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The map label for this gene is nagD [H]

Identifier: 220904790

GI number: 220904790

Start: 1819280

End: 1820059

Strand: Direct

Name: nagD [H]

Synonym: Ddes_1522

Alternate gene names: 220904790

Gene position: 1819280-1820059 (Clockwise)

Preceding gene: 220904786

Following gene: 220904795

Centisome position: 63.31

GC content: 55.51

Gene sequence:

>780_bases
ATGAACTGGTCAAAGAAACGCTGCATGATTCTGGATATGGACGGAACCGTATACCTTGGGCATATCCCCATTGTGGGGGC
TGTAAATTTTATACAGCGCCACTGGCATAGCCTGGATTTTTATTTTCTCAGCAATAATACGTCCAAGTCTCCGGCAAGCT
ATGTGGAAAAACTCCAGGGCATGGGCATACCCGCCAGTATTGAACGCATGCTCTCACCGGTAAGTCCGCTGGTAGACTTT
CTGCGGGCCAACGGTATCCACCGGGCCTACCCTGTGGGAAACAGCGATTTTCAACGCGACCTGCAAAGCCGTATGCCCGA
ACTGCAACTGACGGAAGATGGCGCGCAGGCGGTCATCCTGGCCTACGATACCGAACTGACCTACGAAAAACTGGCCCGGT
CGGCCCTCTTGCTTCAGGATGACAGGGTACTCTTTCTGGCAACGCATCCCGACCTTGTATGCCCCTCCCCCGAAGGCCCT
CTGCCTGATGTGGGCAGTTTCATCAGCCTGTACCAGACCGCCACCGGGCGCAGCCCGCAGCACATTTTCGGCAAGCCGGA
CCCCACTGTGCTGGCTCCGCTTCTGGGGCATTACACGAAAGATGAAATGGTCATGGTGGGCGACCGCCTCAGCACAGATA
AAAAACTGGCCGAAAATGCCGGTATTGACTTCATTCTGGTGCTGAGCGGCGAGGCTGTGCAGGCTGACCTTGAAAAAGAA
ATCATTCAGCCCACCCTGGTGGTGGAAGACCTGGGGTACGCGGAGTCTTTCTGGCGCTGA

Upstream 100 bases:

>100_bases
GAATCTTATTAAAAAGTTGAATCCATCCTGCCTGCTCTTCATTTTTTCAAGAAAGAACGGAATGAAAAACGTGACACGCG
ATACACAAAAAAGGAATGTC

Downstream 100 bases:

>100_bases
CTGTCGCCACCTTCTTTTGCCCTGTCGGTCTCACCGGTCTTTTCCCCATAAGCGGCAGCAATTTTTACTCTGCTTTCGGC
TGTAAAACACTTTTCCGGCC

Product: HAD-superfamily hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 259; Mature: 259

Protein sequence:

>259_residues
MNWSKKRCMILDMDGTVYLGHIPIVGAVNFIQRHWHSLDFYFLSNNTSKSPASYVEKLQGMGIPASIERMLSPVSPLVDF
LRANGIHRAYPVGNSDFQRDLQSRMPELQLTEDGAQAVILAYDTELTYEKLARSALLLQDDRVLFLATHPDLVCPSPEGP
LPDVGSFISLYQTATGRSPQHIFGKPDPTVLAPLLGHYTKDEMVMVGDRLSTDKKLAENAGIDFILVLSGEAVQADLEKE
IIQPTLVVEDLGYAESFWR

Sequences:

>Translated_259_residues
MNWSKKRCMILDMDGTVYLGHIPIVGAVNFIQRHWHSLDFYFLSNNTSKSPASYVEKLQGMGIPASIERMLSPVSPLVDF
LRANGIHRAYPVGNSDFQRDLQSRMPELQLTEDGAQAVILAYDTELTYEKLARSALLLQDDRVLFLATHPDLVCPSPEGP
LPDVGSFISLYQTATGRSPQHIFGKPDPTVLAPLLGHYTKDEMVMVGDRLSTDKKLAENAGIDFILVLSGEAVQADLEKE
IIQPTLVVEDLGYAESFWR
>Mature_259_residues
MNWSKKRCMILDMDGTVYLGHIPIVGAVNFIQRHWHSLDFYFLSNNTSKSPASYVEKLQGMGIPASIERMLSPVSPLVDF
LRANGIHRAYPVGNSDFQRDLQSRMPELQLTEDGAQAVILAYDTELTYEKLARSALLLQDDRVLFLATHPDLVCPSPEGP
LPDVGSFISLYQTATGRSPQHIFGKPDPTVLAPLLGHYTKDEMVMVGDRLSTDKKLAENAGIDFILVLSGEAVQADLEKE
IIQPTLVVEDLGYAESFWR

Specific function: Unknown

COG id: COG0647

COG function: function code G; Predicted sugar phosphatases of the HAD superfamily

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAD-like hydrolase superfamily. NagD family [H]

Homologues:

Organism=Escherichia coli, GI1786890, Length=244, Percent_Identity=24.1803278688525, Blast_Score=69, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17562458, Length=260, Percent_Identity=27.6923076923077, Blast_Score=93, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI71984613, Length=266, Percent_Identity=26.3157894736842, Blast_Score=93, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17558880, Length=260, Percent_Identity=27.6923076923077, Blast_Score=92, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17560956, Length=260, Percent_Identity=27.6923076923077, Blast_Score=92, Evalue=2e-19,
Organism=Saccharomyces cerevisiae, GI6319965, Length=244, Percent_Identity=26.2295081967213, Blast_Score=72, Evalue=8e-14,
Organism=Drosophila melanogaster, GI24666141, Length=256, Percent_Identity=26.5625, Blast_Score=89, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24666137, Length=285, Percent_Identity=26.6666666666667, Blast_Score=83, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24656326, Length=281, Percent_Identity=26.3345195729537, Blast_Score=75, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24641437, Length=224, Percent_Identity=26.3392857142857, Blast_Score=70, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006357
- InterPro:   IPR006354
- InterPro:   IPR023215 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: NA

Molecular weight: Translated: 28849; Mature: 28849

Theoretical pI: Translated: 4.84; Mature: 4.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNWSKKRCMILDMDGTVYLGHIPIVGAVNFIQRHWHSLDFYFLSNNTSKSPASYVEKLQG
CCCCCCEEEEEECCCCEEEECCCHHHHHHHHHHHHCCEEEEEEECCCCCCHHHHHHHHHC
MGIPASIERMLSPVSPLVDFLRANGIHRAYPVGNSDFQRDLQSRMPELQLTEDGAQAVIL
CCCCHHHHHHHHHHHHHHHHHHHCCCCEECCCCCHHHHHHHHHHCCCEEEECCCCCEEEE
AYDTELTYEKLARSALLLQDDRVLFLATHPDLVCPSPEGPLPDVGSFISLYQTATGRSPQ
EECCCHHHHHHHHHHHEEECCCEEEEECCCCEECCCCCCCCCCHHHHHHHHHHHCCCCCC
HIFGKPDPTVLAPLLGHYTKDEMVMVGDRLSTDKKLAENAGIDFILVLSGEAVQADLEKE
CCCCCCCHHHHHHHHCCCCCCCEEEECCCCCCHHHHHHHCCCCEEEEECCCHHHHHHHHH
IIQPTLVVEDLGYAESFWR
HHCHHHEEHHCCCHHHHCC
>Mature Secondary Structure
MNWSKKRCMILDMDGTVYLGHIPIVGAVNFIQRHWHSLDFYFLSNNTSKSPASYVEKLQG
CCCCCCEEEEEECCCCEEEECCCHHHHHHHHHHHHCCEEEEEEECCCCCCHHHHHHHHHC
MGIPASIERMLSPVSPLVDFLRANGIHRAYPVGNSDFQRDLQSRMPELQLTEDGAQAVIL
CCCCHHHHHHHHHHHHHHHHHHHCCCCEECCCCCHHHHHHHHHHCCCEEEECCCCCEEEE
AYDTELTYEKLARSALLLQDDRVLFLATHPDLVCPSPEGPLPDVGSFISLYQTATGRSPQ
EECCCHHHHHHHHHHHEEECCCEEEEECCCCEECCCCCCCCCCHHHHHHHHHHHCCCCCC
HIFGKPDPTVLAPLLGHYTKDEMVMVGDRLSTDKKLAENAGIDFILVLSGEAVQADLEKE
CCCCCCCHHHHHHHHCCCCCCCEEEECCCCCCHHHHHHHCCCCEEEEECCCHHHHHHHHH
IIQPTLVVEDLGYAESFWR
HHCHHHEEHHCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA