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The map label for this gene is prmA [H]

Identifier: 220904277

GI number: 220904277

Start: 1172855

End: 1173703

Strand: Direct

Name: prmA [H]

Synonym: Ddes_1004

Alternate gene names: 220904277

Gene position: 1172855-1173703 (Clockwise)

Preceding gene: 220904273

Following gene: 220904278

Centisome position: 40.82

GC content: 58.54

Gene sequence:

>849_bases
ATGAAGAAGATTTTTCAGCTTGAAGCTATCGTGGGTGAAGACGCCTATGACCAGGCCCTCGGCCTGTTGACCCTGGAAGT
GCCTTTCGGGTGGGAAGAAGAAAGCCTGCCCACCGGTGAAAGCCGCTTTCGTGTGCATTGCGAAAATGCCGACTTTATCC
GGAACCTGTGCAATGTCTTTGAGGTACGCCTGCCCGGGGCCAGATGCGCTGTGCAAAGCCTTGAAGAGCAGGACTGGGTA
GCCGCATGGAAGCAGTTTTTTACTCCTGTACCCTGCGGGCGGCGCTTTGTTGTTCTACCGCCCTGGCTGGCGGACAGTGA
GGAGTTTTCTGACCGCGTCAAGGTGTTCATCGAACCCAAAAGTGCCTTTGGTACCGGCCATCACGCGACCACGGCCCTGT
GCCTCATGGTGCTGAGCGACCTGCTGGATGCGGGGCGCCTGTCGCCCGGCGAAACGTTTCTGGATCTCGGCACGGGGTCC
GGGGTGCTGGGAATTGCCTGCTGCAAGAGCGGCCTACAGGGTGAAGGGCTTGATATTGATTCTCTTGCTGTGGAAAACGC
CCTGGAAAACCGCACGCTCAACGAGGTAGAAGAATTTGCGGTGGGGCAGGGCAGTATAGATGCCGTGCCGGGCAAAACCT
ATGACCTTGTGCTGGCAAATATTCTGGCACGGCCCCTCATTGAGCTTGCTCCGCTTATTGTGCAGGCCTGCAAGCCGGGC
GCGTGCCTTGTGCTTTCGGGGCTGCTTGAAATTCAGGCTGACAGTGTTGAAGCGGCCTACACTGCCCAGTGTCTGCCCAG
GCCCCGGCGCGTGCTGGACGGTGAATGGTGCGCTCTGGTGTGGGATTAG

Upstream 100 bases:

>100_bases
ATTGGTGCTTGTGCCGCCCTCGACCACAGGAAAAAAGTCTGGCATGCTGACCTGGCTTTCCGGCCTGTTACAGTAAAAGA
GACGCAAAAAGAGATGCAAT

Downstream 100 bases:

>100_bases
GCTGTGGCGGGCGGCATGGCTGCTTCGCCTGTTGAAGGCATGCTTGCCGCCCCGGAGTACGGTTCGGGCGTTGCGGCGGC
GGGTCAGTCAGTAATCTGGC

Product: ribosomal L11 methyltransferase

Products: NA

Alternate protein names: L11 Mtase [H]

Number of amino acids: Translated: 282; Mature: 282

Protein sequence:

>282_residues
MKKIFQLEAIVGEDAYDQALGLLTLEVPFGWEEESLPTGESRFRVHCENADFIRNLCNVFEVRLPGARCAVQSLEEQDWV
AAWKQFFTPVPCGRRFVVLPPWLADSEEFSDRVKVFIEPKSAFGTGHHATTALCLMVLSDLLDAGRLSPGETFLDLGTGS
GVLGIACCKSGLQGEGLDIDSLAVENALENRTLNEVEEFAVGQGSIDAVPGKTYDLVLANILARPLIELAPLIVQACKPG
ACLVLSGLLEIQADSVEAAYTAQCLPRPRRVLDGEWCALVWD

Sequences:

>Translated_282_residues
MKKIFQLEAIVGEDAYDQALGLLTLEVPFGWEEESLPTGESRFRVHCENADFIRNLCNVFEVRLPGARCAVQSLEEQDWV
AAWKQFFTPVPCGRRFVVLPPWLADSEEFSDRVKVFIEPKSAFGTGHHATTALCLMVLSDLLDAGRLSPGETFLDLGTGS
GVLGIACCKSGLQGEGLDIDSLAVENALENRTLNEVEEFAVGQGSIDAVPGKTYDLVLANILARPLIELAPLIVQACKPG
ACLVLSGLLEIQADSVEAAYTAQCLPRPRRVLDGEWCALVWD
>Mature_282_residues
MKKIFQLEAIVGEDAYDQALGLLTLEVPFGWEEESLPTGESRFRVHCENADFIRNLCNVFEVRLPGARCAVQSLEEQDWV
AAWKQFFTPVPCGRRFVVLPPWLADSEEFSDRVKVFIEPKSAFGTGHHATTALCLMVLSDLLDAGRLSPGETFLDLGTGS
GVLGIACCKSGLQGEGLDIDSLAVENALENRTLNEVEEFAVGQGSIDAVPGKTYDLVLANILARPLIELAPLIVQACKPG
ACLVLSGLLEIQADSVEAAYTAQCLPRPRRVLDGEWCALVWD

Specific function: Methylates ribosomal protein L11 [H]

COG id: COG2264

COG function: function code J; Ribosomal protein L11 methylase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. PrmA family [H]

Homologues:

Organism=Escherichia coli, GI2367208, Length=216, Percent_Identity=38.8888888888889, Blast_Score=93, Evalue=2e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010456
- InterPro:   IPR004498 [H]

Pfam domain/function: PF06325 PrmA [H]

EC number: 2.1.1.- [C]

Molecular weight: Translated: 30722; Mature: 30722

Theoretical pI: Translated: 4.23; Mature: 4.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.9 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
3.9 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKIFQLEAIVGEDAYDQALGLLTLEVPFGWEEESLPTGESRFRVHCENADFIRNLCNVF
CCCHHHHHHHHCCCHHHHHHEEEEEECCCCCCCCCCCCCCCCEEEEECCHHHHHHHHHHH
EVRLPGARCAVQSLEEQDWVAAWKQFFTPVPCGRRFVVLPPWLADSEEFSDRVKVFIEPK
HHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCHHHHCEEEEEECCH
SAFGTGHHATTALCLMVLSDLLDAGRLSPGETFLDLGTGSGVLGIACCKSGLQGEGLDID
HHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHCCCCCCCCCHH
SLAVENALENRTLNEVEEFAVGQGSIDAVPGKTYDLVLANILARPLIELAPLIVQACKPG
HHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCC
ACLVLSGLLEIQADSVEAAYTAQCLPRPRRVLDGEWCALVWD
HHHHHHHHHHHCCCCCHHHHHHHHCCCCHHHCCCCEEEEEEC
>Mature Secondary Structure
MKKIFQLEAIVGEDAYDQALGLLTLEVPFGWEEESLPTGESRFRVHCENADFIRNLCNVF
CCCHHHHHHHHCCCHHHHHHEEEEEECCCCCCCCCCCCCCCCEEEEECCHHHHHHHHHHH
EVRLPGARCAVQSLEEQDWVAAWKQFFTPVPCGRRFVVLPPWLADSEEFSDRVKVFIEPK
HHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCHHHHCEEEEEECCH
SAFGTGHHATTALCLMVLSDLLDAGRLSPGETFLDLGTGSGVLGIACCKSGLQGEGLDID
HHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHCCCCCCCCCHH
SLAVENALENRTLNEVEEFAVGQGSIDAVPGKTYDLVLANILARPLIELAPLIVQACKPG
HHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCC
ACLVLSGLLEIQADSVEAAYTAQCLPRPRRVLDGEWCALVWD
HHHHHHHHHHHCCCCCHHHHHHHHCCCCHHHCCCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: Catalyzes the methylation of ribosomal protein L11 by S-adenosyl methionine [C]

General reaction: Transferases; Transferring one-carbon groups; Methyltransferases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA