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The map label for this gene is gmr [H]

Identifier: 220903787

GI number: 220903787

Start: 616990

End: 619287

Strand: Reverse

Name: gmr [H]

Synonym: Ddes_0510

Alternate gene names: 220903787

Gene position: 619287-616990 (Counterclockwise)

Preceding gene: 220903789

Following gene: 220903785

Centisome position: 21.55

GC content: 54.57

Gene sequence:

>2298_bases
ATGGTCAAGTCGTCCAAAACCTTCATAGCTATCGTTGTTCTCGCGATGTTATTCACCGCGCTGCTCATAGTGGTGCGCGA
ATACACCGTGGAAACAACACGCCATCTGTCACAGGACATCACTACCCGGCTTGCCGAAGTGAGCCTGCGTGTGGCCGACG
ACTTTGAACACAGCATTGACAACAAACTGACTGAATTGCAAGGCATTACCGGTTTTCTGGCTAAAGAGGACTGCCTGCCC
CGCAAAGACTGTGTGCTGCATTATGCCCCGCTGCTGCGTGCCGCCGGCCTGAAAAGGTTTGCCATCATCAGCCCGGACGG
CCAGGGCTTTTGCTCCATGACGGGGCTACCCATTGATATTGAACAGAACAGCAAAAAAAGCCTGTTCGAACGTGCCCTGG
CCGGAACAGCCAATATTGCCGCCGTGCCTGACGGCAAGGGCAGCAAGCTTGCCGTAGCGCTGCCCATACAGCGAAACAAG
GAAATTGTGGCTGTTCTCATCGGCGAACTTGAAGACGAGCCGATGAAAAAAAGCCTGTTTACCAGGGCATTTGGCGATAA
AACCTGTAACATGGTTTTCGACGGCAACGGGCGCCTGCTGTTCTCGGCCGCGCCGCCGGGCAGTCTGGACAGGCTGTTTC
CGCAAATGGCGGAAAAAGGGCTGCCCACCTCACTGCGTGAACACCTGCTGACCATTTTTTCCGATATCACGCCCGGACCG
GACTGTCAGCGGAAAACAGACTGCCTGATAAAAGACGACCACCATTCCTACTACGTGACGCACGTGCCGCTACAGCAATA
TGGCTGGCAGGTGGTTTCGCTGCTGCCGGAAGAAGTGGTGAAGCATCTGGTGGACAGGCAGAACGACATTACCACCACGC
TGGCCTGGCGGCTGTCCATCCTGGCCGGGCTGCTGCTGGTTCTCATCATCGGCGTCATGCAAAGCTACCACCGCACCATC
CACCGCCAGCAGGAAGACTACCGCTCCATCATTGCAAGCATATCCGGCGGTGTCATCAAATTCGGCGGGCTGCACGGCAC
ATTCCAGTTTATCAGCCCCAATTTTCTCAAGATGCTGGGGTACCGCAAAGACGAGTTCGAGCAACGCTTCGGCAAGGATT
TTGCCCTGTCCATTTTTGAGCCTGACCGGGAAAACGCCCTCCGCACCATGCAGCAGCAACTGGAAGCTGGCATTCCCATT
GATGTGGAATACCGCACCAGCGCCAAAAACGGCGCTCTTATCTGGCTGTACCACAAGGGGTCTCCGGTGCAGGCCGGACC
AGGGCAAACGTATATCCAGAGCATCGTTTTTGACATTACCCAAAATAAAGAGGCCGCACAGGCCAAACGGATTTCCGACG
AGCGCTACCAGTTCATTCTGGAGCAGCATGATATTATTATCTTTGAGCAGAATCTTATTACCGGCAACTTCTCCTGTTCT
GCAAAATGGATGCAGACCTTCGGTCACGTGTTCAACATTCTTGAGCCGAATCCGGAACAGGGGCGCATTCCCGTGCATGC
AGAAGACCACGAACTGCTTGAAGATTTTCAAAAGCGCGTACATCAGGACATGCACGAACATAAAAAACAGGTTGAACTGC
GCCTGCGCGATGCCAGCGGCCTGTACCACTGGTACCGCATTGAGGCCTCAAGCCTCATCAGCGCCCAGGGCAAGCCCATA
TATTTTATCGGCATCATTACCGATATAGACCGGCAAAAAACGCTGGAACTGCGCCTGCGCACCCAGGCCACGCGCGACAG
CGCCACAGGCATGTACAACAAACGCGCCACAGAACAGGCCATTTCGCGGTTTCTGAGCCTGCACAACGGCTCCAGTATCG
GCATTTACGCCATGTTCATGATAGATTTTGACAACTTCAAGAGCATCAACGACAGGTTTGGCCATACCGTGGGTGACAAG
GCCATTTACCAGATGGCCCAGATCATCCGCCGTAACTTCCGCAGCAGTGATATTGTGGGCCGTGTGGGCGGCGATGAATT
TCTTGTTTTCTGCACCGAAACCATGCCGCTTTCCAAAATACACGAAAGAGCCGCAACCCTCGTCAGGCAATTGCGGCTTC
ATTGCGGACAGGGGGAAGACGACCAGCCCCTTACCGCCAGCGTGGGAGTGTCCTGCCACCCCACTGACGGGCATGATTTT
TCGGAACTCTACAAACATGCCGACATGGCCACCTATGAGGCCAAAAGACGGGGCCGCAACCAGTGCGTTTTTTATGCGGA
ACTGACCGCCGGGGAACAAAAAAGCGCTCACGATTCCCTTTTTCCCGAAGAGCAATGA

Upstream 100 bases:

>100_bases
ATCGCCATGATCGGACTGCTTTTTTGCATGCCCAGGGCGCTCTTCCCTTCGTCATCCAAAATGCGTATTGTTAAAAGGTT
ATTCTAACACGGGCAAACGC

Downstream 100 bases:

>100_bases
TGCCGGGCAGATGCCCATGCTGCAAGGTACCACGCAGGACATCGCACAGAGCATCGCACAATAACGCCATAAAAAAGCCC
GCATTATGCGGGCTTTTTTA

Product: PAS/PAC sensor-containing diguanylate cyclase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 765; Mature: 765

Protein sequence:

>765_residues
MVKSSKTFIAIVVLAMLFTALLIVVREYTVETTRHLSQDITTRLAEVSLRVADDFEHSIDNKLTELQGITGFLAKEDCLP
RKDCVLHYAPLLRAAGLKRFAIISPDGQGFCSMTGLPIDIEQNSKKSLFERALAGTANIAAVPDGKGSKLAVALPIQRNK
EIVAVLIGELEDEPMKKSLFTRAFGDKTCNMVFDGNGRLLFSAAPPGSLDRLFPQMAEKGLPTSLREHLLTIFSDITPGP
DCQRKTDCLIKDDHHSYYVTHVPLQQYGWQVVSLLPEEVVKHLVDRQNDITTTLAWRLSILAGLLLVLIIGVMQSYHRTI
HRQQEDYRSIIASISGGVIKFGGLHGTFQFISPNFLKMLGYRKDEFEQRFGKDFALSIFEPDRENALRTMQQQLEAGIPI
DVEYRTSAKNGALIWLYHKGSPVQAGPGQTYIQSIVFDITQNKEAAQAKRISDERYQFILEQHDIIIFEQNLITGNFSCS
AKWMQTFGHVFNILEPNPEQGRIPVHAEDHELLEDFQKRVHQDMHEHKKQVELRLRDASGLYHWYRIEASSLISAQGKPI
YFIGIITDIDRQKTLELRLRTQATRDSATGMYNKRATEQAISRFLSLHNGSSIGIYAMFMIDFDNFKSINDRFGHTVGDK
AIYQMAQIIRRNFRSSDIVGRVGGDEFLVFCTETMPLSKIHERAATLVRQLRLHCGQGEDDQPLTASVGVSCHPTDGHDF
SELYKHADMATYEAKRRGRNQCVFYAELTAGEQKSAHDSLFPEEQ

Sequences:

>Translated_765_residues
MVKSSKTFIAIVVLAMLFTALLIVVREYTVETTRHLSQDITTRLAEVSLRVADDFEHSIDNKLTELQGITGFLAKEDCLP
RKDCVLHYAPLLRAAGLKRFAIISPDGQGFCSMTGLPIDIEQNSKKSLFERALAGTANIAAVPDGKGSKLAVALPIQRNK
EIVAVLIGELEDEPMKKSLFTRAFGDKTCNMVFDGNGRLLFSAAPPGSLDRLFPQMAEKGLPTSLREHLLTIFSDITPGP
DCQRKTDCLIKDDHHSYYVTHVPLQQYGWQVVSLLPEEVVKHLVDRQNDITTTLAWRLSILAGLLLVLIIGVMQSYHRTI
HRQQEDYRSIIASISGGVIKFGGLHGTFQFISPNFLKMLGYRKDEFEQRFGKDFALSIFEPDRENALRTMQQQLEAGIPI
DVEYRTSAKNGALIWLYHKGSPVQAGPGQTYIQSIVFDITQNKEAAQAKRISDERYQFILEQHDIIIFEQNLITGNFSCS
AKWMQTFGHVFNILEPNPEQGRIPVHAEDHELLEDFQKRVHQDMHEHKKQVELRLRDASGLYHWYRIEASSLISAQGKPI
YFIGIITDIDRQKTLELRLRTQATRDSATGMYNKRATEQAISRFLSLHNGSSIGIYAMFMIDFDNFKSINDRFGHTVGDK
AIYQMAQIIRRNFRSSDIVGRVGGDEFLVFCTETMPLSKIHERAATLVRQLRLHCGQGEDDQPLTASVGVSCHPTDGHDF
SELYKHADMATYEAKRRGRNQCVFYAELTAGEQKSAHDSLFPEEQ
>Mature_765_residues
MVKSSKTFIAIVVLAMLFTALLIVVREYTVETTRHLSQDITTRLAEVSLRVADDFEHSIDNKLTELQGITGFLAKEDCLP
RKDCVLHYAPLLRAAGLKRFAIISPDGQGFCSMTGLPIDIEQNSKKSLFERALAGTANIAAVPDGKGSKLAVALPIQRNK
EIVAVLIGELEDEPMKKSLFTRAFGDKTCNMVFDGNGRLLFSAAPPGSLDRLFPQMAEKGLPTSLREHLLTIFSDITPGP
DCQRKTDCLIKDDHHSYYVTHVPLQQYGWQVVSLLPEEVVKHLVDRQNDITTTLAWRLSILAGLLLVLIIGVMQSYHRTI
HRQQEDYRSIIASISGGVIKFGGLHGTFQFISPNFLKMLGYRKDEFEQRFGKDFALSIFEPDRENALRTMQQQLEAGIPI
DVEYRTSAKNGALIWLYHKGSPVQAGPGQTYIQSIVFDITQNKEAAQAKRISDERYQFILEQHDIIIFEQNLITGNFSCS
AKWMQTFGHVFNILEPNPEQGRIPVHAEDHELLEDFQKRVHQDMHEHKKQVELRLRDASGLYHWYRIEASSLISAQGKPI
YFIGIITDIDRQKTLELRLRTQATRDSATGMYNKRATEQAISRFLSLHNGSSIGIYAMFMIDFDNFKSINDRFGHTVGDK
AIYQMAQIIRRNFRSSDIVGRVGGDEFLVFCTETMPLSKIHERAATLVRQLRLHCGQGEDDQPLTASVGVSCHPTDGHDF
SELYKHADMATYEAKRRGRNQCVFYAELTAGEQKSAHDSLFPEEQ

Specific function: Part of a 2 protein system that seems to be dedicated to transcription of csgD. This protein decreases csgD transcription and thus decreases expression of adhesive curli fimbriae genes csgEFG, csgBAC/ymaD and adrA (yaic). Activity of this protein is antag

COG id: COG2199

COG function: function code T; FOG: GGDEF domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1787541, Length=198, Percent_Identity=33.8383838383838, Blast_Score=108, Evalue=1e-24,
Organism=Escherichia coli, GI1786584, Length=174, Percent_Identity=37.9310344827586, Blast_Score=100, Evalue=3e-22,
Organism=Escherichia coli, GI145693134, Length=169, Percent_Identity=34.9112426035503, Blast_Score=93, Evalue=6e-20,
Organism=Escherichia coli, GI87082007, Length=184, Percent_Identity=33.1521739130435, Blast_Score=91, Evalue=3e-19,
Organism=Escherichia coli, GI87081881, Length=188, Percent_Identity=32.9787234042553, Blast_Score=88, Evalue=2e-18,
Organism=Escherichia coli, GI1787262, Length=169, Percent_Identity=32.5443786982249, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI1788381, Length=210, Percent_Identity=27.6190476190476, Blast_Score=83, Evalue=6e-17,
Organism=Escherichia coli, GI87081977, Length=184, Percent_Identity=32.6086956521739, Blast_Score=81, Evalue=3e-16,
Organism=Escherichia coli, GI1788085, Length=171, Percent_Identity=29.2397660818713, Blast_Score=74, Evalue=5e-14,
Organism=Escherichia coli, GI1787816, Length=229, Percent_Identity=26.6375545851528, Blast_Score=70, Evalue=5e-13,
Organism=Escherichia coli, GI87081974, Length=109, Percent_Identity=36.697247706422, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI1787802, Length=137, Percent_Identity=31.3868613138686, Blast_Score=67, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR000014
- InterPro:   IPR013767 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF; PF00989 PAS [H]

EC number: =3.1.4.52 [H]

Molecular weight: Translated: 86458; Mature: 86458

Theoretical pI: Translated: 6.96; Mature: 6.96

Prosite motif: PS50113 PAC ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVKSSKTFIAIVVLAMLFTALLIVVREYTVETTRHLSQDITTRLAEVSLRVADDFEHSID
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NKLTELQGITGFLAKEDCLPRKDCVLHYAPLLRAAGLKRFAIISPDGQGFCSMTGLPIDI
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCCCEEEECCCEEEE
EQNSKKSLFERALAGTANIAAVPDGKGSKLAVALPIQRNKEIVAVLIGELEDEPMKKSLF
CCCCHHHHHHHHHCCCCCEEECCCCCCCEEEEEECCCCCCCEEEEEECCCCCCHHHHHHH
TRAFGDKTCNMVFDGNGRLLFSAAPPGSLDRLFPQMAEKGLPTSLREHLLTIFSDITPGP
HHHCCCCCEEEEECCCCEEEEECCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCC
DCQRKTDCLIKDDHHSYYVTHVPLQQYGWQVVSLLPEEVVKHLVDRQNDITTTLAWRLSI
CCCCCCCCEEEECCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
LAGLLLVLIIGVMQSYHRTIHRQQEDYRSIIASISGGVIKFGGLHGTFQFISPNFLKMLG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCEEEECCHHHHHHHC
YRKDEFEQRFGKDFALSIFEPDRENALRTMQQQLEAGIPIDVEYRTSAKNGALIWLYHKG
CCHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHCCCCEEEEEECCCCCCCEEEEEECC
SPVQAGPGQTYIQSIVFDITQNKEAAQAKRISDERYQFILEQHDIIIFEQNLITGNFSCS
CCCCCCCCHHHHHHHHHHHHCCCHHHHHHHCCHHHHHHHHHCCCEEEEECCEEECCCCCC
AKWMQTFGHVFNILEPNPEQGRIPVHAEDHELLEDFQKRVHQDMHEHKKQVELRLRDASG
HHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCC
LYHWYRIEASSLISAQGKPIYFIGIITDIDRQKTLELRLRTQATRDSATGMYNKRATEQA
CEEEEEEEHHHHHHCCCCCEEEEEEEECCCCCCEEEEEEHHHHCCCHHCCCHHHHHHHHH
ISRFLSLHNGSSIGIYAMFMIDFDNFKSINDRFGHTVGDKAIYQMAQIIRRNFRSSDIVG
HHHHHHHCCCCCCEEEEEEEEECCCCCCHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCEE
RVGGDEFLVFCTETMPLSKIHERAATLVRQLRLHCGQGEDDQPLTASVGVSCHPTDGHDF
ECCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEECCCEECCCCCCCH
SELYKHADMATYEAKRRGRNQCVFYAELTAGEQKSAHDSLFPEEQ
HHHHHHCCHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MVKSSKTFIAIVVLAMLFTALLIVVREYTVETTRHLSQDITTRLAEVSLRVADDFEHSID
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NKLTELQGITGFLAKEDCLPRKDCVLHYAPLLRAAGLKRFAIISPDGQGFCSMTGLPIDI
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCCCEEEECCCEEEE
EQNSKKSLFERALAGTANIAAVPDGKGSKLAVALPIQRNKEIVAVLIGELEDEPMKKSLF
CCCCHHHHHHHHHCCCCCEEECCCCCCCEEEEEECCCCCCCEEEEEECCCCCCHHHHHHH
TRAFGDKTCNMVFDGNGRLLFSAAPPGSLDRLFPQMAEKGLPTSLREHLLTIFSDITPGP
HHHCCCCCEEEEECCCCEEEEECCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCC
DCQRKTDCLIKDDHHSYYVTHVPLQQYGWQVVSLLPEEVVKHLVDRQNDITTTLAWRLSI
CCCCCCCCEEEECCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
LAGLLLVLIIGVMQSYHRTIHRQQEDYRSIIASISGGVIKFGGLHGTFQFISPNFLKMLG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCEEEECCHHHHHHHC
YRKDEFEQRFGKDFALSIFEPDRENALRTMQQQLEAGIPIDVEYRTSAKNGALIWLYHKG
CCHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHCCCCEEEEEECCCCCCCEEEEEECC
SPVQAGPGQTYIQSIVFDITQNKEAAQAKRISDERYQFILEQHDIIIFEQNLITGNFSCS
CCCCCCCCHHHHHHHHHHHHCCCHHHHHHHCCHHHHHHHHHCCCEEEEECCEEECCCCCC
AKWMQTFGHVFNILEPNPEQGRIPVHAEDHELLEDFQKRVHQDMHEHKKQVELRLRDASG
HHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCC
LYHWYRIEASSLISAQGKPIYFIGIITDIDRQKTLELRLRTQATRDSATGMYNKRATEQA
CEEEEEEEHHHHHHCCCCCEEEEEEEECCCCCCEEEEEEHHHHCCCHHCCCHHHHHHHHH
ISRFLSLHNGSSIGIYAMFMIDFDNFKSINDRFGHTVGDKAIYQMAQIIRRNFRSSDIVG
HHHHHHHCCCCCCEEEEEEEEECCCCCCHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCEE
RVGGDEFLVFCTETMPLSKIHERAATLVRQLRLHCGQGEDDQPLTASVGVSCHPTDGHDF
ECCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEECCCEECCCCCCCH
SELYKHADMATYEAKRRGRNQCVFYAELTAGEQKSAHDSLFPEEQ
HHHHHHCCHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503 [H]