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The map label for this gene is yabD [H]

Identifier: 220904054

GI number: 220904054

Start: 914146

End: 914967

Strand: Direct

Name: yabD [H]

Synonym: Ddes_0780

Alternate gene names: 220904054

Gene position: 914146-914967 (Clockwise)

Preceding gene: 220904044

Following gene: 220904055

Centisome position: 31.81

GC content: 61.44

Gene sequence:

>822_bases
ATGTCGAAAAAATCCACCAACCGCATTGATCCCGTTTCTGTTCCCCTGCCGCCGGAAGGTGTCGACAGCCACGCCCATCT
GGACGGCGAGGAGTTTGACCTGGACCGTGAAGCCGTACTGGAAAGGGCCGCTGCCTGCGGCGTAAGCCATGTGGGCAATG
TCTTTCTCAATCCCGGCCATCTCGCCGCCCGGCGGCACTATTTTGCGGATCACCCGCAGGTTTTCTTTCTGCTTGGCGTG
CACCCCTGCCATGGGCGGGACTGCACGCCCCAGGTTATCGAAGCCATGCGCCAGGCCTTTGCAGAAGAGCCGCGCCTCAA
GGCCGTGGGTGAAATCGGCCTGGATTTTTATTGGGACGATTGCCCCCGCGAAGTACAGTACGAGGTTTTTACCGCGCAGC
TCAGGCTGGCCCGTGAGCTGGAGCGTCCTGTGGTGATTCACTGCCGTGAGGCTGAAAAAGAAACGCTCATGGTTCTGGAG
TCGCAGGGTTTCGCCGGTTATCCGCTACTGTGGCACTGTTTTGGCAAAGGACCGGACCTGGCCCGGCGCATCGTGCGCAA
CGGCTGGCATGTATCTGTACCCGGCCCCGTGACCTACAAGGCAAATGAAGAGCTGCGCGAAGCCGTAGCCTGCATTCCCT
CCGACCGGCTCATGCTGGAAACCGACGCTCCGTATCTAGCTCCTGTACCCTGGCGCGGCAAGCGCAACGAGCCTGCCTTT
ACAGTGTTTACGGCGCGGGCGGTGGCGGAAGCGCGCGGGCAGGATGCGGAAGAACTGTGGCGGCAGTGCGGTGCCAATGC
CCGGCGGTTTTTCGGCCTGTAG

Upstream 100 bases:

>100_bases
ACCAGTTCAGCATAGCGCTATTGCCCTGTCTTGGCAATGGCGCTGCTGCCGGGCCTTGCCCTTGCCCGCGCACGTTGTTA
TGTAACGGCGCGAGGTAAAC

Downstream 100 bases:

>100_bases
CCAGTGCCGTCACGTATACCTTTCATGATATCTCTGCGTCGAATTTTTCCTTGATATGACAGGCAAAATCATTTCGGGAC
GACACGGTTTCGGGCGGGGA

Product: hydrolase, TatD family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 273; Mature: 272

Protein sequence:

>273_residues
MSKKSTNRIDPVSVPLPPEGVDSHAHLDGEEFDLDREAVLERAAACGVSHVGNVFLNPGHLAARRHYFADHPQVFFLLGV
HPCHGRDCTPQVIEAMRQAFAEEPRLKAVGEIGLDFYWDDCPREVQYEVFTAQLRLARELERPVVIHCREAEKETLMVLE
SQGFAGYPLLWHCFGKGPDLARRIVRNGWHVSVPGPVTYKANEELREAVACIPSDRLMLETDAPYLAPVPWRGKRNEPAF
TVFTARAVAEARGQDAEELWRQCGANARRFFGL

Sequences:

>Translated_273_residues
MSKKSTNRIDPVSVPLPPEGVDSHAHLDGEEFDLDREAVLERAAACGVSHVGNVFLNPGHLAARRHYFADHPQVFFLLGV
HPCHGRDCTPQVIEAMRQAFAEEPRLKAVGEIGLDFYWDDCPREVQYEVFTAQLRLARELERPVVIHCREAEKETLMVLE
SQGFAGYPLLWHCFGKGPDLARRIVRNGWHVSVPGPVTYKANEELREAVACIPSDRLMLETDAPYLAPVPWRGKRNEPAF
TVFTARAVAEARGQDAEELWRQCGANARRFFGL
>Mature_272_residues
SKKSTNRIDPVSVPLPPEGVDSHAHLDGEEFDLDREAVLERAAACGVSHVGNVFLNPGHLAARRHYFADHPQVFFLLGVH
PCHGRDCTPQVIEAMRQAFAEEPRLKAVGEIGLDFYWDDCPREVQYEVFTAQLRLARELERPVVIHCREAEKETLMVLES
QGFAGYPLLWHCFGKGPDLARRIVRNGWHVSVPGPVTYKANEELREAVACIPSDRLMLETDAPYLAPVPWRGKRNEPAFT
VFTARAVAEARGQDAEELWRQCGANARRFFGL

Specific function: Unknown

COG id: COG0084

COG function: function code L; Mg-dependent DNase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tatD DNase family [H]

Homologues:

Organism=Homo sapiens, GI110349734, Length=269, Percent_Identity=31.5985130111524, Blast_Score=103, Evalue=2e-22,
Organism=Homo sapiens, GI110349730, Length=269, Percent_Identity=31.2267657992565, Blast_Score=102, Evalue=5e-22,
Organism=Homo sapiens, GI226061853, Length=275, Percent_Identity=31.2727272727273, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI226061614, Length=258, Percent_Identity=30.2325581395349, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI225903424, Length=206, Percent_Identity=31.0679611650485, Blast_Score=88, Evalue=8e-18,
Organism=Homo sapiens, GI226061595, Length=232, Percent_Identity=31.8965517241379, Blast_Score=84, Evalue=1e-16,
Organism=Escherichia coli, GI1787342, Length=257, Percent_Identity=37.7431906614786, Blast_Score=157, Evalue=5e-40,
Organism=Escherichia coli, GI87082439, Length=254, Percent_Identity=29.1338582677165, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI48994985, Length=257, Percent_Identity=30.7392996108949, Blast_Score=106, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI17559024, Length=286, Percent_Identity=29.3706293706294, Blast_Score=110, Evalue=7e-25,
Organism=Caenorhabditis elegans, GI71980746, Length=260, Percent_Identity=28.4615384615385, Blast_Score=96, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17543026, Length=186, Percent_Identity=32.258064516129, Blast_Score=85, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI17565396, Length=184, Percent_Identity=30.9782608695652, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24648690, Length=287, Percent_Identity=24.390243902439, Blast_Score=70, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015992
- InterPro:   IPR001130
- InterPro:   IPR018228
- InterPro:   IPR012278
- InterPro:   IPR015991 [H]

Pfam domain/function: PF01026 TatD_DNase [H]

EC number: 3.1.21.-

Molecular weight: Translated: 30750; Mature: 30619

Theoretical pI: Translated: 6.29; Mature: 6.29

Prosite motif: PS01091 TATD_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.9 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
2.9 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKKSTNRIDPVSVPLPPEGVDSHAHLDGEEFDLDREAVLERAAACGVSHVGNVFLNPGH
CCCCCCCCCCCEECCCCCCCCCCCCCCCCHHCCCCHHHHHHHHHHCCHHHHCCEEECCCH
LAARRHYFADHPQVFFLLGVHPCHGRDCTPQVIEAMRQAFAEEPRLKAVGEIGLDFYWDD
HHHHHHHCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHCCCEEEECC
CPREVQYEVFTAQLRLARELERPVVIHCREAEKETLMVLESQGFAGYPLLWHCFGKGPDL
CCCHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCEEEEEECCCCCCCCHHEEECCCCHHH
ARRIVRNGWHVSVPGPVTYKANEELREAVACIPSDRLMLETDAPYLAPVPWRGKRNEPAF
HHHHHHCCCEEECCCCEEECCCHHHHHHHHHCCCCCEEEECCCCEECCCCCCCCCCCCCE
TVFTARAVAEARGQDAEELWRQCGANARRFFGL
EEEHHHHHHHHCCCCHHHHHHHHCCCCHHHCCC
>Mature Secondary Structure 
SKKSTNRIDPVSVPLPPEGVDSHAHLDGEEFDLDREAVLERAAACGVSHVGNVFLNPGH
CCCCCCCCCCEECCCCCCCCCCCCCCCCHHCCCCHHHHHHHHHHCCHHHHCCEEECCCH
LAARRHYFADHPQVFFLLGVHPCHGRDCTPQVIEAMRQAFAEEPRLKAVGEIGLDFYWDD
HHHHHHHCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHCCCEEEECC
CPREVQYEVFTAQLRLARELERPVVIHCREAEKETLMVLESQGFAGYPLLWHCFGKGPDL
CCCHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCEEEEEECCCCCCCCHHEEECCCCHHH
ARRIVRNGWHVSVPGPVTYKANEELREAVACIPSDRLMLETDAPYLAPVPWRGKRNEPAF
HHHHHHCCCEEECCCCEEECCCHHHHHHHHHCCCCCEEEECCCCEECCCCCCCCCCCCCE
TVFTARAVAEARGQDAEELWRQCGANARRFFGL
EEEHHHHHHHHCCCCHHHHHHHHCCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]