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The map label for this gene is murG [H]

Identifier: 220904384

GI number: 220904384

Start: 1306925

End: 1308001

Strand: Direct

Name: murG [H]

Synonym: Ddes_1113

Alternate gene names: 220904384

Gene position: 1306925-1308001 (Clockwise)

Preceding gene: 220904383

Following gene: 220904385

Centisome position: 45.48

GC content: 60.91

Gene sequence:

>1077_bases
ATGGACATCAACATCCTCCTGACCACGGGCGGCACAGGCGGGCACATTTTTCCTGCTCTGGCCGTTGCCGAGGAGATTCG
GCGGAGATACCCTCAGGCCAGGCTGCTTTTTGTAGGTTCACTCTACGGGCCTGAAGCACGTTTGGCCCGCGTGGCAAATA
TTCCCTTTGAGGGCTTGCCTGTGCGCGGTTTTTTGGGGCGTGGCCTGAAATCTGTGGAGGCCGGTATACGTATGGCCTGG
GGCGTAGGCAGAGCCGTGGGCATTGTCCGGCGTTTCAGGCCTGACGTGGTGGCTGGTTTCGGCAGTTATGCCGCCTTTGC
GCCCATGCTGGCTGGACGTATGCTGGGCGTGCCGATCATGCTGCATGAACAGAACGCCATAGCGGGGGCCAGCAACCGTG
TGTTGGCGCGTCTGGCGCAGCGTATCTGCCTTTCTTTGCCGGACACCAGGGGCTTTGATCCCGCCAGGTGCGTTCTGACA
GGCAACCCCGTGCGCGCCGGAGTGAGCGAGGCCGGGCGGTTGCCGCGTGCACGCGGGGCCAGACGGCTTCTGGTGATGGG
GGGGTCGCAGGGAGCGCATGCCCTGAACATGTTTATCGTGGAGCACCTTTCTGCCTTCAAGGCTGCCGGTGTGGATATCC
GCCATCAGACAGGCGTTGCGGATGAACAGAACGTGCGCGACGCCTATGTTGCCGCAGGGTATGAAGCTTCTACGGTTACG
GCGTTTATTGATGATATGGCTGCGGCCTATGCCTGGGCTGACGTGGCCCTGTGCCGTTCTGGAGCTACTACTGTGGCCGA
ATTGTGCGCTGCCGGGCTGCCTTCGGTTCTGGTTCCTTTTCCTTATGCGGTTCATGACCACCAAACCCGCAATGCCGAAA
TTCTGGCCCAAGGTGGAGCGGCCATTCTTGTGCCCGAACCGCGCATGATTGAAGAAAACCTGGCTCAGACGCTTATCGAT
CTGCTCAATGACGGCAGCGAGCGCACACGTATGTCGGCCGCAGCTCTTGCCGCAGCCCGGCCTGATGCCGCCAGCCGCGT
GGTTTCTGTTTTGGAAGAGATAGCCCGTCTGCGCTGA

Upstream 100 bases:

>100_bases
AGGGTGTACCCATGCCCCTTATGAGCTATGGGGGCAGTAACCTGCTTGCGACCATGCTTTGCGTGGGGCTGCTTATGAAC
TTTTCACGAACGGCGGACAC

Downstream 100 bases:

>100_bases
ACGCGGTTGCGGGATATTTGGGTGGCAGACTGCCGCCTGTGGATTATCTAGACATTCTTTAAAGGTAACGCATGAACAGC
AAGATCCGGCACATCCACAT

Product: undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase

Products: NA

Alternate protein names: Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase [H]

Number of amino acids: Translated: 358; Mature: 358

Protein sequence:

>358_residues
MDINILLTTGGTGGHIFPALAVAEEIRRRYPQARLLFVGSLYGPEARLARVANIPFEGLPVRGFLGRGLKSVEAGIRMAW
GVGRAVGIVRRFRPDVVAGFGSYAAFAPMLAGRMLGVPIMLHEQNAIAGASNRVLARLAQRICLSLPDTRGFDPARCVLT
GNPVRAGVSEAGRLPRARGARRLLVMGGSQGAHALNMFIVEHLSAFKAAGVDIRHQTGVADEQNVRDAYVAAGYEASTVT
AFIDDMAAAYAWADVALCRSGATTVAELCAAGLPSVLVPFPYAVHDHQTRNAEILAQGGAAILVPEPRMIEENLAQTLID
LLNDGSERTRMSAAALAAARPDAASRVVSVLEEIARLR

Sequences:

>Translated_358_residues
MDINILLTTGGTGGHIFPALAVAEEIRRRYPQARLLFVGSLYGPEARLARVANIPFEGLPVRGFLGRGLKSVEAGIRMAW
GVGRAVGIVRRFRPDVVAGFGSYAAFAPMLAGRMLGVPIMLHEQNAIAGASNRVLARLAQRICLSLPDTRGFDPARCVLT
GNPVRAGVSEAGRLPRARGARRLLVMGGSQGAHALNMFIVEHLSAFKAAGVDIRHQTGVADEQNVRDAYVAAGYEASTVT
AFIDDMAAAYAWADVALCRSGATTVAELCAAGLPSVLVPFPYAVHDHQTRNAEILAQGGAAILVPEPRMIEENLAQTLID
LLNDGSERTRMSAAALAAARPDAASRVVSVLEEIARLR
>Mature_358_residues
MDINILLTTGGTGGHIFPALAVAEEIRRRYPQARLLFVGSLYGPEARLARVANIPFEGLPVRGFLGRGLKSVEAGIRMAW
GVGRAVGIVRRFRPDVVAGFGSYAAFAPMLAGRMLGVPIMLHEQNAIAGASNRVLARLAQRICLSLPDTRGFDPARCVLT
GNPVRAGVSEAGRLPRARGARRLLVMGGSQGAHALNMFIVEHLSAFKAAGVDIRHQTGVADEQNVRDAYVAAGYEASTVT
AFIDDMAAAYAWADVALCRSGATTVAELCAAGLPSVLVPFPYAVHDHQTRNAEILAQGGAAILVPEPRMIEENLAQTLID
LLNDGSERTRMSAAALAAARPDAASRVVSVLEEIARLR

Specific function: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) [H]

COG id: COG0707

COG function: function code M; UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 28 family. MurG subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786278, Length=362, Percent_Identity=41.1602209944751, Blast_Score=216, Evalue=1e-57,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006009
- InterPro:   IPR004276
- InterPro:   IPR007235 [H]

Pfam domain/function: PF04101 Glyco_tran_28_C; PF03033 Glyco_transf_28 [H]

EC number: =2.4.1.227 [H]

Molecular weight: Translated: 37977; Mature: 37977

Theoretical pI: Translated: 9.49; Mature: 9.49

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDINILLTTGGTGGHIFPALAVAEEIRRRYPQARLLFVGSLYGPEARLARVANIPFEGLP
CCEEEEEEECCCCCHHHHHHHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHHCCCCCCCC
VRGFLGRGLKSVEAGIRMAWGVGRAVGIVRRFRPDVVAGFGSYAAFAPMLAGRMLGVPIM
CHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCHHHHHHHHHHHHHHCCEEE
LHEQNAIAGASNRVLARLAQRICLSLPDTRGFDPARCVLTGNPVRAGVSEAGRLPRARGA
EECCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCHHCCHHHHCCCCCCCCC
RRLLVMGGSQGAHALNMFIVEHLSAFKAAGVDIRHQTGVADEQNVRDAYVAAGYEASTVT
CEEEEEECCCCHHHHHHHHHHHHHHHHHCCCCEECCCCCCCCCCCCHHHHCCCCCHHHHH
AFIDDMAAAYAWADVALCRSGATTVAELCAAGLPSVLVPFPYAVHDHQTRNAEILAQGGA
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCHHHHCCCCCCCCCCCCCCEEEECCCC
AILVPEPRMIEENLAQTLIDLLNDGSERTRMSAAALAAARPDAASRVVSVLEEIARLR
EEEECCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MDINILLTTGGTGGHIFPALAVAEEIRRRYPQARLLFVGSLYGPEARLARVANIPFEGLP
CCEEEEEEECCCCCHHHHHHHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHHCCCCCCCC
VRGFLGRGLKSVEAGIRMAWGVGRAVGIVRRFRPDVVAGFGSYAAFAPMLAGRMLGVPIM
CHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCHHHHHHHHHHHHHHCCEEE
LHEQNAIAGASNRVLARLAQRICLSLPDTRGFDPARCVLTGNPVRAGVSEAGRLPRARGA
EECCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCHHCCHHHHCCCCCCCCC
RRLLVMGGSQGAHALNMFIVEHLSAFKAAGVDIRHQTGVADEQNVRDAYVAAGYEASTVT
CEEEEEECCCCHHHHHHHHHHHHHHHHHCCCCEECCCCCCCCCCCCHHHHCCCCCHHHHH
AFIDDMAAAYAWADVALCRSGATTVAELCAAGLPSVLVPFPYAVHDHQTRNAEILAQGGA
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCHHHHCCCCCCCCCCCCCCEEEECCCC
AILVPEPRMIEENLAQTLIDLLNDGSERTRMSAAALAAARPDAASRVVSVLEEIARLR
EEEECCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA