Click here to switch to the map view.

The map label for this gene is trpB [H]

Identifier: 220903859

GI number: 220903859

Start: 707768

End: 708979

Strand: Reverse

Name: trpB [H]

Synonym: Ddes_0583

Alternate gene names: 220903859

Gene position: 708979-707768 (Counterclockwise)

Preceding gene: 220903861

Following gene: 220903858

Centisome position: 24.67

GC content: 61.39

Gene sequence:

>1212_bases
ATGAGCCAGCATTCCGCACCCCACGACAAACCGGACAGCAACGGCTTTTTCGGCGCTTACGGCGGCCAGTATGTTCCCGA
ACCAGTCAAGGCCCGCCTGGATGAACTGACTGCGGCTATGGAGTCTGCCCTGGCCGACCCCGGCTTCATGCAGGAACTCA
ACGACCTTTTCATCCATTATACAGGACGTCCAAGCCCTGTCTTTCACTGCGCCAACCTGAGCCATAAACTGGGCGGCGCG
CAGATATGGCTCAAGCGCGAAGACCTCAACCATCTCGGGGCGCACAAGATCAACAATACACTCGGCCAGTGCCTGCTGGC
CAAGCGTATGGGCAAAAGCCGCATCATCGCCGAAACCGGCGCGGGGCAGCACGGCGTGGCTACAGCCGCCACAGCCGCCC
TTATGGGACTTGAGTGCACCATCTGCATGGGCGAAGTGGACATGGAGCGCCAGCACCTCAACGTCATCCGCATGCGCATG
CTCGGAGCCGACGTCGTGGCGGCCACATCCGGCCAGCGCACGCTCAAGGAAGCCGTGGACGAAGCCCTTGCCCTGTGGGT
GGCGGACGATGCCATGTTTTATGTGCTGGGCTCTGCTGTGGGACCGCACCCCTATCCTTATATGGTACGCCAGTTCCAGT
CTGTGGTGGGCAGCGAGGCCCGCGAGCAGATGCTCGAAGCCTGCGGCCGTCTGCCCGATGCGGCGCTGGCCTGCGTGGGC
GGCGGTTCAAACGCCATCGGCATTTTTTCCGGCTTTGTGAATGACGCCGGCGTGCGCCTTATCGGCGTGGAACCCGGCGG
ACACGGCACGGACTACGGCCAGCACGCGGCCTCGCTCTGCCTTGGCGAACCGGGCGTACTGCACGGCTTTAATTCCTATA
TGATCAAGAATGCCGCAGGCGATGCCGGATCTGTGTATTCCATATCCGCAGGACTGGACTACCCCTCGGTAGGCCCGGAA
CACTCCATGCTCAAGGATGCGGGCCGCGCCGAATATGTCAGCATTACCGACAAGGAAGCCCTGGAAGCCTTCTTCACCCT
GTCCCGCCACGAAGGCATCATCCCGGCACTTGAATCATCCCACGCCCTGGCACATGCCATCAAGATGGCCCCGGGCATGC
CGCAGGATGCCATCCTGCTGGTCAACCTTTCCGGCCGGGGAGACAAGGATGTGGCACAAGTAGCGGAAATGATGGAAAAA
GGCGAAATCTGA

Upstream 100 bases:

>100_bases
AGCCGCCCACGCCGGGCGCAGAACCGGGCACGGCAGAACGGCGTTTTGCCGCAGACCAGGTAGCATGACGGCGACACAGC
ATCAGCAGCAAGGAGATCGC

Downstream 100 bases:

>100_bases
AAGCCACCGGCCAGTGGCTGTCGGCCCCTGTAAAAAAATACCAGAGGGGACAACGCCGTCGTGCAATGGCCCCTGCAAAT
TGGCACCGGCAGAAAAAAAC

Product: tryptophan synthase subunit beta

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 403; Mature: 402

Protein sequence:

>403_residues
MSQHSAPHDKPDSNGFFGAYGGQYVPEPVKARLDELTAAMESALADPGFMQELNDLFIHYTGRPSPVFHCANLSHKLGGA
QIWLKREDLNHLGAHKINNTLGQCLLAKRMGKSRIIAETGAGQHGVATAATAALMGLECTICMGEVDMERQHLNVIRMRM
LGADVVAATSGQRTLKEAVDEALALWVADDAMFYVLGSAVGPHPYPYMVRQFQSVVGSEAREQMLEACGRLPDAALACVG
GGSNAIGIFSGFVNDAGVRLIGVEPGGHGTDYGQHAASLCLGEPGVLHGFNSYMIKNAAGDAGSVYSISAGLDYPSVGPE
HSMLKDAGRAEYVSITDKEALEAFFTLSRHEGIIPALESSHALAHAIKMAPGMPQDAILLVNLSGRGDKDVAQVAEMMEK
GEI

Sequences:

>Translated_403_residues
MSQHSAPHDKPDSNGFFGAYGGQYVPEPVKARLDELTAAMESALADPGFMQELNDLFIHYTGRPSPVFHCANLSHKLGGA
QIWLKREDLNHLGAHKINNTLGQCLLAKRMGKSRIIAETGAGQHGVATAATAALMGLECTICMGEVDMERQHLNVIRMRM
LGADVVAATSGQRTLKEAVDEALALWVADDAMFYVLGSAVGPHPYPYMVRQFQSVVGSEAREQMLEACGRLPDAALACVG
GGSNAIGIFSGFVNDAGVRLIGVEPGGHGTDYGQHAASLCLGEPGVLHGFNSYMIKNAAGDAGSVYSISAGLDYPSVGPE
HSMLKDAGRAEYVSITDKEALEAFFTLSRHEGIIPALESSHALAHAIKMAPGMPQDAILLVNLSGRGDKDVAQVAEMMEK
GEI
>Mature_402_residues
SQHSAPHDKPDSNGFFGAYGGQYVPEPVKARLDELTAAMESALADPGFMQELNDLFIHYTGRPSPVFHCANLSHKLGGAQ
IWLKREDLNHLGAHKINNTLGQCLLAKRMGKSRIIAETGAGQHGVATAATAALMGLECTICMGEVDMERQHLNVIRMRML
GADVVAATSGQRTLKEAVDEALALWVADDAMFYVLGSAVGPHPYPYMVRQFQSVVGSEAREQMLEACGRLPDAALACVGG
GSNAIGIFSGFVNDAGVRLIGVEPGGHGTDYGQHAASLCLGEPGVLHGFNSYMIKNAAGDAGSVYSISAGLDYPSVGPEH
SMLKDAGRAEYVSITDKEALEAFFTLSRHEGIIPALESSHALAHAIKMAPGMPQDAILLVNLSGRGDKDVAQVAEMMEKG
EI

Specific function: The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine [H]

COG id: COG0133

COG function: function code E; Tryptophan synthase beta chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trpB family [H]

Homologues:

Organism=Escherichia coli, GI1787515, Length=393, Percent_Identity=55.470737913486, Blast_Score=427, Evalue=1e-121,
Organism=Saccharomyces cerevisiae, GI6321412, Length=386, Percent_Identity=54.1450777202073, Blast_Score=426, Evalue=1e-120,

Paralogues:

None

Copy number: 360 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 5,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001926
- InterPro:   IPR006653
- InterPro:   IPR006654
- InterPro:   IPR023026 [H]

Pfam domain/function: PF00291 PALP [H]

EC number: =4.2.1.20 [H]

Molecular weight: Translated: 42728; Mature: 42597

Theoretical pI: Translated: 5.64; Mature: 5.64

Prosite motif: PS00168 TRP_SYNTHASE_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQHSAPHDKPDSNGFFGAYGGQYVPEPVKARLDELTAAMESALADPGFMQELNDLFIHY
CCCCCCCCCCCCCCCEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHCEEEEE
TGRPSPVFHCANLSHKLGGAQIWLKREDLNHLGAHKINNTLGQCLLAKRMGKSRIIAETG
CCCCCCEEEECCCHHCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECC
AGQHGVATAATAALMGLECTICMGEVDMERQHLNVIRMRMLGADVVAATSGQRTLKEAVD
CCCCCHHHHHHHHHHCCEEEEEECCCHHHHHHHHHHHHHHHCCHHEEECCCHHHHHHHHH
EALALWVADDAMFYVLGSAVGPHPYPYMVRQFQSVVGSEAREQMLEACGRLPDAALACVG
HHHHHHHCCCHHHHHHHCCCCCCCCHHHHHHHHHHHCHHHHHHHHHHHCCCCCHHEEEEC
GGSNAIGIFSGFVNDAGVRLIGVEPGGHGTDYGQHAASLCLGEPGVLHGFNSYMIKNAAG
CCCCEEHHHHHHHCCCCEEEEEECCCCCCCCHHHHHHHHHCCCCCHHCCCHHHHEECCCC
DAGSVYSISAGLDYPSVGPEHSMLKDAGRAEYVSITDKEALEAFFTLSRHEGIIPALESS
CCCCEEEEECCCCCCCCCCCHHHHHHCCCCEEEEECCHHHHHHHHHHHHCCCCCCCHHCH
HALAHAIKMAPGMPQDAILLVNLSGRGDKDVAQVAEMMEKGEI
HHHHHHHHHCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SQHSAPHDKPDSNGFFGAYGGQYVPEPVKARLDELTAAMESALADPGFMQELNDLFIHY
CCCCCCCCCCCCCCEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHCEEEEE
TGRPSPVFHCANLSHKLGGAQIWLKREDLNHLGAHKINNTLGQCLLAKRMGKSRIIAETG
CCCCCCEEEECCCHHCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECC
AGQHGVATAATAALMGLECTICMGEVDMERQHLNVIRMRMLGADVVAATSGQRTLKEAVD
CCCCCHHHHHHHHHHCCEEEEEECCCHHHHHHHHHHHHHHHCCHHEEECCCHHHHHHHHH
EALALWVADDAMFYVLGSAVGPHPYPYMVRQFQSVVGSEAREQMLEACGRLPDAALACVG
HHHHHHHCCCHHHHHHHCCCCCCCCHHHHHHHHHHHCHHHHHHHHHHHCCCCCHHEEEEC
GGSNAIGIFSGFVNDAGVRLIGVEPGGHGTDYGQHAASLCLGEPGVLHGFNSYMIKNAAG
CCCCEEHHHHHHHCCCCEEEEEECCCCCCCCHHHHHHHHHCCCCCHHCCCHHHHEECCCC
DAGSVYSISAGLDYPSVGPEHSMLKDAGRAEYVSITDKEALEAFFTLSRHEGIIPALESS
CCCCEEEEECCCCCCCCCCCHHHHHHCCCCEEEEECCHHHHHHHHHHHHCCCCCCCHHCH
HALAHAIKMAPGMPQDAILLVNLSGRGDKDVAQVAEMMEKGEI
HHHHHHHHHCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA