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The map label for this gene is citT [C]

Identifier: 220905114

GI number: 220905114

Start: 2232113

End: 2233678

Strand: Direct

Name: citT [C]

Synonym: Ddes_1851

Alternate gene names: 220905114

Gene position: 2232113-2233678 (Clockwise)

Preceding gene: 220905113

Following gene: 220905115

Centisome position: 77.68

GC content: 55.62

Gene sequence:

>1566_bases
GTGTCGCAAGCAGCAAGCACCAAGGCCTTTGACCCCTTGGATATCAGCAATTACTCCCTTGAAAAACTTCCGGAACTCAA
GGGCGGCGTGTGGATGGACCGCATCAAGTTTGCGGGCGTTCCACTGGGCATCATTTCCTTTCTTTATTTCTACCTGCAAT
GGTGCGGTCCCATCGGCGTTTTTGAAGAGCAGGCAAAAGTTCCGCCGGAACATTGCTATGCGGCGCTGGGCATCTTTGTT
TCTTCTCTTGTTCTCTGGCTTTCCGAGGCCATACCCAACTATCTGACTTCGTTTCTGATTATCGTGGCAACCATACTTAC
CGGTGTCATGAAAATGCGCCCGGCCTTTGCCATGCTGGGCGAACCCGTGATGATCCTCAACATCGCAAGTTTCATCATGG
CCAGCGCCCTTGTGGTCACAGGCCTTGCCAAGCGGATATGCCTTTATGTCGTTCTGTCCATGGGCAATAACGTCACGCTT
ATCCTGGCCTGCTTTATCGCGCTGAACCTGCTTCTTGGCGCATTCATCAGCGCCACATCGGCAAAAACAGCCCTGCTTCT
TCCGCTCTTTATGGTCATTTCGGCCATGTACGGCTCTACCGGTGGCGAAAGCCGCAATAATGTGGGCCGCAACATGGTGC
TTCAGAACCTGCTGGCAAACAATGTTTCCGCCTCCGCCTTCATCACTGGCTCGGCCGCCAACCTGCTGGCGGCGCAACTG
CTCGAAAACGCGGGCTACAAGGTCTATTACAGCGACTGGCTCATGGCGCTTCTGCCCCTTTCCATCATCCAGTGCGCCTT
TGCCTGGTACACAGGAACCCGCTGGATATTCCCCATCCGCAAGGAAGACTCCAAACCCAGGCTGGCCGGGGGCCACGAGC
GCCTGCAACAGGAACTTGGCAAGCTTGGCCCGGTTTCGTCAGCGGAAATCCGCGCGGGCATCGTTTTTCTGACCGTGCTG
CTGCTCTGGGGCACTGACCGCTACCACGGCATCCGGGCCGAGGTTACCGCGCTTATGGGGGCCATTGCCGTACTTATGCC
TGCCGTGTGCAAACTGCCGCGCATCGGCGTCATCAAATGGAACGATGCAGACATCCCCTGGCACATGCTCATGTTCAGCT
GGGGGGCCTACGTGCTGGGCGGCCTTATGGACAAAACAGACATTGTGGGCCTGTGGATGCACTATTCGCTGGACACGTGG
GATGCGGCATCCCTGCCCAAGGTGGCAGTATTCGCCCTGCTGGCATCGCTCTTTGCCCTGACGACCCTGGTGAGTGAAAG
CAAGACCGCCCGCACCATCGTGCTTTTTCCCATCATCATCAGCGTGGCAAAAAAATTCGGATGGGACGTCATAGGCTTCT
GCCTGCCCATGGCTTTTCTGATCAACCAGGTTTACGTGCTGTATTTCAACTCCAAACCGGCCAACATCAGCTATCTCACA
AACCAGTATACCAGTTGGGAATCGTTCAAGTTCGGCATGTTCCAGCTTGTGGCCTGCGTACTGATGCTCATTCTGTGGAC
GCAGTACGTCATGCCTCTCATGGGTTTTGACAGCAGGCTCTGGTAG

Upstream 100 bases:

>100_bases
AGCATCCGCCGGTTTCTCACTTCCCGGCGGTGTTTCAGCACCTTCCCAAAGGCCCGTCTCTCCCGAGGCCTTTGGGAAGG
CCGCAGATCAAGGAGGCAAC

Downstream 100 bases:

>100_bases
CGCGCTCCGCGCGCGGCAACCTCCAACGGAGGCACTTATGCGCAAGATATTCGGCTTACTGTTCCTGTTGGGTCTTATGA
CCGCCCTTCCGGCAGACGCG

Product: sodium/sulfate symporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 521; Mature: 520

Protein sequence:

>521_residues
MSQAASTKAFDPLDISNYSLEKLPELKGGVWMDRIKFAGVPLGIISFLYFYLQWCGPIGVFEEQAKVPPEHCYAALGIFV
SSLVLWLSEAIPNYLTSFLIIVATILTGVMKMRPAFAMLGEPVMILNIASFIMASALVVTGLAKRICLYVVLSMGNNVTL
ILACFIALNLLLGAFISATSAKTALLLPLFMVISAMYGSTGGESRNNVGRNMVLQNLLANNVSASAFITGSAANLLAAQL
LENAGYKVYYSDWLMALLPLSIIQCAFAWYTGTRWIFPIRKEDSKPRLAGGHERLQQELGKLGPVSSAEIRAGIVFLTVL
LLWGTDRYHGIRAEVTALMGAIAVLMPAVCKLPRIGVIKWNDADIPWHMLMFSWGAYVLGGLMDKTDIVGLWMHYSLDTW
DAASLPKVAVFALLASLFALTTLVSESKTARTIVLFPIIISVAKKFGWDVIGFCLPMAFLINQVYVLYFNSKPANISYLT
NQYTSWESFKFGMFQLVACVLMLILWTQYVMPLMGFDSRLW

Sequences:

>Translated_521_residues
MSQAASTKAFDPLDISNYSLEKLPELKGGVWMDRIKFAGVPLGIISFLYFYLQWCGPIGVFEEQAKVPPEHCYAALGIFV
SSLVLWLSEAIPNYLTSFLIIVATILTGVMKMRPAFAMLGEPVMILNIASFIMASALVVTGLAKRICLYVVLSMGNNVTL
ILACFIALNLLLGAFISATSAKTALLLPLFMVISAMYGSTGGESRNNVGRNMVLQNLLANNVSASAFITGSAANLLAAQL
LENAGYKVYYSDWLMALLPLSIIQCAFAWYTGTRWIFPIRKEDSKPRLAGGHERLQQELGKLGPVSSAEIRAGIVFLTVL
LLWGTDRYHGIRAEVTALMGAIAVLMPAVCKLPRIGVIKWNDADIPWHMLMFSWGAYVLGGLMDKTDIVGLWMHYSLDTW
DAASLPKVAVFALLASLFALTTLVSESKTARTIVLFPIIISVAKKFGWDVIGFCLPMAFLINQVYVLYFNSKPANISYLT
NQYTSWESFKFGMFQLVACVLMLILWTQYVMPLMGFDSRLW
>Mature_520_residues
SQAASTKAFDPLDISNYSLEKLPELKGGVWMDRIKFAGVPLGIISFLYFYLQWCGPIGVFEEQAKVPPEHCYAALGIFVS
SLVLWLSEAIPNYLTSFLIIVATILTGVMKMRPAFAMLGEPVMILNIASFIMASALVVTGLAKRICLYVVLSMGNNVTLI
LACFIALNLLLGAFISATSAKTALLLPLFMVISAMYGSTGGESRNNVGRNMVLQNLLANNVSASAFITGSAANLLAAQLL
ENAGYKVYYSDWLMALLPLSIIQCAFAWYTGTRWIFPIRKEDSKPRLAGGHERLQQELGKLGPVSSAEIRAGIVFLTVLL
LWGTDRYHGIRAEVTALMGAIAVLMPAVCKLPRIGVIKWNDADIPWHMLMFSWGAYVLGGLMDKTDIVGLWMHYSLDTWD
AASLPKVAVFALLASLFALTTLVSESKTARTIVLFPIIISVAKKFGWDVIGFCLPMAFLINQVYVLYFNSKPANISYLTN
QYTSWESFKFGMFQLVACVLMLILWTQYVMPLMGFDSRLW

Specific function: Responsible For The Uptake Of Citrate In Exchange To The Efflux Of Succinate. Has A Relatively Broad Specificity For C(4)- Dicarboxylates And Tricarboxylates. [C]

COG id: COG0471

COG function: function code P; Di- and tricarboxylate transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the SLC13A transporter (TC 2.A.47) family. SODIT1 subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786829, Length=400, Percent_Identity=22, Blast_Score=66, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001898 [H]

Pfam domain/function: PF00939 Na_sulph_symp [H]

EC number: NA

Molecular weight: Translated: 57495; Mature: 57364

Theoretical pI: Translated: 8.65; Mature: 8.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQAASTKAFDPLDISNYSLEKLPELKGGVWMDRIKFAGVPLGIISFLYFYLQWCGPIGV
CCCCCCCCCCCCCCCCCCCHHHCHHHCCCCHHHHHHHCCCCHHHHHHHHHHHHHHCCCCC
FEEQAKVPPEHCYAALGIFVSSLVLWLSEAIPNYLTSFLIIVATILTGVMKMRPAFAMLG
CHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHC
EPVMILNIASFIMASALVVTGLAKRICLYVVLSMGNNVTLILACFIALNLLLGAFISATS
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHC
AKTALLLPLFMVISAMYGSTGGESRNNVGRNMVLQNLLANNVSASAFITGSAANLLAAQL
HHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEECCHHHHHHHHH
LENAGYKVYYSDWLMALLPLSIIQCAFAWYTGTRWIFPIRKEDSKPRLAGGHERLQQELG
HHHCCCEEEHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCHHHHHHHHH
KLGPVSSAEIRAGIVFLTVLLLWGTDRYHGIRAEVTALMGAIAVLMPAVCKLPRIGVIKW
CCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEE
NDADIPWHMLMFSWGAYVLGGLMDKTDIVGLWMHYSLDTWDAASLPKVAVFALLASLFAL
CCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHEECCCCCCCCCCHHHHHHHHHHHHHHH
TTLVSESKTARTIVLFPIIISVAKKFGWDVIGFCLPMAFLINQVYVLYFNSKPANISYLT
HHHHHCCCCCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCEEEEEECCCCCCCHHHH
NQYTSWESFKFGMFQLVACVLMLILWTQYVMPLMGFDSRLW
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
SQAASTKAFDPLDISNYSLEKLPELKGGVWMDRIKFAGVPLGIISFLYFYLQWCGPIGV
CCCCCCCCCCCCCCCCCCHHHCHHHCCCCHHHHHHHCCCCHHHHHHHHHHHHHHCCCCC
FEEQAKVPPEHCYAALGIFVSSLVLWLSEAIPNYLTSFLIIVATILTGVMKMRPAFAMLG
CHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHC
EPVMILNIASFIMASALVVTGLAKRICLYVVLSMGNNVTLILACFIALNLLLGAFISATS
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHC
AKTALLLPLFMVISAMYGSTGGESRNNVGRNMVLQNLLANNVSASAFITGSAANLLAAQL
HHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEECCHHHHHHHHH
LENAGYKVYYSDWLMALLPLSIIQCAFAWYTGTRWIFPIRKEDSKPRLAGGHERLQQELG
HHHCCCEEEHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCHHHHHHHHH
KLGPVSSAEIRAGIVFLTVLLLWGTDRYHGIRAEVTALMGAIAVLMPAVCKLPRIGVIKW
CCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEE
NDADIPWHMLMFSWGAYVLGGLMDKTDIVGLWMHYSLDTWDAASLPKVAVFALLASLFAL
CCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHEECCCCCCCCCCHHHHHHHHHHHHHHH
TTLVSESKTARTIVLFPIIISVAKKFGWDVIGFCLPMAFLINQVYVLYFNSKPANISYLT
HHHHHCCCCCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCEEEEEECCCCCCCHHHH
NQYTSWESFKFGMFQLVACVLMLILWTQYVMPLMGFDSRLW
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8405966 [H]