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The map label for this gene is paaK [H]

Identifier: 220903835

GI number: 220903835

Start: 676786

End: 678090

Strand: Reverse

Name: paaK [H]

Synonym: Ddes_0559

Alternate gene names: 220903835

Gene position: 678090-676786 (Counterclockwise)

Preceding gene: 220903840

Following gene: 220903828

Centisome position: 23.6

GC content: 60.61

Gene sequence:

>1305_bases
GTGCTTTTCGACATCAAACAGGAAACCCTGCCCCGCGAGGAAATGGAAGCATTGCAGTTGCGTCGTCTGCGCGACCTGTG
CAACCGCGTTTACGCCAACGTGCCTTTCTACCGCAAACGCTTTGACGAAGCGGGCATATCCCCCGCAGACATCAAGTCGC
TGGCCGATCTGAAGCTTCTGCCCTTCACCGAAAAACAGGACCTGCGCGACTACTACCCTTTCGGCCTTTTTGCCGTGCCG
CGCGACCATATCGTGCGTCTTCACGCCTCCAGCGGAACAACGGGCAAGGCCGTGGTAGTGGGCTACACAGCCCGCGACCT
TGAAACCTGGGCCGAACTTATGGCCCGCAGCATGTCCGCCGCAGGCGTCAGCCGCTCGGATGTGGTACATATAGCTTATG
GCTACGGCCTTTTTACCGGCGGGCTTGGGGCGCACTACGGCGCGGAACGCATCGGCGCCACGGTGGTTCCCGCGTCCGGC
GGCGCCACACGCCGTCAGGCGCACCTGATGCGCGACTTCGGAGCCACCGTGCTGTGCGCCACCCCCTCTTACGCCCTGCA
CCTCTGGGAAGCCGCCAACGAGGCCGGGGTGGATTTTCGCGAACTGTCGCTGCGCACAGGCATTTTCGGCGCGGAGCCAT
GGTCCGAAGCCATGCGCCGTGACATTGAGGAAAAGATGGGCATGGACGCCATGAACATCTACGGCCTGTCTGAAATAATG
GGACCCGGCGTGGCAATGGAATGCGTTGAGGCAAAGCACGGTATGCACCTGTGGGAAGACCACATCCTGCCGGAAATTAT
CGACCCCGTCACCGGCGAGCAGCTGCCTCCGGGCCAGGTCGGCGAACTGGTGCTGACCACCCTCACCAAAGAGGGCATAC
CCATGCTGCGCTACCGCACCCGCGACCTCACAAGCCTTGATTATACCCCCTGCCGCTGCGGGCGCACCCATGTGCGCATT
TCGCGTCTTCAGGGCCGCAGCGACGACATGCTTATCATCCGCGGGGTCAATGTCTTTCCGCAGCAGATCGAAGGCCTGCT
TATGGAAAGCGACGGCCTTACGCCCAACTATCAGATCATTGTGGGCACATCCAACAACCTCGACACCCTTGAGGTGCGTG
TGGAAGTCAGCGACACCCTGTTTGCCGACGAAATACGCAAACTGCAAATGCTTGAGAACCGCCTGCAAAAAAGCATCAAA
GAATTTCTGGGTGTTTCGGCCAAGGTGCGCCTGATGGAACCGCGCTCCATCCAGCGCTCTGAAGGCAAGGCCCAGCGCAT
CGTGGACCAGCGCGAAAAGCCGTAG

Upstream 100 bases:

>100_bases
TGCGGCATACCGGAAAGGGTTTGCACACGGCAACGCCGTTTTTCATCTTTGTTATTGACGGCCCAAGGCCGCCGCCAAAA
GCCAGCTAAAGGAGAGGGCC

Downstream 100 bases:

>100_bases
CACACGGCAGATGCAGGACTTCAGACGGGCCGTTATCCACGGCCCGTCCTGCGTTTTATGAGCCCCGGCTTTTCATGCAG
TTTTTGCCCGGTTCGGCATA

Product: Phenylacetate--CoA ligase

Products: NA

Alternate protein names: Phenylacetyl-CoA ligase; PA-CoA ligase [H]

Number of amino acids: Translated: 434; Mature: 434

Protein sequence:

>434_residues
MLFDIKQETLPREEMEALQLRRLRDLCNRVYANVPFYRKRFDEAGISPADIKSLADLKLLPFTEKQDLRDYYPFGLFAVP
RDHIVRLHASSGTTGKAVVVGYTARDLETWAELMARSMSAAGVSRSDVVHIAYGYGLFTGGLGAHYGAERIGATVVPASG
GATRRQAHLMRDFGATVLCATPSYALHLWEAANEAGVDFRELSLRTGIFGAEPWSEAMRRDIEEKMGMDAMNIYGLSEIM
GPGVAMECVEAKHGMHLWEDHILPEIIDPVTGEQLPPGQVGELVLTTLTKEGIPMLRYRTRDLTSLDYTPCRCGRTHVRI
SRLQGRSDDMLIIRGVNVFPQQIEGLLMESDGLTPNYQIIVGTSNNLDTLEVRVEVSDTLFADEIRKLQMLENRLQKSIK
EFLGVSAKVRLMEPRSIQRSEGKAQRIVDQREKP

Sequences:

>Translated_434_residues
MLFDIKQETLPREEMEALQLRRLRDLCNRVYANVPFYRKRFDEAGISPADIKSLADLKLLPFTEKQDLRDYYPFGLFAVP
RDHIVRLHASSGTTGKAVVVGYTARDLETWAELMARSMSAAGVSRSDVVHIAYGYGLFTGGLGAHYGAERIGATVVPASG
GATRRQAHLMRDFGATVLCATPSYALHLWEAANEAGVDFRELSLRTGIFGAEPWSEAMRRDIEEKMGMDAMNIYGLSEIM
GPGVAMECVEAKHGMHLWEDHILPEIIDPVTGEQLPPGQVGELVLTTLTKEGIPMLRYRTRDLTSLDYTPCRCGRTHVRI
SRLQGRSDDMLIIRGVNVFPQQIEGLLMESDGLTPNYQIIVGTSNNLDTLEVRVEVSDTLFADEIRKLQMLENRLQKSIK
EFLGVSAKVRLMEPRSIQRSEGKAQRIVDQREKP
>Mature_434_residues
MLFDIKQETLPREEMEALQLRRLRDLCNRVYANVPFYRKRFDEAGISPADIKSLADLKLLPFTEKQDLRDYYPFGLFAVP
RDHIVRLHASSGTTGKAVVVGYTARDLETWAELMARSMSAAGVSRSDVVHIAYGYGLFTGGLGAHYGAERIGATVVPASG
GATRRQAHLMRDFGATVLCATPSYALHLWEAANEAGVDFRELSLRTGIFGAEPWSEAMRRDIEEKMGMDAMNIYGLSEIM
GPGVAMECVEAKHGMHLWEDHILPEIIDPVTGEQLPPGQVGELVLTTLTKEGIPMLRYRTRDLTSLDYTPCRCGRTHVRI
SRLQGRSDDMLIIRGVNVFPQQIEGLLMESDGLTPNYQIIVGTSNNLDTLEVRVEVSDTLFADEIRKLQMLENRLQKSIK
EFLGVSAKVRLMEPRSIQRSEGKAQRIVDQREKP

Specific function: Catalyzes the activation of phenylacetic acid to phenylacetyl-CoA [H]

COG id: COG1541

COG function: function code H; Coenzyme F390 synthetase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1787664, Length=426, Percent_Identity=52.5821596244132, Blast_Score=451, Evalue=1e-128,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000873
- InterPro:   IPR011880 [H]

Pfam domain/function: PF00501 AMP-binding [H]

EC number: =6.2.1.30 [H]

Molecular weight: Translated: 48628; Mature: 48628

Theoretical pI: Translated: 6.36; Mature: 6.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLFDIKQETLPREEMEALQLRRLRDLCNRVYANVPFYRKRFDEAGISPADIKSLADLKLL
CCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCHHHHHHHHCCEEC
PFTEKQDLRDYYPFGLFAVPRDHIVRLHASSGTTGKAVVVGYTARDLETWAELMARSMSA
CCCCHHHHHHHCCCCEEECCCCCEEEEECCCCCCCCEEEEEECHHHHHHHHHHHHHHHHH
AGVSRSDVVHIAYGYGLFTGGLGAHYGAERIGATVVPASGGATRRQAHLMRDFGATVLCA
CCCCCCCEEEEEECCHHHCCCCCHHCCHHHHCCEEEECCCCCHHHHHHHHHHCCCEEEEE
TPSYALHLWEAANEAGVDFRELSLRTGIFGAEPWSEAMRRDIEEKMGMDAMNIYGLSEIM
CCCHHHHHHHHCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCHHHHCCHHHHH
GPGVAMECVEAKHGMHLWEDHILPEIIDPVTGEQLPPGQVGELVLTTLTKEGIPMLRYRT
CCCHHHHHHHHHCCCHHHHHCCCHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEEC
RDLTSLDYTPCRCGRTHVRISRLQGRSDDMLIIRGVNVFPQQIEGLLMESDGLTPNYQII
CCCCCCCCCCCCCCCCCEEEEECCCCCCCEEEEECCCCCHHHHHCEEEECCCCCCCEEEE
VGTSNNLDTLEVRVEVSDTLFADEIRKLQMLENRLQKSIKEFLGVSAKVRLMEPRSIQRS
EECCCCCEEEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCHHC
EGKAQRIVDQREKP
CCHHHHHHHHCCCC
>Mature Secondary Structure
MLFDIKQETLPREEMEALQLRRLRDLCNRVYANVPFYRKRFDEAGISPADIKSLADLKLL
CCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCHHHHHHHHCCEEC
PFTEKQDLRDYYPFGLFAVPRDHIVRLHASSGTTGKAVVVGYTARDLETWAELMARSMSA
CCCCHHHHHHHCCCCEEECCCCCEEEEECCCCCCCCEEEEEECHHHHHHHHHHHHHHHHH
AGVSRSDVVHIAYGYGLFTGGLGAHYGAERIGATVVPASGGATRRQAHLMRDFGATVLCA
CCCCCCCEEEEEECCHHHCCCCCHHCCHHHHCCEEEECCCCCHHHHHHHHHHCCCEEEEE
TPSYALHLWEAANEAGVDFRELSLRTGIFGAEPWSEAMRRDIEEKMGMDAMNIYGLSEIM
CCCHHHHHHHHCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCHHHHCCHHHHH
GPGVAMECVEAKHGMHLWEDHILPEIIDPVTGEQLPPGQVGELVLTTLTKEGIPMLRYRT
CCCHHHHHHHHHCCCHHHHHCCCHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEEC
RDLTSLDYTPCRCGRTHVRISRLQGRSDDMLIIRGVNVFPQQIEGLLMESDGLTPNYQII
CCCCCCCCCCCCCCCCCEEEEECCCCCCCEEEEECCCCCHHHHHCEEEECCCCCCCEEEE
VGTSNNLDTLEVRVEVSDTLFADEIRKLQMLENRLQKSIKEFLGVSAKVRLMEPRSIQRS
EECCCCCEEEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCHHC
EGKAQRIVDQREKP
CCHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9748275; 9278503; 10766858 [H]