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The map label for this gene is 220904078

Identifier: 220904078

GI number: 220904078

Start: 940839

End: 942023

Strand: Reverse

Name: 220904078

Synonym: Ddes_0804

Alternate gene names: NA

Gene position: 942023-940839 (Counterclockwise)

Preceding gene: 220904079

Following gene: 220904077

Centisome position: 32.78

GC content: 62.03

Gene sequence:

>1185_bases
ATGCTTAACAAGTTTCGCCTGCTCACCCCCGGCCCCACGCCCCTGCCCGAGCGCGTGCGCCTTGTTCTGGCCCGGGACAT
GATCCACCATCGCAAAAGCGAATTCAAAGAGATCATGGGGCAGGTTCAGCAAAGCCTGCAAACACTTTTCGGCACTTCCG
GCACGGTGCTGCCTCTCTCCTGTTCCGGCACGGGGGCCATGACGGCAGCCGTGTACAATCTTTTCGCGCCGGGGCAAAAA
GTGCTGGTGATCGACGGTGGCAAATTCAGCCAGCGCTGGAGTGAAATTGCCCTGTCGCGCGGCCTGGAAGTAGAAACCAT
CCCTGTGCCGTGGGGCCAGGCCGTCAGGCCTGAAGCCGTGGAAGCGGCCCTCAAGGCGGACCCGTCCATTGCCGGAGTGC
TTATCCAGCTTTCCGAAACATCCACCGGTGTACTTCACCCTGTGGAGGCCGTGGCCCGCATCACCCGCGAAAGCCAGGCC
CTGCTGGTAGTGGACGGCATCTCGGCAGTGGGCCTTTCACCCTGCCCCATGGATGCATGGGGAGTGGACTGCCTGCTCAC
CGGCTCGCAAAAAGGCCTCATGCTGCCCCCTGGCCTGGCGCTGCTGGCGCTGTCCGGGCGGGCCTGGGCCTGTGCCGAAA
AGCAGACGCCGGGCTGTTTTTACTTCAATCTGGTCAAAGAGCGCGAGAATGTGCTCAAGGGGCAAACCTGCTTTACTTCT
CCTGTGGGACTTATCCTCGGACTCAAGGAAAGCCTGGACATGCTGCTGGAAAACGGGCTGGAACCCGTGTATGCCAAGCA
ATGGGCCTTGACCATGCTCACCCGCGCAGGCCTTTCGGCCATGGGGCTGGAACTGTTTGCCAAAAAAGATTTTGCGTGGG
GCATCACCAGCGTACTGCTGCCTGACGGAGTTGATGGCACAAAGGTATTGCGTCTGGCTCAGGAAAAACACGGCGTATGT
ATGGCCGGGGGGCAGGACCACTACAAGGGGCGCATGGCGCGCATCGGCCATATGGGATGGGTGGACTGGGCGGATGTGGC
CGCCGGCCTTTACGCCCTCAACGACAGCCTGCGGGCCGTGGGCGGCTACAGCGGCTCGCGCGACTATCTGGAGCAGGGCA
TGGCCGCCTATCGTGCAGCCCTTGAAGGCAGGCCCGGCGCTCCGTTGCCTCAGGTCTATAGCTAG

Upstream 100 bases:

>100_bases
CGCAACGCCGGGCACGGCGGCGCGAAACGGCGAAAAAACGTGTGCGGCCCCGGCATGGCACAAAAGCATTTACGGAACGC
AAAACATAAGGAACAGCCAC

Downstream 100 bases:

>100_bases
AGCAGCTTCACCTTGAGATGTCTGTTCTCAAGGTTTTCAGAACGCTCATTACGGCGCCTGACAGCGCCACTGCATTGCTC
CTGAGCCGCTTCACCCTGAG

Product: class V aminotransferase

Products: NA

Alternate protein names: Tritium exchange subunit [H]

Number of amino acids: Translated: 394; Mature: 394

Protein sequence:

>394_residues
MLNKFRLLTPGPTPLPERVRLVLARDMIHHRKSEFKEIMGQVQQSLQTLFGTSGTVLPLSCSGTGAMTAAVYNLFAPGQK
VLVIDGGKFSQRWSEIALSRGLEVETIPVPWGQAVRPEAVEAALKADPSIAGVLIQLSETSTGVLHPVEAVARITRESQA
LLVVDGISAVGLSPCPMDAWGVDCLLTGSQKGLMLPPGLALLALSGRAWACAEKQTPGCFYFNLVKERENVLKGQTCFTS
PVGLILGLKESLDMLLENGLEPVYAKQWALTMLTRAGLSAMGLELFAKKDFAWGITSVLLPDGVDGTKVLRLAQEKHGVC
MAGGQDHYKGRMARIGHMGWVDWADVAAGLYALNDSLRAVGGYSGSRDYLEQGMAAYRAALEGRPGAPLPQVYS

Sequences:

>Translated_394_residues
MLNKFRLLTPGPTPLPERVRLVLARDMIHHRKSEFKEIMGQVQQSLQTLFGTSGTVLPLSCSGTGAMTAAVYNLFAPGQK
VLVIDGGKFSQRWSEIALSRGLEVETIPVPWGQAVRPEAVEAALKADPSIAGVLIQLSETSTGVLHPVEAVARITRESQA
LLVVDGISAVGLSPCPMDAWGVDCLLTGSQKGLMLPPGLALLALSGRAWACAEKQTPGCFYFNLVKERENVLKGQTCFTS
PVGLILGLKESLDMLLENGLEPVYAKQWALTMLTRAGLSAMGLELFAKKDFAWGITSVLLPDGVDGTKVLRLAQEKHGVC
MAGGQDHYKGRMARIGHMGWVDWADVAAGLYALNDSLRAVGGYSGSRDYLEQGMAAYRAALEGRPGAPLPQVYS
>Mature_394_residues
MLNKFRLLTPGPTPLPERVRLVLARDMIHHRKSEFKEIMGQVQQSLQTLFGTSGTVLPLSCSGTGAMTAAVYNLFAPGQK
VLVIDGGKFSQRWSEIALSRGLEVETIPVPWGQAVRPEAVEAALKADPSIAGVLIQLSETSTGVLHPVEAVARITRESQA
LLVVDGISAVGLSPCPMDAWGVDCLLTGSQKGLMLPPGLALLALSGRAWACAEKQTPGCFYFNLVKERENVLKGQTCFTS
PVGLILGLKESLDMLLENGLEPVYAKQWALTMLTRAGLSAMGLELFAKKDFAWGITSVLLPDGVDGTKVLRLAQEKHGVC
MAGGQDHYKGRMARIGHMGWVDWADVAAGLYALNDSLRAVGGYSGSRDYLEQGMAAYRAALEGRPGAPLPQVYS

Specific function: Soluble hydrogenase catalyzes both production and consumption of hydrogen from suitable artificial electron donors or acceptors. This subunit catalyzes the tritium-exchange activity [H]

COG id: COG0075

COG function: function code E; Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI4557289, Length=345, Percent_Identity=30.4347826086957, Blast_Score=134, Evalue=1e-31,
Organism=Caenorhabditis elegans, GI17536281, Length=344, Percent_Identity=31.3953488372093, Blast_Score=148, Evalue=6e-36,
Organism=Saccharomyces cerevisiae, GI6321079, Length=361, Percent_Identity=28.808864265928, Blast_Score=115, Evalue=2e-26,
Organism=Drosophila melanogaster, GI17530823, Length=373, Percent_Identity=27.8820375335121, Blast_Score=130, Evalue=2e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000192
- InterPro:   IPR020578
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: 2.6.1.-

Molecular weight: Translated: 42246; Mature: 42246

Theoretical pI: Translated: 7.78; Mature: 7.78

Prosite motif: PS00595 AA_TRANSFER_CLASS_5

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNKFRLLTPGPTPLPERVRLVLARDMIHHRKSEFKEIMGQVQQSLQTLFGTSGTVLPLS
CCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEE
CSGTGAMTAAVYNLFAPGQKVLVIDGGKFSQRWSEIALSRGLEVETIPVPWGQAVRPEAV
CCCCCHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHCCCEEEEECCCCCCCCCHHHH
EAALKADPSIAGVLIQLSETSTGVLHPVEAVARITRESQALLVVDGISAVGLSPCPMDAW
HHHHHCCCCEEEEEEEECCCCCCCCHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCC
GVDCLLTGSQKGLMLPPGLALLALSGRAWACAEKQTPGCFYFNLVKERENVLKGQTCFTS
CCEEEEECCCCCCCCCCCCEEEEECCCEEEECCCCCCCEEEHHHHHHHHHHHCCCCHHCC
PVGLILGLKESLDMLLENGLEPVYAKQWALTMLTRAGLSAMGLELFAKKDFAWGITSVLL
CHHHHHCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHCHHHHHHHHHHCCCCHHCHHHHHC
PDGVDGTKVLRLAQEKHGVCMAGGQDHYKGRMARIGHMGWVDWADVAAGLYALNDSLRAV
CCCCCHHHHHHHHHHHCCEEEECCCHHHCCHHHHHCCCCCCCHHHHHHHHHHHCCHHHHH
GGYSGSRDYLEQGMAAYRAALEGRPGAPLPQVYS
CCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure
MLNKFRLLTPGPTPLPERVRLVLARDMIHHRKSEFKEIMGQVQQSLQTLFGTSGTVLPLS
CCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEE
CSGTGAMTAAVYNLFAPGQKVLVIDGGKFSQRWSEIALSRGLEVETIPVPWGQAVRPEAV
CCCCCHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHCCCEEEEECCCCCCCCCHHHH
EAALKADPSIAGVLIQLSETSTGVLHPVEAVARITRESQALLVVDGISAVGLSPCPMDAW
HHHHHCCCCEEEEEEEECCCCCCCCHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCC
GVDCLLTGSQKGLMLPPGLALLALSGRAWACAEKQTPGCFYFNLVKERENVLKGQTCFTS
CCEEEEECCCCCCCCCCCCEEEEECCCEEEECCCCCCCEEEHHHHHHHHHHHCCCCHHCC
PVGLILGLKESLDMLLENGLEPVYAKQWALTMLTRAGLSAMGLELFAKKDFAWGITSVLL
CHHHHHCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHCHHHHHHHHHHCCCCHHCHHHHHC
PDGVDGTKVLRLAQEKHGVCMAGGQDHYKGRMARIGHMGWVDWADVAAGLYALNDSLRAV
CCCCCHHHHHHHHHHHCCEEEECCCHHHCCHHHHHCCCCCCCHHHHHHHHHHHCCHHHHH
GGYSGSRDYLEQGMAAYRAALEGRPGAPLPQVYS
CCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2513553 [H]