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The map label for this gene is acuB [H]

Identifier: 220905178

GI number: 220905178

Start: 2308633

End: 2309292

Strand: Direct

Name: acuB [H]

Synonym: Ddes_1916

Alternate gene names: 220905178

Gene position: 2308633-2309292 (Clockwise)

Preceding gene: 220905175

Following gene: 220905179

Centisome position: 80.34

GC content: 58.79

Gene sequence:

>660_bases
ATGCCCGTACAAAACTGGATGACCACCGATGTTGTGAGCGTCACCCCGGAGACGTCTCTGCTAAAGGTGGGCAAGCTCAT
GAAGGACCACCATGTCCGCCGCCTGCCCGTGCTTGATGACAAGGGCCGTGTGGTCGGCATCATTTCTGACCGTGACGTGC
GTGACGCCTCCCCCTCCAAGGCCACCACGCTCGACATGTACGAAATGCACTATCTGCTCGCCGAGCTCAAGGCCAAAAAC
ATTATGACGGCCAACCCCATGACCGTCAAACCTTCCGACACGGTAGAGCAGGCGGCCCTGATCATGCTCGACAACAAGAT
CGGCGGGTTGCCCGTGGTGGAAGACAGCGGCAAGCTGGTGGGCATTATTTCAGACCACGATGTTTTCAAGGCCCTGGTCG
ACATCACCGGCGCGCGCCTTGGCGGCCTCCAGTTCGCCATAGAGCTGCCCGACCTGCCCGGCACGGCCCGCCCCCTCTTT
GACCTGCTGCGCGCCCACAACGCGCGCCTGCTGTCTGTTTTGACCGTAAGTAACGAAGATGGCAATCGTCACATATTTAT
CCGGGTGCGTGATCTTAAAAACGCCGCGGCCGAAAATACCCTGATGGAAGAGGTTGCAAAGCTCGGCCGGGTGCTGTATT
GCATTCGGCAAAATGCCTGA

Upstream 100 bases:

>100_bases
GCACTTGTGCAGCATCCGCCTGTTGTTGTATAAAGAGAAAAAGGCCGCTGCCTTCCGCAGCCGCCCAACTCTGAAACGTA
TCGAAAAACCGGAGGGAAGC

Downstream 100 bases:

>100_bases
TCAGCTCAATCAAGATTGGCTCATCCTTTCAGGATCGCTGAAAAAAAATCTTGACTGAATCAGTGGGGCAGACCAAAAAA
AGCTGCCGGGGCTTGCCATC

Product: CBS domain containing membrane protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 219; Mature: 218

Protein sequence:

>219_residues
MPVQNWMTTDVVSVTPETSLLKVGKLMKDHHVRRLPVLDDKGRVVGIISDRDVRDASPSKATTLDMYEMHYLLAELKAKN
IMTANPMTVKPSDTVEQAALIMLDNKIGGLPVVEDSGKLVGIISDHDVFKALVDITGARLGGLQFAIELPDLPGTARPLF
DLLRAHNARLLSVLTVSNEDGNRHIFIRVRDLKNAAAENTLMEEVAKLGRVLYCIRQNA

Sequences:

>Translated_219_residues
MPVQNWMTTDVVSVTPETSLLKVGKLMKDHHVRRLPVLDDKGRVVGIISDRDVRDASPSKATTLDMYEMHYLLAELKAKN
IMTANPMTVKPSDTVEQAALIMLDNKIGGLPVVEDSGKLVGIISDHDVFKALVDITGARLGGLQFAIELPDLPGTARPLF
DLLRAHNARLLSVLTVSNEDGNRHIFIRVRDLKNAAAENTLMEEVAKLGRVLYCIRQNA
>Mature_218_residues
PVQNWMTTDVVSVTPETSLLKVGKLMKDHHVRRLPVLDDKGRVVGIISDRDVRDASPSKATTLDMYEMHYLLAELKAKNI
MTANPMTVKPSDTVEQAALIMLDNKIGGLPVVEDSGKLVGIISDHDVFKALVDITGARLGGLQFAIELPDLPGTARPLFD
LLRAHNARLLSVLTVSNEDGNRHIFIRVRDLKNAAAENTLMEEVAKLGRVLYCIRQNA

Specific function: Role in growth and sporulation on acetoin or butanediol. Involved in the breakdown of these compounds used as a carbon source [H]

COG id: COG0517

COG function: function code R; FOG: CBS domain

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR000644 [H]

Pfam domain/function: PF00571 CBS [H]

EC number: NA

Molecular weight: Translated: 24143; Mature: 24012

Theoretical pI: Translated: 7.17; Mature: 7.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPVQNWMTTDVVSVTPETSLLKVGKLMKDHHVRRLPVLDDKGRVVGIISDRDVRDASPSK
CCCCCCCCCCEEEECCCHHHHHHHHHHHHCCEEECCCCCCCCCEEEEECCCCCCCCCCCC
ATTLDMYEMHYLLAELKAKNIMTANPMTVKPSDTVEQAALIMLDNKIGGLPVVEDSGKLV
CEEHHHHHHHHHHHHHHHCCEEECCCEEECCCCHHHHEEEEEEECCCCCCEEEECCCCEE
GIISDHDVFKALVDITGARLGGLQFAIELPDLPGTARPLFDLLRAHNARLLSVLTVSNED
EEECCHHHHHHHHHHCCCCCCCEEEEEECCCCCCCHHHHHHHHHHCCCEEEEEEEEECCC
GNRHIFIRVRDLKNAAAENTLMEEVAKLGRVLYCIRQNA
CCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHEEECCC
>Mature Secondary Structure 
PVQNWMTTDVVSVTPETSLLKVGKLMKDHHVRRLPVLDDKGRVVGIISDRDVRDASPSK
CCCCCCCCCEEEECCCHHHHHHHHHHHHCCEEECCCCCCCCCEEEEECCCCCCCCCCCC
ATTLDMYEMHYLLAELKAKNIMTANPMTVKPSDTVEQAALIMLDNKIGGLPVVEDSGKLV
CEEHHHHHHHHHHHHHHHCCEEECCCEEECCCCHHHHEEEEEEECCCCCCEEEECCCCEE
GIISDHDVFKALVDITGARLGGLQFAIELPDLPGTARPLFDLLRAHNARLLSVLTVSNED
EEECCHHHHHHHHHHCCCCCCCEEEEEECCCCCCCHHHHHHHHHHCCCEEEEEEEEECCC
GNRHIFIRVRDLKNAAAENTLMEEVAKLGRVLYCIRQNA
CCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7934817; 9387221; 9384377 [H]