Click here to switch to the map view.

The map label for this gene is ktrA [H]

Identifier: 220903905

GI number: 220903905

Start: 759543

End: 760202

Strand: Direct

Name: ktrA [H]

Synonym: Ddes_0630

Alternate gene names: 220903905

Gene position: 759543-760202 (Clockwise)

Preceding gene: 220903904

Following gene: 220903907

Centisome position: 26.43

GC content: 56.97

Gene sequence:

>660_bases
ATGGCGGAAAAGAAGCTGGAAATAGGCGTTATCGGCCTGGGCAAATTTGGCCTGCGCATGGCGACCACCCTTGTTTCCCT
TGGGCATACTGTGGTGGGCATAGATATGTCTGAAGCGCGGGTACAACGGGCCGAAGATGCGCTGGAGTCCGTCTACAAGG
CCGACGCCACCAATATCGCCGTGCTGCGCTCACTGCATGTGCAGGACCTGGACTGGGTGGTTATCAGCGTGGGAGAAAGC
GTTGAGCAGTCCCTCAGTATCACCCTCAACGTGCAGGAATTGGGCGGCCCCAAGATATGGGTCAAGGCCTCCAATGAGGA
GCACCGCAAGATTCTTCAGCGGCTGCGCGTCAATCGTGCCCTGGTTCCCGAAATGGAGGCCGCCGTCATGGCTGCCCATC
AGCTCACCTATCCGGGCATGCTGGATCTTATCCCCAAGTACGGGGGCATCGCGATTCAGGAACTGAAGGTAGACGAATGG
CACGGCAAAACGCTGGTGGAGCTTAATCTCATGCAGCGTTTCAATATTATGGTTCTGGGCATTCGTCCCGTGGGCGAGCA
TTCTTTTAACTTCGTCCCCCCGGCCATGACCGTTCTGCACAAGGGAGACACCATTGTGGTGGCGGGCAGGGCCAATTCCA
TGAGTGAACTGAAACCCTAG

Upstream 100 bases:

>100_bases
TTGCCCGGCATACCCGGCGGGGCTTGCTCCTGTCCGGTCTTTGCCGCAGCGGAACGCTTCCGGCCTTCCGGCGCGGATAC
AGCACGGAGAAAGTAAAGAT

Downstream 100 bases:

>100_bases
GTGTAGGGCAATTGCCGTCTGCAATGAGTTTATTGCAAATGCTTGCGCAGCCTGCTCGGCGAGCGCATCTTTCTTGACCT
GCTTTTGGGGAGCGAGTGCG

Product: TrkA-N domain-containing protein

Products: NA

Alternate protein names: K(+)-uptake protein ktrA [H]

Number of amino acids: Translated: 219; Mature: 218

Protein sequence:

>219_residues
MAEKKLEIGVIGLGKFGLRMATTLVSLGHTVVGIDMSEARVQRAEDALESVYKADATNIAVLRSLHVQDLDWVVISVGES
VEQSLSITLNVQELGGPKIWVKASNEEHRKILQRLRVNRALVPEMEAAVMAAHQLTYPGMLDLIPKYGGIAIQELKVDEW
HGKTLVELNLMQRFNIMVLGIRPVGEHSFNFVPPAMTVLHKGDTIVVAGRANSMSELKP

Sequences:

>Translated_219_residues
MAEKKLEIGVIGLGKFGLRMATTLVSLGHTVVGIDMSEARVQRAEDALESVYKADATNIAVLRSLHVQDLDWVVISVGES
VEQSLSITLNVQELGGPKIWVKASNEEHRKILQRLRVNRALVPEMEAAVMAAHQLTYPGMLDLIPKYGGIAIQELKVDEW
HGKTLVELNLMQRFNIMVLGIRPVGEHSFNFVPPAMTVLHKGDTIVVAGRANSMSELKP
>Mature_218_residues
AEKKLEIGVIGLGKFGLRMATTLVSLGHTVVGIDMSEARVQRAEDALESVYKADATNIAVLRSLHVQDLDWVVISVGESV
EQSLSITLNVQELGGPKIWVKASNEEHRKILQRLRVNRALVPEMEAAVMAAHQLTYPGMLDLIPKYGGIAIQELKVDEWH
GKTLVELNLMQRFNIMVLGIRPVGEHSFNFVPPAMTVLHKGDTIVVAGRANSMSELKP

Specific function: Catalytic subunit of the ktrAB potassium uptake transporter. The 2 major potassium transporter complexes KtrAB and ktrCD confer resistance to both suddenly imposed and prolonged osmotic stress [H]

COG id: COG0569

COG function: function code P; K+ transport systems, NAD-binding component

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein; Cytoplasmic side [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 RCK N-terminal domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016040
- InterPro:   IPR006037
- InterPro:   IPR003148 [H]

Pfam domain/function: PF02080 TrkA_C; PF02254 TrkA_N [H]

EC number: NA

Molecular weight: Translated: 24110; Mature: 23978

Theoretical pI: Translated: 6.90; Mature: 6.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEKKLEIGVIGLGKFGLRMATTLVSLGHTVVGIDMSEARVQRAEDALESVYKADATNIA
CCCCEEEEEEEECCHHHHHHHHHHHHCCCEEEEECHHHHHHHHHHHHHHHHHHCCCCCHH
VLRSLHVQDLDWVVISVGESVEQSLSITLNVQELGGPKIWVKASNEEHRKILQRLRVNRA
HHHHCCCCCCCEEEEECCCCCCCCEEEEEEEECCCCCEEEEECCCHHHHHHHHHHHHCCC
LVPEMEAAVMAAHQLTYPGMLDLIPKYGGIAIQELKVDEWHGKTLVELNLMQRFNIMVLG
CCCHHHHHHHHHHHCCCCCHHHHHCCCCCEEEEEEEECCCCCCEEEEEEHHHHCCEEEEE
IRPVGEHSFNFVPPAMTVLHKGDTIVVAGRANSMSELKP
EEECCCCCCCCCCCHHHEEECCCEEEEEECCCCHHHCCC
>Mature Secondary Structure 
AEKKLEIGVIGLGKFGLRMATTLVSLGHTVVGIDMSEARVQRAEDALESVYKADATNIA
CCCEEEEEEEECCHHHHHHHHHHHHCCCEEEEECHHHHHHHHHHHHHHHHHHCCCCCHH
VLRSLHVQDLDWVVISVGESVEQSLSITLNVQELGGPKIWVKASNEEHRKILQRLRVNRA
HHHHCCCCCCCEEEEECCCCCCCCEEEEEEEECCCCCEEEEECCCHHHHHHHHHHHHCCC
LVPEMEAAVMAAHQLTYPGMLDLIPKYGGIAIQELKVDEWHGKTLVELNLMQRFNIMVLG
CCCHHHHHHHHHHHCCCCCHHHHHCCCCCEEEEEEEECCCCCCEEEEEEHHHHCCEEEEE
IRPVGEHSFNFVPPAMTVLHKGDTIVVAGRANSMSELKP
EEECCCCCCCCCCCHHHEEECCCEEEEEECCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9384377; 12086676 [H]