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The map label for this gene is gltK [H]

Identifier: 220904829

GI number: 220904829

Start: 1877397

End: 1878074

Strand: Direct

Name: gltK [H]

Synonym: Ddes_1562

Alternate gene names: 220904829

Gene position: 1877397-1878074 (Clockwise)

Preceding gene: 220904828

Following gene: 220904830

Centisome position: 65.34

GC content: 52.36

Gene sequence:

>678_bases
ATGCTTGATTTTGACTGGAGCATCATTGAACAAAGCCTGCCGCTGCTGCAAAAGGGCATTCTGGTAACGCTCAAGATAAC
GATCACGTCCATCATTCTGGGCATGGTGCTCGGCACACTTCTGGCTGTGGCCCGCATTTCCATCTATGCGCCCTTGCGCT
GGCTTGCAGCGGCCTATGTCAACTGCTTCCGCTCCATCCCCCTGGTTATGGTGTTGTTGTGGTTTTATCTTATCGTACCG
CAGTTTTTAACGAAATTTCTTAATCTGTCTCCTCTGACCGATATCCGCCTTGTTTCCGCCATGGTGGCCTTTACCGCTTT
TGAGGCCGCGTATTATTCTGAAATCATCCGGGCGGGCATGAACAGCGTCTCCAGAGGGCAAAACTACGCGGCCCTTGCCC
TCGGCATGACCAAGTCGCAAACGCTCATCTATGTCATTCTGCCGCAGGCTTTCCGCGTCATGACGCCCCTGCTGCTCACA
CAGGGCGTGATTTTGTTTCAGGACACGGCCCTTGTATACATCATAGGCCTTGCGGACTTTTTCCGCACTGCCACCAACAT
AGGCAAAACCACCGGCTATGAAATAGAAATGGTGCTCTTTGCGGGCGCCGGCTACTTTGTTGTCTGCTTCTGCGTTTCCC
TGGCCGTAACCGTGGTAAAAAAGAGACTCAAGCTATGA

Upstream 100 bases:

>100_bases
GTCACGCTGGCGTATGTGTTTTTGAACTTTATCGTCATGCGGGCCATGAAGATGCTTGAAAAGAAAATGCGGCTGCCCTC
CACCGGCATGGGAGGCAAAA

Downstream 100 bases:

>100_bases
ATATACCCACCGAAGAAGCAATGATCGTCCTGAACAACGTATCCAAATGGTACGGTGATTTTAACGTGCTGCGGGACTGC
ACAACCAGCATCCACAAAGG

Product: polar amino acid ABC transporter inner membrane subunit

Products: ADP; phosphate; L-glutamate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 225; Mature: 225

Protein sequence:

>225_residues
MLDFDWSIIEQSLPLLQKGILVTLKITITSIILGMVLGTLLAVARISIYAPLRWLAAAYVNCFRSIPLVMVLLWFYLIVP
QFLTKFLNLSPLTDIRLVSAMVAFTAFEAAYYSEIIRAGMNSVSRGQNYAALALGMTKSQTLIYVILPQAFRVMTPLLLT
QGVILFQDTALVYIIGLADFFRTATNIGKTTGYEIEMVLFAGAGYFVVCFCVSLAVTVVKKRLKL

Sequences:

>Translated_225_residues
MLDFDWSIIEQSLPLLQKGILVTLKITITSIILGMVLGTLLAVARISIYAPLRWLAAAYVNCFRSIPLVMVLLWFYLIVP
QFLTKFLNLSPLTDIRLVSAMVAFTAFEAAYYSEIIRAGMNSVSRGQNYAALALGMTKSQTLIYVILPQAFRVMTPLLLT
QGVILFQDTALVYIIGLADFFRTATNIGKTTGYEIEMVLFAGAGYFVVCFCVSLAVTVVKKRLKL
>Mature_225_residues
MLDFDWSIIEQSLPLLQKGILVTLKITITSIILGMVLGTLLAVARISIYAPLRWLAAAYVNCFRSIPLVMVLLWFYLIVP
QFLTKFLNLSPLTDIRLVSAMVAFTAFEAAYYSEIIRAGMNSVSRGQNYAALALGMTKSQTLIYVILPQAFRVMTPLLLT
QGVILFQDTALVYIIGLADFFRTATNIGKTTGYEIEMVLFAGAGYFVVCFCVSLAVTVVKKRLKL

Specific function: Part of the binding-protein-dependent transport system for aspartate/glutamate; probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0765

COG function: function code E; ABC-type amino acid transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1786873, Length=222, Percent_Identity=63.963963963964, Blast_Score=296, Evalue=6e-82,
Organism=Escherichia coli, GI1788226, Length=203, Percent_Identity=37.4384236453202, Blast_Score=116, Evalue=1e-27,
Organism=Escherichia coli, GI87082239, Length=211, Percent_Identity=34.1232227488152, Blast_Score=101, Evalue=5e-23,
Organism=Escherichia coli, GI1787030, Length=224, Percent_Identity=29.9107142857143, Blast_Score=100, Evalue=7e-23,
Organism=Escherichia coli, GI1786874, Length=237, Percent_Identity=27.0042194092827, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1787087, Length=203, Percent_Identity=26.6009852216749, Blast_Score=78, Evalue=6e-16,
Organism=Escherichia coli, GI48994930, Length=131, Percent_Identity=31.2977099236641, Blast_Score=71, Evalue=6e-14,
Organism=Escherichia coli, GI1788646, Length=207, Percent_Identity=27.0531400966184, Blast_Score=70, Evalue=8e-14,
Organism=Escherichia coli, GI1787086, Length=216, Percent_Identity=26.8518518518519, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1788645, Length=179, Percent_Identity=29.608938547486, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010065
- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 24987; Mature: 24987

Theoretical pI: Translated: 9.67; Mature: 9.67

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLDFDWSIIEQSLPLLQKGILVTLKITITSIILGMVLGTLLAVARISIYAPLRWLAAAYV
CCCCCHHHHHHHHHHHHCCHHEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NCFRSIPLVMVLLWFYLIVPQFLTKFLNLSPLTDIRLVSAMVAFTAFEAAYYSEIIRAGM
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NSVSRGQNYAALALGMTKSQTLIYVILPQAFRVMTPLLLTQGVILFQDTALVYIIGLADF
HHHHCCCCCEEEEEECCCCCEEEEEEHHHHHHHHHHHHHHCCHHEEECHHHHHHHHHHHH
FRTATNIGKTTGYEIEMVLFAGAGYFVVCFCVSLAVTVVKKRLKL
HHHHHHCCCCCCCEEEEEEEECCHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MLDFDWSIIEQSLPLLQKGILVTLKITITSIILGMVLGTLLAVARISIYAPLRWLAAAYV
CCCCCHHHHHHHHHHHHCCHHEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NCFRSIPLVMVLLWFYLIVPQFLTKFLNLSPLTDIRLVSAMVAFTAFEAAYYSEIIRAGM
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NSVSRGQNYAALALGMTKSQTLIYVILPQAFRVMTPLLLTQGVILFQDTALVYIIGLADF
HHHHCCCCCEEEEEECCCCCEEEEEEHHHHHHHHHHHHHHCCHHEEECHHHHHHHHHHHH
FRTATNIGKTTGYEIEMVLFAGAGYFVVCFCVSLAVTVVKKRLKL
HHHHHHCCCCCCCEEEEEEEECCHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; L-glutamate [Periplasm]; H2O [C]

Specific reaction: ATP + L-glutamate [Periplasm] + H2O = ADP + phosphate + L-glutamate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]