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The map label for this gene is pgi [H]

Identifier: 220904124

GI number: 220904124

Start: 995481

End: 996821

Strand: Direct

Name: pgi [H]

Synonym: Ddes_0851

Alternate gene names: 220904124

Gene position: 995481-996821 (Clockwise)

Preceding gene: 220904123

Following gene: 220904125

Centisome position: 34.64

GC content: 62.71

Gene sequence:

>1341_bases
ATGTCCCATTATCTTGAATGGTCGAGAGCCTACAGTCACAGGTTGAATACGGCGGATGCCGCTCCCCTTCAGGCCAGGGC
TTCTGAAATGGGTCTGCGGCTGGAGCGCGAACTCACGCAGGGCCTTTTGCCCTTTCTGTCCATGCCGTACCGGGCCTCGC
TTGAAAGCGGCCTGCCGCCTGTGCTTGAGCGTATGCGTCCCTGCAGGCACATGCTGGTGCTGGGCATCGGGGGATCCGCC
CTTGGCGCTCGCGCCGTGCAGAAAGCCTTTGCCCCGGGGCAGGACAGGCCGGGGCACACCGGTTCCAGCCTGTGGATTGC
CGACAATGTGTGCGCTGAAGAGTTTGAAGCCCTGCTTGCTGCGCTGCATCCGGCAGAAACGGCCGTGGTATGCATCAGCA
AGTCCGGGGGAACCATTGAAACGCTGGCACAGTATTTTCTTGTGCGGCAATGGCTTCAGGACGCCCTTGGCGAGGGCTGG
CGCGAGCACATGACTGTGGTTACAGACGCCGTGTCCGGTTATCTGCGGCAAGAGGCCTCGAGCTATGGCCTGGCCTCGCT
GGAGGTGCCGGACCATCTGGGGGGCCGTTATTCCGTACTTTCTGCTGTGGGGCTGCTGCCCGCCGCCTTTCTGGGCATTG
ACTGGCGGGCGCTGCTGGACGGCGCGGCCCATGCGGCGCAGCCGCTGGTGGAAAAACCGCGCCGTGTGGGTGAGCATCCT
TCCTATGCCCTTGCCTGCTGGGCCAGGGCGCTGGAAATACAGGACTACAGCGAACTGATCCTTTTCTGCTACGTTCCCCG
GTGGGCCGCCTTCGGGCCGTGGTTTGCGCAGCTGTGGGCCGAAAGCCTGGGCAAGGACGGGCAGGGAATTCTGCCTGTGT
CGGCCACGGGCGTTACGGACCAGCATTCTGTGAACCAGATGTTTCTGGACGGTCGCCGCAACAAGGGCTGCATTTTCCTT
ACCGGCCGGAGACAGCAGCCGGGCCGGGCTTTTGGTCAGGATCTGCCGGAAAAATGGGCATGGCTGCGGGGCAAACCTTT
GGGCGCGCTGCTTGAGGCCGAGGCACTTGGCACACGCATGGCGCTCTGCATGAGCGGTGTGCCGCTGGTTCATCTGGATA
TGGAAGATACCGGTCCCCGGTCTGCCGGGGCTTTCATGCTGCTGCTTGAGGCCGCCACCCTGTTTACCGGCTGGCTCATG
GAGGTGAATCCTCTGGATCAGCCCGCCGTGGAGCTGGGAAAACGTCTTGCCAACGCCCGCCTGGGTGCGCCGGGCTATGA
GCGTGAACAGACGGATCTGGACAGTTTTATGGCCGTACCGTTGCAGGAGCAGGTGTTTTAG

Upstream 100 bases:

>100_bases
ACGGACGTGCTCTGCATCTGCCCGAGGGCGGTGTGTGCATTCCGCACGTTTTAAGGCCGCGCTTTTGCCCCCTGGGCGGC
GCGGTATAAGGGAGAAGCCT

Downstream 100 bases:

>100_bases
GGCATGTGGACGTTCTTTAGAAAAAAACAGGCTCCGCCTCCTGATGCCATTGCTACGGCAAGCGGGCAGGACGGCGCGGC
GCAGGCCGGAAGCGGCCGCG

Product: glucose-6-phosphate isomerase

Products: NA

Alternate protein names: GPI; Phosphoglucose isomerase; PGI; Phosphohexose isomerase; PHI [H]

Number of amino acids: Translated: 446; Mature: 445

Protein sequence:

>446_residues
MSHYLEWSRAYSHRLNTADAAPLQARASEMGLRLERELTQGLLPFLSMPYRASLESGLPPVLERMRPCRHMLVLGIGGSA
LGARAVQKAFAPGQDRPGHTGSSLWIADNVCAEEFEALLAALHPAETAVVCISKSGGTIETLAQYFLVRQWLQDALGEGW
REHMTVVTDAVSGYLRQEASSYGLASLEVPDHLGGRYSVLSAVGLLPAAFLGIDWRALLDGAAHAAQPLVEKPRRVGEHP
SYALACWARALEIQDYSELILFCYVPRWAAFGPWFAQLWAESLGKDGQGILPVSATGVTDQHSVNQMFLDGRRNKGCIFL
TGRRQQPGRAFGQDLPEKWAWLRGKPLGALLEAEALGTRMALCMSGVPLVHLDMEDTGPRSAGAFMLLLEAATLFTGWLM
EVNPLDQPAVELGKRLANARLGAPGYEREQTDLDSFMAVPLQEQVF

Sequences:

>Translated_446_residues
MSHYLEWSRAYSHRLNTADAAPLQARASEMGLRLERELTQGLLPFLSMPYRASLESGLPPVLERMRPCRHMLVLGIGGSA
LGARAVQKAFAPGQDRPGHTGSSLWIADNVCAEEFEALLAALHPAETAVVCISKSGGTIETLAQYFLVRQWLQDALGEGW
REHMTVVTDAVSGYLRQEASSYGLASLEVPDHLGGRYSVLSAVGLLPAAFLGIDWRALLDGAAHAAQPLVEKPRRVGEHP
SYALACWARALEIQDYSELILFCYVPRWAAFGPWFAQLWAESLGKDGQGILPVSATGVTDQHSVNQMFLDGRRNKGCIFL
TGRRQQPGRAFGQDLPEKWAWLRGKPLGALLEAEALGTRMALCMSGVPLVHLDMEDTGPRSAGAFMLLLEAATLFTGWLM
EVNPLDQPAVELGKRLANARLGAPGYEREQTDLDSFMAVPLQEQVF
>Mature_445_residues
SHYLEWSRAYSHRLNTADAAPLQARASEMGLRLERELTQGLLPFLSMPYRASLESGLPPVLERMRPCRHMLVLGIGGSAL
GARAVQKAFAPGQDRPGHTGSSLWIADNVCAEEFEALLAALHPAETAVVCISKSGGTIETLAQYFLVRQWLQDALGEGWR
EHMTVVTDAVSGYLRQEASSYGLASLEVPDHLGGRYSVLSAVGLLPAAFLGIDWRALLDGAAHAAQPLVEKPRRVGEHPS
YALACWARALEIQDYSELILFCYVPRWAAFGPWFAQLWAESLGKDGQGILPVSATGVTDQHSVNQMFLDGRRNKGCIFLT
GRRQQPGRAFGQDLPEKWAWLRGKPLGALLEAEALGTRMALCMSGVPLVHLDMEDTGPRSAGAFMLLLEAATLFTGWLME
VNPLDQPAVELGKRLANARLGAPGYEREQTDLDSFMAVPLQEQVF

Specific function: Involved in glycolysis and in gluconeogenesis. [C]

COG id: COG0166

COG function: function code G; Glucose-6-phosphate isomerase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GPI family [H]

Homologues:

Organism=Homo sapiens, GI18201905, Length=383, Percent_Identity=25.5874673629243, Blast_Score=72, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001672
- InterPro:   IPR018189 [H]

Pfam domain/function: PF00342 PGI [H]

EC number: =5.3.1.9 [H]

Molecular weight: Translated: 48789; Mature: 48657

Theoretical pI: Translated: 5.97; Mature: 5.97

Prosite motif: PS00765 P_GLUCOSE_ISOMERASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSHYLEWSRAYSHRLNTADAAPLQARASEMGLRLERELTQGLLPFLSMPYRASLESGLPP
CCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCHH
VLERMRPCRHMLVLGIGGSALGARAVQKAFAPGQDRPGHTGSSLWIADNVCAEEFEALLA
HHHHHHHHHHEEEEECCCHHHHHHHHHHHCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHH
ALHPAETAVVCISKSGGTIETLAQYFLVRQWLQDALGEGWREHMTVVTDAVSGYLRQEAS
HHCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
SYGLASLEVPDHLGGRYSVLSAVGLLPAAFLGIDWRALLDGAAHAAQPLVEKPRRVGEHP
HCCCEEECCCHHCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCC
SYALACWARALEIQDYSELILFCYVPRWAAFGPWFAQLWAESLGKDGQGILPVSATGVTD
CHHHHHHHHHHHHCCHHHHHHHHCCHHHHHCCHHHHHHHHHHHCCCCCCEEEEECCCCCC
QHSVNQMFLDGRRNKGCIFLTGRRQQPGRAFGQDLPEKWAWLRGKPLGALLEAEALGTRM
CHHHHHHHHCCCCCCCEEEEECCCCCCCHHHHHCCHHHHHHHCCCCHHHHHHHHHHHHHH
ALCMSGVPLVHLDMEDTGPRSAGAFMLLLEAATLFTGWLMEVNPLDQPAVELGKRLANAR
HHHHCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHEECCCCCCHHHHHHHHHHHCC
LGAPGYEREQTDLDSFMAVPLQEQVF
CCCCCCCCHHHHHHHHHHCCHHHHCC
>Mature Secondary Structure 
SHYLEWSRAYSHRLNTADAAPLQARASEMGLRLERELTQGLLPFLSMPYRASLESGLPP
CCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCHH
VLERMRPCRHMLVLGIGGSALGARAVQKAFAPGQDRPGHTGSSLWIADNVCAEEFEALLA
HHHHHHHHHHEEEEECCCHHHHHHHHHHHCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHH
ALHPAETAVVCISKSGGTIETLAQYFLVRQWLQDALGEGWREHMTVVTDAVSGYLRQEAS
HHCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
SYGLASLEVPDHLGGRYSVLSAVGLLPAAFLGIDWRALLDGAAHAAQPLVEKPRRVGEHP
HCCCEEECCCHHCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCC
SYALACWARALEIQDYSELILFCYVPRWAAFGPWFAQLWAESLGKDGQGILPVSATGVTD
CHHHHHHHHHHHHCCHHHHHHHHCCHHHHHCCHHHHHHHHHHHCCCCCCEEEEECCCCCC
QHSVNQMFLDGRRNKGCIFLTGRRQQPGRAFGQDLPEKWAWLRGKPLGALLEAEALGTRM
CHHHHHHHHCCCCCCCEEEEECCCCCCCHHHHHCCHHHHHHHCCCCHHHHHHHHHHHHHH
ALCMSGVPLVHLDMEDTGPRSAGAFMLLLEAATLFTGWLMEVNPLDQPAVELGKRLANAR
HHHHCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHEECCCCCCHHHHHHHHHHHCC
LGAPGYEREQTDLDSFMAVPLQEQVF
CCCCCCCCHHHHHHHHHHCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA