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The map label for this gene is hmcA [H]

Identifier: 220904120

GI number: 220904120

Start: 992678

End: 993082

Strand: Reverse

Name: hmcA [H]

Synonym: Ddes_0847

Alternate gene names: 220904120

Gene position: 993082-992678 (Counterclockwise)

Preceding gene: 220904121

Following gene: 220904119

Centisome position: 34.56

GC content: 56.79

Gene sequence:

>405_bases
ATGCGGGAAAAACACATCGGATTCAGAACCATTCTCACCAGCCTCTTGTTTTTGGCTCTCGGCATGGCACTGTCTTCAGG
CGTGGCCTTCGGTGAGGAACGTATTCCCTTCACCTACCCGGCCTTCAGCGCCAAGAAGATGCCGCCGGTTTTCTTCACCC
ATGACCAGCATATCGCCTATCTGGAAGACAAGGGGCAAGACTGCACCGCCTGCCACCAGATGACGGACGACGGGCTGTCA
GAGACGTTCTTGAATGTAAGAAACGTCGCTCCCGGCAAGCAGGTGGACTACCTGCATGCCACCTGTACCGAGTGTCATGT
CAAGCTTGCCAAAGGCCCCCGCCTTGTAGACTGCCGGGTCTGCCACAGCGAGCGCATCGCATCTGAGTACGCCGCCAAAA
AGTAG

Upstream 100 bases:

>100_bases
CCCGAAGCGCGTGCTCGGGATTTCCTTATATATTGTGCCCGGCGCTGGTTGTTTACCGGGGTAACATCACCAGGATTATG
TCAGGAAGCAAGGATCCACC

Downstream 100 bases:

>100_bases
CCGGTGGCTCACTGCATTAAGGAAGAAAGAACGTTAGGAGGCAGAATCAGATGCTTGACTTTATTACCGGACCCCTGTTT
GTCATTTCACTTGTCATTTT

Product: hypothetical protein

Products: NA

Alternate protein names: Cytochrome CC3 [H]

Number of amino acids: Translated: 134; Mature: 134

Protein sequence:

>134_residues
MREKHIGFRTILTSLLFLALGMALSSGVAFGEERIPFTYPAFSAKKMPPVFFTHDQHIAYLEDKGQDCTACHQMTDDGLS
ETFLNVRNVAPGKQVDYLHATCTECHVKLAKGPRLVDCRVCHSERIASEYAAKK

Sequences:

>Translated_134_residues
MREKHIGFRTILTSLLFLALGMALSSGVAFGEERIPFTYPAFSAKKMPPVFFTHDQHIAYLEDKGQDCTACHQMTDDGLS
ETFLNVRNVAPGKQVDYLHATCTECHVKLAKGPRLVDCRVCHSERIASEYAAKK
>Mature_134_residues
MREKHIGFRTILTSLLFLALGMALSSGVAFGEERIPFTYPAFSAKKMPPVFFTHDQHIAYLEDKGQDCTACHQMTDDGLS
ETFLNVRNVAPGKQVDYLHATCTECHVKLAKGPRLVDCRVCHSERIASEYAAKK

Specific function: HMWC (high-molecular-weight cytochrome c), ORF2, ORF3, ORF4, ORF5 and ORF6 in the HMC operon form a transmembrane protein complex that allows electron flow from the periplasmic hydrogenase to the cytoplasmic enzymes that catalyze reduction of sulfates [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002322
- InterPro:   IPR020942
- InterPro:   IPR011346
- InterPro:   IPR011031 [H]

Pfam domain/function: PF02085 Cytochrom_CIII [H]

EC number: NA

Molecular weight: Translated: 14977; Mature: 14977

Theoretical pI: Translated: 7.86; Mature: 7.86

Prosite motif: PS51008 MULTIHEME_CYTC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.5 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
7.5 %Cys+Met (Translated Protein)
4.5 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
7.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MREKHIGFRTILTSLLFLALGMALSSGVAFGEERIPFTYPAFSAKKMPPVFFTHDQHIAY
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEECCCCCCCCCCCEEEECCCEEEE
LEDKGQDCTACHQMTDDGLSETFLNVRNVAPGKQVDYLHATCTECHVKLAKGPRLVDCRV
ECCCCCCHHHHHHHCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEH
CHSERIASEYAAKK
HHHHHHHHHHHCCC
>Mature Secondary Structure
MREKHIGFRTILTSLLFLALGMALSSGVAFGEERIPFTYPAFSAKKMPPVFFTHDQHIAY
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEECCCCCCCCCCCEEEECCCEEEE
LEDKGQDCTACHQMTDDGLSETFLNVRNVAPGKQVDYLHATCTECHVKLAKGPRLVDCRV
ECCCCCCHHHHHHHCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEH
CHSERIASEYAAKK
HHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1846136; 2163671; 1313289; 8335628; 7925451; 12356749 [H]