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The map label for this gene is fabZ [H]

Identifier: 220903882

GI number: 220903882

Start: 733571

End: 734038

Strand: Reverse

Name: fabZ [H]

Synonym: Ddes_0607

Alternate gene names: 220903882

Gene position: 734038-733571 (Counterclockwise)

Preceding gene: 220903883

Following gene: 220903880

Centisome position: 25.55

GC content: 58.76

Gene sequence:

>468_bases
ATGCAGGATTCAGTTCCACAGAGCCAGAGCATGGACATACAGCGCATCTTGCGCCTGCTGCCCCACCGCTACCCCTTCCT
GCTGGTGGACAGGGTGGTGGAATGCGTTGCCGGTTCGCATATCAAGGCGTACAAAAACATCACATTCAACGAGCCGTTTT
TTCAGGGGCATTTTCCCGGCGCGCCCATTATGCCCGGTGTGCTCATTCTTGAGGCCCTGGCCCAGACAGGCGGCCTGCTG
GCTGCATCAGGCATGGGCGACCTGGACGACAAGCTTTTTCTCTTCACCGGGCTTGACGGCGTCAAGTTCCGCCGTCAAGT
GGTCCCCGGCGATCGCCTGGACCTCGAGTGTTCCAACATCCGCATGAAACTCAAACTTTGCAAGATGGAAGCCCGCGCCT
TTGTAGATGGCAAGCTGGCTGCGGAAGCACAGATCACCGCCGCCATCGGCGACAGGCCCAAAGACTGA

Upstream 100 bases:

>100_bases
CATCACAAAGATAAAAACTTCCAGTGGGCGCAAGGCAAAGCGCCGCAGGGGCGATGCCGCCGTCACACACACGCCAAATT
CGCCAGGAGGCCAGAACAAT

Downstream 100 bases:

>100_bases
ACACACGCTGAAGAGCGCTGAAAACATTCAAGCATACAAAAGCCCGTTTGCAGCCTGGGGATAATGCTCCCCCGGCTGCA
AACGGGCTTTGCCTCAACCG

Product: beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ

Products: NA

Alternate protein names: (3R)-hydroxymyristoyl ACP dehydrase [H]

Number of amino acids: Translated: 155; Mature: 155

Protein sequence:

>155_residues
MQDSVPQSQSMDIQRILRLLPHRYPFLLVDRVVECVAGSHIKAYKNITFNEPFFQGHFPGAPIMPGVLILEALAQTGGLL
AASGMGDLDDKLFLFTGLDGVKFRRQVVPGDRLDLECSNIRMKLKLCKMEARAFVDGKLAAEAQITAAIGDRPKD

Sequences:

>Translated_155_residues
MQDSVPQSQSMDIQRILRLLPHRYPFLLVDRVVECVAGSHIKAYKNITFNEPFFQGHFPGAPIMPGVLILEALAQTGGLL
AASGMGDLDDKLFLFTGLDGVKFRRQVVPGDRLDLECSNIRMKLKLCKMEARAFVDGKLAAEAQITAAIGDRPKD
>Mature_155_residues
MQDSVPQSQSMDIQRILRLLPHRYPFLLVDRVVECVAGSHIKAYKNITFNEPFFQGHFPGAPIMPGVLILEALAQTGGLL
AASGMGDLDDKLFLFTGLDGVKFRRQVVPGDRLDLECSNIRMKLKLCKMEARAFVDGKLAAEAQITAAIGDRPKD

Specific function: Involved in saturated fatty acids biosynthesis [H]

COG id: COG0764

COG function: function code I; 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thioester dehydratase family. FabZ subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786377, Length=143, Percent_Identity=48.2517482517483, Blast_Score=146, Evalue=7e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013114
- InterPro:   IPR010084 [H]

Pfam domain/function: PF07977 FabA [H]

EC number: 4.2.1.-

Molecular weight: Translated: 17113; Mature: 17113

Theoretical pI: Translated: 8.07; Mature: 8.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQDSVPQSQSMDIQRILRLLPHRYPFLLVDRVVECVAGSHIKAYKNITFNEPFFQGHFPG
CCCCCCCCCCCCHHHHHHHCCCCCCHHHHHHHHHHHCCCCHHHHCCCCCCCCCCCCCCCC
APIMPGVLILEALAQTGGLLAASGMGDLDDKLFLFTGLDGVKFRRQVVPGDRLDLECSNI
CCCCHHHHHHHHHHHCCCEEEECCCCCCCCCEEEEECCCCHHHHHHCCCCCCCEEECCCE
RMKLKLCKMEARAFVDGKLAAEAQITAAIGDRPKD
EEEHHHHHHHHHHHCCCCCCCHHEEEEECCCCCCC
>Mature Secondary Structure
MQDSVPQSQSMDIQRILRLLPHRYPFLLVDRVVECVAGSHIKAYKNITFNEPFFQGHFPG
CCCCCCCCCCCCHHHHHHHCCCCCCHHHHHHHHHHHCCCCHHHHCCCCCCCCCCCCCCCC
APIMPGVLILEALAQTGGLLAASGMGDLDDKLFLFTGLDGVKFRRQVVPGDRLDLECSNI
CCCCHHHHHHHHHHHCCCEEEECCCCCCCCCEEEEECCCCHHHHHHCCCCCCCEEECCCE
RMKLKLCKMEARAFVDGKLAAEAQITAAIGDRPKD
EEEHHHHHHHHHHHCCCCCCCHHEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Carbon-Oxygen Lyases; Hydro-Lyases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA