGAFSGAHANKDGYIGAAHGGTLFLDEIGELPLHLQVKLLRAIENKMYTPVGDNKPRKSSFRLIAATNQDLARMVREKKM
RSDFYYRVHVLSITLPPLRERQGDIPLLVDAWMERRKVFLVLPRHVRLAMERYDWPGNVRELYNFLDRYMAFGEEALSSL
GDLHADAGLVLTVEAEAATLDQAVMRLEERMIRQALDQCRWQKGRAAHALGLNLRTLQRKMKRLGMSEPRTGTLMLEGGP
PRKEQ

Specific function: Unknown

COG id: COG2204

COG function: function code T; Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1789233, Length=316, Percent_Identity=44.9367088607595, Blast_Score=239, Evalue=3e-64,
Organism=Escherichia coli, GI1789087, Length=336, Percent_Identity=41.0714285714286, Blast_Score=223, Evalue=2e-59,
Organism=Escherichia coli, GI1788550, Length=343, Percent_Identity=36.1516034985423, Blast_Score=220, Evalue=1e-58,
Organism=Escherichia coli, GI87082117, Length=342, Percent_Identity=38.5964912280702, Blast_Score=216, Evalue=2e-57,
Organism=Escherichia coli, GI1790437, Length=308, Percent_Identity=39.9350649350649, Blast_Score=208, Evalue=6e-55,
Organism=Escherichia coli, GI87082152, Length=318, Percent_Identity=38.9937106918239, Blast_Score=197, Evalue=1e-51,
Organism=Escherichia coli, GI1790299, Length=329, Percent_Identity=36.7781155015198, Blast_Score=195, Evalue=6e-51,
Organism=Escherichia coli, GI1788905, Length=242, Percent_Identity=42.5619834710744, Blast_Score=195, Evalue=6e-51,
Organism=Escherichia coli, GI1786524, Length=317, Percent_Identity=39.1167192429022, Blast_Score=195, Evalue=6e-51,
Organism=Escherichia coli, GI87081872, Length=316, Percent_Identity=34.4936708860759, Blast_Score=171, Evalue=9e-44,
Organism=Escherichia coli, GI1787583, Length=324, Percent_Identity=32.0987654320988, Blast_Score=155, Evalue=4e-39,
Organism=Escherichia coli, GI1789828, Length=281, Percent_Identity=35.5871886120996, Blast_Score=147, Evalue=1e-36,
Organism=Escherichia coli, GI87081858, Length=297, Percent_Identity=30.3030303030303, Blast_Score=112, Evalue=4e-26,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR003018
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR000014
- InterPro:   IPR002078 [H]

Pfam domain/function: PF02954 HTH_8; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 55560; Mature: 55429

Theoretical pI: Translated: 8.07; Mature: 8.07

Prosite motif: PS50113 PAC ; PS00676 SIGMA54_INTERACT_2 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLSSQPLFLNVERSYRRLLNHLPGMAYRCRILGDTRDEKKNLIYELEFVSRGCYDLLGI
CCCCCCCEEEECHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCEEEEHHHHCCHHHHHHC
TAGDMLMGHNNTIERMTHPDDLERTRKTIRDSIVARESYQVMYRLLLPSGRIKWLWDQGE
CCCCEEECCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCC
CVDDEEGCPQYLEGLIMDVSEQKFQELALREENRALRESVVNLRGLGSMVGQSEPMRQLY
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
SQILRAAETDSNVIIYGETGCGKDLVARSIHEYSGRKGNYVPVNCGAIPEQLLESEFFGH
HHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHHH
VKGAFSGAHANKDGYIGAAHGGTLFLDEIGELPLHLQVKLLRAIENKMYTPVGDNKPRKS
HHHHCCCCCCCCCCEEEECCCCEEEHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCC
SFRLIAATNQDLARMVREKKMRSDFYYRVHVLSITLPPLRERQGDIPLLVDAWMERRKVF
CEEEEEECCHHHHHHHHHHHHHCCCEEEEEEEEEECCCHHHCCCCCCCHHHHHHHCCEEE
LVLPRHVRLAMERYDWPGNVRELYNFLDRYMAFGEEALSSLGDLHADAGLVLTVEAEAAT
EECCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECHHHH
LDQAVMRLEERMIRQALDQCRWQKGRAAHALGLNLRTLQRKMKRLGMSEPRTGTLMLEGG
HHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCHHHHHHHHHHCCCCCCCCCEEEECCC
PPRKEQ
CCCCCC
>Mature Secondary Structure 
TLSSQPLFLNVERSYRRLLNHLPGMAYRCRILGDTRDEKKNLIYELEFVSRGCYDLLGI
CCCCCCEEEECHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCEEEEHHHHCCHHHHHHC
TAGDMLMGHNNTIERMTHPDDLERTRKTIRDSIVARESYQVMYRLLLPSGRIKWLWDQGE
CCCCEEECCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCC
CVDDEEGCPQYLEGLIMDVSEQKFQELALREENRALRESVVNLRGLGSMVGQSEPMRQLY
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
SQILRAAETDSNVIIYGETGCGKDLVARSIHEYSGRKGNYVPVNCGAIPEQLLESEFFGH
HHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHHH
VKGAFSGAHANKDGYIGAAHGGTLFLDEIGELPLHLQVKLLRAIENKMYTPVGDNKPRKS
HHHHCCCCCCCCCCEEEECCCCEEEHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCC
SFRLIAATNQDLARMVREKKMRSDFYYRVHVLSITLPPLRERQGDIPLLVDAWMERRKVF
CEEEEEECCHHHHHHHHHHHHHCCCEEEEEEEEEECCCHHHCCCCCCCHHHHHHHCCEEE
LVLPRHVRLAMERYDWPGNVRELYNFLDRYMAFGEEALSSLGDLHADAGLVLTVEAEAAT
EECCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECHHHH
LDQAVMRLEERMIRQALDQCRWQKGRAAHALGLNLRTLQRKMKRLGMSEPRTGTLMLEGG
HHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCHHHHHHHHHHCCCCCCCCCEEEECCC
PPRKEQ
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]