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The map label for this gene is znuC [H]

Identifier: 220904282

GI number: 220904282

Start: 1177425

End: 1178351

Strand: Direct

Name: znuC [H]

Synonym: Ddes_1009

Alternate gene names: 220904282

Gene position: 1177425-1178351 (Clockwise)

Preceding gene: 220904281

Following gene: 220904283

Centisome position: 40.98

GC content: 61.27

Gene sequence:

>927_bases
TTGAGCAGCGCTGACACGGCCGCCCCTGATCTTGTTTTTGACCATGTGCATGTGTGTCAGGGTGGGCGTTCCATTCTGGA
TGATGTGTACGCCACAGTACCGGCCGGAAGCAGCACGGTGATTGTCGGACCCAACGGAGCAGGTAAAACCACGCTTCTGC
TGTGCCTTATCGGTGAAATGCCCTATACGGGGCGTATTATTGCGGCAGGCCGGGCAAGCCTGCCGCGTACTGCGTACGTG
CCGCAACATCTGTATCTGGATGCCAGCCTGCCCTTGCGGGTGGGTGAATTTTTGGCACTCAACCGCCAACGCCGCCCGCT
GTGGCTCGGCCTCTACGGTCCAGAACGGGCAAAGGCGCGGGACCTTCTGCGTATGGTGCGGGCAGAACAGCTTGAAGAAC
GCCGTATGAGCGACCTTTCCGGCGGCGAAACGCGTCGGGTACTGCTGGCCGCCGCTCTGGACAGGGCGCCGCGTCTGCTG
GTGCTGGACGAACCTGCCGCCGGGGTGGATGTGCAGGGGGAGCGCCTGTTCTGGGAGGTGCTTGACGAAGCCCGCAAACA
GCAGGGCTTCACCCAACTGATGGTCAGTCATAATCTGTCACTGGCAGCCCACTATGCCACGCATATCATCTGCCTAAACA
AAAAGGTCTGCGCAGAGGGCGCCCCCCATGAAGCCCTTGGAGCCTCTACCTTGATGCAGCTTTTTGGCGTGCCTATCCAC
CTTTATCCCGACCAGTGCGATCCGGCTGATCCCTCCTGCCCGCAATGTGGGGCCGTATGCGCCCCGGAACGTCTGCTGCC
GGACTATGCCAGCGTGAAGCGTCGGTCCGAAGCGCACCGGCCGCAGGATGCCCCGGCAGTGCATGCAGCACAGGGTGCTG
TGAAAAAGGGTAAAACCCATGCCGCAAAGGAGAGTGACCATGCCTGA

Upstream 100 bases:

>100_bases
GCCGTTTCGCTCGACTCTCTGGCTTCCGGGCCGGCTTCTCCACCACTGGACTACTATGAGAAAACCATGAGCAATAATCT
TGATATCCTTGAGAAGCACC

Downstream 100 bases:

>100_bases
ACTTGCATGGGCATATGATCTTTTGGGCCGTTTGCCGCTGGACTGCCTGCAGTTACGCTTTATGCAGCAGGCCCTGTTCG
GCCTGCTGTTGTTGGCGCCT

Product: ABC transporter-like protein

Products: Zn (II) [Cytoplasm]; ADP; phosphate [C]

Alternate protein names: NA

Number of amino acids: Translated: 308; Mature: 307

Protein sequence:

>308_residues
MSSADTAAPDLVFDHVHVCQGGRSILDDVYATVPAGSSTVIVGPNGAGKTTLLLCLIGEMPYTGRIIAAGRASLPRTAYV
PQHLYLDASLPLRVGEFLALNRQRRPLWLGLYGPERAKARDLLRMVRAEQLEERRMSDLSGGETRRVLLAAALDRAPRLL
VLDEPAAGVDVQGERLFWEVLDEARKQQGFTQLMVSHNLSLAAHYATHIICLNKKVCAEGAPHEALGASTLMQLFGVPIH
LYPDQCDPADPSCPQCGAVCAPERLLPDYASVKRRSEAHRPQDAPAVHAAQGAVKKGKTHAAKESDHA

Sequences:

>Translated_308_residues
MSSADTAAPDLVFDHVHVCQGGRSILDDVYATVPAGSSTVIVGPNGAGKTTLLLCLIGEMPYTGRIIAAGRASLPRTAYV
PQHLYLDASLPLRVGEFLALNRQRRPLWLGLYGPERAKARDLLRMVRAEQLEERRMSDLSGGETRRVLLAAALDRAPRLL
VLDEPAAGVDVQGERLFWEVLDEARKQQGFTQLMVSHNLSLAAHYATHIICLNKKVCAEGAPHEALGASTLMQLFGVPIH
LYPDQCDPADPSCPQCGAVCAPERLLPDYASVKRRSEAHRPQDAPAVHAAQGAVKKGKTHAAKESDHA
>Mature_307_residues
SSADTAAPDLVFDHVHVCQGGRSILDDVYATVPAGSSTVIVGPNGAGKTTLLLCLIGEMPYTGRIIAAGRASLPRTAYVP
QHLYLDASLPLRVGEFLALNRQRRPLWLGLYGPERAKARDLLRMVRAEQLEERRMSDLSGGETRRVLLAAALDRAPRLLV
LDEPAAGVDVQGERLFWEVLDEARKQQGFTQLMVSHNLSLAAHYATHIICLNKKVCAEGAPHEALGASTLMQLFGVPIHL
YPDQCDPADPSCPQCGAVCAPERLLPDYASVKRRSEAHRPQDAPAVHAAQGAVKKGKTHAAKESDHA

Specific function: Part of the ABC transporter complex ZnuABC involved in zinc import. Responsible for energy coupling to the transport system [H]

COG id: COG1121

COG function: function code P; ABC-type Mn/Zn transport systems, ATPase component

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Homo sapiens, GI190343023, Length=204, Percent_Identity=29.4117647058824, Blast_Score=69, Evalue=6e-12,
Organism=Homo sapiens, GI27881501, Length=223, Percent_Identity=26.9058295964126, Blast_Score=65, Evalue=6e-11,
Organism=Homo sapiens, GI30795238, Length=223, Percent_Identity=26.9058295964126, Blast_Score=65, Evalue=6e-11,
Organism=Escherichia coli, GI1788165, Length=225, Percent_Identity=39.5555555555556, Blast_Score=142, Evalue=3e-35,
Organism=Escherichia coli, GI1790739, Length=245, Percent_Identity=28.9795918367347, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1786345, Length=233, Percent_Identity=29.6137339055794, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI87081709, Length=236, Percent_Identity=30.0847457627119, Blast_Score=93, Evalue=3e-20,
Organism=Escherichia coli, GI1786803, Length=233, Percent_Identity=27.8969957081545, Blast_Score=89, Evalue=5e-19,
Organism=Escherichia coli, GI87081834, Length=204, Percent_Identity=32.3529411764706, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1788761, Length=204, Percent_Identity=28.4313725490196, Blast_Score=82, Evalue=5e-17,
Organism=Escherichia coli, GI1786563, Length=213, Percent_Identity=32.3943661971831, Blast_Score=82, Evalue=6e-17,
Organism=Escherichia coli, GI1787029, Length=226, Percent_Identity=27.4336283185841, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1786319, Length=232, Percent_Identity=29.3103448275862, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1787370, Length=215, Percent_Identity=27.4418604651163, Blast_Score=71, Evalue=9e-14,
Organism=Escherichia coli, GI48994943, Length=219, Percent_Identity=26.9406392694064, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1789593, Length=221, Percent_Identity=31.2217194570136, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1789672, Length=233, Percent_Identity=26.6094420600858, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1787758, Length=202, Percent_Identity=28.7128712871287, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1786398, Length=233, Percent_Identity=27.0386266094421, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1786253, Length=213, Percent_Identity=29.5774647887324, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI1788225, Length=223, Percent_Identity=30.0448430493274, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1789864, Length=242, Percent_Identity=27.2727272727273, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1786975, Length=227, Percent_Identity=29.5154185022026, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1790544, Length=216, Percent_Identity=25.462962962963, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1789891, Length=213, Percent_Identity=27.6995305164319, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI1787164, Length=191, Percent_Identity=31.9371727748691, Blast_Score=65, Evalue=7e-12,
Organism=Escherichia coli, GI1789962, Length=234, Percent_Identity=24.7863247863248, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI48994883, Length=286, Percent_Identity=23.4265734265734, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1786872, Length=233, Percent_Identity=26.6094420600858, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1789991, Length=192, Percent_Identity=30.2083333333333, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1787712, Length=214, Percent_Identity=27.5700934579439, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1788002, Length=223, Percent_Identity=31.8385650224215, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI87081782, Length=204, Percent_Identity=27.9411764705882, Blast_Score=62, Evalue=4e-11,
Organism=Escherichia coli, GI1786703, Length=197, Percent_Identity=30.4568527918782, Blast_Score=61, Evalue=9e-11,
Organism=Caenorhabditis elegans, GI17565938, Length=261, Percent_Identity=26.4367816091954, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI71983523, Length=220, Percent_Identity=28.1818181818182, Blast_Score=68, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI71983516, Length=220, Percent_Identity=28.1818181818182, Blast_Score=68, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI71983510, Length=220, Percent_Identity=28.1818181818182, Blast_Score=68, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI17543740, Length=199, Percent_Identity=27.1356783919598, Blast_Score=67, Evalue=9e-12,
Organism=Caenorhabditis elegans, GI115533608, Length=209, Percent_Identity=30.622009569378, Blast_Score=65, Evalue=6e-11,
Organism=Drosophila melanogaster, GI85725262, Length=214, Percent_Identity=31.3084112149533, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24650853, Length=244, Percent_Identity=29.5081967213115, Blast_Score=76, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24650855, Length=244, Percent_Identity=29.5081967213115, Blast_Score=76, Evalue=3e-14,
Organism=Drosophila melanogaster, GI281362751, Length=241, Percent_Identity=29.4605809128631, Blast_Score=75, Evalue=5e-14,
Organism=Drosophila melanogaster, GI28574150, Length=215, Percent_Identity=28.3720930232558, Blast_Score=75, Evalue=5e-14,
Organism=Drosophila melanogaster, GI116007328, Length=215, Percent_Identity=28.3720930232558, Blast_Score=75, Evalue=5e-14,
Organism=Drosophila melanogaster, GI24653245, Length=243, Percent_Identity=27.1604938271605, Blast_Score=73, Evalue=3e-13,
Organism=Drosophila melanogaster, GI281363262, Length=243, Percent_Identity=27.1604938271605, Blast_Score=72, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24666092, Length=188, Percent_Identity=29.2553191489362, Blast_Score=68, Evalue=9e-12,
Organism=Drosophila melanogaster, GI24582014, Length=218, Percent_Identity=24.3119266055046, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24582012, Length=218, Percent_Identity=24.3119266055046, Blast_Score=67, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR017882
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 33310; Mature: 33178

Theoretical pI: Translated: 7.57; Mature: 7.57

Prosite motif: PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSADTAAPDLVFDHVHVCQGGRSILDDVYATVPAGSSTVIVGPNGAGKTTLLLCLIGEM
CCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHCCCCCCEEEECCCCCCHHEEEEEECCCC
PYTGRIIAAGRASLPRTAYVPQHLYLDASLPLRVGEFLALNRQRRPLWLGLYGPERAKAR
CCCCEEEECCCCCCCCCCCCCCEEEECCCCCHHHHHHHHHCCCCCCEEEEECCCCHHHHH
DLLRMVRAEQLEERRMSDLSGGETRRVLLAAALDRAPRLLVLDEPAAGVDVQGERLFWEV
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCEEEEEECCCCCCCCCCHHHHHHH
LDEARKQQGFTQLMVSHNLSLAAHYATHIICLNKKVCAEGAPHEALGASTLMQLFGVPIH
HHHHHHHCCHHHHHHHCCCHHEEHHHHEEEEECCHHHCCCCCHHHHHHHHHHHHHCCCEE
LYPDQCDPADPSCPQCGAVCAPERLLPDYASVKRRSEAHRPQDAPAVHAAQGAVKKGKTH
ECCCCCCCCCCCCCCCCCCCCCHHHCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCC
AAKESDHA
CCCCCCCC
>Mature Secondary Structure 
SSADTAAPDLVFDHVHVCQGGRSILDDVYATVPAGSSTVIVGPNGAGKTTLLLCLIGEM
CCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHCCCCCCEEEECCCCCCHHEEEEEECCCC
PYTGRIIAAGRASLPRTAYVPQHLYLDASLPLRVGEFLALNRQRRPLWLGLYGPERAKAR
CCCCEEEECCCCCCCCCCCCCCEEEECCCCCHHHHHHHHHCCCCCCEEEEECCCCHHHHH
DLLRMVRAEQLEERRMSDLSGGETRRVLLAAALDRAPRLLVLDEPAAGVDVQGERLFWEV
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCEEEEEECCCCCCCCCCHHHHHHH
LDEARKQQGFTQLMVSHNLSLAAHYATHIICLNKKVCAEGAPHEALGASTLMQLFGVPIH
HHHHHHHCCHHHHHHHCCCHHEEHHHHEEEEECCHHHCCCCCHHHHHHHHHHHHHCCCEE
LYPDQCDPADPSCPQCGAVCAPERLLPDYASVKRRSEAHRPQDAPAVHAAQGAVKKGKTH
ECCCCCCCCCCCCCCCCCCCCCHHHCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCC
AAKESDHA
CCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Zn (II) [Periplasm]; H2O; ATP [C]

Specific reaction: Zn (II) [Periplasm] + H2O + ATP = Zn (II) [Cytoplasm] + ADP + phosphate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA