Click here to switch to the map view.

The map label for this gene is 220904118

Identifier: 220904118

GI number: 220904118

Start: 990514

End: 991902

Strand: Reverse

Name: 220904118

Synonym: Ddes_0845

Alternate gene names: NA

Gene position: 991902-990514 (Counterclockwise)

Preceding gene: 220904119

Following gene: 220904115

Centisome position: 34.52

GC content: 57.16

Gene sequence:

>1389_bases
ATGTCCGAACTGCTTTGCACCCCCACTCCCATCACCACCAAGGAAGGCATCCTCGAGTTGCTGAAGGACAAGGGCGGGGC
GCAGTACTACAGCCAAATGAAGGAAATGAAGGTCGACCAGGCAGCACTGGCCCGCGACCTGGAGCAGACCTGCAAATCGC
GCACCCGCACGTGGCTCGACATCTGTGCCCACTGCGCCATGTGCGCCGACAGTTGCTTCTTTTACAGAACAAACAATAAT
GACCCCACCCAGATTCCCTCGTACAAGATACAGGCGACCCTGGGCGAGCTCCTGCGCCGCAAGGGCAAGGTCGACGCCGC
TTTCATGATCAAATGCATGGACGCCGCCTGGGGCAAATGCACCTGCTGCAACCGCTGCGCCGTTTACTGCCCGCACGGCA
TCGATACCGGCGTCATGTTCAGCTATCTGCGCGGCATTCTTTTCAAGCACGGCTTCATTCCGTGGGAAATGAAGATCGGC
TCCGGCATGCACCGCGTGTACGGCGCCCAGATGGACGTGAGCGAAGAAGACTGGCTCGAAACCTGTGAATGGATGGTGGA
AGAGCAGCAGGAAGAATGGCCCGACCTCGAAATACCCGTTGAAAAGGAACATGCCGACGTCATGTATGTTCTCAACGCCC
GCGAGGTTAAGCACTATCCTGAAGACATTGCCCTGGCGGCCATCCTCTTCCACGTGACCGACACCAACTGGACCGTGCCG
CGCGAAGGATGGGAAAATACCTCACTGACAATGTTCGCCGGCGACTGGGAAGGCTGTGCGCAGAACGTCAAGCGTATTTA
CGCAGCTGTTGAGCGCATCAAGCCCAAAGTGGTTGTAGGTACCGAATGCGGGCATGCCCACCGCGCCACAGTTATTGAAG
GCCCATACTGGGCCGGACGCGAGAGCGGTGACCCGCCGGTGCGCTTCATGCACTATGTGGAATGGGTGGCAGAAATGCTG
CGCACAGGCAAGATCAAGATAGATCCGGCCAAAAAAATCAAGGTTCCCTGCACACTTCAGGATTCATGCAACTACGTGCG
CAACCACGGCCTTGGTATGGCCACCCGCGAAATCATGAGCTATATTGCTGAAGATTTTCGCGAAATGAGTCCCAAAAGCG
ACCACAATTTCTGTTGCGGCGGGGGCGGCGGCCTCAACGGCATCGGCATTTACCGGCAGGAGCGTAACGTGGCGCTCACC
AACAAGCTGGAGCAGATCAAGGCCACCGGCGCCGAAATGGTCATCACGCCCTGCCACAACTGCTGGGACGCCATCCGCGA
TATGATGGAAGTATATGAAGAGCACAACATCAAGTGGTCTTTCCTCAAGCCGATGCTGGTGGACATGCTGATCATACCGC
CGCACATCCGCCATATTGCGCCTGAGTAG

Upstream 100 bases:

>100_bases
TGGACTTCGCCATTAAAAGAGGCGGAGCTACCCGCGGCGGCGCTTTCCCCTGGTAAAACGGGCAACAGTATTATTATTTT
CGCCTGATAAGGAGCGAACC

Downstream 100 bases:

>100_bases
ACTAAAGTGACAGAACCGCGGTTTATTTGTCCTTTTGCGAATCGCGGTTCTGCCCAAGGGCGCATCATGAACGCCCGTTG
GCCGGGCAAGACATCCCGCT

Product: hypothetical protein

Products: NA

Alternate protein names: HMC operon ORF 6 [H]

Number of amino acids: Translated: 462; Mature: 461

Protein sequence:

>462_residues
MSELLCTPTPITTKEGILELLKDKGGAQYYSQMKEMKVDQAALARDLEQTCKSRTRTWLDICAHCAMCADSCFFYRTNNN
DPTQIPSYKIQATLGELLRRKGKVDAAFMIKCMDAAWGKCTCCNRCAVYCPHGIDTGVMFSYLRGILFKHGFIPWEMKIG
SGMHRVYGAQMDVSEEDWLETCEWMVEEQQEEWPDLEIPVEKEHADVMYVLNAREVKHYPEDIALAAILFHVTDTNWTVP
REGWENTSLTMFAGDWEGCAQNVKRIYAAVERIKPKVVVGTECGHAHRATVIEGPYWAGRESGDPPVRFMHYVEWVAEML
RTGKIKIDPAKKIKVPCTLQDSCNYVRNHGLGMATREIMSYIAEDFREMSPKSDHNFCCGGGGGLNGIGIYRQERNVALT
NKLEQIKATGAEMVITPCHNCWDAIRDMMEVYEEHNIKWSFLKPMLVDMLIIPPHIRHIAPE

Sequences:

>Translated_462_residues
MSELLCTPTPITTKEGILELLKDKGGAQYYSQMKEMKVDQAALARDLEQTCKSRTRTWLDICAHCAMCADSCFFYRTNNN
DPTQIPSYKIQATLGELLRRKGKVDAAFMIKCMDAAWGKCTCCNRCAVYCPHGIDTGVMFSYLRGILFKHGFIPWEMKIG
SGMHRVYGAQMDVSEEDWLETCEWMVEEQQEEWPDLEIPVEKEHADVMYVLNAREVKHYPEDIALAAILFHVTDTNWTVP
REGWENTSLTMFAGDWEGCAQNVKRIYAAVERIKPKVVVGTECGHAHRATVIEGPYWAGRESGDPPVRFMHYVEWVAEML
RTGKIKIDPAKKIKVPCTLQDSCNYVRNHGLGMATREIMSYIAEDFREMSPKSDHNFCCGGGGGLNGIGIYRQERNVALT
NKLEQIKATGAEMVITPCHNCWDAIRDMMEVYEEHNIKWSFLKPMLVDMLIIPPHIRHIAPE
>Mature_461_residues
SELLCTPTPITTKEGILELLKDKGGAQYYSQMKEMKVDQAALARDLEQTCKSRTRTWLDICAHCAMCADSCFFYRTNNND
PTQIPSYKIQATLGELLRRKGKVDAAFMIKCMDAAWGKCTCCNRCAVYCPHGIDTGVMFSYLRGILFKHGFIPWEMKIGS
GMHRVYGAQMDVSEEDWLETCEWMVEEQQEEWPDLEIPVEKEHADVMYVLNAREVKHYPEDIALAAILFHVTDTNWTVPR
EGWENTSLTMFAGDWEGCAQNVKRIYAAVERIKPKVVVGTECGHAHRATVIEGPYWAGRESGDPPVRFMHYVEWVAEMLR
TGKIKIDPAKKIKVPCTLQDSCNYVRNHGLGMATREIMSYIAEDFREMSPKSDHNFCCGGGGGLNGIGIYRQERNVALTN
KLEQIKATGAEMVITPCHNCWDAIRDMMEVYEEHNIKWSFLKPMLVDMLIIPPHIRHIAPE

Specific function: HMWC (high-molecular-weight cytochrome c precursor), ORF2, ORF3, ORF4, ORF5, ORF6 in the HMC operon form a transmembrane protein complex that allows electron flow from the periplasmic hydrogenase to the cytoplasmic enzymes that catalyze reduction of sulfa

COG id: COG0247

COG function: function code C; Fe-S oxidoreductase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 2 4Fe-4S ferredoxin-type domains [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017900
- InterPro:   IPR004017
- InterPro:   IPR012285 [H]

Pfam domain/function: PF02754 CCG [H]

EC number: NA

Molecular weight: Translated: 52657; Mature: 52526

Theoretical pI: Translated: 6.20; Mature: 6.20

Prosite motif: PS00018 EF_HAND_1 ; PS00198 4FE4S_FERREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.5 %Cys     (Translated Protein)
5.0 %Met     (Translated Protein)
9.5 %Cys+Met (Translated Protein)
4.6 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
9.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSELLCTPTPITTKEGILELLKDKGGAQYYSQMKEMKVDQAALARDLEQTCKSRTRTWLD
CCCCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ICAHCAMCADSCFFYRTNNNDPTQIPSYKIQATLGELLRRKGKVDAAFMIKCMDAAWGKC
HHHHHHHHHCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCC
TCCNRCAVYCPHGIDTGVMFSYLRGILFKHGFIPWEMKIGSGMHRVYGAQMDVSEEDWLE
CCCCCCEEECCCCCCHHHHHHHHHHHHHHCCCCCEEEECCCCHHHHHCCCCCCCHHHHHH
TCEWMVEEQQEEWPDLEIPVEKEHADVMYVLNAREVKHYPEDIALAAILFHVTDTNWTVP
HHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEECHHHHHCCHHHHHHHHHHEEECCCCCCC
REGWENTSLTMFAGDWEGCAQNVKRIYAAVERIKPKVVVGTECGHAHRATVIEGPYWAGR
CCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCEEECCCCCCCC
ESGDPPVRFMHYVEWVAEMLRTGKIKIDPAKKIKVPCTLQDSCNYVRNHGLGMATREIMS
CCCCCHHHHHHHHHHHHHHHHCCCEEECCCCCEEECEEEHHHHHHHHHCCCCHHHHHHHH
YIAEDFREMSPKSDHNFCCGGGGGLNGIGIYRQERNVALTNKLEQIKATGAEMVITPCHN
HHHHHHHHCCCCCCCCEEECCCCCCCCCEEEEECCCCHHHHHHHHHHHCCCCEEEECCHH
CWDAIRDMMEVYEEHNIKWSFLKPMLVDMLIIPPHIRHIAPE
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCHHHHCCCC
>Mature Secondary Structure 
SELLCTPTPITTKEGILELLKDKGGAQYYSQMKEMKVDQAALARDLEQTCKSRTRTWLD
CCCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ICAHCAMCADSCFFYRTNNNDPTQIPSYKIQATLGELLRRKGKVDAAFMIKCMDAAWGKC
HHHHHHHHHCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCC
TCCNRCAVYCPHGIDTGVMFSYLRGILFKHGFIPWEMKIGSGMHRVYGAQMDVSEEDWLE
CCCCCCEEECCCCCCHHHHHHHHHHHHHHCCCCCEEEECCCCHHHHHCCCCCCCHHHHHH
TCEWMVEEQQEEWPDLEIPVEKEHADVMYVLNAREVKHYPEDIALAAILFHVTDTNWTVP
HHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEECHHHHHCCHHHHHHHHHHEEECCCCCCC
REGWENTSLTMFAGDWEGCAQNVKRIYAAVERIKPKVVVGTECGHAHRATVIEGPYWAGR
CCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCEEECCCCCCCC
ESGDPPVRFMHYVEWVAEMLRTGKIKIDPAKKIKVPCTLQDSCNYVRNHGLGMATREIMS
CCCCCHHHHHHHHHHHHHHHHCCCEEECCCCCEEECEEEHHHHHHHHHCCCCHHHHHHHH
YIAEDFREMSPKSDHNFCCGGGGGLNGIGIYRQERNVALTNKLEQIKATGAEMVITPCHN
HHHHHHHHCCCCCCCCEEECCCCCCCCCEEEEECCCCHHHHHHHHHHHCCCCEEEECCHH
CWDAIRDMMEVYEEHNIKWSFLKPMLVDMLIIPPHIRHIAPE
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8335628 [H]