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The map label for this gene is pucG [H]

Identifier: 220903916

GI number: 220903916

Start: 778155

End: 779267

Strand: Reverse

Name: pucG [H]

Synonym: Ddes_0641

Alternate gene names: 220903916

Gene position: 779267-778155 (Counterclockwise)

Preceding gene: 220903924

Following gene: 220903914

Centisome position: 27.12

GC content: 61.46

Gene sequence:

>1113_bases
ATGAGTACAGTTTTGGGATCGCTTGACCATGTTCTGCTGATGGCCCCCGGCCCCAGCCCCGTTGCCACCAACGTTCTCCA
GGCCATGAGCCTGCCCACCCTGGGGCATCTTGACCCCGACTGCATCAAGGTTATGGATGCCATCCAGGACCAGCTGCGGG
CCGTGTGCAAAACCGGCAACGTGGTAACCTTTCCCCTGTCGGGCACCGGCTCTGCGGGTATGGAAGCATGCTTTGTGAAC
CTGGTGGAACCGGGCGATGCCGTGCTTGTCGTCAACAACGGCGTATTCAGTTCGCGCATGGTAGAGGTGGCTTCGCGCCT
GGGCGCAGAGGTGGACGTGGTTGAAAGCCCCTGGGGTACTCCCGTAAAGGTCGAGGACGTCAAAACCCAGCTGGGCAAAA
AACACTACAAGATCCTGGCCGTGGTGCATGCCGAGACATCAACGGGCGTCAACAACCCCATTGCCGAGATCGGTGAGCTG
GTCAAGGGCAGCGACACTCTTTATATGGTAGACAGCGTGGCCGGACTCGGCGGCGTGGACATGCAGGTGGACAACTGGGG
CGTGGACGCTTTTTACAGTGGTTCGCAAAAGTGCCTTTCCGTACCTCCCGGCCTTGCTCCCGCCTCTTTCTCCGAGGCCG
CCATGGACGCCATGGCCAGGCGCAAGCACAAAGTACCCAACTGGTACCTTGATGTTTCACTCATCCGCAAATACTGGGAA
GGCTCCCCCCGCGTATACCACCATACCGCGCCCATCAACATGTACTACGGCCTGCACCAGGCGCTGGACAACCTGCTGAC
GGAAGGGCTGGACGCGGCCTTTGCACGGCACAAGGCCATGCATCACCGCCTGGCGGACGGCCTGGCAGAACTGGGCTTCA
GCCTGTATGTAAAGGAAGGCGCGGCACCTCAGGTGAACCTTTTCATTCCTCCCGCCGGCGTGGACGCCAACGCCCTGCGC
GCCTGCCTGCGCGAAAAGCACAAGATTGAAGTGGCGGGCGGCCTTGGGGCGCTTGCCGGTAAGGTTATCCGCGTGGGCGT
TATGGGCGAAGGCGCACGGCCCGAAGCCATTGACAAACTGCTTGCCGCTGTCCGGGCCTGCCTCGGCCGGTAG

Upstream 100 bases:

>100_bases
AAAAATTTTAAGCTGCGTACCGCGCAGCGGACGTCCGTCTGTACGGACGTCGAAATACCCAGCCCTGACGAGTATTAGCC
GTCAACCACAGGAGACTGCC

Downstream 100 bases:

>100_bases
CCCTTGCAACCAGGAGCGCGCGCGGGGCACCCGCCGCGCGCGCTTCGCTTTCAGACCTTTTTTCCATCAATTTTTTTCAT
GCCCGACGCATTTTTTCCAC

Product: Alanine--glyoxylate transaminase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 370; Mature: 369

Protein sequence:

>370_residues
MSTVLGSLDHVLLMAPGPSPVATNVLQAMSLPTLGHLDPDCIKVMDAIQDQLRAVCKTGNVVTFPLSGTGSAGMEACFVN
LVEPGDAVLVVNNGVFSSRMVEVASRLGAEVDVVESPWGTPVKVEDVKTQLGKKHYKILAVVHAETSTGVNNPIAEIGEL
VKGSDTLYMVDSVAGLGGVDMQVDNWGVDAFYSGSQKCLSVPPGLAPASFSEAAMDAMARRKHKVPNWYLDVSLIRKYWE
GSPRVYHHTAPINMYYGLHQALDNLLTEGLDAAFARHKAMHHRLADGLAELGFSLYVKEGAAPQVNLFIPPAGVDANALR
ACLREKHKIEVAGGLGALAGKVIRVGVMGEGARPEAIDKLLAAVRACLGR

Sequences:

>Translated_370_residues
MSTVLGSLDHVLLMAPGPSPVATNVLQAMSLPTLGHLDPDCIKVMDAIQDQLRAVCKTGNVVTFPLSGTGSAGMEACFVN
LVEPGDAVLVVNNGVFSSRMVEVASRLGAEVDVVESPWGTPVKVEDVKTQLGKKHYKILAVVHAETSTGVNNPIAEIGEL
VKGSDTLYMVDSVAGLGGVDMQVDNWGVDAFYSGSQKCLSVPPGLAPASFSEAAMDAMARRKHKVPNWYLDVSLIRKYWE
GSPRVYHHTAPINMYYGLHQALDNLLTEGLDAAFARHKAMHHRLADGLAELGFSLYVKEGAAPQVNLFIPPAGVDANALR
ACLREKHKIEVAGGLGALAGKVIRVGVMGEGARPEAIDKLLAAVRACLGR
>Mature_369_residues
STVLGSLDHVLLMAPGPSPVATNVLQAMSLPTLGHLDPDCIKVMDAIQDQLRAVCKTGNVVTFPLSGTGSAGMEACFVNL
VEPGDAVLVVNNGVFSSRMVEVASRLGAEVDVVESPWGTPVKVEDVKTQLGKKHYKILAVVHAETSTGVNNPIAEIGELV
KGSDTLYMVDSVAGLGGVDMQVDNWGVDAFYSGSQKCLSVPPGLAPASFSEAAMDAMARRKHKVPNWYLDVSLIRKYWEG
SPRVYHHTAPINMYYGLHQALDNLLTEGLDAAFARHKAMHHRLADGLAELGFSLYVKEGAAPQVNLFIPPAGVDANALRA
CLREKHKIEVAGGLGALAGKVIRVGVMGEGARPEAIDKLLAAVRACLGR

Specific function: Could encode ureidoglycolase or L-alanine:glyoxylate aminotransferase, or perhaps both activities [H]

COG id: COG0075

COG function: function code E; Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI4557289, Length=366, Percent_Identity=36.3387978142077, Blast_Score=241, Evalue=6e-64,
Organism=Caenorhabditis elegans, GI17536281, Length=361, Percent_Identity=36.8421052631579, Blast_Score=241, Evalue=3e-64,
Organism=Saccharomyces cerevisiae, GI6321079, Length=383, Percent_Identity=28.7206266318538, Blast_Score=133, Evalue=3e-32,
Organism=Drosophila melanogaster, GI17530823, Length=355, Percent_Identity=39.7183098591549, Blast_Score=270, Evalue=1e-72,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000192
- InterPro:   IPR020578
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: 2.6.1.-

Molecular weight: Translated: 39280; Mature: 39149

Theoretical pI: Translated: 6.65; Mature: 6.65

Prosite motif: PS00595 AA_TRANSFER_CLASS_5

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTVLGSLDHVLLMAPGPSPVATNVLQAMSLPTLGHLDPDCIKVMDAIQDQLRAVCKTGN
CCCHHCCCCCEEEECCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCC
VVTFPLSGTGSAGMEACFVNLVEPGDAVLVVNNGVFSSRMVEVASRLGAEVDVVESPWGT
EEEEECCCCCCCCHHHHEEEEECCCCEEEEEECCCHHHHHHHHHHHCCCCEEEEECCCCC
PVKVEDVKTQLGKKHYKILAVVHAETSTGVNNPIAEIGELVKGSDTLYMVDSVAGLGGVD
CEEHHHHHHHHCCCEEEEEEEEEECCCCCCCCCHHHHHHHHCCCCCEEEEECCCCCCCCE
MQVDNWGVDAFYSGSQKCLSVPPGLAPASFSEAAMDAMARRKHKVPNWYLDVSLIRKYWE
EEECCCCCCEEECCCCCEECCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHC
GSPRVYHHTAPINMYYGLHQALDNLLTEGLDAAFARHKAMHHRLADGLAELGFSLYVKEG
CCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECC
AAPQVNLFIPPAGVDANALRACLREKHKIEVAGGLGALAGKVIRVGVMGEGARPEAIDKL
CCCEEEEEECCCCCCHHHHHHHHHHCCEEEEECCHHHHHHHEEEEEECCCCCCHHHHHHH
LAAVRACLGR
HHHHHHHHCC
>Mature Secondary Structure 
STVLGSLDHVLLMAPGPSPVATNVLQAMSLPTLGHLDPDCIKVMDAIQDQLRAVCKTGN
CCHHCCCCCEEEECCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCC
VVTFPLSGTGSAGMEACFVNLVEPGDAVLVVNNGVFSSRMVEVASRLGAEVDVVESPWGT
EEEEECCCCCCCCHHHHEEEEECCCCEEEEEECCCHHHHHHHHHHHCCCCEEEEECCCCC
PVKVEDVKTQLGKKHYKILAVVHAETSTGVNNPIAEIGELVKGSDTLYMVDSVAGLGGVD
CEEHHHHHHHHCCCEEEEEEEEEECCCCCCCCCHHHHHHHHCCCCCEEEEECCCCCCCCE
MQVDNWGVDAFYSGSQKCLSVPPGLAPASFSEAAMDAMARRKHKVPNWYLDVSLIRKYWE
EEECCCCCCEEECCCCCEECCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHC
GSPRVYHHTAPINMYYGLHQALDNLLTEGLDAAFARHKAMHHRLADGLAELGFSLYVKEG
CCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECC
AAPQVNLFIPPAGVDANALRACLREKHKIEVAGGLGALAGKVIRVGVMGEGARPEAIDKL
CCCEEEEEECCCCCCHHHHHHHHHHCCEEEEECCHHHHHHHEEEEEECCCCCCHHHHHHH
LAAVRACLGR
HHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377; 11344136 [H]