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The map label for this gene is infC [H]

Identifier: 220903767

GI number: 220903767

Start: 597993

End: 598523

Strand: Reverse

Name: infC [H]

Synonym: Ddes_0489

Alternate gene names: 220903767

Gene position: 598523-597993 (Counterclockwise)

Preceding gene: 220903768

Following gene: 220903766

Centisome position: 20.83

GC content: 55.74

Gene sequence:

>531_bases
ATGAGATTCCGCCGCGACATGCCGCAAGACAGCGTACGTCGCAACGAAATGATCCGCGCCCGTGAAGTGCGCGTGATCGC
CGCCGATGGCGAGCAGCTTGGTATTTTGCAACGTAACGAAGCCATTGTGATGGCCAAAGAAGCGGGCATGGACCTGGTGG
AAGTTTCTTCCAACTCCGAGCCGCCCGTTTGCCGCATAATGGATTACGGCAAGTTCAAATACGAGCAGCAGAAGAAAAAG
CAGGAAGCCAAAAAACGCCAGGCTGTGGTGCAGATCAAGGAAATCAAGGTCCGCCCCAAGACGGATGACCATGACTACGA
AACCAAGGTCCGCCACATCCGCCGCTTTCTGGAAGAAGGCGACCGCTGTAAGATCACCGTGTTTTTCAGGGGCCGTGAAA
TCGTCCATAAAGACCGCGGCATAGCCATTCTGGAGCGAGTGGTGCAAGACCTGGCCGATATTGCCAGGGTCGATCAGGAA
CCCCGCGCCGAAGGCCGCACCCTGCAGATGATGCTGGTACCCAAAAAGTAA

Upstream 100 bases:

>100_bases
AACCTGGGGCTCAAGTCCGTAGCGGAAATCGCCGCACTCATACGCACGGACGCCGAAGAGCCTTTCAAACAAGGAGGGAT
GCGCTATAGCTTCGCCTAAC

Downstream 100 bases:

>100_bases
CCGGCCTCATACGGCAAAACACATTGGAGCAGCCGGCTCTTGAGAGTACGCATTCTCAAGGCCTGAACGCGGTCAGTCCG
GCGGCGGCAGGATTACTATG

Product: translation initiation factor IF-3

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 176; Mature: 176

Protein sequence:

>176_residues
MRFRRDMPQDSVRRNEMIRAREVRVIAADGEQLGILQRNEAIVMAKEAGMDLVEVSSNSEPPVCRIMDYGKFKYEQQKKK
QEAKKRQAVVQIKEIKVRPKTDDHDYETKVRHIRRFLEEGDRCKITVFFRGREIVHKDRGIAILERVVQDLADIARVDQE
PRAEGRTLQMMLVPKK

Sequences:

>Translated_176_residues
MRFRRDMPQDSVRRNEMIRAREVRVIAADGEQLGILQRNEAIVMAKEAGMDLVEVSSNSEPPVCRIMDYGKFKYEQQKKK
QEAKKRQAVVQIKEIKVRPKTDDHDYETKVRHIRRFLEEGDRCKITVFFRGREIVHKDRGIAILERVVQDLADIARVDQE
PRAEGRTLQMMLVPKK
>Mature_176_residues
MRFRRDMPQDSVRRNEMIRAREVRVIAADGEQLGILQRNEAIVMAKEAGMDLVEVSSNSEPPVCRIMDYGKFKYEQQKKK
QEAKKRQAVVQIKEIKVRPKTDDHDYETKVRHIRRFLEEGDRCKITVFFRGREIVHKDRGIAILERVVQDLADIARVDQE
PRAEGRTLQMMLVPKK

Specific function: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins [H]

COG id: COG0290

COG function: function code J; Translation initiation factor 3 (IF-3)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the IF-3 family [H]

Homologues:

Organism=Escherichia coli, GI1788012, Length=165, Percent_Identity=56.3636363636364, Blast_Score=171, Evalue=2e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019813
- InterPro:   IPR001288
- InterPro:   IPR019815
- InterPro:   IPR019814 [H]

Pfam domain/function: PF00707 IF3_C; PF05198 IF3_N [H]

EC number: NA

Molecular weight: Translated: 20703; Mature: 20703

Theoretical pI: Translated: 10.33; Mature: 10.33

Prosite motif: PS00938 IF3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRFRRDMPQDSVRRNEMIRAREVRVIAADGEQLGILQRNEAIVMAKEAGMDLVEVSSNSE
CCCCCCCCHHHHHHHHHHHHHEEEEEEECCCEECEEECCCEEEEECCCCCEEEEECCCCC
PPVCRIMDYGKFKYEQQKKKQEAKKRQAVVQIKEIKVRPKTDDHDYETKVRHIRRFLEEG
CCEEEEECCCCCHHHHHHHHHHHHHHHHHEEHHHEEECCCCCCCCHHHHHHHHHHHHCCC
DRCKITVFFRGREIVHKDRGIAILERVVQDLADIARVDQEPRAEGRTLQMMLVPKK
CEEEEEEEECCCEEECCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEECCC
>Mature Secondary Structure
MRFRRDMPQDSVRRNEMIRAREVRVIAADGEQLGILQRNEAIVMAKEAGMDLVEVSSNSE
CCCCCCCCHHHHHHHHHHHHHEEEEEEECCCEECEEECCCEEEEECCCCCEEEEECCCCC
PPVCRIMDYGKFKYEQQKKKQEAKKRQAVVQIKEIKVRPKTDDHDYETKVRHIRRFLEEG
CCEEEEECCCCCHHHHHHHHHHHHHHHHHEEHHHEEECCCCCCCCHHHHHHHHHHHHCCC
DRCKITVFFRGREIVHKDRGIAILERVVQDLADIARVDQEPRAEGRTLQMMLVPKK
CEEEEEEEECCCEEECCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA