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The map label for this gene is yfnC [H]

Identifier: 220905601

GI number: 220905601

Start: 2819657

End: 2820910

Strand: Direct

Name: yfnC [H]

Synonym: Ddes_2341

Alternate gene names: 220905601

Gene position: 2819657-2820910 (Clockwise)

Preceding gene: 220905595

Following gene: 220905603

Centisome position: 98.13

GC content: 60.29

Gene sequence:

>1254_bases
ATGGACAAGAAAAAAATATCCCTTGTATCGCTCGGTCACTTATCGTGCGACGTCAATGGCGGGGCATTACCCGCCATTCT
GCCCTTCCTGCGCACCCACTACGGGTTGACCTACCAGGCCACGGGCGGCCTCATGTTTGCTTACTCCTGCCTGTCGTCGA
TCATACAGCCGCTTTTCGGCCTTATGGCAGACAGGCTCTCCAAGCCCTGGCTCATCCCCCTCGGCGTGTTTCTGGCAGGC
ATGGGGCTGGCGGCAGTGGGCTTCATGTCCAGCTACTGGGCCATTTTTGCGGCCATCGGCCTAAGCGGCGTGGGCGCAGC
CCTTTTTCACCCCGAGGGAGCGCGCTTTGCCAACAAGGTGTCCGGAAAAAGCAAAGGCACCGGCATGAGTATATTTTCCA
TCGGCGGCAATGCGGGCTTTGTTATCGGGCCGCTGCTGGCAACCTTTTTCCTGAGCTGGCTGGGCATGCCCGGAACCTTT
ATTTTCGGCCTGCTGGCTACAGTCATGGCCTCCATTCTGCTGCTGCTCATCATGCGTATGGTTGCGCCAGAAGCTGCTGC
CGCAGCCCAGAGAACCGCCGAAGCCGCTTACGGAACGCAGCAGGCCGGGGCACAGGGCAAAGGAGTCCAGGCGCGCCGGG
GCGGCATACCGGTGGCAGACGCCGGGACCGAAGAAGCCCCGCAAAACAACTGGCATGAATTTTCAAAGCTTACCGGGGCC
ATCATTGCGCGCTCCGTTCTTTTTGTGGGGTTCAACACCTTTATCCCGCTGTACTGGGTAAACGGCTTTGGGCAGAGTAA
AACCGCCGGAGCCATTGCCCTGACCATTTTCTGTACCTTCGGCGTCGCCAGCAACATATTGGGCGGAGTACTGGCCGACA
GGCACGGCTTCAGGGCCATCGTGCGCATGGGCTTCGCCCTTATGACGCCCGCGGTGCTGGCTTTCGGGCTGCTGCCCAAT
CTCTATGCCGCCTACGCCCTGCTGCCCCTGCTCGGCTTTGTGCTGTATGCGCCTTTCAGTTCTCTGGTGGTTCTGGGACA
GACATATCTTGCCCGCAATATCGGCTTTGCTTCGGGCGTTACCCTGGGGCTGGCCACCAGCCTGGGAGGCGTGTTCGCGC
CGCTGCTGGGCTGGATTGCCGACAACCACGGTCTGCCGCGCACCTTTCAGTGCCTGGCCGTGGTAGCTTTTATCGGCACG
GTATTCGCCTTTGCCCTGCGCGAATACACGGCAAAAACTCCGGCCAGGGCATAG

Upstream 100 bases:

>100_bases
CGGGACGTTGCGTCAACGCGGCCCGGTCCCGGCCGCGCACTGAAAGACGGGCGTTTCCGGGCCACTTGGTTTTGTCATTC
CCTTGGTGTAGCGTGCGCGC

Downstream 100 bases:

>100_bases
CCCCTCCGCCAGCCGCAGTTACGAACATTCAAAAGGCCCCTGCTCCGGAAATGCCGGTGCAGGGGCCTTTTTTGCGTCCA
TACCGGCAAAATCCCGTCCA

Product: major facilitator superfamily protein

Products: fosmidomycin [Periplasm]; Proton [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 417; Mature: 417

Protein sequence:

>417_residues
MDKKKISLVSLGHLSCDVNGGALPAILPFLRTHYGLTYQATGGLMFAYSCLSSIIQPLFGLMADRLSKPWLIPLGVFLAG
MGLAAVGFMSSYWAIFAAIGLSGVGAALFHPEGARFANKVSGKSKGTGMSIFSIGGNAGFVIGPLLATFFLSWLGMPGTF
IFGLLATVMASILLLLIMRMVAPEAAAAAQRTAEAAYGTQQAGAQGKGVQARRGGIPVADAGTEEAPQNNWHEFSKLTGA
IIARSVLFVGFNTFIPLYWVNGFGQSKTAGAIALTIFCTFGVASNILGGVLADRHGFRAIVRMGFALMTPAVLAFGLLPN
LYAAYALLPLLGFVLYAPFSSLVVLGQTYLARNIGFASGVTLGLATSLGGVFAPLLGWIADNHGLPRTFQCLAVVAFIGT
VFAFALREYTAKTPARA

Sequences:

>Translated_417_residues
MDKKKISLVSLGHLSCDVNGGALPAILPFLRTHYGLTYQATGGLMFAYSCLSSIIQPLFGLMADRLSKPWLIPLGVFLAG
MGLAAVGFMSSYWAIFAAIGLSGVGAALFHPEGARFANKVSGKSKGTGMSIFSIGGNAGFVIGPLLATFFLSWLGMPGTF
IFGLLATVMASILLLLIMRMVAPEAAAAAQRTAEAAYGTQQAGAQGKGVQARRGGIPVADAGTEEAPQNNWHEFSKLTGA
IIARSVLFVGFNTFIPLYWVNGFGQSKTAGAIALTIFCTFGVASNILGGVLADRHGFRAIVRMGFALMTPAVLAFGLLPN
LYAAYALLPLLGFVLYAPFSSLVVLGQTYLARNIGFASGVTLGLATSLGGVFAPLLGWIADNHGLPRTFQCLAVVAFIGT
VFAFALREYTAKTPARA
>Mature_417_residues
MDKKKISLVSLGHLSCDVNGGALPAILPFLRTHYGLTYQATGGLMFAYSCLSSIIQPLFGLMADRLSKPWLIPLGVFLAG
MGLAAVGFMSSYWAIFAAIGLSGVGAALFHPEGARFANKVSGKSKGTGMSIFSIGGNAGFVIGPLLATFFLSWLGMPGTF
IFGLLATVMASILLLLIMRMVAPEAAAAAQRTAEAAYGTQQAGAQGKGVQARRGGIPVADAGTEEAPQNNWHEFSKLTGA
IIARSVLFVGFNTFIPLYWVNGFGQSKTAGAIALTIFCTFGVASNILGGVLADRHGFRAIVRMGFALMTPAVLAFGLLPN
LYAAYALLPLLGFVLYAPFSSLVVLGQTYLARNIGFASGVTLGLATSLGGVFAPLLGWIADNHGLPRTFQCLAVVAFIGT
VFAFALREYTAKTPARA

Specific function: Confers The Resistance Against Fosmidomycin. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily [H]

Homologues:

Organism=Escherichia coli, GI1786686, Length=399, Percent_Identity=28.0701754385965, Blast_Score=120, Evalue=1e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 43599; Mature: 43599

Theoretical pI: Translated: 10.17; Mature: 10.17

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKKKISLVSLGHLSCDVNGGALPAILPFLRTHYGLTYQATGGLMFAYSCLSSIIQPLFG
CCCCCEEEEEECCEEECCCCCCHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHHHHHH
LMADRLSKPWLIPLGVFLAGMGLAAVGFMSSYWAIFAAIGLSGVGAALFHPEGARFANKV
HHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCHHHHHHH
SGKSKGTGMSIFSIGGNAGFVIGPLLATFFLSWLGMPGTFIFGLLATVMASILLLLIMRM
CCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
VAPEAAAAAQRTAEAAYGTQQAGAQGKGVQARRGGIPVADAGTEEAPQNNWHEFSKLTGA
HCCHHHHHHHHHHHHHCCCHHCCCCCCCCCHHCCCCCCCCCCCCCCCCCHHHHHHHHHHH
IIARSVLFVGFNTFIPLYWVNGFGQSKTAGAIALTIFCTFGVASNILGGVLADRHGFRAI
HHHHHHHHHHHHHHHHHHEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VRMGFALMTPAVLAFGLLPNLYAAYALLPLLGFVLYAPFSSLVVLGQTYLARNIGFASGV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCH
TLGLATSLGGVFAPLLGWIADNHGLPRTFQCLAVVAFIGTVFAFALREYTAKTPARA
HHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MDKKKISLVSLGHLSCDVNGGALPAILPFLRTHYGLTYQATGGLMFAYSCLSSIIQPLFG
CCCCCEEEEEECCEEECCCCCCHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHHHHHH
LMADRLSKPWLIPLGVFLAGMGLAAVGFMSSYWAIFAAIGLSGVGAALFHPEGARFANKV
HHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCHHHHHHH
SGKSKGTGMSIFSIGGNAGFVIGPLLATFFLSWLGMPGTFIFGLLATVMASILLLLIMRM
CCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
VAPEAAAAAQRTAEAAYGTQQAGAQGKGVQARRGGIPVADAGTEEAPQNNWHEFSKLTGA
HCCHHHHHHHHHHHHHCCCHHCCCCCCCCCHHCCCCCCCCCCCCCCCCCHHHHHHHHHHH
IIARSVLFVGFNTFIPLYWVNGFGQSKTAGAIALTIFCTFGVASNILGGVLADRHGFRAI
HHHHHHHHHHHHHHHHHHEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VRMGFALMTPAVLAFGLLPNLYAAYALLPLLGFVLYAPFSSLVVLGQTYLARNIGFASGV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCH
TLGLATSLGGVFAPLLGWIADNHGLPRTFQCLAVVAFIGTVFAFALREYTAKTPARA
HHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: fosmidomycin [Cytoplasm]; Proton [Periplasm] [C]

Specific reaction: fosmidomycin [Cytoplasm] + Proton [Periplasm] = fosmidomycin [Periplasm] + Proton [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9141694; 9384377 [H]