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The map label for this gene is dsbD [H]

Identifier: 220904294

GI number: 220904294

Start: 1194518

End: 1196533

Strand: Direct

Name: dsbD [H]

Synonym: Ddes_1021

Alternate gene names: 220904294

Gene position: 1194518-1196533 (Clockwise)

Preceding gene: 220904291

Following gene: 220904295

Centisome position: 41.57

GC content: 57.49

Gene sequence:

>2016_bases
GTGAAATTAAATGATTTTTATTTAATAAAGGTTTTCAGGGCATACAGGTTTTCTACAGCCCTGTGGCTGATACCCCTGTG
TATCAGCTTGTTTCTTTTTGTCTTTTTTTCCCGGGCAGAGGCTGAAAGCCTCTCGGGTCGCTTTGAAACCGCAGCGGAAG
GCGGCAATCTCATAGGAGCCTTGCACCTGACCCTGCCGCAGGGTTTTCATGCTTATGCGCACGACCCCGGCGATGCGGGC
CGCCCTACAACACTGCGCTTCAGCGTTGACGGCGGCGCGCCGCAGGCCGTGTGGTATCCTGAAGGCGCTGTACAGCGGGA
TTTTTATGATCCTTCGGCCACAATTTTTGTTTATGAGAGCGAGGTAACGCTCTATGTGCTTTTGCCCGCAGCCGATGCAG
GCAAGACCTATACTGCTGATGTGAGCATGCTGCTCTGCTCGACACGCAACTGTATGCCCGTCAACCAGCAGTTTCAGGGC
GTGGTTCCCCGGGCAGACCTGCCCCTTGCCGATGTGCCCTGGGCGGCACGGTGGCGCGGGCTGAAAAAACAGCCACCCAG
ATTTTTTGAAGGTGGGACCGCACAGGCGCTGCCCGCTTTTGGCACGGGCTCTTCCTTGGCAGCCGGTTCAGATCAGGTTC
CGGCCGAAGGGCAGGGCAGCGTGTCCTCCGACGGAAAGTCTGAAGGCATAGCCCGCTGGCTGGCAGCCCAGAACGGTGAG
GCTGCCCCTGCGAGTGATAAGAAACTTGAAGAAGAAAAAGGGCAAAAAGCCCTGCCGCCGCCCGATGGCTTTGTAAGCCT
GACGCCTCGCTATATGGATGAATCAATGGAGATATCAGGACTTGGCAAAGCTCTGCTGTTCGGCATTCTGGCCGGCCTGC
TGCTCAATGCCATGCCCTGTGTGCTGCCCGTGCTTACTTTTAAGGTCAGCGGCCTTCTCATGGTAGGCGGCTACGACAAG
GAAGGGTTGAAAAATTTCAGACGGCATAACATCTGCTTTGCCGCGGGGGTCATGACGCTGTTCAGCGCCCTCGCCCTGGT
GCTCGGGCTTGCGGATCTGATGTGGGGGCAATTGTACCAGAGTCAGCCTGTTCTGCTTGTCATGCTGCTGCTGGTATTTC
TCATGGGCCTTTCCATGCTGGGTGTTTTTACCCTGCCCGTCATAGACCTGAAAACCGGCACAAATACCAAGAATCCCTGC
CTTCAGGCCTACTTTACGGGACTTGTCTCCACCTTTCTGGCTACGCCATGCAGCGGACCTCTTTTGGGGGGCGTGCTTGG
CTGGGCCTTCACCCAGCCCCTCATGGTGGTTGTGGTGGTTTTCTGGGCAGTTGGCCTAGGCATGGCCCTGCCGTATGTCC
TGTTCAGCATCTGGCCTGTGCTGGCGCGTATTTTGCCCAAACCCGGCGCGTGGATGCATGTTTTTGAAAGGGTTGTGGGC
TTTTTTCTGCTGGGTACGGCCCTGTATCTGCTCTCCATCCTGCCTGTGGAAAAGCACATGCAGGTGCTGAGCGTCCTGCT
GGTTGTGGCCCTGTGTGCATGGCTGTGGGGCCAGTTTTGCGGCATATCGGCACCGCCTCTGCGCCGCCGTGTTGTAGGCC
TTGTTTCTCTTGGCCTGCTGCTGGCCTCCTTTGTCTGGGTGCTGCGTCCCGTGGCGCCTTTGCCGCAGTGGCGTGATTTT
ACTCCGCAAACATTTGAAGCAACCCTGGGGCATAAGCCCATGCTGCTGGAATTTACTGCCGACTGGTGCCCGAACTGCAA
GTTTATGGAGGCTACCGTACTGACGGATGAACGCCTGCGCCGCTTGCAGGCCCGCTACGGCATGGAGCTTGTGCGGGTGG
ATCTGACCAATGCCAATGCCTATGCTGTACGGCTTCTGGAGGCCCTGGGCAGCAAAAGCATCCCGCTTACGGCGCTGTTT
CCCGCAGGAAGCGAGGCCACTGCCCCCCTGGTGCTCCGCGATGTGTACGGAGGTGAAACGCTGGAACGCGCTTTGGGTGA
AGCATTCGGGAAATAA

Upstream 100 bases:

>100_bases
ATTGAGCTAATGACCCGCATTGCGTGAAAAGGGGTTTACGCTTATGGGTGCCAACTGTCAAGCAATTTTGAAAAAAAAAT
AGAAAGAAAGAGTTAATATT

Downstream 100 bases:

>100_bases
TGGATTTTTTTCCGGTAGGCCTATGGTGCTTTACCAATCAGCCGATAAGGCATAGTATGTAAAAAGGCGTGGGCCGGCGG
TATTCTCTTCGGCCTTTGTA

Product: cytochrome c biogenesis protein transmembrane subunit

Products: NA

Alternate protein names: Protein-disulfide reductase; Disulfide reductase [H]

Number of amino acids: Translated: 671; Mature: 671

Protein sequence:

>671_residues
MKLNDFYLIKVFRAYRFSTALWLIPLCISLFLFVFFSRAEAESLSGRFETAAEGGNLIGALHLTLPQGFHAYAHDPGDAG
RPTTLRFSVDGGAPQAVWYPEGAVQRDFYDPSATIFVYESEVTLYVLLPAADAGKTYTADVSMLLCSTRNCMPVNQQFQG
VVPRADLPLADVPWAARWRGLKKQPPRFFEGGTAQALPAFGTGSSLAAGSDQVPAEGQGSVSSDGKSEGIARWLAAQNGE
AAPASDKKLEEEKGQKALPPPDGFVSLTPRYMDESMEISGLGKALLFGILAGLLLNAMPCVLPVLTFKVSGLLMVGGYDK
EGLKNFRRHNICFAAGVMTLFSALALVLGLADLMWGQLYQSQPVLLVMLLLVFLMGLSMLGVFTLPVIDLKTGTNTKNPC
LQAYFTGLVSTFLATPCSGPLLGGVLGWAFTQPLMVVVVVFWAVGLGMALPYVLFSIWPVLARILPKPGAWMHVFERVVG
FFLLGTALYLLSILPVEKHMQVLSVLLVVALCAWLWGQFCGISAPPLRRRVVGLVSLGLLLASFVWVLRPVAPLPQWRDF
TPQTFEATLGHKPMLLEFTADWCPNCKFMEATVLTDERLRRLQARYGMELVRVDLTNANAYAVRLLEALGSKSIPLTALF
PAGSEATAPLVLRDVYGGETLERALGEAFGK

Sequences:

>Translated_671_residues
MKLNDFYLIKVFRAYRFSTALWLIPLCISLFLFVFFSRAEAESLSGRFETAAEGGNLIGALHLTLPQGFHAYAHDPGDAG
RPTTLRFSVDGGAPQAVWYPEGAVQRDFYDPSATIFVYESEVTLYVLLPAADAGKTYTADVSMLLCSTRNCMPVNQQFQG
VVPRADLPLADVPWAARWRGLKKQPPRFFEGGTAQALPAFGTGSSLAAGSDQVPAEGQGSVSSDGKSEGIARWLAAQNGE
AAPASDKKLEEEKGQKALPPPDGFVSLTPRYMDESMEISGLGKALLFGILAGLLLNAMPCVLPVLTFKVSGLLMVGGYDK
EGLKNFRRHNICFAAGVMTLFSALALVLGLADLMWGQLYQSQPVLLVMLLLVFLMGLSMLGVFTLPVIDLKTGTNTKNPC
LQAYFTGLVSTFLATPCSGPLLGGVLGWAFTQPLMVVVVVFWAVGLGMALPYVLFSIWPVLARILPKPGAWMHVFERVVG
FFLLGTALYLLSILPVEKHMQVLSVLLVVALCAWLWGQFCGISAPPLRRRVVGLVSLGLLLASFVWVLRPVAPLPQWRDF
TPQTFEATLGHKPMLLEFTADWCPNCKFMEATVLTDERLRRLQARYGMELVRVDLTNANAYAVRLLEALGSKSIPLTALF
PAGSEATAPLVLRDVYGGETLERALGEAFGK
>Mature_671_residues
MKLNDFYLIKVFRAYRFSTALWLIPLCISLFLFVFFSRAEAESLSGRFETAAEGGNLIGALHLTLPQGFHAYAHDPGDAG
RPTTLRFSVDGGAPQAVWYPEGAVQRDFYDPSATIFVYESEVTLYVLLPAADAGKTYTADVSMLLCSTRNCMPVNQQFQG
VVPRADLPLADVPWAARWRGLKKQPPRFFEGGTAQALPAFGTGSSLAAGSDQVPAEGQGSVSSDGKSEGIARWLAAQNGE
AAPASDKKLEEEKGQKALPPPDGFVSLTPRYMDESMEISGLGKALLFGILAGLLLNAMPCVLPVLTFKVSGLLMVGGYDK
EGLKNFRRHNICFAAGVMTLFSALALVLGLADLMWGQLYQSQPVLLVMLLLVFLMGLSMLGVFTLPVIDLKTGTNTKNPC
LQAYFTGLVSTFLATPCSGPLLGGVLGWAFTQPLMVVVVVFWAVGLGMALPYVLFSIWPVLARILPKPGAWMHVFERVVG
FFLLGTALYLLSILPVEKHMQVLSVLLVVALCAWLWGQFCGISAPPLRRRVVGLVSLGLLLASFVWVLRPVAPLPQWRDF
TPQTFEATLGHKPMLLEFTADWCPNCKFMEATVLTDERLRRLQARYGMELVRVDLTNANAYAVRLLEALGSKSIPLTALF
PAGSEATAPLVLRDVYGGETLERALGEAFGK

Specific function: Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a

COG id: COG4232

COG function: function code OC; Thiol:disulfide interchange protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Escherichia coli, GI1790578, Length=393, Percent_Identity=25.9541984732824, Blast_Score=84, Evalue=4e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003834
- InterPro:   IPR022910
- InterPro:   IPR005746
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR017937
- InterPro:   IPR013766
- InterPro:   IPR012335 [H]

Pfam domain/function: PF02683 DsbD; PF00085 Thioredoxin [H]

EC number: =1.8.1.8 [H]

Molecular weight: Translated: 72930; Mature: 72930

Theoretical pI: Translated: 7.63; Mature: 7.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLNDFYLIKVFRAYRFSTALWLIPLCISLFLFVFFSRAEAESLSGRFETAAEGGNLIGA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCEEEE
LHLTLPQGFHAYAHDPGDAGRPTTLRFSVDGGAPQAVWYPEGAVQRDFYDPSATIFVYES
EEEECCCCCCCCCCCCCCCCCCEEEEEEECCCCCCEEECCCCCCCCCCCCCCCEEEEEEC
EVTLYVLLPAADAGKTYTADVSMLLCSTRNCMPVNQQFQGVVPRADLPLADVPWAARWRG
CEEEEEEEECCCCCCEEEHHHHHHHHCCCCCCCCCHHHCCCCCCCCCCCCCCCHHHHHCC
LKKQPPRFFEGGTAQALPAFGTGSSLAAGSDQVPAEGQGSVSSDGKSEGIARWLAAQNGE
CCCCCCCHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCC
AAPASDKKLEEEKGQKALPPPDGFVSLTPRYMDESMEISGLGKALLFGILAGLLLNAMPC
CCCCCCHHHHHHCCCCCCCCCCCCEECCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHH
VLPVLTFKVSGLLMVGGYDKEGLKNFRRHNICFAAGVMTLFSALALVLGLADLMWGQLYQ
HHHHHHHHHCCEEEECCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
SQPVLLVMLLLVFLMGLSMLGVFTLPVIDLKTGTNTKNPCLQAYFTGLVSTFLATPCSGP
CCCHHHHHHHHHHHHHHHHHHHHHHCEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCH
LLGGVLGWAFTQPLMVVVVVFWAVGLGMALPYVLFSIWPVLARILPKPGAWMHVFERVVG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
FFLLGTALYLLSILPVEKHMQVLSVLLVVALCAWLWGQFCGISAPPLRRRVVGLVSLGLL
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
LASFVWVLRPVAPLPQWRDFTPQTFEATLGHKPMLLEFTADWCPNCKFMEATVLTDERLR
HHHHHHHHHCCCCCCCCCCCCCCHHHHHCCCCCEEEEECCCCCCCCCEEEEECCCHHHHH
RLQARYGMELVRVDLTNANAYAVRLLEALGSKSIPLTALFPAGSEATAPLVLRDVYGGET
HHHHHHCCEEEEEEECCCCHHHHHHHHHHCCCCCCEEEEECCCCCCCCCEEEHHHCCCHH
LERALGEAFGK
HHHHHHHHHCC
>Mature Secondary Structure
MKLNDFYLIKVFRAYRFSTALWLIPLCISLFLFVFFSRAEAESLSGRFETAAEGGNLIGA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCEEEE
LHLTLPQGFHAYAHDPGDAGRPTTLRFSVDGGAPQAVWYPEGAVQRDFYDPSATIFVYES
EEEECCCCCCCCCCCCCCCCCCEEEEEEECCCCCCEEECCCCCCCCCCCCCCCEEEEEEC
EVTLYVLLPAADAGKTYTADVSMLLCSTRNCMPVNQQFQGVVPRADLPLADVPWAARWRG
CEEEEEEEECCCCCCEEEHHHHHHHHCCCCCCCCCHHHCCCCCCCCCCCCCCCHHHHHCC
LKKQPPRFFEGGTAQALPAFGTGSSLAAGSDQVPAEGQGSVSSDGKSEGIARWLAAQNGE
CCCCCCCHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCC
AAPASDKKLEEEKGQKALPPPDGFVSLTPRYMDESMEISGLGKALLFGILAGLLLNAMPC
CCCCCCHHHHHHCCCCCCCCCCCCEECCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHH
VLPVLTFKVSGLLMVGGYDKEGLKNFRRHNICFAAGVMTLFSALALVLGLADLMWGQLYQ
HHHHHHHHHCCEEEECCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
SQPVLLVMLLLVFLMGLSMLGVFTLPVIDLKTGTNTKNPCLQAYFTGLVSTFLATPCSGP
CCCHHHHHHHHHHHHHHHHHHHHHHCEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCH
LLGGVLGWAFTQPLMVVVVVFWAVGLGMALPYVLFSIWPVLARILPKPGAWMHVFERVVG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
FFLLGTALYLLSILPVEKHMQVLSVLLVVALCAWLWGQFCGISAPPLRRRVVGLVSLGLL
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
LASFVWVLRPVAPLPQWRDFTPQTFEATLGHKPMLLEFTADWCPNCKFMEATVLTDERLR
HHHHHHHHHCCCCCCCCCCCCCCHHHHHCCCCCEEEEECCCCCCCCCEEEEECCCHHHHH
RLQARYGMELVRVDLTNANAYAVRLLEALGSKSIPLTALFPAGSEATAPLVLRDVYGGET
HHHHHHCCEEEEEEECCCCHHHHHHHHHHCCCCCCEEEEECCCCCCCCCEEEHHHCCCHH
LERALGEAFGK
HHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA