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The map label for this gene is asrB [H]

Identifier: 220905365

GI number: 220905365

Start: 2533809

End: 2534669

Strand: Direct

Name: asrB [H]

Synonym: Ddes_2103

Alternate gene names: 220905365

Gene position: 2533809-2534669 (Clockwise)

Preceding gene: 220905364

Following gene: 220905366

Centisome position: 88.18

GC content: 58.54

Gene sequence:

>861_bases
ATGCTGCGTGAAATAACGGCCCGTCCGCAACCCACGGGCAACCCCTATCTGCCTATGACCGCCACCGTGGCTGAAGTTAT
TCAGGAAACCGGCAATATCCGCACCCTGCGCGTGGTGCTGGACGATACCGAAACCATGAAGAATTTCGTTCACGAACCGG
GGCAGGTGGGGCAACTTTCTGTTTTCGGCGCGGGCGAATCCACCTTTGTTATCAACTCGCCGCCGTCACAGAAAGACTAT
CTGCAATTCTCGGTCATGCAGGCCGGAGAAGTGACCGCAGCCATCCACCGCCTGTCGCCCGGCGACAAGGTCGGTGTACG
TGCACCGCTGGGTAACTTCTTTCCCTACAACGACTGGAAGGGCAAAGACGTCTTCTTTGTGGGTGGCGGCATCGGCATGG
CCCCCATCCGCACCATCATGCTGCACGTGCTGGAAAACAGGAAAGACTACGGCAAGGTGAGCCTGCTTTACGGCGCGCGC
ACCCCACGCGACATGGCCTTCAGCTACGAAGCAGAAGAATGGCTGCGCCGCGATGACCTGGACTGCACACTCTGCATCGA
TGCGCCCTTTGAGGGTTGGGAACACAAAGTGGGCCTCATCCCTAACGTGCTCACCGAACTGAACCCCGACCCAAAAAACT
GCGTGGCCGTGCTCTGCGGGCCGCCCATCATGATCAAGTTTACCGTGCAGGCGCTGGAAAAGCTGAACTTCGCCCCGGAA
AACATCGTGACCACACTGGAAAAGCGCATGAAATGCGGCATCGGCATCTGCGGACGCTGCAATATCGGCGGGCGCTACGT
CTGTGTGGACGGCCCGGTGTTTACCTGGAAAGAACTTCAGGAACTGCCGCCGGAACTGTAG

Upstream 100 bases:

>100_bases
CCCCGCAGCCGCAGCCAAGGCCGCTGAAGTCCGGACCGAACAAAACGCTCCGGCTGCAGCCGCTGCCAAAACCGCACCCA
AGGCTCCGGCCAAGGGCGGC

Downstream 100 bases:

>100_bases
TTTCCTGCCAGTAATCCTTTTTTAATAATTCATTGCGAGAGAGGCCCCTTTTTGAAAAAAGGGGTCTCTCTCGCGCTCTC
TCCACCAAAAACTTTTATAG

Product: oxidoreductase FAD/NAD(P)-binding domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 286; Mature: 286

Protein sequence:

>286_residues
MLREITARPQPTGNPYLPMTATVAEVIQETGNIRTLRVVLDDTETMKNFVHEPGQVGQLSVFGAGESTFVINSPPSQKDY
LQFSVMQAGEVTAAIHRLSPGDKVGVRAPLGNFFPYNDWKGKDVFFVGGGIGMAPIRTIMLHVLENRKDYGKVSLLYGAR
TPRDMAFSYEAEEWLRRDDLDCTLCIDAPFEGWEHKVGLIPNVLTELNPDPKNCVAVLCGPPIMIKFTVQALEKLNFAPE
NIVTTLEKRMKCGIGICGRCNIGGRYVCVDGPVFTWKELQELPPEL

Sequences:

>Translated_286_residues
MLREITARPQPTGNPYLPMTATVAEVIQETGNIRTLRVVLDDTETMKNFVHEPGQVGQLSVFGAGESTFVINSPPSQKDY
LQFSVMQAGEVTAAIHRLSPGDKVGVRAPLGNFFPYNDWKGKDVFFVGGGIGMAPIRTIMLHVLENRKDYGKVSLLYGAR
TPRDMAFSYEAEEWLRRDDLDCTLCIDAPFEGWEHKVGLIPNVLTELNPDPKNCVAVLCGPPIMIKFTVQALEKLNFAPE
NIVTTLEKRMKCGIGICGRCNIGGRYVCVDGPVFTWKELQELPPEL
>Mature_286_residues
MLREITARPQPTGNPYLPMTATVAEVIQETGNIRTLRVVLDDTETMKNFVHEPGQVGQLSVFGAGESTFVINSPPSQKDY
LQFSVMQAGEVTAAIHRLSPGDKVGVRAPLGNFFPYNDWKGKDVFFVGGGIGMAPIRTIMLHVLENRKDYGKVSLLYGAR
TPRDMAFSYEAEEWLRRDDLDCTLCIDAPFEGWEHKVGLIPNVLTELNPDPKNCVAVLCGPPIMIKFTVQALEKLNFAPE
NIVTTLEKRMKCGIGICGRCNIGGRYVCVDGPVFTWKELQELPPEL

Specific function: This enzyme catalyzes the hydrogen sulfide production from sulfite. It is strictly anaerobic. It is regulated by electron acceptors rather than by cysteine [H]

COG id: COG0543

COG function: function code HC; 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding FR-type domain [H]

Homologues:

Organism=Homo sapiens, GI84875541, Length=174, Percent_Identity=28.735632183908, Blast_Score=73, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24662938, Length=173, Percent_Identity=27.7456647398844, Blast_Score=72, Evalue=5e-13,
Organism=Drosophila melanogaster, GI281366101, Length=173, Percent_Identity=27.7456647398844, Blast_Score=72, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24662934, Length=173, Percent_Identity=27.7456647398844, Blast_Score=72, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012165
- InterPro:   IPR019480
- InterPro:   IPR017927
- InterPro:   IPR008333
- InterPro:   IPR001433
- InterPro:   IPR017938
- InterPro:   IPR014260 [H]

Pfam domain/function: PF10418 DHODB_Fe-S_bind; PF00970 FAD_binding_6; PF00175 NAD_binding_1 [H]

EC number: NA

Molecular weight: Translated: 31732; Mature: 31732

Theoretical pI: Translated: 5.43; Mature: 5.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLREITARPQPTGNPYLPMTATVAEVIQETGNIRTLRVVLDDTETMKNFVHEPGQVGQLS
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCEEEEEEEECCHHHHHHHHCCCCCCCEEE
VFGAGESTFVINSPPSQKDYLQFSVMQAGEVTAAIHRLSPGDKVGVRAPLGNFFPYNDWK
EEECCCEEEEEECCCCCCHHEEEEECCCCCHHHHHHHCCCCCCCEEECCCCCCCCCCCCC
GKDVFFVGGGIGMAPIRTIMLHVLENRKDYGKVSLLYGARTPRDMAFSYEAEEWLRRDDL
CCEEEEECCCCCHHHHHHHHHHHHHCCCCCCCEEEEECCCCCHHHEEEECHHHHHHHCCC
DCTLCIDAPFEGWEHKVGLIPNVLTELNPDPKNCVAVLCGPPIMIKFTVQALEKLNFAPE
CEEEEECCCCCCCCCCCCCCHHHHHHCCCCHHHEEEEEECCCEEEEEEHHHHHHCCCCHH
NIVTTLEKRMKCGIGICGRCNIGGRYVCVDGPVFTWKELQELPPEL
HHHHHHHHHHHCCCCEEEECCCCCEEEEECCCCCCHHHHHHCCCCC
>Mature Secondary Structure
MLREITARPQPTGNPYLPMTATVAEVIQETGNIRTLRVVLDDTETMKNFVHEPGQVGQLS
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCEEEEEEEECCHHHHHHHHCCCCCCCEEE
VFGAGESTFVINSPPSQKDYLQFSVMQAGEVTAAIHRLSPGDKVGVRAPLGNFFPYNDWK
EEECCCEEEEEECCCCCCHHEEEEECCCCCHHHHHHHCCCCCCCEEECCCCCCCCCCCCC
GKDVFFVGGGIGMAPIRTIMLHVLENRKDYGKVSLLYGARTPRDMAFSYEAEEWLRRDDL
CCEEEEECCCCCHHHHHHHHHHHHHCCCCCCCEEEEECCCCCHHHEEEECHHHHHHHCCC
DCTLCIDAPFEGWEHKVGLIPNVLTELNPDPKNCVAVLCGPPIMIKFTVQALEKLNFAPE
CEEEEECCCCCCCCCCCCCCHHHHHHCCCCHHHEEEEEECCCEEEEEEHHHHHHCCCCHH
NIVTTLEKRMKCGIGICGRCNIGGRYVCVDGPVFTWKELQELPPEL
HHHHHHHHHHHCCCCEEEECCCCCEEEEECCCCCCHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1704886; 11677609 [H]